Compile Data Set for Download or QSAR
Report error Found 28 Enz. Inhib. hit(s) with all data for entry = 50007431
TargetSterol O-acyltransferase 1(Rat)
Warner-Lambert

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50063243BDBM50063243(N-(2,6-Diisopropyl-phenyl)-2-pyridin-2-yl-malonami...)
Affinity DataIC50: 8nMAssay Description:In vitro Acyl coenzyme A:cholesterol acyltransferase inhibition in hepatic microsomes isolated from cholesterol-fed ratsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetLiver carboxylesterase 1(Rabbit)
Warner-Lambert

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50063239BDBM50063239(N-(2,6-Diisopropyl-phenyl)-2-phenyl-malonamic acid...)
Affinity DataIC50: 10nMAssay Description:Inhibition of Acyl coenzyme A:cholesterol acyltransferase by microsomal LAI assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSterol O-acyltransferase 1(Rat)
Warner-Lambert

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50063239BDBM50063239(N-(2,6-Diisopropyl-phenyl)-2-phenyl-malonamic acid...)
Affinity DataIC50: 10nMAssay Description:In vitro Acyl coenzyme A:cholesterol acyltransferase inhibition in hepatic microsomes isolated from cholesterol-fed ratsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSterol O-acyltransferase 1(Rat)
Warner-Lambert

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50063226BDBM50063226(N-(2,6-Diisopropyl-phenyl)-2-phenyl-malonamic acid...)
Affinity DataIC50: 11nMAssay Description:In vitro Acyl coenzyme A:cholesterol acyltransferase inhibition in hepatic microsomes isolated from cholesterol-fed ratsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSterol O-acyltransferase 1(Rat)
Warner-Lambert

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50063231BDBM50063231(N-(2,6-Diisopropyl-phenyl)-2-phenyl-malonamic acid...)
Affinity DataIC50: 12nMAssay Description:In vitro Acyl coenzyme A:cholesterol acyltransferase inhibition in hepatic microsomes isolated from cholesterol-fed ratsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSterol O-acyltransferase 1(Rat)
Warner-Lambert

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50063236BDBM50063236(N-(2,6-Diisopropyl-phenyl)-2-phenyl-malonamic acid...)
Affinity DataIC50: 12nMAssay Description:In vitro Acyl coenzyme A:cholesterol acyltransferase inhibition in hepatic microsomes isolated from cholesterol-fed ratsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSterol O-acyltransferase 1(Rat)
Warner-Lambert

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50063229BDBM50063229(N-(2,6-Diisopropyl-phenyl)-2-phenyl-malonamic acid...)
Affinity DataIC50: 13nMAssay Description:In vitro Acyl coenzyme A:cholesterol acyltransferase inhibition in hepatic microsomes isolated from cholesterol-fed ratsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSterol O-acyltransferase 1(Rat)
Warner-Lambert

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50063232BDBM50063232(2-Phenyl-N-(2,4,6-trimethoxy-phenyl)-malonamic aci...)
Affinity DataIC50: 13nMAssay Description:In vitro Acyl coenzyme A:cholesterol acyltransferase inhibition in hepatic microsomes isolated from cholesterol-fed ratsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSterol O-acyltransferase 1(Rat)
Warner-Lambert

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50063235BDBM50063235(N-(2,6-Diisopropyl-phenyl)-2-phenyl-malonamic acid...)
Affinity DataIC50: 13nMAssay Description:In vitro Acyl coenzyme A:cholesterol acyltransferase inhibition in hepatic microsomes isolated from cholesterol-fed ratsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSterol O-acyltransferase 1(Rat)
Warner-Lambert

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50063220BDBM50063220(N-(2,6-Diisopropyl-phenyl)-2-phenyl-malonamic acid...)
Affinity DataIC50: 13nMAssay Description:In vitro Acyl coenzyme A:cholesterol acyltransferase inhibition in hepatic microsomes isolated from cholesterol-fed ratsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSterol O-acyltransferase 1(Rat)
Warner-Lambert

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50063221BDBM50063221(N-(2,6-Diisopropyl-phenyl)-2-phenyl-malonamic acid...)
Affinity DataIC50: 16nMAssay Description:In vitro Acyl coenzyme A:cholesterol acyltransferase inhibition in hepatic microsomes isolated from cholesterol-fed ratsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSterol O-acyltransferase 1(Rat)
Warner-Lambert

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50063227BDBM50063227(2-Phenyl-N-(2,4,6-trimethoxy-phenyl)-malonamic aci...)
Affinity DataIC50: 20nMAssay Description:In vitro Acyl coenzyme A:cholesterol acyltransferase inhibition in hepatic microsomes isolated from cholesterol-fed ratsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetLiver carboxylesterase 1(Rabbit)
Warner-Lambert

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50063239BDBM50063239(N-(2,6-Diisopropyl-phenyl)-2-phenyl-malonamic acid...)
Affinity DataIC50: 20nMAssay Description:Inhibition of Acyl coenzyme A:cholesterol acyltransferase by microsomal MAI2 assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSterol O-acyltransferase 1(Rat)
Warner-Lambert

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50063230BDBM50063230(N-(2,6-Diisopropyl-phenyl)-2,2-dimethyl-malonamic ...)
Affinity DataIC50: 21nMAssay Description:In vitro Acyl coenzyme A:cholesterol acyltransferase inhibition in hepatic microsomes isolated from cholesterol-fed ratsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSterol O-acyltransferase 1(Rat)
Warner-Lambert

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50063224BDBM50063224(N-(2,6-Diisopropyl-phenyl)-2-phenyl-malonamic acid...)
Affinity DataIC50: 22nMAssay Description:In vitro Acyl coenzyme A:cholesterol acyltransferase inhibition in hepatic microsomes isolated from cholesterol-fed ratsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSterol O-acyltransferase 1(Rat)
Warner-Lambert

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50063237BDBM50063237(2-Phenyl-N-(2,4,6-trimethoxy-phenyl)-malonamic aci...)
Affinity DataIC50: 30nMAssay Description:In vitro Acyl coenzyme A:cholesterol acyltransferase inhibition in hepatic microsomes isolated from cholesterol-fed ratsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSterol O-acyltransferase 1(Rat)
Warner-Lambert

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50063240BDBM50063240(N-(2,6-Diisopropyl-phenyl)-2-fluoro-malonamic acid...)
Affinity DataIC50: 32nMAssay Description:In vitro Acyl coenzyme A:cholesterol acyltransferase inhibition in hepatic microsomes isolated from cholesterol-fed ratsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSterol O-acyltransferase 1(Rat)
Warner-Lambert

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50063233BDBM50063233(N-(2,6-Diisopropyl-phenyl)-2-phenyl-malonamic acid...)
Affinity DataIC50: 37nMAssay Description:In vitro Acyl coenzyme A:cholesterol acyltransferase inhibition in hepatic microsomes isolated from cholesterol-fed ratsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSterol O-acyltransferase 1(Rat)
Warner-Lambert

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50063234BDBM50063234(N-(2,6-Diisopropyl-phenyl)-2-phenyl-malonamic acid...)
Affinity DataIC50: 40nMAssay Description:In vitro Acyl coenzyme A:cholesterol acyltransferase inhibition in hepatic microsomes isolated from cholesterol-fed ratsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSterol O-acyltransferase 1(Rat)
Warner-Lambert

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50063222BDBM50063222(N-(2,6-Diisopropyl-phenyl)-2-phenyl-malonamic acid...)
Affinity DataIC50: 50nMAssay Description:In vitro Acyl coenzyme A:cholesterol acyltransferase inhibition in hepatic microsomes isolated from cholesterol-fed ratsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSterol O-acyltransferase 1(Rat)
Warner-Lambert

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50063225BDBM50063225(2-Phenyl-N-(2,4,6-triisopropyl-phenyl)-malonamic a...)
Affinity DataIC50: 56nMAssay Description:In vitro Acyl coenzyme A:cholesterol acyltransferase inhibition in hepatic microsomes isolated from cholesterol-fed ratsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSterol O-acyltransferase 1(Rat)
Warner-Lambert

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50063245BDBM50063245(N-(2,6-Diisopropyl-phenyl)-2-phenyl-malonamic acid...)
Affinity DataIC50: 72nMAssay Description:In vitro Acyl coenzyme A:cholesterol acyltransferase inhibition in hepatic microsomes isolated from cholesterol-fed ratsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSterol O-acyltransferase 1(Rat)
Warner-Lambert

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50063238BDBM50063238(2-Pyridin-2-yl-N-(2,4,6-triisopropyl-phenyl)-malon...)
Affinity DataIC50: 180nMAssay Description:In vitro Acyl coenzyme A:cholesterol acyltransferase inhibition in hepatic microsomes isolated from cholesterol-fed ratsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSterol O-acyltransferase 1(Rat)
Warner-Lambert

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50063223BDBM50063223(N-(2,6-Diisopropyl-phenyl)-2-phenyl-malonamic acid...)
Affinity DataIC50: 200nMAssay Description:In vitro Acyl coenzyme A:cholesterol acyltransferase inhibition in hepatic microsomes isolated from cholesterol-fed ratsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSterol O-acyltransferase 1(Rat)
Warner-Lambert

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50063244BDBM50063244(N-(2,6-Diisopropyl-phenyl)-2,2-dimethyl-malonamic ...)
Affinity DataIC50: 1.00E+3nMAssay Description:In vitro Acyl coenzyme A:cholesterol acyltransferase inhibition in hepatic microsomes isolated from cholesterol-fed ratsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSterol O-acyltransferase 1(Rat)
Warner-Lambert

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50063228BDBM50063228(N-(2,6-Diisopropyl-phenyl)-2-fluoro-malonamic acid...)
Affinity DataIC50: 1.00E+3nMAssay Description:In vitro Acyl coenzyme A:cholesterol acyltransferase inhibition in hepatic microsomes isolated from cholesterol-fed ratsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSterol O-acyltransferase 1(Rat)
Warner-Lambert

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50063242BDBM50063242(N-(2,6-Diisopropyl-phenyl)-2-phenyl-malonamic acid...)
Affinity DataIC50: 1.00E+3nMAssay Description:In vitro Acyl coenzyme A:cholesterol acyltransferase inhibition in hepatic microsomes isolated from cholesterol-fed ratsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSterol O-acyltransferase 1(Rat)
Warner-Lambert

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50063241BDBM50063241(N-(2,6-Diisopropyl-phenyl)-2-phenyl-malonamic acid...)
Affinity DataIC50: 5.00E+3nMAssay Description:In vitro Acyl coenzyme A:cholesterol acyltransferase inhibition in hepatic microsomes isolated from cholesterol-fed ratsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed