Compile Data Set for Download or QSAR
maximum 50k data
Found 19 Enz. Inhib. hit(s) with all data for entry = 50005903
TargetGlutamate receptor ionotropic, NMDA 1(RAT)
Merck Sharp And Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50038176(7-Chloro-3-nitro-3,4-dihydro-1H-quinolin-2-one | C...)
Affinity DataIC50:  414nMAssay Description:Binding affinity towards NMDA receptor to displace [3H]-L-689,560 from rat cortical membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, NMDA 1(RAT)
Merck Sharp And Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50030668((7-Chloro-3-nitro-2-oxo-1,2,3,4-tetrahydro-quinoli...)
Affinity DataIC50:  1.32E+3nMAssay Description:Binding affinity towards NMDA receptor to displace [3H]-L-689,560 from rat cortical membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, NMDA 1(RAT)
Merck Sharp And Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50042328(2-(7-Chloro-3-nitro-2-oxo-1,2,3,4-tetrahydro-quino...)
Affinity DataIC50:  1.84E+3nMAssay Description:Binding affinity towards NMDA receptor to displace [3H]-L-689,560 from rat cortical membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, NMDA 1(RAT)
Merck Sharp And Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50042324((7-Chloro-3-nitro-2-oxo-1,2,3,4-tetrahydro-quinoli...)
Affinity DataIC50:  2.23E+3nMAssay Description:Binding affinity towards NMDA receptor to displace [3H]-L-689,560 from rat cortical membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, NMDA 1(RAT)
Merck Sharp And Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50042336(CHEMBL115023 | N-Benzyl-2-(7-chloro-3-nitro-2-oxo-...)
Affinity DataIC50:  2.53E+3nMAssay Description:Binding affinity towards NMDA receptor to displace [3H]-L-689,560 from rat cortical membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, NMDA 1(RAT)
Merck Sharp And Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50042331(2-(7-Chloro-3-nitro-2-oxo-1,2,3,4-tetrahydro-quino...)
Affinity DataIC50:  3.72E+3nMAssay Description:Binding affinity towards NMDA receptor to displace [3H]-L-689,560 from rat cortical membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, NMDA 1(RAT)
Merck Sharp And Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50042332(7-Chloro-4-(3-methyl-[1,2,4]oxadiazol-5-ylmethyl)-...)
Affinity DataIC50:  5.59E+3nMAssay Description:Binding affinity towards NMDA receptor to displace [3H]-L-689,560 from rat cortical membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, NMDA 1(RAT)
Merck Sharp And Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50042322(2-(7-Chloro-3-nitro-2-oxo-1,2,3,4-tetrahydro-quino...)
Affinity DataIC50:  7.43E+3nMAssay Description:Binding affinity towards NMDA receptor to displace [3H]-L-689,560 from rat cortical membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, NMDA 1(RAT)
Merck Sharp And Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50042326((7-Chloro-3-cyano-2-oxo-1,2,3,4-tetrahydro-quinoli...)
Affinity DataIC50:  1.20E+4nMAssay Description:Binding affinity towards NMDA receptor to displace [3H]-L-689,560 from rat cortical membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, NMDA 1(RAT)
Merck Sharp And Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50042337(2-(7-Chloro-3-nitro-2-oxo-1,2,3,4-tetrahydro-quino...)
Affinity DataIC50:  1.24E+4nMAssay Description:Binding affinity towards NMDA receptor to displace [3H]-L-689,560 from rat cortical membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, NMDA 1(RAT)
Merck Sharp And Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50042329((3-Nitro-2-oxo-1,2,3,4-tetrahydro-quinolin-4-yl)-a...)
Affinity DataIC50:  2.86E+4nMAssay Description:Binding affinity towards NMDA receptor to displace [3H]-L-689,560 from rat cortical membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, NMDA 1(RAT)
Merck Sharp And Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50042333((7-Chloro-3-nitro-2-oxo-1,2-dihydro-quinolin-4-yl)...)
Affinity DataIC50:  9.44E+4nMAssay Description:Binding affinity towards NMDA receptor to displace [3H]-L-689,560 from rat cortical membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, NMDA 1(RAT)
Merck Sharp And Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50042330((3-Benzoyl-7-chloro-2-oxo-1,2,3,4-tetrahydro-quino...)
Affinity DataIC50: >1.00E+5nMAssay Description:Binding affinity towards NMDA receptor to displace [3H]-L-689,560 from rat cortical membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, NMDA 1(RAT)
Merck Sharp And Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50042334((7-Chloro-2-oxo-1,2,3,4-tetrahydro-quinolin-4-yl)-...)
Affinity DataIC50: >1.00E+5nMAssay Description:Binding affinity towards NMDA receptor to displace [3H]-L-689,560 from rat cortical membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, NMDA 1(RAT)
Merck Sharp And Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50042323(7-Chloro-4-methoxycarbonylmethyl-2-oxo-1,2,3,4-tet...)
Affinity DataIC50: >1.00E+5nMAssay Description:Binding affinity towards NMDA receptor to displace [3H]-L-689,560 from rat cortical membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, NMDA 1(RAT)
Merck Sharp And Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50042338(CHEMBL116384 | [7-Chloro-3-(4-nitro-benzenesulfony...)
Affinity DataIC50: >1.00E+5nMAssay Description:Binding affinity towards NMDA receptor to displace [3H]-L-689,560 from rat cortical membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, NMDA 1(RAT)
Merck Sharp And Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50042325(7-Chloro-4-methoxycarbonylmethyl-2-oxo-1,2-dihydro...)
Affinity DataIC50: >1.00E+5nMAssay Description:Binding affinity towards NMDA receptor to displace [3H]-L-689,560 from rat cortical membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, NMDA 1(RAT)
Merck Sharp And Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50042327((3-Benzenesulfonyl-7-chloro-2-oxo-1,2,3,4-tetrahyd...)
Affinity DataIC50: >1.00E+5nMAssay Description:Binding affinity towards NMDA receptor to displace [3H]-L-689,560 from rat cortical membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, NMDA 1(RAT)
Merck Sharp And Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50042335((7-Chloro-3-methanesulfonyl-2-oxo-1,2,3,4-tetrahyd...)
Affinity DataIC50: >1.00E+5nMAssay Description:Binding affinity towards NMDA receptor to displace [3H]-L-689,560 from rat cortical membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed