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Found 25 Enz. Inhib. hit(s) with all data for entry = 50006446
TargetSqualene synthase(Rattus norvegicus)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50031845((4-Biphenyl-4-yl-1-phosphono-butyl)-phosphonic aci...)
Affinity DataIC50:  0.700nMAssay Description:Inhibitory activity against rat liver microsomal squalene synthase was determined using [3H]-FPP as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSqualene synthase(Rattus norvegicus)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50049232(CHEMBL348349 | Tetrasodium salt of 4-(4'-Methyl-bi...)
Affinity DataIC50:  1nMAssay Description:Inhibitory activity against rat liver microsomal squalene synthase was determined using [3H]-FPP as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSqualene synthase(Rattus norvegicus)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50049227(CHEMBL158707 | Trisodium salt of [1-(Dimethoxy-pho...)
Affinity DataIC50:  5.70nMAssay Description:Inhibitory activity against rat liver microsomal squalene synthase was determined using [3H]-FPP as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSqualene synthase(Rattus norvegicus)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50049217(CHEMBL158517 | Tripotassium salt of 1-Phosphono-4-...)
Affinity DataIC50:  13nMAssay Description:Inhibitory activity against rat liver microsomal squalene synthase was determined using [3H]-FPP as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSqualene synthase(Rattus norvegicus)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50049233(CHEMBL160240 | Tripotassium salt of 4-Biphenyl-4-y...)
Affinity DataIC50:  15nMAssay Description:Inhibitory activity against rat liver microsomal squalene synthase was determined using [3H]-FPP as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSqualene synthase(Rattus norvegicus)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50049230(CHEMBL160267 | Tripotassium salt of 4-{3-[2-(4-Met...)
Affinity DataIC50:  17nMAssay Description:Inhibitory activity against rat liver microsomal squalene synthase was determined using [3H]-FPP as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSqualene synthase(Rattus norvegicus)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50049215(1-Phosphono-4-[3-(2-benzylphenoxy)phenyl]butylsulf...)
Affinity DataIC50:  18nMAssay Description:Inhibitory activity against rat liver microsomal squalene synthase was determined using [3H]-FPP as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSqualene synthase(Rattus norvegicus)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50049228(CHEMBL158448 | Tripotassium salt of 4-{3-[2-(3-Met...)
Affinity DataIC50:  19nMAssay Description:Inhibitory activity against rat liver microsomal squalene synthase was determined using [3H]-FPP as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSqualene synthase(Rattus norvegicus)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50049223(CHEMBL158851 | Tripotassium salt of4-[3-(2-Butyl-p...)
Affinity DataIC50:  35nMAssay Description:Inhibitory activity against rat liver microsomal squalene synthase was determined using [3H]-FPP as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSqualene synthase(Rattus norvegicus)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50049224(CHEMBL158862 | Tripotassium salt of 1-Phosphono-4-...)
Affinity DataIC50:  35nMAssay Description:Inhibitory activity against rat liver microsomal squalene synthase was determined using [3H]-FPP as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSqualene synthase(Rattus norvegicus)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50049221(CHEMBL158978 | Tripotassium salt of 4-(4'-But-1-en...)
Affinity DataIC50:  76nMAssay Description:Inhibitory activity against rat liver microsomal squalene synthase was determined using [3H]-FPP as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSqualene synthase(Rattus norvegicus)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50049225(CHEMBL351866 | Tripotassium salt of 4-(4'-Propyl-b...)
Affinity DataIC50:  144nMAssay Description:Inhibitory activity against rat liver microsomal squalene synthase was determined using [3H]-FPP as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSqualene synthase(Rattus norvegicus)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50049236((+/-)-1-Phosphono-4-(3-phenoxyphenyl)butylsulfonic...)
Affinity DataIC50:  169nMAssay Description:Inhibitory activity against rat liver microsomal squalene synthase was determined using [3H]-FPP as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSqualene synthase(Rattus norvegicus)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50049229(1-Phosphono-4-[4-(4-butylphenyl)phenyl]butylsulfon...)
Affinity DataIC50:  192nMAssay Description:Inhibitory activity against rat liver microsomal squalene synthase was determined using [3H]-FPP as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSqualene synthase(Rattus norvegicus)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50049226(CHEMBL158527 | Tripotassium salt of 1-Phosphono-4-...)
Affinity DataIC50:  200nMAssay Description:Inhibitory activity against rat liver microsomal squalene synthase was determined using [3H]-FPP as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSqualene synthase(Rattus norvegicus)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50049220(CHEMBL346762 | Tripotassium salt of 1-Phosphono-4-...)
Affinity DataIC50:  268nMAssay Description:Inhibitory activity against rat liver microsomal squalene synthase was determined using [3H]-FPP as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSqualene synthase(Rattus norvegicus)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50049218(CHEMBL159021 | Tripotassium salt of 4-[3-(2-Phenox...)
Affinity DataIC50:  286nMAssay Description:Inhibitory activity against rat liver microsomal squalene synthase was determined using [3H]-FPP as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSqualene synthase(Rattus norvegicus)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50049238(CHEMBL158154 | trisodium (5E)-6,10-dimethyl-1-phos...)
Affinity DataIC50:  740nMAssay Description:Inhibitory activity against rat liver microsomal squalene synthase was determined using [3H]-FPP as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSqualene synthase(Rattus norvegicus)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50049231(CHEMBL347175 | CHEMBL513790 | Trisodium salt of 4-...)
Affinity DataIC50:  1.98E+3nMAssay Description:Inhibitory activity against rat liver microsomal squalene synthase was determined using [3H]-FPP as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSqualene synthase(Rattus norvegicus)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50049216(CHEMBL160796 | Tripotassium salt of 4-(4'-Ethyl-bi...)
Affinity DataIC50:  2.00E+3nMAssay Description:Inhibitory activity against rat liver microsomal squalene synthase was determined using [3H]-FPP as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSqualene synthase(Rattus norvegicus)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50049219(1-Phosphono-4-[4-(4-methylphenyl)phenyl]butylsulfo...)
Affinity DataIC50:  4.60E+3nMAssay Description:Inhibitory activity against rat liver microsomal squalene synthase was determined using [3H]-FPP as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSqualene synthase(Rattus norvegicus)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50049235(CHEMBL158931 | Tripotassium salt of 4-(4'-Pentyl-b...)
Affinity DataIC50:  6.20E+3nMAssay Description:Inhibitory activity against rat liver microsomal squalene synthase was determined using [3H]-FPP as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSqualene synthase(Rattus norvegicus)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50049234(CHEMBL158667 | Tripotassium salt of 1-Phosphono-4-...)
Affinity DataIC50:  6.90E+3nMAssay Description:Inhibitory activity against rat liver microsomal squalene synthase was determined using [3H]-FPP as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSqualene synthase(Rattus norvegicus)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50049237(CHEMBL347856 | Tripotassium salt of 1-Phosphono-4-...)
Affinity DataIC50:  8.20E+3nMAssay Description:Inhibitory activity against rat liver microsomal squalene synthase was determined using [3H]-FPP as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSqualene synthase(Rattus norvegicus)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50049222(1-Phosphono-4-[3-(4-propylphenoxy)phenyl]butylsulf...)
Affinity DataIC50:  1.42E+4nMAssay Description:Inhibitory activity against rat liver microsomal squalene synthase was determined using [3H]-FPP as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed