Compile Data Set for Download or QSAR
maximum 50k data
Found 30 Enz. Inhib. hit(s) with all data for entry = 50007725
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)
Pharmacia & Upjohn

Curated by ChEMBL
LigandPNGBDBM50066924(6-Chloro-2-(6-chloro-benzo[1,3]dioxol-5-ylmethylsu...)
Affinity DataIC50:  16nMAssay Description:Inhibition of HIV-1 reverse transcriptase (P236L)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)
Pharmacia & Upjohn

Curated by ChEMBL
LigandPNGBDBM50066930(6-Chloro-2-(3-methyl-benzylsulfanyl)-pyrimidin-4-y...)
Affinity DataIC50:  50nMAssay Description:Inhibition of HIV-1 reverse transcriptase (P236L)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)
Pharmacia & Upjohn

Curated by ChEMBL
LigandPNGBDBM50066931((E)-4-(4-Amino-6-chloro-pyrimidin-2-ylsulfanyl)-bu...)
Affinity DataIC50:  50nMAssay Description:Inhibition of HIV-1 reverse transcriptase (P236L)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)
Pharmacia & Upjohn

Curated by ChEMBL
LigandPNGBDBM50066931((E)-4-(4-Amino-6-chloro-pyrimidin-2-ylsulfanyl)-bu...)
Affinity DataIC50:  60nMAssay Description:Inhibition of HIV-1 reverse transcriptase (wild type)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)
Pharmacia & Upjohn

Curated by ChEMBL
LigandPNGBDBM50066932(6-Chloro-2-(3,4-dichloro-benzylsulfanyl)-pyrimidin...)
Affinity DataIC50:  62nMAssay Description:Inhibition of HIV-1 reverse transcriptase (P236L)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)
Pharmacia & Upjohn

Curated by ChEMBL
LigandPNGBDBM50066934(6-Chloro-2-((E)-3-phenyl-allylsulfanyl)-pyrimidin-...)
Affinity DataIC50:  70nMAssay Description:Inhibition of HIV-1 reverse transcriptase (P236L)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)
Pharmacia & Upjohn

Curated by ChEMBL
LigandPNGBDBM50066937((E)-4-(4-Amino-6-chloro-pyrimidin-2-ylsulfanyl)-bu...)
Affinity DataIC50:  70nMAssay Description:Inhibition of HIV-1 reverse transcriptase (P236L)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)
Pharmacia & Upjohn

Curated by ChEMBL
LigandPNGBDBM50066924(6-Chloro-2-(6-chloro-benzo[1,3]dioxol-5-ylmethylsu...)
Affinity DataIC50:  85nMAssay Description:inhibitory activity against HIV-1 reverse transcriptase (wild typeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)
Pharmacia & Upjohn

Curated by ChEMBL
LigandPNGBDBM50066936(2-(3-Bromo-benzylsulfanyl)-6-chloro-pyrimidin-4-yl...)
Affinity DataIC50:  140nMAssay Description:Inhibition of HIV-1 reverse transcriptase (P236L)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)
Pharmacia & Upjohn

Curated by ChEMBL
LigandPNGBDBM50066927(6-Chloro-2-(naphthalen-2-ylmethylsulfanyl)-pyrimid...)
Affinity DataIC50:  150nMAssay Description:Inhibition of HIV-1 reverse transcriptase (P236L)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)
Pharmacia & Upjohn

Curated by ChEMBL
LigandPNGBDBM50066925(6-Chloro-2-(3-methoxy-benzylsulfanyl)-pyrimidin-4-...)
Affinity DataIC50:  160nMAssay Description:Inhibition of HIV-1 reverse transcriptase (P236L)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)
Pharmacia & Upjohn

Curated by ChEMBL
LigandPNGBDBM1944(BHAP deriv. | CHEMBL593 | DELAVIRDINE MESYLATE | D...)
Affinity DataIC50:  170nMAssay Description:Inhibitory activity against HIV-1 reverse transcriptase (wild type)More data for this Ligand-Target Pair
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)
Pharmacia & Upjohn

Curated by ChEMBL
LigandPNGBDBM50066934(6-Chloro-2-((E)-3-phenyl-allylsulfanyl)-pyrimidin-...)
Affinity DataIC50:  190nMAssay Description:Inhibition of HIV-1 reverse transcriptase (wild type)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)
Pharmacia & Upjohn

Curated by ChEMBL
LigandPNGBDBM50066937((E)-4-(4-Amino-6-chloro-pyrimidin-2-ylsulfanyl)-bu...)
Affinity DataIC50:  200nMAssay Description:Inhibition of HIV-1 reverse transcriptase (wild type)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)
Pharmacia & Upjohn

Curated by ChEMBL
LigandPNGBDBM50066928(3-(4-Amino-6-chloro-pyrimidin-2-ylsulfanylmethyl)-...)
Affinity DataIC50:  230nMAssay Description:Inhibition of HIV-1 reverse transcriptase (P236L)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)
Pharmacia & Upjohn

Curated by ChEMBL
LigandPNGBDBM50066930(6-Chloro-2-(3-methyl-benzylsulfanyl)-pyrimidin-4-y...)
Affinity DataIC50:  280nMAssay Description:Inhibition of HIV-1 reverse transcriptase (wild type)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)
Pharmacia & Upjohn

Curated by ChEMBL
LigandPNGBDBM50066935(2-(Naphthalen-2-ylmethylsulfanyl)-6-trifluoromethy...)
Affinity DataIC50:  280nMAssay Description:Inhibition of HIV-1 reverse transcriptase (wild type)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)
Pharmacia & Upjohn

Curated by ChEMBL
LigandPNGBDBM50066928(3-(4-Amino-6-chloro-pyrimidin-2-ylsulfanylmethyl)-...)
Affinity DataIC50:  330nMAssay Description:Inhibition of HIV-1 reverse transcriptase (wild type)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)
Pharmacia & Upjohn

Curated by ChEMBL
LigandPNGBDBM50066935(2-(Naphthalen-2-ylmethylsulfanyl)-6-trifluoromethy...)
Affinity DataIC50:  430nMAssay Description:Inhibition of HIV-1 reverse transcriptase (P236L)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)
Pharmacia & Upjohn

Curated by ChEMBL
LigandPNGBDBM50066927(6-Chloro-2-(naphthalen-2-ylmethylsulfanyl)-pyrimid...)
Affinity DataIC50:  460nMAssay Description:Inhibition of HIV-1 reverse transcriptase (wild type)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)
Pharmacia & Upjohn

Curated by ChEMBL
LigandPNGBDBM50066932(6-Chloro-2-(3,4-dichloro-benzylsulfanyl)-pyrimidin...)
Affinity DataIC50:  490nMAssay Description:Inhibition of HIV-1 reverse transcriptase (wild type)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)
Pharmacia & Upjohn

Curated by ChEMBL
LigandPNGBDBM50066929(6-Chloro-2-(3,4-dihydro-naphthalen-1-ylmethylsulfa...)
Affinity DataIC50:  600nMAssay Description:Inhibition of HIV-1 reverse transcriptase (P236L)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)
Pharmacia & Upjohn

Curated by ChEMBL
LigandPNGBDBM50066936(2-(3-Bromo-benzylsulfanyl)-6-chloro-pyrimidin-4-yl...)
Affinity DataIC50:  760nMAssay Description:Inhibition of HIV-1 reverse transcriptase (wild type)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)
Pharmacia & Upjohn

Curated by ChEMBL
LigandPNGBDBM50066926((E)-4-(4-Amino-6-chloro-pyrimidin-2-ylsulfanyl)-bu...)
Affinity DataIC50:  930nMAssay Description:Inhibition of HIV-1 reverse transcriptase (P236L)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)
Pharmacia & Upjohn

Curated by ChEMBL
LigandPNGBDBM50066925(6-Chloro-2-(3-methoxy-benzylsulfanyl)-pyrimidin-4-...)
Affinity DataIC50:  980nMAssay Description:Inhibition of HIV-1 reverse transcriptase (wild type)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)
Pharmacia & Upjohn

Curated by ChEMBL
LigandPNGBDBM50066933(2-Benzylsulfanyl-6-chloro-pyrimidin-4-ylamine | CH...)
Affinity DataIC50:  1.47E+3nMAssay Description:Inhibition of HIV-1 reverse transcriptase (P236L)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)
Pharmacia & Upjohn

Curated by ChEMBL
LigandPNGBDBM50066926((E)-4-(4-Amino-6-chloro-pyrimidin-2-ylsulfanyl)-bu...)
Affinity DataIC50:  5.25E+3nMAssay Description:Inhibition of HIV-1 reverse transcriptase (wild type)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)
Pharmacia & Upjohn

Curated by ChEMBL
LigandPNGBDBM50066933(2-Benzylsulfanyl-6-chloro-pyrimidin-4-ylamine | CH...)
Affinity DataIC50:  6.66E+3nMAssay Description:Inhibition of HIV-1 reverse transcriptase (wild type)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)
Pharmacia & Upjohn

Curated by ChEMBL
LigandPNGBDBM1944(BHAP deriv. | CHEMBL593 | DELAVIRDINE MESYLATE | D...)
Affinity DataIC50:  6.66E+3nMAssay Description:Inhibitory activity against HIV-1 reverse transcriptase (P236L)More data for this Ligand-Target Pair
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)
Pharmacia & Upjohn

Curated by ChEMBL
LigandPNGBDBM50066929(6-Chloro-2-(3,4-dihydro-naphthalen-1-ylmethylsulfa...)
Affinity DataIC50:  1.60E+4nMAssay Description:Inhibition of HIV-1 reverse transcriptase (wild type)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed