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Found 31 Enz. Inhib. hit(s) with all data for entry = 50006010
TargetInterstitial collagenase(Homo sapiens (Human))
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50043734(((R)-1-{(S)-1-[(S)-2-(1H-Indol-3-yl)-1-methylcarba...)
Affinity DataIC50:  50nMAssay Description:Inhibition of degradation of radiolabeled rat skin type I collagen by semipurified human lung fibroblast collagenaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterstitial collagenase(Homo sapiens (Human))
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50043733(((R)-1-{(S)-1-[(S)-2-(1H-Benzoimidazol-2-yl)-1-met...)
Affinity DataIC50:  150nMAssay Description:Inhibition of degradation of radiolabeled rat skin type I collagen by semipurified human lung fibroblast collagenaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterstitial collagenase(Homo sapiens (Human))
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50043745(CHEMBL47907 | {(R)-1-[(S)-3-Methyl-1-((S)-1-methyl...)
Affinity DataIC50:  230nMAssay Description:Inhibition of degradation of radiolabeled rat skin type I collagen by semipurified human lung fibroblast collagenaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterstitial collagenase(Homo sapiens (Human))
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50043755(CHEMBL416095 | {(S)-1-[(S)-3-Methyl-1-((S)-1-methy...)
Affinity DataIC50:  240nMAssay Description:Inhibition of degradation of radiolabeled rat skin type I collagen by semipurified human lung fibroblast collagenaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterstitial collagenase(Homo sapiens (Human))
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50043732(((S)-1-{(S)-1-[(S)-2-(4-Methoxy-phenyl)-1-methylca...)
Affinity DataIC50:  260nMAssay Description:Inhibition of degradation of radiolabeled rat skin type I collagen by semipurified human lung fibroblast collagenaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterstitial collagenase(Homo sapiens (Human))
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50043728(CHEMBL295260 | {(R)-1-[(S)-1-((S)-4-Guanidino-1-me...)
Affinity DataIC50:  290nMAssay Description:Inhibition of degradation of radiolabeled rat skin type I collagen by semipurified human lung fibroblast collagenaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterstitial collagenase(Homo sapiens (Human))
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50043744(((S)-1-{(S)-1-[(S)-2-(4-Methoxy-phenyl)-1-methylca...)
Affinity DataIC50:  300nMAssay Description:Inhibition of degradation of radiolabeled rat skin type I collagen by semipurified human lung fibroblast collagenaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterstitial collagenase(Homo sapiens (Human))
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50043740((S)-4-Benzyloxycarbonylamino-2-{(S)-1-[(S)-2-(4-me...)
Affinity DataIC50:  350nMAssay Description:Inhibition of degradation of radiolabeled rat skin type I collagen by semipurified human lung fibroblast collagenaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterstitial collagenase(Homo sapiens (Human))
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50043750(CHEMBL45577 | {(R)-1-[(S)-3-Methyl-1-((S)-1-methyl...)
Affinity DataIC50:  400nMAssay Description:Inhibition of degradation of radiolabeled rat skin type I collagen by semipurified human lung fibroblast collagenaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterstitial collagenase(Homo sapiens (Human))
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50043738(((R)-1-{(S)-1-[(S)-2-(4-Methoxy-phenyl)-1-methylca...)
Affinity DataIC50:  470nMAssay Description:Inhibition of degradation of radiolabeled rat skin type I collagen by semipurified human lung fibroblast collagenaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterstitial collagenase(Homo sapiens (Human))
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50043737(CHEMBL47627 | {(R)-1-[(S)-1-((S)-4-Dimethylamino-1...)
Affinity DataIC50:  490nMAssay Description:Inhibition of degradation of radiolabeled rat skin type I collagen by semipurified human lung fibroblast collagenaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterstitial collagenase(Homo sapiens (Human))
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50043752(((R)-1-{(S)-1-[(S)-2-(4-Methoxy-phenyl)-1-methylca...)
Affinity DataIC50:  520nMAssay Description:Inhibition of degradation of radiolabeled rat skin type I collagen by semipurified human lung fibroblast collagenaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterstitial collagenase(Homo sapiens (Human))
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50043754(CHEMBL46083 | {(S)-1-[(S)-1-((S)-5-Amino-1-methylc...)
Affinity DataIC50:  740nMAssay Description:Inhibition of degradation of radiolabeled rat skin type I collagen by semipurified human lung fibroblast collagenaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterstitial collagenase(Homo sapiens (Human))
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50043751(CHEMBL296894 | {(R)-1-[(S)-3-Methyl-1-((S)-1-methy...)
Affinity DataIC50:  760nMAssay Description:Inhibition of degradation of radiolabeled rat skin type I collagen by semipurified human lung fibroblast collagenaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterstitial collagenase(Homo sapiens (Human))
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50043730(((R)-1-{(S)-3-Methyl-1-[(S)-1-methylcarbamoyl-2-(2...)
Affinity DataIC50:  1.36E+3nMAssay Description:Inhibition of degradation of radiolabeled rat skin type I collagen by semipurified human lung fibroblast collagenaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterstitial collagenase(Homo sapiens (Human))
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50043748(CHEMBL48043 | {(R)-3-Methyl-1-[(S)-3-methyl-1-((S)...)
Affinity DataIC50:  1.56E+3nMAssay Description:Inhibition of degradation of radiolabeled rat skin type I collagen by semipurified human lung fibroblast collagenaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterstitial collagenase(Homo sapiens (Human))
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50043743(CHEMBL443261 | {(S)-1-[(S)-3-Methyl-1-((S)-1-methy...)
Affinity DataIC50:  1.82E+3nMAssay Description:Inhibition of degradation of radiolabeled rat skin type I collagen by semipurified human lung fibroblast collagenaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterstitial collagenase(Homo sapiens (Human))
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50043739((1-{1-[(S)-2-(4-Methoxy-phenyl)-1-methylcarbamoyl-...)
Affinity DataIC50:  2.90E+3nMAssay Description:Inhibition of degradation of radiolabeled rat skin type I collagen by semipurified human lung fibroblast collagenaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterstitial collagenase(Homo sapiens (Human))
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50043757((1-{1-[(S)-2-(4-Methoxy-phenyl)-1-methylcarbamoyl-...)
Affinity DataIC50:  2.90E+3nMAssay Description:Inhibition of degradation of radiolabeled rat skin type I collagen by semipurified human lung fibroblast collagenaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterstitial collagenase(Homo sapiens (Human))
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50043736((S)-2-{(S)-1-[(S)-2-(4-Methoxy-phenyl)-1-methylcar...)
Affinity DataIC50:  3.46E+3nMAssay Description:Inhibition of degradation of radiolabeled rat skin type I collagen by semipurified human lung fibroblast collagenaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterstitial collagenase(Homo sapiens (Human))
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50043727(CHEMBL294997 | {(R)-1-[(S)-1-((S)-5-Amino-1-methyl...)
Affinity DataIC50:  4.32E+3nMAssay Description:Inhibition of degradation of radiolabeled rat skin type I collagen by semipurified human lung fibroblast collagenaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterstitial collagenase(Homo sapiens (Human))
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50043747(CHEMBL416255 | {(S)-1-[(R)-3-Methyl-1-((S)-1-methy...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of degradation of radiolabeled rat skin type I collagen by semipurified human lung fibroblast collagenaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterstitial collagenase(Homo sapiens (Human))
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50043735((R)-2-{(S)-1-[(S)-2-(4-Methoxy-phenyl)-1-methylcar...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of degradation of radiolabeled rat skin type I collagen by semipurified human lung fibroblast collagenaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterstitial collagenase(Homo sapiens (Human))
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50043742(CHEMBL297355 | {(R)-1-[(R)-3-Methyl-1-((S)-1-methy...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of degradation of radiolabeled rat skin type I collagen by semipurified human lung fibroblast collagenaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterstitial collagenase(Homo sapiens (Human))
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50043746(((R)-1-{(R)-1-[(S)-2-(4-Methoxy-phenyl)-1-methylca...)
Affinity DataIC50:  1.56E+4nMAssay Description:Inhibition of degradation of radiolabeled rat skin type I collagen by semipurified human lung fibroblast collagenaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterstitial collagenase(Homo sapiens (Human))
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50043741((1-{1-[(S)-2-(4-Methoxy-phenyl)-1-methylcarbamoyl-...)
Affinity DataIC50:  1.57E+4nMAssay Description:Inhibition of degradation of radiolabeled rat skin type I collagen by semipurified human lung fibroblast collagenaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterstitial collagenase(Homo sapiens (Human))
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50043729(CHEMBL44903 | {(S)-2-[(S)-2-(4-Methoxy-phenyl)-1-m...)
Affinity DataIC50:  3.70E+4nMAssay Description:Inhibition of degradation of radiolabeled rat skin type I collagen by semipurified human lung fibroblast collagenaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterstitial collagenase(Homo sapiens (Human))
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50043753(((S)-1-{(R)-1-[(S)-2-(4-Methoxy-phenyl)-1-methylca...)
Affinity DataIC50:  3.93E+4nMAssay Description:Inhibition of degradation of radiolabeled rat skin type I collagen by semipurified human lung fibroblast collagenaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterstitial collagenase(Homo sapiens (Human))
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50043731((1-{1-[(S)-2-(4-Methoxy-phenyl)-1-methylcarbamoyl-...)
Affinity DataIC50:  4.12E+4nMAssay Description:Inhibition of degradation of radiolabeled rat skin type I collagen by semipurified human lung fibroblast collagenaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterstitial collagenase(Homo sapiens (Human))
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50043756((1-{1-[(S)-2-(4-Methoxy-phenyl)-1-methylcarbamoyl-...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of degradation of radiolabeled rat skin type I collagen by semipurified human lung fibroblast collagenaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterstitial collagenase(Homo sapiens (Human))
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50043749((1-{1-[(S)-2-(4-Methoxy-phenyl)-1-methylcarbamoyl-...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of degradation of radiolabeled rat skin type I collagen by semipurified human lung fibroblast collagenaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed