Compile Data Set for Download or QSAR
maximum 50k data
Found 30 Enz. Inhib. hit(s) with all data for entry = 1210
TargetAromatase(Homo sapiens (Human))
Centre De Recherche De Roussel Uclaf

LigandPNGBDBM10045((2R,15S)-15-methyl-2-[2-(methylsulfanyl)ethyl]tetr...)
Affinity DataIC50:  12nMpH: 7.2 T: 2°CAssay Description:The enzyme activity was assayed by measuring the formation of tritiated water from [1beta, 2beta-3H ]androstenedione in the presence of increasing co...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAromatase(Homo sapiens (Human))
Centre De Recherche De Roussel Uclaf

LigandPNGBDBM10046((2S,15S)-15-methyl-2-[2-(methylsulfanyl)ethyl]tetr...)
Affinity DataIC50:  22nMpH: 7.2 T: 2°CAssay Description:The enzyme activity was assayed by measuring the formation of tritiated water from [1beta, 2beta-3H ]androstenedione in the presence of increasing co...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAromatase(Homo sapiens (Human))
Centre De Recherche De Roussel Uclaf

LigandPNGBDBM10044((2S,15S)-15-methyl-2-[(methylsulfanyl)methyl]tetra...)
Affinity DataIC50:  42nMpH: 7.2 T: 2°CAssay Description:The enzyme activity was assayed by measuring the formation of tritiated water from [1beta, 2beta-3H ]androstenedione in the presence of increasing co...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAromatase(Homo sapiens (Human))
Centre De Recherche De Roussel Uclaf

LigandPNGBDBM10069((2R,15S)-2-{2-[(fluoromethyl)sulfanyl]ethyl}-15-me...)
Affinity DataIC50:  50nMAssay Description:The enzyme activity was assayed by measuring the formation of tritiated water from [1beta, 2beta-3H ]androstenedione in the presence of increasing co...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAromatase(Homo sapiens (Human))
Centre De Recherche De Roussel Uclaf

LigandPNGBDBM10064((2R,15S)-2-[2-(ethenylsulfanyl)ethyl]-15-methyltet...)
Affinity DataIC50:  50nMAssay Description:The enzyme activity was assayed by measuring the formation of tritiated water from [1beta, 2beta-3H ]androstenedione in the presence of increasing co...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAromatase(Homo sapiens (Human))
Centre De Recherche De Roussel Uclaf

LigandPNGBDBM10063((2R,15S)-15-methyl-2-[2-(prop-2-en-1-ylsulfanyl)et...)
Affinity DataIC50:  270nMAssay Description:The enzyme activity was assayed by measuring the formation of tritiated water from [1beta, 2beta-3H ]androstenedione in the presence of increasing co...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAromatase(Homo sapiens (Human))
Centre De Recherche De Roussel Uclaf

LigandPNGBDBM10068((2R,15S)-2-[2-(ethynylsulfanyl)ethyl]-15-methyltet...)
Affinity DataIC50:  330nMAssay Description:The enzyme activity was assayed by measuring the formation of tritiated water from [1beta, 2beta-3H ]androstenedione in the presence of increasing co...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAromatase(Homo sapiens (Human))
Centre De Recherche De Roussel Uclaf

LigandPNGBDBM10054((2R,15S)-15-methyl-2-[2-(phenylsulfanyl)ethyl]tetr...)
Affinity DataIC50:  400nMpH: 7.2 T: 2°CAssay Description:The enzyme activity was assayed by measuring the formation of tritiated water from [1beta, 2beta-3H ]androstenedione in the presence of increasing co...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAromatase(Homo sapiens (Human))
Centre De Recherche De Roussel Uclaf

LigandPNGBDBM10062((2R,15S)-15-methyl-2-(2-{[(methylsulfanyl)methyl]s...)
Affinity DataIC50:  570nMAssay Description:The enzyme activity was assayed by measuring the formation of tritiated water from [1beta, 2beta-3H ]androstenedione in the presence of increasing co...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAromatase(Homo sapiens (Human))
Centre De Recherche De Roussel Uclaf

LigandPNGBDBM10047((2R,15S)-2-[2-(ethylsulfanyl)ethyl]-15-methyltetra...)
Affinity DataIC50:  870nMpH: 7.2 T: 2°CAssay Description:The enzyme activity was assayed by measuring the formation of tritiated water from [1beta, 2beta-3H ]androstenedione in the presence of increasing co...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAromatase(Homo sapiens (Human))
Centre De Recherche De Roussel Uclaf

