Compile Data Set for Download or QSAR
maximum 50k data
Found 50 Enz. Inhib. hit(s) with all data for entry = 50006558
TargetEndothelin-1 receptor(Homo sapiens (Human))
Basf

Curated by ChEMBL
LigandPNGBDBM50050807(3-Methoxy-2-(4-methoxy-6-methyl-pyrimidin-2-yloxy)...)
Affinity DataKi:  0.120nMAssay Description:Binding affinity of the compound towards human Endothelin A receptor by measuring its ability to displace [125I]-ET-1 from CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin-1 receptor(Homo sapiens (Human))
Basf

Curated by ChEMBL
LigandPNGBDBM50050793(3-Methoxy-2-(4-methoxy-6,7-dihydro-5H-cyclopentapy...)
Affinity DataKi:  0.400nMAssay Description:Binding affinity of the compound towards human Endothelin A receptor by measuring its ability to displace [125I]-ET-1 from CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin-1 receptor(Homo sapiens (Human))
Basf

Curated by ChEMBL
LigandPNGBDBM50050789(2-(4-Ethyl-6-methyl-pyrimidin-2-yloxy)-3-methoxy-3...)
Affinity DataKi:  0.700nMAssay Description:Binding affinity of the compound towards human Endothelin A receptor by measuring its ability to displace [125I]-ET-1 from CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin-1 receptor(Homo sapiens (Human))
Basf

Curated by ChEMBL
LigandPNGBDBM50050800(3-Methoxy-2-(4-methoxy-5,6-dihydro-furo[2,3-d]pyri...)
Affinity DataKi:  0.900nMAssay Description:Binding affinity of the compound towards human Endothelin A receptor by measuring its ability to displace [125I]-ET-1 from CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin-1 receptor(Homo sapiens (Human))
Basf

Curated by ChEMBL
LigandPNGBDBM50050806(2-(4,6-Dimethyl-pyrimidin-2-yloxy)-3-methoxy-3,3-d...)
Affinity DataKi:  1nMAssay Description:Binding affinity of the compound towards human Endothelin A receptor by measuring its ability to displace [125I]-ET-1 from CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin-1 receptor(Homo sapiens (Human))
Basf

Curated by ChEMBL
LigandPNGBDBM50050796(2-(4,6-Diethyl-pyrimidin-2-yloxy)-3-methoxy-3,3-di...)
Affinity DataKi:  1nMAssay Description:Binding affinity of the compound towards human Endothelin A receptor by measuring its ability to displace [125I]-ET-1 from CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin-1 receptor(Homo sapiens (Human))
Basf

Curated by ChEMBL
LigandPNGBDBM50050794(2-(4,6-Dimethoxy-pyrimidin-2-yloxy)-3-methoxy-3,3-...)
Affinity DataKi:  6nMAssay Description:Binding affinity of the compound towards human Endothelin A receptor by measuring its ability to displace [125I]-ET-1 from CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin-1 receptor(Homo sapiens (Human))
Basf

Curated by ChEMBL
LigandPNGBDBM50050802(2-(4,6-Dimethoxy-pyrimidin-2-yloxy)-3-ethoxy-3,3-d...)
Affinity DataKi:  7nMAssay Description:Binding affinity of the compound towards human Endothelin A receptor by measuring its ability to displace [125I]-ET-1 from CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin-1 receptor(Homo sapiens (Human))
Basf

Curated by ChEMBL
LigandPNGBDBM50050790(2-(4,6-Dimethoxy-pyrimidin-2-yloxy)-3,3-bis-(3-flu...)
Affinity DataKi:  11nMAssay Description:Binding affinity of the compound towards human Endothelin A receptor by measuring its ability to displace [125I]-ET-1 from CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin-1 receptor(Homo sapiens (Human))
Basf

Curated by ChEMBL
LigandPNGBDBM50050795(2-(4,6-Dimethoxy-pyrimidin-2-yloxy)-3,3-diphenyl-3...)
Affinity DataKi:  19nMAssay Description:Binding affinity of the compound towards human Endothelin A receptor by measuring its ability to displace [125I]-ET-1 from CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin-1 receptor(Homo sapiens (Human))
Basf

Curated by ChEMBL
LigandPNGBDBM50050810(3-Methoxy-2-(4-methyl-pyrimidin-2-yloxy)-3,3-diphe...)
Affinity DataKi:  19nMAssay Description:Binding affinity of the compound towards human Endothelin A receptor by measuring its ability to displace [125I]-ET-1 from CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin receptor type B(Homo sapiens (Human))
Basf

Curated by ChEMBL
LigandPNGBDBM50050807(3-Methoxy-2-(4-methoxy-6-methyl-pyrimidin-2-yloxy)...)
Affinity DataKi:  20nMAssay Description:Binding affinity of the compound towards human Endothelin B receptor by measuring its ability to displace [125I]-ET-3 from CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin receptor type B(Homo sapiens (Human))
Basf

Curated by ChEMBL
LigandPNGBDBM50050793(3-Methoxy-2-(4-methoxy-6,7-dihydro-5H-cyclopentapy...)
Affinity DataKi:  20.4nMAssay Description:Binding affinity of the compound towards human Endothelin B receptor by measuring its ability to displace [125I]-ET-3 from CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin-1 receptor(Homo sapiens (Human))
Basf

Curated by ChEMBL
LigandPNGBDBM50050788(2-(4,6-Dimethoxy-pyrimidin-2-yloxy)-3-methoxy-3,3-...)
Affinity DataKi:  22nMAssay Description:Binding affinity of the compound towards human Endothelin A receptor by measuring its ability to displace [125I]-ET-1 from CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin-1 receptor(Homo sapiens (Human))
Basf

Curated by ChEMBL
LigandPNGBDBM50050805(2-(4,6-Dimethoxy-pyrimidin-2-yloxy)-3-methoxy-3,3-...)
Affinity DataKi:  24nMAssay Description:Binding affinity of the compound towards human Endothelin A receptor by measuring its ability to displace [125I]-ET-1 from CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin receptor type B(Homo sapiens (Human))
Basf

Curated by ChEMBL
LigandPNGBDBM50050800(3-Methoxy-2-(4-methoxy-5,6-dihydro-furo[2,3-d]pyri...)
Affinity DataKi:  25nMAssay Description:Binding affinity of the compound towards human Endothelin B receptor by measuring its ability to displace [125I]-ET-3 from CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin receptor type B(Homo sapiens (Human))
Basf

Curated by ChEMBL
LigandPNGBDBM50050807(3-Methoxy-2-(4-methoxy-6-methyl-pyrimidin-2-yloxy)...)
Affinity DataKi:  29nMAssay Description:Binding affinity of the compound towards Endothelin B receptor by measuring its ability to displace [125I]-ET-3 from guinea pig cerebellumMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin-1 receptor(Homo sapiens (Human))
Basf

Curated by ChEMBL
LigandPNGBDBM50050797(2-(4,6-Dimethoxy-pyrimidin-2-yloxy)-3,3-bis-(4-flu...)
Affinity DataKi:  33nMAssay Description:Binding affinity of the compound towards human Endothelin A receptor by measuring its ability to displace [125I]-ET-1 from CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin receptor type B(Homo sapiens (Human))
Basf

Curated by ChEMBL
LigandPNGBDBM50050793(3-Methoxy-2-(4-methoxy-6,7-dihydro-5H-cyclopentapy...)
Affinity DataKi:  56nMAssay Description:Binding affinity of the compound towards Endothelin B receptor by measuring its ability to displace [125I]-ET-3 from guinea pig cerebellumMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin receptor type B(Homo sapiens (Human))
Basf

Curated by ChEMBL
LigandPNGBDBM50050800(3-Methoxy-2-(4-methoxy-5,6-dihydro-furo[2,3-d]pyri...)
Affinity DataKi:  57nMAssay Description:Binding affinity of the compound towards human Endothelin B receptor by measuring its ability to displace [125I]-ET-3 from guinea pig cerebellumMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin-1 receptor(Homo sapiens (Human))
Basf

Curated by ChEMBL
LigandPNGBDBM50050792(2-(4,6-Dimethoxy-pyrimidin-2-yloxy)-3-phenoxy-3,3-...)
Affinity DataKi:  86nMAssay Description:Binding affinity of the compound towards human Endothelin A receptor by measuring its ability to displace [125I]-ET-1 from CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin-1 receptor(Homo sapiens (Human))
Basf

Curated by ChEMBL
LigandPNGBDBM50050803(2-(4,6-Dimethoxy-pyrimidin-2-yloxy)-3-hydroxy-3,3-...)
Affinity DataKi:  130nMAssay Description:Binding affinity of the compound towards human Endothelin A receptor by measuring its ability to displace [125I]-ET-1 from CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin-1 receptor(Homo sapiens (Human))
Basf

Curated by ChEMBL
LigandPNGBDBM50050808(2-(4,6-Dimethoxy-pyrimidin-2-yloxy)-3,3-bis-(2-flu...)
Affinity DataKi:  150nMAssay Description:Binding affinity of the compound towards human Endothelin A receptor by measuring its ability to displace [125I]-ET-1 from CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin-1 receptor(Homo sapiens (Human))
Basf

Curated by ChEMBL
LigandPNGBDBM50050798(2-(4,6-Dimethoxy-pyrimidin-2-yloxy)-3-(4-methylsul...)
Affinity DataKi:  160nMAssay Description:Binding affinity of the compound towards human Endothelin A receptor by measuring its ability to displace [125I]-ET-1 from CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin receptor type B(Homo sapiens (Human))
Basf

Curated by ChEMBL
LigandPNGBDBM50050789(2-(4-Ethyl-6-methyl-pyrimidin-2-yloxy)-3-methoxy-3...)
Affinity DataKi:  160nMAssay Description:Binding affinity of the compound towards human Endothelin B receptor by measuring its ability to displace [125I]-ET-3 from guinea pig cerebellumMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin-1 receptor(Homo sapiens (Human))
Basf

Curated by ChEMBL
LigandPNGBDBM50050801(2-(4,6-Diethoxy-pyrimidin-2-yloxy)-3-methoxy-3,3-d...)
Affinity DataKi:  174nMAssay Description:Binding affinity of the compound towards human Endothelin A receptor by measuring its ability to displace [125I]-ET-1 from CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin receptor type B(Homo sapiens (Human))
Basf

Curated by ChEMBL
LigandPNGBDBM50050806(2-(4,6-Dimethyl-pyrimidin-2-yloxy)-3-methoxy-3,3-d...)
Affinity DataKi:  195nMAssay Description:Binding affinity of the compound towards human Endothelin B receptor by measuring its ability to displace [125I]-ET-3 from guinea pig cerebellumMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin-1 receptor(Homo sapiens (Human))
Basf

Curated by ChEMBL
LigandPNGBDBM50050791(2-(4,6-Dimethoxy-pyrimidin-2-yloxy)-3-methoxy-3,3-...)
Affinity DataKi:  200nMAssay Description:Binding affinity of the compound towards human Endothelin A receptor by measuring its ability to displace [125I]-ET-1 from CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin-1 receptor(Homo sapiens (Human))
Basf

Curated by ChEMBL
LigandPNGBDBM50050799(3,3-Bis-(4-chloro-phenyl)-2-(4,6-dimethoxy-pyrimid...)
Affinity DataKi:  245nMAssay Description:Binding affinity of the compound towards human Endothelin A receptor by measuring its ability to displace [125I]-ET-1 from CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin-1 receptor(Homo sapiens (Human))
Basf

Curated by ChEMBL
LigandPNGBDBM50050809(2-(4,6-Dimethoxy-pyrimidin-2-yloxy)-3-(4-isopropyl...)
Affinity DataKi:  250nMAssay Description:Binding affinity of the compound towards human Endothelin A receptor by measuring its ability to displace [125I]-ET-1 from CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin-1 receptor(Homo sapiens (Human))
Basf

Curated by ChEMBL
LigandPNGBDBM50050804(2-(4,6-Dimethoxy-pyrimidin-2-yloxy)-3-(3,3-dimethy...)
Affinity DataKi:  340nMAssay Description:Binding affinity of the compound towards human Endothelin A receptor by measuring its ability to displace [125I]-ET-1 from CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin receptor type B(Homo sapiens (Human))
Basf

Curated by ChEMBL
LigandPNGBDBM50050794(2-(4,6-Dimethoxy-pyrimidin-2-yloxy)-3-methoxy-3,3-...)
Affinity DataKi:  371nMAssay Description:Binding affinity of the compound towards human Endothelin B receptor by measuring its ability to displace [125I]-ET-3 from CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin receptor type B(Homo sapiens (Human))
Basf

Curated by ChEMBL
LigandPNGBDBM50050797(2-(4,6-Dimethoxy-pyrimidin-2-yloxy)-3,3-bis-(4-flu...)
Affinity DataKi:  970nMAssay Description:Binding affinity of the compound towards human Endothelin B receptor by measuring its ability to displace [125I]-ET-3 from guinea pig cerebellumMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin receptor type B(Homo sapiens (Human))
Basf

Curated by ChEMBL
LigandPNGBDBM50050794(2-(4,6-Dimethoxy-pyrimidin-2-yloxy)-3-methoxy-3,3-...)
Affinity DataKi:  1.00E+3nMAssay Description:Binding affinity of the compound towards human Endothelin B receptor by measuring its ability to displace [125I]-ET-3 from guinea pig cerebellumMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin receptor type B(Homo sapiens (Human))
Basf

Curated by ChEMBL
LigandPNGBDBM50050791(2-(4,6-Dimethoxy-pyrimidin-2-yloxy)-3-methoxy-3,3-...)
Affinity DataKi:  1.00E+3nMAssay Description:Binding affinity of the compound towards human Endothelin B receptor by measuring its ability to displace [125I]-ET-3 from guinea pig cerebellumMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin receptor type B(Homo sapiens (Human))
Basf

Curated by ChEMBL
LigandPNGBDBM50050796(2-(4,6-Diethyl-pyrimidin-2-yloxy)-3-methoxy-3,3-di...)
Affinity DataKi:  1.10E+3nMAssay Description:Binding affinity of the compound towards human Endothelin B receptor by measuring its ability to displace [125I]-ET-3 from guinea pig cerebellumMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin receptor type B(Homo sapiens (Human))
Basf

Curated by ChEMBL
LigandPNGBDBM50050799(3,3-Bis-(4-chloro-phenyl)-2-(4,6-dimethoxy-pyrimid...)
Affinity DataKi:  1.30E+3nMAssay Description:Binding affinity of the compound towards human Endothelin B receptor by measuring its ability to displace [125I]-ET-3 from guinea pig cerebellumMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin receptor type B(Homo sapiens (Human))
Basf

Curated by ChEMBL
LigandPNGBDBM50050805(2-(4,6-Dimethoxy-pyrimidin-2-yloxy)-3-methoxy-3,3-...)
Affinity DataKi:  1.30E+3nMAssay Description:Binding affinity of the compound towards human Endothelin B receptor by measuring its ability to displace [125I]-ET-3 from guinea pig cerebellumMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin receptor type B(Homo sapiens (Human))
Basf

Curated by ChEMBL
LigandPNGBDBM50050788(2-(4,6-Dimethoxy-pyrimidin-2-yloxy)-3-methoxy-3,3-...)
Affinity DataKi:  1.30E+3nMAssay Description:Binding affinity of the compound towards human Endothelin B receptor by measuring its ability to displace [125I]-ET-3 from guinea pig cerebellumMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin receptor type B(Homo sapiens (Human))
Basf

Curated by ChEMBL
LigandPNGBDBM50050804(2-(4,6-Dimethoxy-pyrimidin-2-yloxy)-3-(3,3-dimethy...)
Affinity DataKi:  1.40E+3nMAssay Description:Binding affinity of the compound towards human Endothelin B receptor by measuring its ability to displace [125I]-ET-3 from guinea pig cerebellumMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin receptor type B(Homo sapiens (Human))
Basf

Curated by ChEMBL
LigandPNGBDBM50050792(2-(4,6-Dimethoxy-pyrimidin-2-yloxy)-3-phenoxy-3,3-...)
Affinity DataKi:  1.50E+3nMAssay Description:Binding affinity of the compound towards human Endothelin B receptor by measuring its ability to displace [125I]-ET-3 from guinea pig cerebellumMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin receptor type B(Homo sapiens (Human))
Basf

Curated by ChEMBL
LigandPNGBDBM50050795(2-(4,6-Dimethoxy-pyrimidin-2-yloxy)-3,3-diphenyl-3...)
Affinity DataKi:  1.70E+3nMAssay Description:Binding affinity of the compound towards human Endothelin B receptor by measuring its ability to displace [125I]-ET-3 from guinea pig cerebellumMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin receptor type B(Homo sapiens (Human))
Basf

Curated by ChEMBL
LigandPNGBDBM50050790(2-(4,6-Dimethoxy-pyrimidin-2-yloxy)-3,3-bis-(3-flu...)
Affinity DataKi:  1.80E+3nMAssay Description:Binding affinity of the compound towards human Endothelin B receptor by measuring its ability to displace [125I]-ET-3 from guinea pig cerebellumMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin receptor type B(Homo sapiens (Human))
Basf

Curated by ChEMBL
LigandPNGBDBM50050810(3-Methoxy-2-(4-methyl-pyrimidin-2-yloxy)-3,3-diphe...)
Affinity DataKi:  1.90E+3nMAssay Description:Binding affinity of the compound towards human Endothelin B receptor by measuring its ability to displace [125I]-ET-3 from guinea pig cerebellumMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin receptor type B(Homo sapiens (Human))
Basf

Curated by ChEMBL
LigandPNGBDBM50050802(2-(4,6-Dimethoxy-pyrimidin-2-yloxy)-3-ethoxy-3,3-d...)
Affinity DataKi:  2.50E+3nMAssay Description:Binding affinity of the compound towards human Endothelin B receptor by measuring its ability to displace [125I]-ET-3 from guinea pig cerebellumMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin receptor type B(Homo sapiens (Human))
Basf

Curated by ChEMBL
LigandPNGBDBM50050801(2-(4,6-Diethoxy-pyrimidin-2-yloxy)-3-methoxy-3,3-d...)
Affinity DataKi:  2.50E+3nMAssay Description:Binding affinity of the compound towards human Endothelin B receptor by measuring its ability to displace [125I]-ET-3 from guinea pig cerebellumMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin receptor type B(Homo sapiens (Human))
Basf

Curated by ChEMBL
LigandPNGBDBM50050809(2-(4,6-Dimethoxy-pyrimidin-2-yloxy)-3-(4-isopropyl...)
Affinity DataKi:  3.00E+3nMAssay Description:Binding affinity of the compound towards human Endothelin B receptor by measuring its ability to displace [125I]-ET-3 from CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin receptor type B(Homo sapiens (Human))
Basf

Curated by ChEMBL
LigandPNGBDBM50050803(2-(4,6-Dimethoxy-pyrimidin-2-yloxy)-3-hydroxy-3,3-...)
Affinity DataKi:  3.50E+3nMAssay Description:Binding affinity of the compound towards human Endothelin B receptor by measuring its ability to displace [125I]-ET-3 from guinea pig cerebellumMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin receptor type B(Homo sapiens (Human))
Basf

Curated by ChEMBL
LigandPNGBDBM50050798(2-(4,6-Dimethoxy-pyrimidin-2-yloxy)-3-(4-methylsul...)
Affinity DataKi:  4.70E+3nMAssay Description:Binding affinity of the compound towards human Endothelin B receptor by measuring its ability to displace [125I]-ET-3 from CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin receptor type B(Homo sapiens (Human))
Basf

Curated by ChEMBL
LigandPNGBDBM50050808(2-(4,6-Dimethoxy-pyrimidin-2-yloxy)-3,3-bis-(2-flu...)
Affinity DataKi:  6.00E+3nMAssay Description:Binding affinity of the compound towards human Endothelin B receptor by measuring its ability to displace [125I]-ET-3 from guinea pig cerebellumMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed