Compile Data Set for Download or QSAR
Report error Found 27 Enz. Inhib. hit(s) with all data for entry = 50008032
TargetMatrix metalloproteinase-9(Human)
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50070256((R)-2-((S)-2-Hydroxy-3-mercapto-propyl)-nonanoic a...)
Affinity DataIC50: 0.140nMAssay Description:Inhibition of matrix metalloprotease-9, gelatinase-BMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMatrix metalloproteinase-9(Human)
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50070257((R)-2-(3-Mercapto-2-oxo-propyl)-nonanoic acid ((S)...)
Affinity DataIC50: 0.140nMAssay Description:Inhibition of matrix metalloprotease-9, gelatinase-BMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetInterstitial collagenase(Human)
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50063920(Ro-31-9790 | (R)-N*1*-((S)-2,2-Dimethyl-1-methylca...)
Affinity DataIC50: 5nMAssay Description:Inhibition of matrix metalloprotease-1, Collagenase-1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetInterstitial collagenase(Human)
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50070256((R)-2-((S)-2-Hydroxy-3-mercapto-propyl)-nonanoic a...)
Affinity DataIC50: 5nMAssay Description:Inhibition of matrix metalloprotease-1, Collagenase-1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetStromelysin-1(Human)
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50070257((R)-2-(3-Mercapto-2-oxo-propyl)-nonanoic acid ((S)...)
Affinity DataIC50: 8nMAssay Description:Inhibition of matrix metalloprotease-3, stromelysin-1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMatrix metalloproteinase-9(Human)
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50070253((2R,4S)-4-Hydroxy-2-isobutyl-5-mercapto-pentanoic ...)
Affinity DataIC50: 8nMAssay Description:Inhibition of matrix metalloprotease-9, gelatinase-BMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMatrix metalloproteinase-9(Human)
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50070254((R)-2-Isobutyl-5-mercapto-4-oxo-pentanoic acid ((S...)
Affinity DataIC50: 8nMAssay Description:Inhibition of matrix metalloprotease-9, gelatinase-BMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetStromelysin-1(Human)
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50070256((R)-2-((S)-2-Hydroxy-3-mercapto-propyl)-nonanoic a...)
Affinity DataIC50: 9nMAssay Description:Inhibition of matrix metalloprotease-3, stromelysin-1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetInterstitial collagenase(Human)
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50070257((R)-2-(3-Mercapto-2-oxo-propyl)-nonanoic acid ((S)...)
Affinity DataIC50: 10nMAssay Description:Inhibition of matrix metalloprotease-1, Collagenase-1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetInterstitial collagenase(Human)
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50070253((2R,4S)-4-Hydroxy-2-isobutyl-5-mercapto-pentanoic ...)
Affinity DataIC50: 11nMAssay Description:Inhibition of matrix metalloprotease-1, Collagenase-1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetInterstitial collagenase(Human)
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50070254((R)-2-Isobutyl-5-mercapto-4-oxo-pentanoic acid ((S...)
Affinity DataIC50: 11nMAssay Description:Inhibition of matrix metalloprotease-1, Collagenase-1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMatrix metalloproteinase-9(Human)
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50070251((R)-2-((R)-2-Hydroxy-3-mercapto-propyl)-nonanoic a...)
Affinity DataIC50: 12nMAssay Description:Inhibition of matrix metalloprotease-9, gelatinase-BMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMatrix metalloproteinase-9(Human)
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50063920(Ro-31-9790 | (R)-N*1*-((S)-2,2-Dimethyl-1-methylca...)
Affinity DataIC50: 12nMAssay Description:Inhibition of matrix metalloprotease-9, gelatinase-BMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMatrix metalloproteinase-9(Human)
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50070258((R)-2-(3-Mercapto-2-oxo-propyl)-nonanoic acid [(S)...)
Affinity DataIC50: 20nMAssay Description:Inhibition of matrix metalloprotease-9, gelatinase-BMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMatrix metalloproteinase-9(Human)
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50070255((R)-2-((S)-2-Hydroxy-3-mercapto-propyl)-nonanoic a...)
Affinity DataIC50: 24nMAssay Description:Inhibition of matrix metalloprotease-9, gelatinase-BMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetStromelysin-1(Human)
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50070258((R)-2-(3-Mercapto-2-oxo-propyl)-nonanoic acid [(S)...)
Affinity DataIC50: 36nMAssay Description:Inhibition of matrix metalloprotease-3, stromelysin-1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetStromelysin-1(Human)
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50070255((R)-2-((S)-2-Hydroxy-3-mercapto-propyl)-nonanoic a...)
Affinity DataIC50: 39nMAssay Description:Inhibition of matrix metalloprotease-3, stromelysin-1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetInterstitial collagenase(Human)
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50070252((2R,4R)-4-Hydroxy-2-isobutyl-5-mercapto-pentanoic ...)
Affinity DataIC50: 46nMAssay Description:Inhibition of matrix metalloprotease-1, Collagenase-1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetInterstitial collagenase(Human)
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50070251((R)-2-((R)-2-Hydroxy-3-mercapto-propyl)-nonanoic a...)
Affinity DataIC50: 140nMAssay Description:Inhibition of matrix metalloprotease-1, Collagenase-1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMatrix metalloproteinase-9(Human)
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50070252((2R,4R)-4-Hydroxy-2-isobutyl-5-mercapto-pentanoic ...)
Affinity DataIC50: 250nMAssay Description:Inhibition of matrix metalloprotease-9, gelatinase-BMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetStromelysin-1(Human)
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50070251((R)-2-((R)-2-Hydroxy-3-mercapto-propyl)-nonanoic a...)
Affinity DataIC50: 430nMAssay Description:Inhibition of matrix metalloprotease-3, stromelysin-1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetStromelysin-1(Human)
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50063920(Ro-31-9790 | (R)-N*1*-((S)-2,2-Dimethyl-1-methylca...)
Affinity DataIC50: 470nMAssay Description:Inhibition of matrix metalloprotease-3, stromelysin-1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetStromelysin-1(Human)
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50070253((2R,4S)-4-Hydroxy-2-isobutyl-5-mercapto-pentanoic ...)
Affinity DataIC50: 470nMAssay Description:Inhibition of matrix metalloprotease-3, stromelysin-1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetStromelysin-1(Human)
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50070254((R)-2-Isobutyl-5-mercapto-4-oxo-pentanoic acid ((S...)
Affinity DataIC50: 480nMAssay Description:Inhibition of matrix metalloprotease-3, stromelysin-1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetStromelysin-1(Human)
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50070252((2R,4R)-4-Hydroxy-2-isobutyl-5-mercapto-pentanoic ...)
Affinity DataIC50: 3.70E+3nMAssay Description:Inhibition of matrix metalloprotease-3, stromelysin-1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetInterstitial collagenase(Human)
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50070255((R)-2-((S)-2-Hydroxy-3-mercapto-propyl)-nonanoic a...)
Affinity DataIC50: 4.00E+3nMAssay Description:Inhibition of matrix metalloprotease-1, Collagenase-1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetInterstitial collagenase(Human)
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50070258((R)-2-(3-Mercapto-2-oxo-propyl)-nonanoic acid [(S)...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of matrix metalloprotease-1, Collagenase-1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed