Compile Data Set for Download or QSAR
Report error Found 25 Enz. Inhib. hit(s) with all data for entry = 50036142
TargetKappa-type opioid receptor(Human)
Glaxo Group Research

Curated by ChEMBL
LigandPNGBDBM50027433(GR-89696 | CHEMBL603370)
Affinity DataIC50: 0.0180nMAssay Description:In vitro agonist activity at kappa opioid receptor in rabbit vas deferens.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/24/2012
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Human)
Glaxo Group Research

Curated by ChEMBL
LigandPNGBDBM50045192(4-[2-(3,4-Dichloro-phenyl)-acetyl]-3-(3,6-dihydro-...)
Affinity DataIC50: 0.0400nMAssay Description:In vitro agonist activity at kappa opioid receptor in rabbit vas deferens.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/24/2012
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Human)
Glaxo Group Research

Curated by ChEMBL
LigandPNGBDBM50027433(GR-89696 | CHEMBL603370)
Affinity DataIC50: 0.0410nMAssay Description:In vitro agonist activity at kappa opioid receptor in rabbit vas deferens.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/24/2012
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Human)
Glaxo Group Research

Curated by ChEMBL
LigandPNGBDBM50027433(GR-89696 | CHEMBL603370)
Affinity DataIC50: 0.0410nMAssay Description:In vitro agonist activity at kappa opioid receptor in rabbit vas deferens.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/24/2012
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Human)
Glaxo Group Research

Curated by ChEMBL
LigandPNGBDBM50000293(2-(3,4-Dichloro-phenyl)-1-(7-pyrrolidin-1-ylmethyl...)
Affinity DataIC50: 0.100nMAssay Description:In vitro agonist activity at kappa opioid receptor in rabbit vas deferens.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/24/2012
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Human)
Glaxo Group Research

Curated by ChEMBL
LigandPNGBDBM50045186(4-[2-(3,4-Dichloro-phenyl)-acetyl]-3-(3-methoxycar...)
Affinity DataIC50: 0.280nMAssay Description:In vitro agonist activity at kappa opioid receptor in rabbit vas deferens.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/24/2012
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Human)
Glaxo Group Research

Curated by ChEMBL
LigandPNGBDBM50045196(4-[2-(3,4-Dichloro-phenyl)-acetyl]-3-(3-hydroxy-py...)
Affinity DataIC50: 0.340nMAssay Description:In vitro agonist activity at kappa opioid receptor in rabbit vas deferens.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/24/2012
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Human)
Glaxo Group Research

Curated by ChEMBL
LigandPNGBDBM50045193(4-[2-(3,4-Dichloro-phenyl)-acetyl]-3-(3-oxo-pyrrol...)
Affinity DataIC50: 0.340nMAssay Description:In vitro agonist activity at kappa opioid receptor in rabbit vas deferens.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/24/2012
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Human)
Glaxo Group Research

Curated by ChEMBL
LigandPNGBDBM50045189(1-{4-[2-(3,4-Dichloro-phenyl)-acetyl]-3-pyrrolidin...)
Affinity DataIC50: 0.420nMAssay Description:In vitro agonist activity at kappa opioid receptor in rabbit vas deferens.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/24/2012
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Human)
Glaxo Group Research

Curated by ChEMBL
LigandPNGBDBM50045198(4-[2-(3,4-Dichloro-phenyl)-acetyl]-3-dimethylamino...)
Affinity DataIC50: 1.20nMAssay Description:In vitro agonist activity at kappa opioid receptor in rabbit vas deferens.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/24/2012
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Human)
Glaxo Group Research

Curated by ChEMBL
LigandPNGBDBM50045184(4-[2-(3,4-Dichloro-phenyl)-acetyl]-3-pyrrolidin-1-...)
Affinity DataIC50: 3.5nMAssay Description:In vitro agonist activity at kappa opioid receptor in rabbit vas deferens.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/24/2012
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Human)
Glaxo Group Research

Curated by ChEMBL
LigandPNGBDBM50045188(4-[2-(3,4-Dichloro-phenyl)-acetyl]-3-(3-methoxycar...)
Affinity DataIC50: 4nMAssay Description:In vitro agonist activity at kappa opioid receptor in rabbit vas deferens.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/24/2012
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Human)
Glaxo Group Research

Curated by ChEMBL
LigandPNGBDBM50045181(1-{4-[2-(3,4-Dichloro-phenyl)-acetyl]-3-pyrrolidin...)
Affinity DataIC50: 6.90nMAssay Description:In vitro agonist activity at kappa opioid receptor in rabbit vas deferens.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/24/2012
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Human)
Glaxo Group Research

Curated by ChEMBL
LigandPNGBDBM50045182(1-(4-Acetyl-2-pyrrolidin-1-ylmethyl-piperazin-1-yl...)
Affinity DataIC50: 10nMAssay Description:In vitro agonist activity at kappa opioid receptor in rabbit vas deferens.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/24/2012
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Human)
Glaxo Group Research

Curated by ChEMBL
LigandPNGBDBM50045183(4-[2-(3,4-Dichloro-phenyl)-acetyl]-3-pyrrolidin-1-...)
Affinity DataIC50: 15nMAssay Description:In vitro agonist activity at kappa opioid receptor in rabbit vas deferens.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/24/2012
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Human)
Glaxo Group Research

Curated by ChEMBL
LigandPNGBDBM50045187(1-{4-[2-(3,4-Dichloro-phenyl)-acetyl]-3-pyrrolidin...)
Affinity DataIC50: 60nMAssay Description:In vitro agonist activity at kappa opioid receptor in rabbit vas deferens.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/24/2012
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Human)
Glaxo Group Research

Curated by ChEMBL
LigandPNGBDBM50045199(4-[2-(3,4-Dichloro-phenyl)-acetyl]-3-pyrrolidin-1-...)
Affinity DataIC50: 300nMAssay Description:In vitro agonist activity at kappa opioid receptor in rabbit vas deferens.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/24/2012
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Human)
Glaxo Group Research

Curated by ChEMBL
LigandPNGBDBM50000296(CHEMBL441765 | CHEMBL482811 | U-50488H | US1149237...)
Affinity DataIC50: 370nMAssay Description:In vitro agonist activity at kappa opioid receptor in rabbit vas deferens.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/24/2012
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Human)
Glaxo Group Research

Curated by ChEMBL
LigandPNGBDBM50045195(4-[2-(3,4-Dichloro-phenyl)-acetyl]-3-pyrrolidin-1-...)
Affinity DataIC50: 450nMAssay Description:In vitro agonist activity at kappa opioid receptor in rabbit vas deferens.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/24/2012
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Human)
Glaxo Group Research

Curated by ChEMBL
LigandPNGBDBM50045194(2-(3,4-Dichloro-phenyl)-1-[4-(2-methoxy-acetyl)-2-...)
Affinity DataIC50: 2.90E+3nMAssay Description:In vitro agonist activity at kappa opioid receptor in rabbit vas deferens.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/24/2012
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Human)
Glaxo Group Research

Curated by ChEMBL
LigandPNGBDBM50045185(4-[2-(3,4-Dichloro-phenyl)-acetyl]-3-pyrrolidin-1-...)
Affinity DataIC50: 1.00E+4nMAssay Description:In vitro agonist activity at kappa opioid receptor in rabbit vas deferens.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/24/2012
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Human)
Glaxo Group Research

Curated by ChEMBL
LigandPNGBDBM50045197(1-(4-Benzoyl-2-pyrrolidin-1-ylmethyl-piperazin-1-y...)
Affinity DataIC50: 1.00E+4nMAssay Description:In vitro agonist activity at kappa opioid receptor in rabbit vas deferens.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/24/2012
Entry Details Article
PubMed
TargetMu-type opioid receptor(Rat)
Glaxo Group Research

Curated by ChEMBL
LigandPNGBDBM50027433(GR-89696 | CHEMBL603370)
Affinity DataIC50: 1.00E+4nMAssay Description:In vitro inhibitory activity against mu specific tissue of rat vas deferensMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/24/2012
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Human)
Glaxo Group Research

Curated by ChEMBL
LigandPNGBDBM50027433(GR-89696 | CHEMBL603370)
Affinity DataIC50: 1.00E+4nMAssay Description:In vitro inhibitory activity against delta specific tissue of hamster vas deferensMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/24/2012
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Human)
Glaxo Group Research

Curated by ChEMBL
LigandPNGBDBM50045191(2-(3,4-Dichloro-phenyl)-1-(4-phenylacetyl-2-pyrrol...)
Affinity DataIC50: 1.00E+4nMAssay Description:In vitro agonist activity at kappa opioid receptor in rabbit vas deferens.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/24/2012
Entry Details Article
PubMed