LigandPNGBDBM10053((2R,15S)-15-methyl-2-[2-(phenylselanyl)ethyl]tetra...)
Affinity DataIC50: >1.00E+3nMpH: 7.2 T: 2°CAssay Description:The enzyme activity was assayed by measuring the formation of tritiated water from [1beta, 2beta-3H ]androstenedione in the presence of increasing co...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAromatase(Homo sapiens (Human))
Centre De Recherche De Roussel Uclaf

LigandPNGBDBM10057((2R,15S)-2-{2-[(2-chloroethyl)sulfanyl]ethyl}-15-m...)
Affinity DataIC50: >1.00E+3nMpH: 7.2 T: 2°CAssay Description:The enzyme activity was assayed by measuring the formation of tritiated water from [1beta, 2beta-3H ]androstenedione in the presence of increasing co...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAromatase(Homo sapiens (Human))
Centre De Recherche De Roussel Uclaf

LigandPNGBDBM10071((2R,15S)-2-[2,2-bis(methylsulfanyl)ethyl]-15-methy...)
Affinity DataIC50: >1.00E+3nMAssay Description:The enzyme activity was assayed by measuring the formation of tritiated water from [1beta, 2beta-3H ]androstenedione in the presence of increasing co...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAromatase(Homo sapiens (Human))
Centre De Recherche De Roussel Uclaf

LigandPNGBDBM10070(({2-[(2R,15S)-15-methyl-5,14-dioxotetracyclo[8.7.0...)
Affinity DataIC50: >1.00E+3nMAssay Description:The enzyme activity was assayed by measuring the formation of tritiated water from [1beta, 2beta-3H ]androstenedione in the presence of increasing co...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAromatase(Homo sapiens (Human))
Centre De Recherche De Roussel Uclaf

LigandPNGBDBM10067((2R,15S)-2-[2-(cyclopropylsulfanyl)ethyl]-15-methy...)
Affinity DataIC50: >1.00E+3nMAssay Description:The enzyme activity was assayed by measuring the formation of tritiated water from [1beta, 2beta-3H ]androstenedione in the presence of increasing co...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAromatase(Homo sapiens (Human))
Centre De Recherche De Roussel Uclaf

LigandPNGBDBM10066((2R,15S)-15-methyl-2-[2-(phenyldisulfanyl)ethyl]te...)
Affinity DataIC50: >1.00E+3nMAssay Description:The enzyme activity was assayed by measuring the formation of tritiated water from [1beta, 2beta-3H ]androstenedione in the presence of increasing co...More data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails ArticlePubMed
TargetAromatase(Homo sapiens (Human))
Centre De Recherche De Roussel Uclaf

LigandPNGBDBM10065((2R,15S)-15-methyl-2-[2-(methyldisulfanyl)ethyl]te...)
Affinity DataIC50: >1.00E+3nMAssay Description:The enzyme activity was assayed by measuring the formation of tritiated water from [1beta, 2beta-3H ]androstenedione in the presence of increasing co...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAromatase(Homo sapiens (Human))
Centre De Recherche De Roussel Uclaf

LigandPNGBDBM10061((2R,15S)-15-methyl-2-[2-(prop-2-yn-1-ylsulfanyl)et...)
Affinity DataIC50:  1.00E+3nMAssay Description:The enzyme activity was assayed by measuring the formation of tritiated water from [1beta, 2beta-3H ]androstenedione in the presence of increasing co...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAromatase(Homo sapiens (Human))
Centre De Recherche De Roussel Uclaf

LigandPNGBDBM10056((2R,15S)-2-{2-[(2-hydroxyethyl)sulfanyl]ethyl}-15-...)
Affinity DataIC50: >1.00E+3nMpH: 7.2 T: 2°CAssay Description:The enzyme activity was assayed by measuring the formation of tritiated water from [1beta, 2beta-3H ]androstenedione in the presence of increasing co...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAromatase(Homo sapiens (Human))
Centre De Recherche De Roussel Uclaf

LigandPNGBDBM10072((2R,15S)-2-[2,2-bis(ethylsulfanyl)ethyl]-15-methyl...)
Affinity DataIC50: >1.00E+3nMAssay Description:The enzyme activity was assayed by measuring the formation of tritiated water from [1beta, 2beta-3H ]androstenedione in the presence of increasing co...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAromatase(Homo sapiens (Human))
Centre De Recherche De Roussel Uclaf

LigandPNGBDBM10058((2R,15S)-15-methyl-2-{2-[(2-sulfanylethyl)sulfanyl...)
Affinity DataIC50: >1.00E+3nMpH: 7.2 T: 2°CAssay Description:The enzyme activity was assayed by measuring the formation of tritiated water from [1beta, 2beta-3H ]androstenedione in the presence of increasing co...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAromatase(Homo sapiens (Human))
Centre De Recherche De Roussel Uclaf

LigandPNGBDBM10059((2R,15S)-2-{2-[(difluoromethyl)sulfanyl]ethyl}-15-...)
Affinity DataIC50: >1.00E+3nMAssay Description:The enzyme activity was assayed by measuring the formation of tritiated water from [1beta, 2beta-3H ]androstenedione in the presence of increasing co...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAromatase(Homo sapiens (Human))
Centre De Recherche De Roussel Uclaf

LigandPNGBDBM10060((2R,15S)-2-{2-[(2,4-dinitrophenyl)disulfanyl]ethyl...)
Affinity DataIC50: >1.00E+3nMAssay Description:The enzyme activity was assayed by measuring the formation of tritiated water from [1beta, 2beta-3H ]androstenedione in the presence of increasing co...More data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails ArticlePubMed
TargetAromatase(Homo sapiens (Human))
Centre De Recherche De Roussel Uclaf

LigandPNGBDBM10043((2R,15S)-15-methyl-2-(methylsulfanyl)tetracyclo[8....)
Affinity DataIC50:  7.40E+3nMpH: 7.2 T: 2°CAssay Description:The enzyme activity was assayed by measuring the formation of tritiated water from [1beta, 2beta-3H ]androstenedione in the presence of increasing co...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAromatase(Homo sapiens (Human))
Centre De Recherche De Roussel Uclaf

LigandPNGBDBM10049((2R,15S)-2-[2-(dimethylamino)ethyl]-15-methyltetra...)
Affinity DataIC50: >1.00E+4nMpH: 7.2 T: 2°CAssay Description:The enzyme activity was assayed by measuring the formation of tritiated water from [1beta, 2beta-3H ]androstenedione in the presence of increasing co...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAromatase(Homo sapiens (Human))
Centre De Recherche De Roussel Uclaf

LigandPNGBDBM10050((2R,15S)-2-(2-methoxyethyl)-15-methyltetracyclo[8....)
Affinity DataIC50:  1.00E+4nMpH: 7.2 T: 2°CAssay Description:The enzyme activity was assayed by measuring the formation of tritiated water from [1beta, 2beta-3H ]androstenedione in the presence of increasing co...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAromatase(Homo sapiens (Human))
Centre De Recherche De Roussel Uclaf

LigandPNGBDBM10051((2R,15S)-2-(2-iodoethyl)-15-methyltetracyclo[8.7.0...)
Affinity DataIC50: >1.00E+4nMpH: 7.2 T: 2°CAssay Description:The enzyme activity was assayed by measuring the formation of tritiated water from [1beta, 2beta-3H ]androstenedione in the presence of increasing co...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAromatase(Homo sapiens (Human))
Centre De Recherche De Roussel Uclaf

LigandPNGBDBM10048((2R,15S)-15-methyl-2-[3-(methylsulfanyl)propyl]tet...)
Affinity DataIC50: >1.00E+4nMpH: 7.2 T: 2°CAssay Description:The enzyme activity was assayed by measuring the formation of tritiated water from [1beta, 2beta-3H ]androstenedione in the presence of increasing co...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAromatase(Homo sapiens (Human))
Centre De Recherche De Roussel Uclaf

LigandPNGBDBM10055((2R,15S)-2-[2-(acetylsulfanyl)ethyl]-15-methyltetr...)
Affinity DataIC50: >1.00E+4nMpH: 7.2 T: 2°CAssay Description:The enzyme activity was assayed by measuring the formation of tritiated water from [1beta, 2beta-3H ]androstenedione in the presence of increasing co...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAromatase(Homo sapiens (Human))
Centre De Recherche De Roussel Uclaf

LigandPNGBDBM10052(19-Heteromethyl-Substituted Androstenedione Analog...)
Affinity DataIC50: >1.00E+4nMpH: 7.2 T: 2°CAssay Description:The enzyme activity was assayed by measuring the formation of tritiated water from [1beta, 2beta-3H ]androstenedione in the presence of increasing co...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed