Compile Data Set for Download or QSAR
Report error Found 165 Enz. Inhib. hit(s) with all data for entry = 410
TargetGag-Pol polyprotein [600-1027,K702N]/[600-1155,K702N](Human immunodeficiency virus type 1)
Boehringer Ingelheim Pharmaceuticals

LigandChemical structure of BindingDB Monomer ID 2104BDBM2104(13-[2-(3-aminophenyl)ethyl]-5-chloro-2-ethyl-9-met...)
Affinity DataIC50: 10nMAssay Description:The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2004
Entry Details Article
PubMed
TargetGag-Pol polyprotein [600-1027,G789A]/[600-1155,G789A](Human immunodeficiency virus type 1)
Boehringer Ingelheim Pharmaceuticals

LigandChemical structure of BindingDB Monomer ID 2104BDBM2104(13-[2-(3-aminophenyl)ethyl]-5-chloro-2-ethyl-9-met...)
Affinity DataIC50: 10nMAssay Description:The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2004
Entry Details Article
PubMed
TargetGag-Pol polyprotein [600-1027,K702N]/[600-1155,K702N](Human immunodeficiency virus type 1)
Boehringer Ingelheim Pharmaceuticals

LigandChemical structure of BindingDB Monomer ID 2113BDBM2113(13-[2-(2-aminopyridin-4-yl)ethyl]-5-chloro-2-ethyl...)
Affinity DataIC50: 10nMAssay Description:The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2004
Entry Details Article
PubMed
TargetGag-Pol polyprotein [600-1027,R876K]/[600-1155](Human immunodeficiency virus type 1)
Boehringer Ingelheim Pharmaceuticals

LigandChemical structure of BindingDB Monomer ID 2113BDBM2113(13-[2-(2-aminopyridin-4-yl)ethyl]-5-chloro-2-ethyl...)
Affinity DataIC50: 20nMAssay Description:The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2004
Entry Details Article
PubMed
TargetGag-Pol polyprotein [600-1027,K702N]/[600-1155,K702N](Human immunodeficiency virus type 1)
Boehringer Ingelheim Pharmaceuticals

LigandChemical structure of BindingDB Monomer ID 2096BDBM2096(2-ethyl-5-fluoro-9-methyl-13-[2-(pyridin-4-yl)ethy...)
Affinity DataIC50: 20nMAssay Description:The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2004
Entry Details Article
PubMed
TargetGag-Pol polyprotein [600-1027,R876K]/[600-1155](Human immunodeficiency virus type 1)
Boehringer Ingelheim Pharmaceuticals

LigandChemical structure of BindingDB Monomer ID 2099BDBM2099(2-ethyl-5-fluoro-9-methyl-13-[2-(naphthalen-2-yl)e...)
Affinity DataIC50: 20nMAssay Description:The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2004
Entry Details Article
PubMed
TargetGag-Pol polyprotein [600-1027,G789A]/[600-1155,G789A](Human immunodeficiency virus type 1)
Boehringer Ingelheim Pharmaceuticals

LigandChemical structure of BindingDB Monomer ID 2113BDBM2113(13-[2-(2-aminopyridin-4-yl)ethyl]-5-chloro-2-ethyl...)
Affinity DataIC50: 30nMAssay Description:The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2004
Entry Details Article
PubMed
TargetGag-Pol polyprotein [600-1027,R876K]/[600-1155](Human immunodeficiency virus type 1)
Boehringer Ingelheim Pharmaceuticals

LigandChemical structure of BindingDB Monomer ID 2081BDBM2081(2-ethyl-9-methyl-13-[2-(pyridin-3-yl)ethyl]-2,4,9,...)
Affinity DataIC50: 30nMAssay Description:The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2004
Entry Details Article
PubMed
TargetGag-Pol polyprotein [600-1027,G789A]/[600-1155,G789A](Human immunodeficiency virus type 1)
Boehringer Ingelheim Pharmaceuticals

LigandChemical structure of BindingDB Monomer ID 2021BDBM2021(2,8-Substituted Dipyridodiazepinone 37 | 2,8-Disub...)
Affinity DataIC50: 30nMAssay Description:The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2004
Entry Details Article
PubMed
TargetGag-Pol polyprotein [600-1027,R876K]/[600-1155](Human immunodeficiency virus type 1)
Boehringer Ingelheim Pharmaceuticals

LigandChemical structure of BindingDB Monomer ID 2088BDBM2088(2-ethyl-9-methyl-13-[2-(2-methylpyridin-4-yl)ethyl...)
Affinity DataIC50: 30nMAssay Description:The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2004
Entry Details Article
PubMed
TargetGag-Pol polyprotein [600-1027,Y780C]/[600-1155,Y780C](Human immunodeficiency virus type 1)
Boehringer Ingelheim Pharmaceuticals

LigandChemical structure of BindingDB Monomer ID 2099BDBM2099(2-ethyl-5-fluoro-9-methyl-13-[2-(naphthalen-2-yl)e...)
Affinity DataIC50: 30nMAssay Description:The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2004
Entry Details Article
PubMed
TargetGag-Pol polyprotein [600-1027,R876K]/[600-1155](Human immunodeficiency virus type 1)
Boehringer Ingelheim Pharmaceuticals

LigandChemical structure of BindingDB Monomer ID 2091BDBM2091(13-[2-(3-aminophenyl)ethyl]-2-ethyl-9-methyl-2,4,9...)
Affinity DataIC50: 40nMAssay Description:The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2004
Entry Details Article
PubMed
TargetGag-Pol polyprotein [600-1027,R876K]/[600-1155](Human immunodeficiency virus type 1)
Boehringer Ingelheim Pharmaceuticals

LigandChemical structure of BindingDB Monomer ID 2084BDBM2084(2-ethyl-9-methyl-13-[2-(1,3-thiazol-2-yl)ethyl]-2,...)
Affinity DataIC50: 40nMAssay Description:The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2004
Entry Details Article
PubMed
TargetGag-Pol polyprotein [600-1027,P835L]/[600-1155,P835L](Human immunodeficiency virus type 1)
Boehringer Ingelheim Pharmaceuticals

LigandChemical structure of BindingDB Monomer ID 2104BDBM2104(13-[2-(3-aminophenyl)ethyl]-5-chloro-2-ethyl-9-met...)
Affinity DataIC50: 40nMAssay Description:The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2004
Entry Details Article
PubMed
TargetGag-Pol polyprotein [600-1027,R876K]/[600-1155](Human immunodeficiency virus type 1)
Boehringer Ingelheim Pharmaceuticals

LigandChemical structure of BindingDB Monomer ID 2096BDBM2096(2-ethyl-5-fluoro-9-methyl-13-[2-(pyridin-4-yl)ethy...)
Affinity DataIC50: 50nMAssay Description:The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2004
Entry Details Article
PubMed
TargetGag-Pol polyprotein [600-1027,R876K]/[600-1155](Human immunodeficiency virus type 1)
Boehringer Ingelheim Pharmaceuticals

LigandChemical structure of BindingDB Monomer ID 2112BDBM2112(2-Chloro-5,11-dihydro-11-ethyl-5-methyl-8-[2-(2-ca...)
Affinity DataIC50: 50nMAssay Description:The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2004
Entry Details Article
PubMed
TargetGag-Pol polyprotein [600-1027,R876K]/[600-1155](Human immunodeficiency virus type 1)
Boehringer Ingelheim Pharmaceuticals

LigandChemical structure of BindingDB Monomer ID 2067BDBM2067(2-ethyl-13-(hydroxymethyl)-9-methyl-2,4,9,15-tetra...)
Affinity DataIC50: 50nMpH: 7.8 T: 2°CAssay Description:The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2004
Entry Details Article
PubMed
TargetGag-Pol polyprotein [600-1027,R876K]/[600-1155](Human immunodeficiency virus type 1)
Boehringer Ingelheim Pharmaceuticals

LigandChemical structure of BindingDB Monomer ID 2076BDBM2076(5,11-Dihydro-11-ethyl-5-methyl-8-(2-phenylethyl)-6...)
Affinity DataIC50: 50nMpH: 7.8 T: 2°CAssay Description:The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2004
Entry Details Article
PubMed
TargetGag-Pol polyprotein [600-1027,P835L]/[600-1155,P835L](Human immunodeficiency virus type 1)
Boehringer Ingelheim Pharmaceuticals

LigandChemical structure of BindingDB Monomer ID 2096BDBM2096(2-ethyl-5-fluoro-9-methyl-13-[2-(pyridin-4-yl)ethy...)
Affinity DataIC50: 50nMAssay Description:The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2004
Entry Details Article
PubMed
TargetGag-Pol polyprotein [600-1027,R876K]/[600-1155](Human immunodeficiency virus type 1)
Boehringer Ingelheim Pharmaceuticals

LigandChemical structure of BindingDB Monomer ID 2022BDBM2022(2,8-Substituted Dipyridodiazepinone 36 | 2,8-Disub...)
Affinity DataIC50: 50nMAssay Description:The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2004
Entry Details Article
PubMed
TargetGag-Pol polyprotein [600-1027,R876K]/[600-1155](Human immunodeficiency virus type 1)
Boehringer Ingelheim Pharmaceuticals

LigandChemical structure of BindingDB Monomer ID 2080BDBM2080(2-ethyl-9-methyl-13-[2-(pyridin-4-yl)ethyl]-2,4,9,...)
Affinity DataIC50: 50nMAssay Description:The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2004
Entry Details Article
PubMed
TargetGag-Pol polyprotein [600-1027,K702N]/[600-1155,K702N](Human immunodeficiency virus type 1)
Boehringer Ingelheim Pharmaceuticals

LigandChemical structure of BindingDB Monomer ID 2022BDBM2022(2,8-Substituted Dipyridodiazepinone 36 | 2,8-Disub...)
Affinity DataIC50: 50nMAssay Description:The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2004
Entry Details Article
PubMed
TargetGag-Pol polyprotein [600-1027,G789A]/[600-1155,G789A](Human immunodeficiency virus type 1)
Boehringer Ingelheim Pharmaceuticals

LigandChemical structure of BindingDB Monomer ID 2096BDBM2096(2-ethyl-5-fluoro-9-methyl-13-[2-(pyridin-4-yl)ethy...)
Affinity DataIC50: 60nMAssay Description:The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2004
Entry Details Article
PubMed
TargetGag-Pol polyprotein [600-1027,R876K]/[600-1155](Human immunodeficiency virus type 1)
Boehringer Ingelheim Pharmaceuticals

LigandChemical structure of BindingDB Monomer ID 2109BDBM2109(5,11-Dihydro-11-ethyl-5-methyl-8-[2-(2-methylpyrid...)
Affinity DataIC50: 60nMAssay Description:The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2004
Entry Details Article
PubMed
TargetGag-Pol polyprotein [600-1027,R876K]/[600-1155](Human immunodeficiency virus type 1)
Boehringer Ingelheim Pharmaceuticals

LigandChemical structure of BindingDB Monomer ID 2090BDBM2090(13-[2-(4-aminophenyl)ethyl]-2-ethyl-9-methyl-2,4,9...)
Affinity DataIC50: 60nMAssay Description:The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2004
Entry Details Article
PubMed
TargetGag-Pol polyprotein [600-1027,R876K]/[600-1155](Human immunodeficiency virus type 1)
Boehringer Ingelheim Pharmaceuticals

LigandChemical structure of BindingDB Monomer ID 2105BDBM2105([3-(2-{5-chloro-2-ethyl-9-methyl-10-oxo-2,4,9,15-t...)
Affinity DataIC50: 60nMAssay Description:The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2004
Entry Details Article
PubMed
TargetGag-Pol polyprotein [600-1027,Y780C]/[600-1155,Y780C](Human immunodeficiency virus type 1)
Boehringer Ingelheim Pharmaceuticals

LigandChemical structure of BindingDB Monomer ID 2091BDBM2091(13-[2-(3-aminophenyl)ethyl]-2-ethyl-9-methyl-2,4,9...)
Affinity DataIC50: 70nMAssay Description:The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2004
Entry Details Article
PubMed
TargetGag-Pol polyprotein [600-1027,Y780C]/[600-1155,Y780C](Human immunodeficiency virus type 1)
Boehringer Ingelheim Pharmaceuticals

LigandChemical structure of BindingDB Monomer ID 2113BDBM2113(13-[2-(2-aminopyridin-4-yl)ethyl]-5-chloro-2-ethyl...)
Affinity DataIC50: 70nMAssay Description:The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2004
Entry Details Article
PubMed
TargetGag-Pol polyprotein [600-1027,Y780C]/[600-1155,Y780C](Human immunodeficiency virus type 1)
Boehringer Ingelheim Pharmaceuticals

LigandChemical structure of BindingDB Monomer ID 2105BDBM2105([3-(2-{5-chloro-2-ethyl-9-methyl-10-oxo-2,4,9,15-t...)
Affinity DataIC50: 80nMAssay Description:The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2004
Entry Details Article
PubMed
TargetGag-Pol polyprotein [600-1027,R876K]/[600-1155](Human immunodeficiency virus type 1)
Boehringer Ingelheim Pharmaceuticals

LigandChemical structure of BindingDB Monomer ID 2092BDBM2092(13-[2-(2-aminophenyl)ethyl]-2-ethyl-9-methyl-2,4,9...)
Affinity DataIC50: 80nMAssay Description:The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2004
Entry Details Article
PubMed
TargetGag-Pol polyprotein [600-1027,Y780C]/[600-1155,Y780C](Human immunodeficiency virus type 1)
Boehringer Ingelheim Pharmaceuticals

LigandChemical structure of BindingDB Monomer ID 2096BDBM2096(2-ethyl-5-fluoro-9-methyl-13-[2-(pyridin-4-yl)ethy...)
Affinity DataIC50: 80nMAssay Description:The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2004
Entry Details Article
PubMed
TargetGag-Pol polyprotein [600-1027,R876K]/[600-1155](Human immunodeficiency virus type 1)
Boehringer Ingelheim Pharmaceuticals

LigandChemical structure of BindingDB Monomer ID 2108BDBM2108(13-[2-(3-azidophenyl)ethyl]-5-chloro-2-ethyl-9-met...)
Affinity DataIC50: 80nMAssay Description:The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2004
Entry Details Article
PubMed
TargetGag-Pol polyprotein [600-1027,R876K]/[600-1155](Human immunodeficiency virus type 1)
Boehringer Ingelheim Pharmaceuticals

LigandChemical structure of BindingDB Monomer ID 2089BDBM2089(2-ethyl-9-methyl-13-[2-(naphthalen-2-yl)ethyl]-2,4...)
Affinity DataIC50: 80nMAssay Description:The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2004
Entry Details Article
PubMed
TargetGag-Pol polyprotein [600-1027,R876K]/[600-1155](Human immunodeficiency virus type 1)
Boehringer Ingelheim Pharmaceuticals

LigandChemical structure of BindingDB Monomer ID 2021BDBM2021(2,8-Substituted Dipyridodiazepinone 37 | 2,8-Disub...)
Affinity DataIC50: 80nMAssay Description:The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2004
Entry Details Article
PubMed
TargetGag-Pol polyprotein [600-1027,P835L]/[600-1155,P835L](Human immunodeficiency virus type 1)
Boehringer Ingelheim Pharmaceuticals

LigandChemical structure of BindingDB Monomer ID 1434BDBM1434(BI-RG-587 | 2-cyclopropyl-7-methyl-2,4,9,15-tetraa...)
Affinity DataIC50: 80nMAssay Description:The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2004
Entry Details Article
PubMed
TargetGag-Pol polyprotein [600-1027,R876K]/[600-1155](Human immunodeficiency virus type 1)
Boehringer Ingelheim Pharmaceuticals

LigandChemical structure of BindingDB Monomer ID 2072BDBM2072(methyl 3-{2-ethyl-9-methyl-10-oxo-2,4,9,15-tetraaz...)
Affinity DataIC50: 90nMpH: 7.8 T: 2°CAssay Description:The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2004
Entry Details Article
PubMed
TargetGag-Pol polyprotein [600-1027,R876K]/[600-1155](Human immunodeficiency virus type 1)
Boehringer Ingelheim Pharmaceuticals

LigandChemical structure of BindingDB Monomer ID 2097BDBM2097(5,11-Dihydro-11-ethyl-2-iodo-8-[2-(4-pyridyl)ethyl...)
Affinity DataIC50: 90nMAssay Description:The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2004
Entry Details Article
PubMed
TargetGag-Pol polyprotein [600-1027,Y780C]/[600-1155,Y780C](Human immunodeficiency virus type 1)
Boehringer Ingelheim Pharmaceuticals

LigandChemical structure of BindingDB Monomer ID 2088BDBM2088(2-ethyl-9-methyl-13-[2-(2-methylpyridin-4-yl)ethyl...)
Affinity DataIC50: 90nMAssay Description:The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2004
Entry Details Article
PubMed
TargetGag-Pol polyprotein [600-1027,V705A]/[600-1155,V705A](Human immunodeficiency virus type 1)
Boehringer Ingelheim Pharmaceuticals

LigandChemical structure of BindingDB Monomer ID 2104BDBM2104(13-[2-(3-aminophenyl)ethyl]-5-chloro-2-ethyl-9-met...)
Affinity DataIC50: 90nMAssay Description:The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2004
Entry Details Article
PubMed
TargetGag-Pol polyprotein [600-1027,R876K]/[600-1155](Human immunodeficiency virus type 1)
Boehringer Ingelheim Pharmaceuticals

LigandChemical structure of BindingDB Monomer ID 1518BDBM1518(CHEMBL37343 | 2-ethyl-9-methyl-2,4,9,15-tetraazatr...)
Affinity DataIC50: 90nMpH: 7.8 T: 2°CAssay Description:The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2004
Entry Details Article
PubMed
TargetGag-Pol polyprotein [600-1027,P835L]/[600-1155,P835L](Human immunodeficiency virus type 1)
Boehringer Ingelheim Pharmaceuticals

LigandChemical structure of BindingDB Monomer ID 2113BDBM2113(13-[2-(2-aminopyridin-4-yl)ethyl]-5-chloro-2-ethyl...)
Affinity DataIC50: 100nMAssay Description:The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2004
Entry Details Article
PubMed
TargetGag-Pol polyprotein [600-1027,R876K]/[600-1155](Human immunodeficiency virus type 1)
Boehringer Ingelheim Pharmaceuticals

LigandChemical structure of BindingDB Monomer ID 2064BDBM2064(13-amino-2-ethyl-9-methyl-2,4,9,15-tetraazatricycl...)
Affinity DataIC50: 100nMpH: 7.8 T: 2°CAssay Description:The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2004
Entry Details Article
PubMed
TargetGag-Pol polyprotein [600-1027,R876K]/[600-1155](Human immunodeficiency virus type 1)
Boehringer Ingelheim Pharmaceuticals

LigandChemical structure of BindingDB Monomer ID 2085BDBM2085(2-ethyl-9-methyl-13-[2-(4-methylphenyl)ethyl]-2,4,...)
Affinity DataIC50: 100nMAssay Description:The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2004
Entry Details Article
PubMed
TargetGag-Pol polyprotein [600-1027,R876K]/[600-1155](Human immunodeficiency virus type 1)
Boehringer Ingelheim Pharmaceuticals

LigandChemical structure of BindingDB Monomer ID 2086BDBM2086(2-ethyl-9-methyl-13-[2-(3-methylphenyl)ethyl]-2,4,...)
Affinity DataIC50: 110nMAssay Description:The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2004
Entry Details Article
PubMed
TargetGag-Pol polyprotein [600-1027,Y780C]/[600-1155,Y780C](Human immunodeficiency virus type 1)
Boehringer Ingelheim Pharmaceuticals

LigandChemical structure of BindingDB Monomer ID 2081BDBM2081(2-ethyl-9-methyl-13-[2-(pyridin-3-yl)ethyl]-2,4,9,...)
Affinity DataIC50: 110nMAssay Description:The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2004
Entry Details Article
PubMed
TargetGag-Pol polyprotein [600-1027,R876K]/[600-1155](Human immunodeficiency virus type 1)
Boehringer Ingelheim Pharmaceuticals

LigandChemical structure of BindingDB Monomer ID 2101BDBM2101(5-chloro-2-ethyl-9-methyl-13-[2-(3-methylphenyl)et...)
Affinity DataIC50: 110nMAssay Description:The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2004
Entry Details Article
PubMed
TargetGag-Pol polyprotein [600-1027,P835L]/[600-1155,P835L](Human immunodeficiency virus type 1)
Boehringer Ingelheim Pharmaceuticals

LigandChemical structure of BindingDB Monomer ID 2021BDBM2021(2,8-Substituted Dipyridodiazepinone 37 | 2,8-Disub...)
Affinity DataIC50: 110nMAssay Description:The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2004
Entry Details Article
PubMed
TargetGag-Pol polyprotein [600-1027,G789A]/[600-1155,G789A](Human immunodeficiency virus type 1)
Boehringer Ingelheim Pharmaceuticals

LigandChemical structure of BindingDB Monomer ID 2022BDBM2022(2,8-Substituted Dipyridodiazepinone 36 | 2,8-Disub...)
Affinity DataIC50: 120nMAssay Description:The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2004
Entry Details Article
PubMed
TargetGag-Pol polyprotein [600-1027,R876K]/[600-1155](Human immunodeficiency virus type 1)
Boehringer Ingelheim Pharmaceuticals

LigandChemical structure of BindingDB Monomer ID 2074BDBM2074(13-benzyl-2-ethyl-9-methyl-2,4,9,15-tetraazatricyc...)
Affinity DataIC50: 120nMpH: 7.8 T: 2°CAssay Description:The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2004
Entry Details Article
PubMed
TargetGag-Pol polyprotein [600-1027,K702N]/[600-1155,K702N](Human immunodeficiency virus type 1)
Boehringer Ingelheim Pharmaceuticals

LigandChemical structure of BindingDB Monomer ID 2021BDBM2021(2,8-Substituted Dipyridodiazepinone 37 | 2,8-Disub...)
Affinity DataIC50: 120nMAssay Description:The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2004
Entry Details Article
PubMed
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