Compile Data Set for Download or QSAR
Report error Found 11 Enz. Inhib. hit(s) with all data for entry = 50006530
TargetCannabinoid receptor 1(Rat)
National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50009854(CHEMBL13078 | [1-(2-Morpholin-4-yl-ethyl)-1H-indol...)
Affinity DataIC50: 46nMAssay Description:Binding affinity against brain cannabinoid receptor 1 using [3H]CP-55940 as radioligand at 0.25 nM concentrationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCannabinoid receptor 1(Rat)
National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50009864(CHEMBL274833 | [2-Methyl-1-(2-morpholin-4-yl-ethyl...)
Affinity DataIC50: 73nMAssay Description:Binding affinity against brain Cannabinoid receptor 1 using [3H]CP-55940 as radioligand at 1.1 nM concentrationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCannabinoid receptor 1(Rat)
National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50050489([6-Isothiocyanato-1-(2-morpholin-4-yl-ethyl)-1H-in...)
Affinity DataIC50: 160nMAssay Description:Binding affinity against brain cannabinoid receptor 1 using [3H]CP-55940 as radioligand at 0.25 nM concentrationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAdenylate cyclase type 5(Rat)
National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50009854(CHEMBL13078 | [1-(2-Morpholin-4-yl-ethyl)-1H-indol...)
Affinity DataEC50:  275nMAssay Description:Compound was evaluated for inhibition of hormone stimulated Adenylate cyclase activity in N18TG2 membranes.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAdenylate cyclase type 5(Rat)
National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50009864(CHEMBL274833 | [2-Methyl-1-(2-morpholin-4-yl-ethyl...)
Affinity DataEC50:  370nMAssay Description:Compound was evaluated for inhibition of hormone stimulated Adenylate cyclase activity in N18TG2 membranes.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCannabinoid receptor 1(Rat)
National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50050492((4-Isothiocyanato-naphthalen-1-yl)-[1-(2-morpholin...)
Affinity DataIC50: 440nMAssay Description:Binding affinity against brain cannabinoid receptor 1 using [3H]CP-55940 as radioligand at 0.25 nM concentrationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCannabinoid receptor 1(Rat)
National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50050490((6-Isothiocyanato-naphthalen-1-yl)-[1-(2-morpholin...)
Affinity DataIC50: 530nMAssay Description:Binding affinity against brain cannabinoid receptor 1 using [3H]CP-55940 as radioligand at 0.25 nM concentrationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCannabinoid receptor 1(Rat)
National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50050491((4-Isothiocyanato-naphthalen-1-yl)-[2-methyl-1-(2-...)
Affinity DataIC50: 690nMAssay Description:Binding affinity against brain Cannabinoid receptor 1 using [3H]CP-55940 as radioligand at 1.1 nM concentrationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCannabinoid receptor 1(Rat)
National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50050488((3-Isothiocyanato-naphthalen-1-yl)-[1-(2-morpholin...)
Affinity DataIC50: 920nMAssay Description:Binding affinity against brain cannabinoid receptor 1 using [3H]CP-55940 as radioligand at 0.25 nM concentrationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAdenylate cyclase type 5(Rat)
National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50050489([6-Isothiocyanato-1-(2-morpholin-4-yl-ethyl)-1H-in...)
Affinity DataEC50:  1.10E+3nMAssay Description:Compound was evaluated for inhibition of hormone stimulated Adenylate cyclase activity in N18TG2 membranes.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAdenylate cyclase type 5(Rat)
National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50050491((4-Isothiocyanato-naphthalen-1-yl)-[2-methyl-1-(2-...)
Affinity DataEC50:  3.00E+3nMAssay Description:Compound was evaluated for inhibition of hormone stimulated Adenylate cyclase activity in N18TG2 membranes.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed