Compile Data Set for Download or QSAR
Report error Found 55 Enz. Inhib. hit(s) with all data for entry = 50006742
TargetATP-citrate synthase(Rat)
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50053000BDBM50053000(2-[8-(2,4-Dichloro-phenyl)-2-oxo-octyl]-2-hydroxy-...)
Affinity DataKi:  1.20E+3nMAssay Description:Inhibitory activity against rat ATP-citrate lyase activity by the maleate dehydrogenase catalyzed reduction of oxaloacetate by NADH.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetATP-citrate synthase(Rat)
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50053001BDBM50053001(2-[6-(2,4-Dichloro-phenyl)-hexylsulfanylmethyl]-su...)
Affinity DataKi:  2.60E+3nMAssay Description:Inhibitory activity against rat ATP-citrate lyase activity by the maleate dehydrogenase catalyzed reduction of oxaloacetate by NADH.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetATP-citrate synthase(Rat)
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50052995BDBM50052995(2-{2-[5-(2,4-Dichloro-phenyl)-pentylsulfanyl]-ethy...)
Affinity DataKi:  2.90E+3nMAssay Description:Inhibitory activity against rat ATP-citrate lyase activity by the maleate dehydrogenase catalyzed reduction of oxaloacetate by NADH.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetATP-citrate synthase(Rat)
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50052989BDBM50052989(2-[8-(2,4-Dichloro-phenyl)-octyl]-2-hydroxy-succin...)
Affinity DataKi:  2.90E+3nMAssay Description:Inhibitory activity against rat ATP-citrate lyase activity by the maleate dehydrogenase catalyzed reduction of oxaloacetate by NADH.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetATP-citrate synthase(Rat)
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50053020BDBM50053020(2-[6-(2,4-Dichloro-phenyl)-hexylsulfanylmethyl]-2-...)
Affinity DataKi:  3.30E+3nMAssay Description:Inhibition of recombinant ATP-Citrate Lyase activity as maleate dehydrogenase catalyzed reduction of oxaloacetate by NADHMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetATP-citrate synthase(Rat)
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50052985BDBM50052985(2-[5-(2,4-Dichloro-phenyl)-pentylsulfanylmethyl]-2...)
Affinity DataKi:  6.80E+3nMAssay Description:Inhibition of recombinant ATP-Citrate Lyase activity as maleate dehydrogenase catalyzed reduction of oxaloacetate by NADHMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetATP-citrate synthase(Rat)
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50053010BDBM50053010(2-[7-(2,4-Dichloro-phenyl)-heptylsulfanylmethyl]-2...)
Affinity DataKi:  7.20E+3nMAssay Description:Inhibitory activity against rat ATP-citrate lyase activity by the maleate dehydrogenase catalyzed reduction of oxaloacetate by NADH.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetATP-citrate synthase(Rat)
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50052980BDBM50052980(2-[6-(2,3-Dichloro-phenyl)-hexylsulfanylmethyl]-2-...)
Affinity DataKi:  7.30E+3nMAssay Description:Inhibitory activity against rat ATP-citrate lyase activity by the maleate dehydrogenase catalyzed reduction of oxaloacetate by NADH.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetATP-citrate synthase(Rat)
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50053016BDBM50053016(2-[(E)-6-(2,4-Dichloro-phenyl)-hex-5-enylsulfanylm...)
Affinity DataKi:  7.40E+3nMAssay Description:Inhibitory activity against rat ATP-citrate lyase activity by the maleate dehydrogenase catalyzed reduction of oxaloacetate by NADH.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetATP-citrate synthase(Rat)
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50053029BDBM50053029(2-[6-(3,5-Dichloro-biphenyl-2-yl)-hexylsulfanylmet...)
Affinity DataKi:  1.00E+4nMAssay Description:Inhibition of recombinant ATP-Citrate Lyase activity as maleate dehydrogenase catalyzed reduction of oxaloacetate by NADHMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetATP-citrate synthase(Rat)
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50053018BDBM50053018(2-[5-(2,4-Dichloro-phenylsulfanyl)-pentylsulfanylm...)
Affinity DataKi:  1.00E+4nMAssay Description:Inhibitory activity against rat ATP-citrate lyase activity by the maleate dehydrogenase catalyzed reduction of oxaloacetate by NADH.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetATP-citrate synthase(Rat)
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50053027BDBM50053027(2-[7-(2,4-Dichloro-phenyl)-heptyl]-2-hydroxy-succi...)
Affinity DataKi:  1.05E+4nMAssay Description:Inhibitory activity against rat ATP-citrate lyase activity by the maleate dehydrogenase catalyzed reduction of oxaloacetate by NADH.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetATP-citrate synthase(Rat)
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50052991BDBM50052991(2-[5-(2,4-Dichloro-phenylamino)-pentylsulfanylmeth...)
Affinity DataKi:  1.20E+4nMAssay Description:Inhibitory activity against rat ATP-citrate lyase activity by the maleate dehydrogenase catalyzed reduction of oxaloacetate by NADH.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetATP-citrate synthase(Rat)
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50053015BDBM50053015(2-(6-Biphenyl-2-yl-hexylsulfanylmethyl)-2-hydroxy-...)
Affinity DataKi:  1.80E+4nMAssay Description:Inhibitory activity against rat ATP-citrate lyase activity by the maleate dehydrogenase catalyzed reduction of oxaloacetate by NADH.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetATP-citrate synthase(Rat)
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50053005BDBM50053005(2-(5-Biphenyl-2-yl-pentylsulfanylmethyl)-2-hydroxy...)
Affinity DataKi:  2.10E+4nMAssay Description:Inhibitory activity against rat ATP-citrate lyase activity by the maleate dehydrogenase catalyzed reduction of oxaloacetate by NADH.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetATP-citrate synthase(Rat)
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50053011BDBM50053011(4-[6-(2,4-Dichloro-phenyl)-hexylsulfanyl]-butyric ...)
Affinity DataKi:  2.50E+4nMAssay Description:Inhibitory activity against rat ATP-citrate lyase activity by the maleate dehydrogenase catalyzed reduction of oxaloacetate by NADH.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetATP-citrate synthase(Rat)
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50053007BDBM50053007(2-[7-(2,4-Dichloro-phenyl)-2-oxo-heptyl]-2-hydroxy...)
Affinity DataKi:  2.50E+4nMAssay Description:Inhibitory activity against rat ATP-citrate lyase activity by the maleate dehydrogenase catalyzed reduction of oxaloacetate by NADH.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetATP-citrate synthase(Human)
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50052987BDBM50052987(2-[6-(4-Chloro-2-nitro-phenyl)-hexylsulfanylmethyl...)
Affinity DataKi:  2.60E+4nMAssay Description:Inhibitory activity against rat ATP-Citrate Lyase activity was measured by the maleate dehydrogenase catalyzed reduction of oxaloacetate by NADHMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetATP-citrate synthase(Rat)
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50053008BDBM50053008(2-[6-(4-Bromo-phenyl)-hexylsulfanylmethyl]-2-hydro...)
Affinity DataKi:  3.10E+4nMAssay Description:Inhibitory activity against rat ATP-citrate lyase activity by the maleate dehydrogenase catalyzed reduction of oxaloacetate by NADH.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetATP-citrate synthase(Rat)
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50052996BDBM50052996(2-[(Z)-6-(2,4-Dichloro-phenyl)-hex-5-enylsulfanylm...)
Affinity DataKi:  3.30E+4nMAssay Description:Inhibitory activity against rat ATP-citrate lyase activity by the maleate dehydrogenase catalyzed reduction of oxaloacetate by NADH.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetATP-citrate synthase(Rat)
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50053014BDBM50053014(2-(6-Biphenyl-4-yl-hexylsulfanylmethyl)-2-hydroxy-...)
Affinity DataKi:  3.80E+4nMAssay Description:Inhibitory activity against rat ATP-citrate lyase activity by the maleate dehydrogenase catalyzed reduction of oxaloacetate by NADH.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetATP-citrate synthase(Rat)
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50052993BDBM50052993(2-Hydroxy-2-(6-naphthalen-1-yl-hexylsulfanylmethyl...)
Affinity DataKi:  6.30E+4nMAssay Description:Inhibition of recombinant ATP-Citrate Lyase activity as maleate dehydrogenase catalyzed reduction of oxaloacetate by NADHMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetATP-citrate synthase(Rat)
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50053006BDBM50053006(2-[5-(2,4-Dichloro-benzenesulfonyl)-pentylsulfanyl...)
Affinity DataKi:  6.40E+4nMAssay Description:Inhibitory activity against rat ATP-citrate lyase activity by the maleate dehydrogenase catalyzed reduction of oxaloacetate by NADH.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetATP-citrate synthase(Rat)
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50053012BDBM50053012(2-[5-(2,4-Dichloro-phenoxy)-pentylsulfanylmethyl]-...)
Affinity DataKi:  6.70E+4nMAssay Description:Inhibitory activity against rat ATP-citrate lyase activity by the maleate dehydrogenase catalyzed reduction of oxaloacetate by NADH.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetATP-citrate synthase(Rat)
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50053003BDBM50053003(2-[6-(2-Chloro-phenyl)-hexylsulfanylmethyl]-2-hydr...)
Affinity DataKi:  6.90E+4nMAssay Description:Inhibitory activity against rat ATP-citrate lyase activity by the maleate dehydrogenase catalyzed reduction of oxaloacetate by NADH.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetATP-citrate synthase(Rat)
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50053028BDBM50053028(2-[6-(4-Chloro-phenyl)-hexylsulfanylmethyl]-2-hydr...)
Affinity DataKi:  7.10E+4nMAssay Description:Inhibitory activity against rat ATP-citrate lyase activity by the maleate dehydrogenase catalyzed reduction of oxaloacetate by NADH.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetATP-citrate synthase(Rat)
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50052983BDBM50052983(2-Hydroxy-2-[6-(2-nitro-phenyl)-hexylsulfanylmethy...)
Affinity DataKi:  7.50E+4nMAssay Description:Inhibition of recombinant ATP-Citrate Lyase activity as maleate dehydrogenase catalyzed reduction of oxaloacetate by NADHMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetATP-citrate synthase(Rat)
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50053002BDBM50053002(2-[6-(2,6-Dichloro-phenyl)-hexylsulfanylmethyl]-2-...)
Affinity DataKi:  7.60E+4nMAssay Description:Inhibitory activity against rat ATP-citrate lyase activity by the maleate dehydrogenase catalyzed reduction of oxaloacetate by NADH.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetATP-citrate synthase(Rat)
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50053024BDBM50053024(4-[6-(2,4-Dichloro-phenyl)-hexylsulfanyl]-3-hydrox...)
Affinity DataKi:  8.80E+4nMAssay Description:Inhibitory activity against rat ATP-citrate lyase activity by the maleate dehydrogenase catalyzed reduction of oxaloacetate by NADH.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetATP-citrate synthase(Rat)
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50052999BDBM50052999(2-Hydroxy-2-(6-naphthalen-2-yl-hexylsulfanylmethyl...)
Affinity DataKi:  9.30E+4nMAssay Description:Inhibition of recombinant ATP-Citrate Lyase activity as maleate dehydrogenase catalyzed reduction of oxaloacetate by NADHMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetATP-citrate synthase(Rat)
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50053022BDBM50053022(2-[6-(2-Benzyl-phenyl)-hexylsulfanylmethyl]-2-hydr...)
Affinity DataKi:  9.40E+4nMAssay Description:Inhibition of recombinant ATP-Citrate Lyase activity as maleate dehydrogenase catalyzed reduction of oxaloacetate by NADHMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetATP-citrate synthase(Rat)
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50052988BDBM50052988(2-[6-(3,4-Dichloro-phenyl)-hexylsulfanylmethyl]-2-...)
Affinity DataKi:  1.10E+5nMAssay Description:Inhibitory activity against rat ATP-citrate lyase activity by the maleate dehydrogenase catalyzed reduction of oxaloacetate by NADH.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetATP-citrate synthase(Rat)
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50052994BDBM50052994(2-[6-(4-Fluoro-phenyl)-hexylsulfanylmethyl]-2-hydr...)
Affinity DataKi:  1.20E+5nMAssay Description:Inhibitory activity against rat ATP-citrate lyase activity by the maleate dehydrogenase catalyzed reduction of oxaloacetate by NADH.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetATP-citrate synthase(Human)
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50053013BDBM50053013(2-[6-(3,5-Dichloro-pyridin-4-yl)-hexylsulfanylmeth...)
Affinity DataKi:  1.21E+5nMAssay Description:Inhibitory activity against human recombinant ATP-Citrate Lyase activity was measured by the maleate dehydrogenase catalyzed reduction of oxaloacetat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetATP-citrate synthase(Rat)
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50053030BDBM50053030(2-[6-(2,4-Dichloro-phenyl)-6-oxo-hexylsulfanylmeth...)
Affinity DataKi:  1.30E+5nMAssay Description:Inhibitory activity against rat ATP-citrate lyase activity by the maleate dehydrogenase catalyzed reduction of oxaloacetate by NADH.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetATP-citrate synthase(Rat)
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50052997BDBM50052997(2-[5-(2,4-Dichloro-benzenesulfinyl)-pentylsulfanyl...)
Affinity DataKi:  1.31E+5nMAssay Description:Inhibitory activity against rat ATP-citrate lyase activity by the maleate dehydrogenase catalyzed reduction of oxaloacetate by NADH.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetATP-citrate synthase(Rat)
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50052978BDBM50052978(2-[6-(3-Chloro-phenyl)-hexylsulfanylmethyl]-2-hydr...)
Affinity DataKi:  1.50E+5nMAssay Description:Inhibitory activity against rat ATP-citrate lyase activity by the maleate dehydrogenase catalyzed reduction of oxaloacetate by NADH.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetATP-citrate synthase(Rat)
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50053017BDBM50053017(2-[6-(2,4-Dimethyl-phenyl)-hexylsulfanylmethyl]-2-...)
Affinity DataKi:  1.60E+5nMAssay Description:Inhibition of recombinant ATP-Citrate Lyase activity as maleate dehydrogenase catalyzed reduction of oxaloacetate by NADHMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetATP-citrate synthase(Rat)
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50053026BDBM50053026(2-[4-(2,4-Dichloro-benzenesulfonylamino)-butylsulf...)
Affinity DataKi:  1.75E+5nMAssay Description:Inhibitory activity against rat ATP-citrate lyase activity by the maleate dehydrogenase catalyzed reduction of oxaloacetate by NADH.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetATP-citrate synthase(Rat)
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50053023BDBM50053023(2-{4-[(2,4-Dichloro-benzenesulfonyl)-methyl-amino]...)
Affinity DataKi:  1.78E+5nMAssay Description:Inhibitory activity against rat ATP-citrate lyase activity by the maleate dehydrogenase catalyzed reduction of oxaloacetate by NADH.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetATP-citrate synthase(Rat)
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50052979BDBM50052979(2-(5-Biphenyl-4-yl-pentylsulfanylmethyl)-2-hydroxy...)
Affinity DataKi:  2.26E+5nMAssay Description:Inhibitory activity against rat ATP-citrate lyase activity by the maleate dehydrogenase catalyzed reduction of oxaloacetate by NADH.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetATP-citrate synthase(Rat)
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50052981BDBM50052981(2-[6-(2,4-Difluoro-phenyl)-hexylsulfanylmethyl]-2-...)
Affinity DataKi:  2.70E+5nMAssay Description:Inhibition of recombinant ATP-Citrate Lyase activity as maleate dehydrogenase catalyzed reduction of oxaloacetate by NADHMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetATP-citrate synthase(Rat)
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50052982BDBM50052982(2-Hydroxy-2-[6-(4-methoxy-phenyl)-hexylsulfanylmet...)
Affinity DataKi:  2.80E+5nMAssay Description:Inhibition of recombinant ATP-Citrate Lyase activity as maleate dehydrogenase catalyzed reduction of oxaloacetate by NADHMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetATP-citrate synthase(Rat)
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50053009BDBM50053009(2-[9-(2,4-Dichloro-phenyl)-nonylsulfanylmethyl]-2-...)
Affinity DataKi:  3.00E+5nMAssay Description:Inhibitory activity against rat ATP-citrate lyase activity by the maleate dehydrogenase catalyzed reduction of oxaloacetate by NADH.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetATP-citrate synthase(Human)
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50052984BDBM50052984(2-Hydroxy-2-(3-naphthalen-2-yl-propylsulfanylmethy...)
Affinity DataKi:  3.00E+5nMAssay Description:Inhibitory activity against human recombinant ATP-Citrate Lyase activity was measured by the maleate dehydrogenase catalyzed reduction of oxaloacetat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetATP-citrate synthase(Human)
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50052992BDBM50052992(2-Hydroxy-2-(6-phenyl-hexylsulfanylmethyl)-succini...)
Affinity DataKi:  3.20E+5nMAssay Description:Inhibitory activity against human recombinant ATP-Citrate Lyase was measured by the maleate dehydrogenase catalyzed reduction of oxaloacetate by NADHMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetATP-citrate synthase(Rat)
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50053021BDBM50053021(2-Hydroxy-2-[6-(4-nitro-phenyl)-hexylsulfanylmethy...)
Affinity DataKi:  3.40E+5nMAssay Description:Inhibitory activity against human recombinant ATP-Citrate Lyase activity was measured by the maleate dehydrogenase catalyzed reduction of oxaloacetat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetATP-citrate synthase(Rat)
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50053025BDBM50053025(2-[3-(2,4-Dichloro-phenyl)-propylsulfanylmethyl]-2...)
Affinity DataKi:  3.90E+5nMAssay Description:Inhibition of recombinant ATP-Citrate Lyase activity as maleate dehydrogenase catalyzed reduction of oxaloacetate by NADHMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetATP-citrate synthase(Rat)
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50053004BDBM50053004(2-(2,4-Dichloro-benzylsulfanylmethyl)-2-hydroxy-su...)
Affinity DataKi:  4.10E+5nMAssay Description:Inhibitory activity against rat ATP-citrate lyase activity by the maleate dehydrogenase catalyzed reduction of oxaloacetate by NADH.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetATP-citrate synthase(Rat)
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50052998BDBM50052998(2-Hydroxy-2-[6-(4-hydroxy-phenyl)-hexylsulfanylmet...)
Affinity DataKi:  4.20E+5nMAssay Description:Inhibitory activity against rat ATP-citrate lyase activity by the maleate dehydrogenase catalyzed reduction of oxaloacetate by NADH.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
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