Compile Data Set for Download or QSAR
maximum 50k data
Found 8 Enz. Inhib. hit(s) with all data for entry = 50006085
TargetSigma non-opioid intracellular receptor 1(RAT)
National Institute Of Diabetes And Digestive And Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50044427(1-methyl-16-azatetracyclo[7.6.1.02,7.010,15]hexade...)
Affinity DataKi:  4.82E+3nMAssay Description:Tested for invitro inhibition of the displacement of (+)-[3H]-pentazocine from sigma opioid receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGamma-aminobutyric acid receptor subunit alpha-2(Rattus norvegicus (Rat))
National Institute Of Diabetes And Digestive And Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50044427(1-methyl-16-azatetracyclo[7.6.1.02,7.010,15]hexade...)
Affinity DataKi:  6.95E+3nMAssay Description:Tested for invitro inhibition of the displacement of [3H]-mazindol from GABA receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGamma-aminobutyric acid receptor subunit alpha-2(Rattus norvegicus (Rat))
National Institute Of Diabetes And Digestive And Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50000663((+)-1-methyl-16-azatetracyclo[7.6.1.02,7.010,15]he...)
Affinity DataKi:  4.09E+4nMAssay Description:Tested for invitro inhibition of the displacement of [3H]-mazindol from GABA receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma non-opioid intracellular receptor 1(RAT)
National Institute Of Diabetes And Digestive And Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50000663((+)-1-methyl-16-azatetracyclo[7.6.1.02,7.010,15]he...)
Affinity DataKi:  5.92E+4nMAssay Description:Tested for invitro inhibition of the displacement of (+)-[3H]-pentazocine from sigma opioid receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMuscarinic acetylcholine receptor M1/M2/M3/M4/M5(RAT)
National Institute Of Diabetes And Digestive And Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50000663((+)-1-methyl-16-azatetracyclo[7.6.1.02,7.010,15]he...)
Affinity DataKi: >1.00E+5nMAssay Description:Tested for in vitro inhibition of the displacement of [3H]QNB from CNS receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Rattus norvegicus (rat))
National Institute Of Diabetes And Digestive And Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50044427(1-methyl-16-azatetracyclo[7.6.1.02,7.010,15]hexade...)
Affinity DataKi: >1.00E+5nMAssay Description:Tested for invitro inhibition of the displacement of [3H]-FOXY from mu opioid receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMuscarinic acetylcholine receptor M1/M2/M3/M4/M5(RAT)
National Institute Of Diabetes And Digestive And Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50044427(1-methyl-16-azatetracyclo[7.6.1.02,7.010,15]hexade...)
Affinity DataKi: >1.00E+5nMAssay Description:Tested for in vitro inhibition of the displacement of [3H]quinuclidinyl benzilate muscarinic receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Rattus norvegicus (rat))
National Institute Of Diabetes And Digestive And Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50000663((+)-1-methyl-16-azatetracyclo[7.6.1.02,7.010,15]he...)
Affinity DataKi: >1.00E+5nMAssay Description:Tested for invitro inhibition of the displacement of [3H]-FOXY from mu opioid receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed