Compile Data Set for Download or QSAR
Report error Found 37 Enz. Inhib. hit(s) with all data for entry = 50006995
TargetGlutamate receptor ionotropic, NMDA 1(Rat)
Cocensys

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50056605BDBM50056605(7-Chloro-6-methyl-5-nitro-1,4-dihydro-quinoxaline-...)
Affinity DataIC50: 4.70nMAssay Description:Potency for the N-methyl-D-aspartate glutamate receptor 1 glycine site by displacement of [3H]5,7-dichlorokynurenic acid (DCKA) binding in rat brain ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGlutamate receptor ionotropic, NMDA 1(Rat)
Cocensys

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50038161BDBM50038161(6,7-Dichloro-5-nitro-1,4-dihydro-quinoxaline-2,3-d...)
Affinity DataIC50: 5.90nMAssay Description:Potency for the N-methyl-D-aspartate glutamate receptor 1 glycine site by displacement of [3H]5,7-dichlorokynurenic acid (DCKA) binding in rat brain ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGlutamate receptor ionotropic, NMDA 1(Rat)
Cocensys

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50056596BDBM50056596(7-Bromo-6-methyl-5-nitro-1,4-dihydro-quinoxaline-2...)
Affinity DataIC50: 8.70nMAssay Description:Potency for the N-methyl-D-aspartate glutamate receptor 1 glycine site by displacement of [3H]5,7-dichlorokynurenic acid (DCKA) binding in rat brain ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGlutamate receptor ionotropic, NMDA 1(Rat)
Cocensys

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50056618BDBM50056618(6,7-Dibromo-5-nitro-1,4-dihydro-quinoxaline-2,3-di...)
Affinity DataIC50: 20nMAssay Description:Potency for the N-methyl-D-aspartate glutamate receptor 1 glycine site by displacement of [3H]5,7-dichlorokynurenic acid (DCKA) binding in rat brain ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGlutamate receptor ionotropic, NMDA 1(Rat)
Cocensys

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50056595BDBM50056595(6,7-Dimethyl-5-nitro-1,4-dihydro-quinoxaline-2,3-d...)
Affinity DataIC50: 29nMAssay Description:Potency for the N-methyl-D-aspartate glutamate receptor 1 glycine site by displacement of [3H]5,7-dichlorokynurenic acid (DCKA) binding in rat brain ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGlutamate receptor ionotropic, NMDA 1(Rat)
Cocensys

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50056620BDBM50056620(6-Chloro-7-ethyl-5-nitro-1,4-dihydro-quinoxaline-2...)
Affinity DataIC50: 29nMAssay Description:Potency for the N-methyl-D-aspartate glutamate receptor 1 glycine site by displacement of [3H]5,7-dichlorokynurenic acid (DCKA) binding in rat brain ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGlutamate receptor ionotropic, NMDA 1(Rat)
Cocensys

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50056600BDBM50056600(6-Chloro-7-methyl-5-nitro-1,4-dihydro-quinoxaline-...)
Affinity DataIC50: 45nMAssay Description:Potency for the N-methyl-D-aspartate glutamate receptor 1 glycine site by displacement of [3H]5,7-dichlorokynurenic acid (DCKA) binding in rat brain ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGlutamate receptor ionotropic, NMDA 1(Rat)
Cocensys

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50056591BDBM50056591(7-Bromo-6-methoxy-5-nitro-1,4-dihydro-quinoxaline-...)
Affinity DataIC50: 64nMAssay Description:Potency for the N-methyl-D-aspartate glutamate receptor 1 glycine site by displacement of [3H]5,7-dichlorokynurenic acid (DCKA) binding in rat brain ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGlutamate receptor ionotropic, NMDA 1(Rat)
Cocensys

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50056598BDBM50056598(7-Methyl-8-nitro-2,3-dioxo-1,2,3,4-tetrahydro-quin...)
Affinity DataIC50: 73nMAssay Description:Potency for the N-methyl-D-aspartate glutamate receptor 1 glycine site by displacement of [3H]5,7-dichlorokynurenic acid (DCKA) binding in rat brain ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGlutamate receptor ionotropic, NMDA 1(Rat)
Cocensys

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50056611BDBM50056611(6-Bromo-7-ethyl-5-nitro-1,4-dihydro-quinoxaline-2,...)
Affinity DataIC50: 82nMAssay Description:Potency for the N-methyl-D-aspartate glutamate receptor 1 glycine site by displacement of [3H]5,7-dichlorokynurenic acid (DCKA) binding in rat brain ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGlutamate receptor ionotropic, NMDA 1(Rat)
Cocensys

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50056597BDBM50056597(7-Fluoro-6-methyl-5-nitro-1,4-dihydro-quinoxaline-...)
Affinity DataIC50: 95nMAssay Description:Potency for the N-methyl-D-aspartate glutamate receptor 1 glycine site by displacement of [3H]5,7-dichlorokynurenic acid (DCKA) binding in rat brain ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGlutamate receptor ionotropic, NMDA 1(Rat)
Cocensys

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 22778BDBM22778(6,7-Dichloro-1,4-dihydro-quinoxaline-2,3-dione | C...)
Affinity DataIC50: 130nMAssay Description:Potency for the N-methyl-D-aspartate glutamate receptor 1 glycine site by displacement of [3H]5,7-dichlorokynurenic acid (DCKA) binding in rat brain ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGlutamate receptor ionotropic, NMDA 1(Rat)
Cocensys

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50056592BDBM50056592(7-Chloro-6-ethyl-5-nitro-1,4-dihydro-quinoxaline-2...)
Affinity DataIC50: 130nMAssay Description:Potency for the N-methyl-D-aspartate glutamate receptor 1 glycine site by displacement of [3H]5,7-dichlorokynurenic acid (DCKA) binding in rat brain ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGlutamate receptor ionotropic, NMDA 1(Rat)
Cocensys

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50056615BDBM50056615(5-Amino-7-chloro-6-methyl-1,4-dihydro-quinoxaline-...)
Affinity DataIC50: 150nMAssay Description:Potency for the N-methyl-D-aspartate glutamate receptor 1 glycine site by displacement of [3H]5,7-dichlorokynurenic acid (DCKA) binding in rat brain ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGlutamate receptor ionotropic, NMDA 1(Rat)
Cocensys

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50056621BDBM50056621(7-Chloro-6-methoxy-5-nitro-1,4-dihydro-quinoxaline...)
Affinity DataIC50: 150nMAssay Description:Potency for the N-methyl-D-aspartate glutamate receptor 1 glycine site by displacement of [3H]5,7-dichlorokynurenic acid (DCKA) binding in rat brain ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGlutamate receptor ionotropic, NMDA 1(Rat)
Cocensys

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50056606BDBM50056606(6,7-Diethyl-5-nitro-1,4-dihydro-quinoxaline-2,3-di...)
Affinity DataIC50: 160nMAssay Description:Potency for the N-methyl-D-aspartate glutamate receptor 1 glycine site by displacement of [3H]5,7-dichlorokynurenic acid (DCKA) binding in rat brain ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGlutamate receptor ionotropic, NMDA 1(Rat)
Cocensys

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50056593BDBM50056593(7-Chloro-6-ethylsulfanyl-5-nitro-1,4-dihydro-quino...)
Affinity DataIC50: 640nMAssay Description:Potency for the N-methyl-D-aspartate glutamate receptor 1 glycine site by displacement of [3H]5,7-dichlorokynurenic acid (DCKA) binding in rat brain ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGlutamate receptor ionotropic, NMDA 1(Rat)
Cocensys

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50056622BDBM50056622(6-Chloro-7-methyl-1,4-dihydro-quinoxaline-2,3-dion...)
Affinity DataIC50: 780nMAssay Description:Potency for the N-methyl-D-aspartate glutamate receptor 1 glycine site by displacement of [3H]5,7-dichlorokynurenic acid (DCKA) binding in rat brain ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGlutamate receptor ionotropic, NMDA 1(Rat)
Cocensys

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50056614BDBM50056614(6-Bromo-7-methoxy-1,4-dihydro-quinoxaline-2,3-dion...)
Affinity DataIC50: 1.00E+3nMAssay Description:Potency for the N-methyl-D-aspartate glutamate receptor 1 glycine site by displacement of [3H]5,7-dichlorokynurenic acid (DCKA) binding in rat brain ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGlutamate receptor ionotropic, NMDA 1(Rat)
Cocensys

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50056613BDBM50056613(6-Chloro-7-ethyl-1,4-dihydro-quinoxaline-2,3-dione...)
Affinity DataIC50: 1.40E+3nMAssay Description:Potency for the N-methyl-D-aspartate glutamate receptor 1 glycine site by displacement of [3H]5,7-dichlorokynurenic acid (DCKA) binding in rat brain ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGlutamate receptor ionotropic, NMDA 1(Rat)
Cocensys

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50056623BDBM50056623(6,7-Diethyl-1,4-dihydro-quinoxaline-2,3-dione | CH...)
Affinity DataIC50: 1.80E+3nMAssay Description:Potency for the N-methyl-D-aspartate glutamate receptor 1 glycine site by displacement of [3H]5,7-dichlorokynurenic acid (DCKA) binding in rat brain ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGlutamate receptor ionotropic, NMDA 1(Rat)
Cocensys

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50056610BDBM50056610(7-Fluoro-6-methoxy-5-nitro-1,4-dihydro-quinoxaline...)
Affinity DataIC50: 1.90E+3nMAssay Description:Potency for the N-methyl-D-aspartate glutamate receptor 1 glycine site by displacement of [3H]5,7-dichlorokynurenic acid (DCKA) binding in rat brain ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGlutamate receptor ionotropic, NMDA 1(Rat)
Cocensys

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50056594BDBM50056594(8-Nitro-2,3-dioxo-1,2,3,4-tetrahydro-quinoxaline-6...)
Affinity DataIC50: 2.80E+3nMAssay Description:Potency for the N-methyl-D-aspartate glutamate receptor 1 glycine site by displacement of [3H]5,7-dichlorokynurenic acid (DCKA) binding in rat brain ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGlutamate receptor ionotropic, NMDA 1(Rat)
Cocensys

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50056602BDBM50056602(5-Nitro-4,6,7,8-tetrahydro-1H-cyclopenta[g]quinoxa...)
Affinity DataIC50: 3.10E+3nMAssay Description:Potency for the N-methyl-D-aspartate glutamate receptor 1 glycine site by displacement of [3H]5,7-dichlorokynurenic acid (DCKA) binding in rat brain ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGlutamate receptor ionotropic, NMDA 1(Rat)
Cocensys

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50008768BDBM50008768(CHEMBL22720 | 6,7-Dimethyl-1,4-dihydro-quinoxaline...)
Affinity DataIC50: 3.30E+3nMAssay Description:Potency for the N-methyl-D-aspartate glutamate receptor 1 glycine site by displacement of [3H]5,7-dichlorokynurenic acid (DCKA) binding in rat brain ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGlutamate receptor ionotropic, NMDA 1(Rat)
Cocensys

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50056616BDBM50056616(6-Ethoxy-7-fluoro-5-nitro-1,4-dihydro-quinoxaline-...)
Affinity DataIC50: 3.60E+3nMAssay Description:Potency for the N-methyl-D-aspartate glutamate receptor 1 glycine site by displacement of [3H]5,7-dichlorokynurenic acid (DCKA) binding in rat brain ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGlutamate receptor ionotropic, NMDA 1(Rat)
Cocensys

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50056617BDBM50056617(7-Fluoro-5-nitro-6-(3-phenyl-propoxy)-1,4-dihydro-...)
Affinity DataIC50: 4.00E+3nMAssay Description:Potency for the N-methyl-D-aspartate glutamate receptor 1 glycine site by displacement of [3H]5,7-dichlorokynurenic acid (DCKA) binding in rat brain ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGlutamate receptor ionotropic, NMDA 1(Rat)
Cocensys

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50056624BDBM50056624(6-Butoxy-7-fluoro-5-nitro-1,4-dihydro-quinoxaline-...)
Affinity DataIC50: 4.30E+3nMAssay Description:Potency for the N-methyl-D-aspartate glutamate receptor 1 glycine site by displacement of [3H]5,7-dichlorokynurenic acid (DCKA) binding in rat brain ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGlutamate receptor ionotropic, NMDA 1(Rat)
Cocensys

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50056601BDBM50056601(7-Methyl-5-nitro-1,4-dihydro-quinoxaline-2,3-dione...)
Affinity DataIC50: 9.30E+3nMAssay Description:Potency for the N-methyl-D-aspartate glutamate receptor 1 glycine site by displacement of [3H]5,7-dichlorokynurenic acid (DCKA) binding in rat brain ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGlutamate receptor ionotropic, NMDA 1(Rat)
Cocensys

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50056612BDBM50056612(6-Amino-7-fluoro-5-nitro-1,4-dihydro-quinoxaline-2...)
Affinity DataIC50: 1.10E+4nMAssay Description:Potency for the N-methyl-D-aspartate glutamate receptor 1 glycine site by displacement of [3H]5,7-dichlorokynurenic acid (DCKA) binding in rat brain ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGlutamate receptor ionotropic, NMDA 1(Rat)
Cocensys

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50056619BDBM50056619(4,6,7,8-Tetrahydro-1H-cyclopenta[g]quinoxaline-2,3...)
Affinity DataIC50: 1.50E+4nMAssay Description:Potency for the N-methyl-D-aspartate glutamate receptor 1 glycine site by displacement of [3H]5,7-dichlorokynurenic acid (DCKA) binding in rat brain ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGlutamate receptor ionotropic, NMDA 1(Rat)
Cocensys

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50056607BDBM50056607(1,4-Dihydro-benzo[g]quinoxaline-2,3-dione | CHEMBL...)
Affinity DataIC50: 1.60E+4nMAssay Description:Potency for the N-methyl-D-aspartate glutamate receptor 1 glycine site by displacement of [3H]5,7-dichlorokynurenic acid (DCKA) binding in rat brain ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGlutamate receptor ionotropic, NMDA 1(Rat)
Cocensys

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50056599BDBM50056599(6,7-Dimethoxy-1,4-dihydro-quinoxaline-2,3-dione | ...)
Affinity DataIC50: 1.70E+4nMAssay Description:Potency for the N-methyl-D-aspartate glutamate receptor 1 glycine site by displacement of [3H]5,7-dichlorokynurenic acid (DCKA) binding in rat brain ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGlutamate receptor ionotropic, NMDA 1(Rat)
Cocensys

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50056604BDBM50056604(5-Hydroxy-6,7-dimethoxy-1,4-dihydro-quinoxaline-2,...)
Affinity DataIC50: 1.70E+4nMAssay Description:Potency for the N-methyl-D-aspartate glutamate receptor 1 glycine site by displacement of [3H]5,7-dichlorokynurenic acid (DCKA) binding in rat brain ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGlutamate receptor ionotropic, NMDA 1(Rat)
Cocensys

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50056603BDBM50056603(Acetic acid 6,7-dimethoxy-2,3-dioxo-1,2,3,4-tetrah...)
Affinity DataIC50: 5.30E+4nMAssay Description:Potency for the N-methyl-D-aspartate glutamate receptor 1 glycine site by displacement of [3H]5,7-dichlorokynurenic acid (DCKA) binding in rat brain ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGlutamate receptor ionotropic, NMDA 1(Rat)
Cocensys

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50056609BDBM50056609(5,8-Dihydro-[1,3]dioxolo[4,5-g]quinoxaline-6,7-dio...)
Affinity DataIC50: 1.00E+5nMAssay Description:Potency for the N-methyl-D-aspartate glutamate receptor 1 glycine site by displacement of [3H]5,7-dichlorokynurenic acid (DCKA) binding in rat brain ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGlutamate receptor ionotropic, NMDA 1(Rat)
Cocensys

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50056608BDBM50056608(6,7-Dihydroxy-1,4-dihydro-quinoxaline-2,3-dione | ...)
Affinity DataIC50: 1.00E+5nMAssay Description:Potency for the N-methyl-D-aspartate glutamate receptor 1 glycine site by displacement of [3H]5,7-dichlorokynurenic acid (DCKA) binding in rat brain ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed