Compile Data Set for Download or QSAR
Report error Found 7 Enz. Inhib. hit(s) with all data for entry = 50007761
TargetHistamine H3 receptor(Rat)
Freie UniversitäT Berlin

Curated by ChEMBL
LigandPNGBDBM22541(VUF 9153 | N''-[(4-chlorophenyl)methyl]{[3-(1H-imi...)
Affinity DataKi:  0.600nMAssay Description:In vitro antagonist potency at Histamine H3 receptor measured as K+-evoked [3H]histamine release from synaptosomes of rat cerebral cortex.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetHistamine H3 receptor(Rat)
Freie UniversitäT Berlin

Curated by ChEMBL
LigandPNGBDBM50067472(4-[3-(4-Ethynyl-phenoxy)-propyl]-1H-imidazole (FUB...)
Affinity DataKi:  2.30nMAssay Description:In vitro antagonist potency at Histamine H3 receptor measured as K+-evoked [3H]histamine release from synaptosomes of rat cerebral cortex.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetHistamine H3 receptor(Rat)
Freie UniversitäT Berlin

Curated by ChEMBL
LigandPNGBDBM22914(CHEMBL260374 | N-cyclohexyl-4-(1H-imidazol-5-yl)pi...)
Affinity DataKi:  4nMAssay Description:In vitro antagonist potency at Histamine H3 receptor measured as K+-evoked [3H]histamine release from synaptosomes of rat cerebral cortex.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetHistamine H3 receptor(Rat)
Freie UniversitäT Berlin

Curated by ChEMBL
LigandPNGBDBM50067470(4-[3-(4-Prop-1-ynyl-phenoxy)-propyl]-1H-imidazole ...)
Affinity DataKi:  7.5nMAssay Description:In vitro antagonist potency at Histamine H3 receptor measured as K+-evoked [3H]histamine release from synaptosomes of rat cerebral cortex.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetHistamine H3 receptor(Rat)
Freie UniversitäT Berlin

Curated by ChEMBL
LigandPNGBDBM50067473(4-[3-(4-Trimethylsilanylethynyl-phenoxy)-propyl]-1...)
Affinity DataKi:  36nMAssay Description:In vitro antagonist potency at Histamine H3 receptor measured as K+-evoked [3H]histamine release from synaptosomes of rat cerebral cortex.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetHistamine H3 receptor(Rat)
Freie UniversitäT Berlin

Curated by ChEMBL
LigandPNGBDBM50067474(4-{3-[4-(3,3-Dimethyl-but-1-ynyl)-phenoxy]-propyl}...)
Affinity DataKi:  123nMAssay Description:In vitro antagonist potency at Histamine H3 receptor measured as K+-evoked [3H]histamine release from synaptosomes of rat cerebral cortex.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetHistamine H3 receptor(Rat)
Freie UniversitäT Berlin

Curated by ChEMBL
LigandPNGBDBM50067471(4-[3-(4-Pent-1-ynyl-phenoxy)-propyl]-1H-imidazole ...)
Affinity DataKi:  140nMAssay Description:In vitro antagonist potency at Histamine H3 receptor measured as K+-evoked [3H]histamine release from synaptosomes of rat cerebral cortex.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed