Compile Data Set for Download or QSAR
Report error Found 14 Enz. Inhib. hit(s) with all data for entry = 50006625
TargetDimer of Protein farnesyltransferase subunit beta(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50051826([4-((R)-2-Amino-3-mercapto-propyl)-3-butyl-piperaz...)
Affinity DataIC50: 1nMAssay Description:Inhibition of [3H]FPP incorporation into Ha-Ras by FarnesyltransferaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDimer of Protein farnesyltransferase subunit beta(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50051825([(S)-4-((R)-2-Amino-3-mercapto-propyl)-3-(2-cyclop...)
Affinity DataIC50: 1nMAssay Description:Inhibition of [3H]FPP incorporation into Ha-Ras by FarnesyltransferaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDimer of Protein farnesyltransferase subunit beta(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50051823([(S)-4-((R)-2-Amino-3-mercapto-propyl)-3-(2-methox...)
Affinity DataIC50: 3nMAssay Description:Inhibition of [3H]FPP incorporation into Ha-Ras by FarnesyltransferaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDimer of Protein farnesyltransferase subunit beta(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50051824([(S)-4-((R)-2-Amino-3-mercapto-propyl)-3-butyl-pip...)
Affinity DataIC50: 5nMAssay Description:Inhibition of [3H]FPP incorporation into Ha-Ras by FarnesyltransferaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDimer of Protein farnesyltransferase subunit beta(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50051821([(S)-4-((R)-2-Amino-3-mercapto-propyl)-3-butyl-pip...)
Affinity DataIC50: 24nMAssay Description:Inhibition of [3H]FPP incorporation into Ha-Ras by FarnesyltransferaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDimer of Protein farnesyltransferase subunit beta(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50051822([(S)-4-((R)-2-Amino-3-mercapto-propyl)-3-ethyl-pip...)
Affinity DataIC50: 68nMAssay Description:Inhibition of [3H]FPP incorporation into Ha-Ras by FarnesyltransferaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDimer of Protein farnesyltransferase subunit beta(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50051827([4-((R)-2-Amino-3-mercapto-propyl)-piperazin-1-yl]...)
Affinity DataIC50: 160nMAssay Description:Inhibition of [3H]FPP incorporation into Ha-Ras by FarnesyltransferaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50051826([4-((R)-2-Amino-3-mercapto-propyl)-3-butyl-piperaz...)
Affinity DataIC50: 160nMAssay Description:Inhibition of bovine Geranylgeranyl transferase type IMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50051824([(S)-4-((R)-2-Amino-3-mercapto-propyl)-3-butyl-pip...)
Affinity DataIC50: 360nMAssay Description:Inhibition of bovine Geranylgeranyl transferase type IMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50051823([(S)-4-((R)-2-Amino-3-mercapto-propyl)-3-(2-methox...)
Affinity DataIC50: 500nMAssay Description:Inhibition of post-traslational processing of Ras protein in RAT1 cell lineMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50051825([(S)-4-((R)-2-Amino-3-mercapto-propyl)-3-(2-cyclop...)
Affinity DataIC50: 500nMAssay Description:Inhibition of post-traslational processing of Ras protein in RAT1 cell lineMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50051826([4-((R)-2-Amino-3-mercapto-propyl)-3-butyl-piperaz...)
Affinity DataIC50: 500nMAssay Description:Inhibition of post-traslational processing of Ras protein in RAT1 cell lineMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50051827([4-((R)-2-Amino-3-mercapto-propyl)-piperazin-1-yl]...)
Affinity DataIC50: 2.80E+3nMAssay Description:Inhibition of bovine Geranylgeranyl transferase type IMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50051823([(S)-4-((R)-2-Amino-3-mercapto-propyl)-3-(2-methox...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of bovine Geranylgeranyl transferase type IMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed