Compile Data Set for Download or QSAR
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Found 27 Enz. Inhib. hit(s) with all data for entry = 50008032
TargetMatrix metalloproteinase-9(Homo sapiens (Human))
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50070257((R)-2-(3-Mercapto-2-oxo-propyl)-nonanoic acid ((S)...)
Affinity DataIC50:  0.140nMAssay Description:Inhibition of matrix metalloproteinase-9, gelatinase-BMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrix metalloproteinase-9(Homo sapiens (Human))
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50070256((R)-2-((S)-2-Hydroxy-3-mercapto-propyl)-nonanoic a...)
Affinity DataIC50:  0.140nMAssay Description:Inhibition of matrix metalloproteinase-9, gelatinase-BMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterstitial collagenase(Homo sapiens (Human))
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50063920((R)-N*1*-((S)-2,2-Dimethyl-1-methylcarbamoyl-propy...)
Affinity DataIC50:  5nMAssay Description:Inhibition of matrix metalloproteinase-1, Collagenase-1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterstitial collagenase(Homo sapiens (Human))
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50070256((R)-2-((S)-2-Hydroxy-3-mercapto-propyl)-nonanoic a...)
Affinity DataIC50:  5nMAssay Description:Inhibition of matrix metalloproteinase-1, Collagenase-1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrix metalloproteinase-9(Homo sapiens (Human))
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50070253((2R,4S)-4-Hydroxy-2-isobutyl-5-mercapto-pentanoic ...)
Affinity DataIC50:  8nMAssay Description:Inhibition of matrix metalloproteinase-9, gelatinase-BMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrix metalloproteinase-9(Homo sapiens (Human))
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50070254((R)-2-Isobutyl-5-mercapto-4-oxo-pentanoic acid ((S...)
Affinity DataIC50:  8nMAssay Description:Inhibition of matrix metalloproteinase-9, gelatinase-BMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetStromelysin-1(Homo sapiens (Human))
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50070257((R)-2-(3-Mercapto-2-oxo-propyl)-nonanoic acid ((S)...)
Affinity DataIC50:  8nMAssay Description:Inhibition of matrix metalloproteinase-3, stromelysin-1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetStromelysin-1(Homo sapiens (Human))
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50070256((R)-2-((S)-2-Hydroxy-3-mercapto-propyl)-nonanoic a...)
Affinity DataIC50:  9nMAssay Description:Inhibition of matrix metalloproteinase-3, stromelysin-1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterstitial collagenase(Homo sapiens (Human))
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50070257((R)-2-(3-Mercapto-2-oxo-propyl)-nonanoic acid ((S)...)
Affinity DataIC50:  10nMAssay Description:Inhibition of matrix metalloproteinase-1, Collagenase-1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterstitial collagenase(Homo sapiens (Human))
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50070253((2R,4S)-4-Hydroxy-2-isobutyl-5-mercapto-pentanoic ...)
Affinity DataIC50:  11nMAssay Description:Inhibition of matrix metalloproteinase-1, Collagenase-1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterstitial collagenase(Homo sapiens (Human))
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50070254((R)-2-Isobutyl-5-mercapto-4-oxo-pentanoic acid ((S...)
Affinity DataIC50:  11nMAssay Description:Inhibition of matrix metalloproteinase-1, Collagenase-1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrix metalloproteinase-9(Homo sapiens (Human))
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50063920((R)-N*1*-((S)-2,2-Dimethyl-1-methylcarbamoyl-propy...)
Affinity DataIC50:  12nMAssay Description:Inhibition of matrix metalloproteinase-9, gelatinase-BMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrix metalloproteinase-9(Homo sapiens (Human))
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50070251((R)-2-((R)-2-Hydroxy-3-mercapto-propyl)-nonanoic a...)
Affinity DataIC50:  12nMAssay Description:Inhibition of matrix metalloproteinase-9, gelatinase-BMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrix metalloproteinase-9(Homo sapiens (Human))
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50070258((R)-2-(3-Mercapto-2-oxo-propyl)-nonanoic acid [(S)...)
Affinity DataIC50:  20nMAssay Description:Inhibition of matrix metalloproteinase-9, gelatinase-BMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrix metalloproteinase-9(Homo sapiens (Human))
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50070255((R)-2-((S)-2-Hydroxy-3-mercapto-propyl)-nonanoic a...)
Affinity DataIC50:  24nMAssay Description:Inhibition of matrix metalloproteinase-9, gelatinase-BMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetStromelysin-1(Homo sapiens (Human))
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50070258((R)-2-(3-Mercapto-2-oxo-propyl)-nonanoic acid [(S)...)
Affinity DataIC50:  36nMAssay Description:Inhibition of matrix metalloproteinase-3, stromelysin-1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetStromelysin-1(Homo sapiens (Human))
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50070255((R)-2-((S)-2-Hydroxy-3-mercapto-propyl)-nonanoic a...)
Affinity DataIC50:  39nMAssay Description:Inhibition of matrix metalloproteinase-3, stromelysin-1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterstitial collagenase(Homo sapiens (Human))
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50070252((2R,4R)-4-Hydroxy-2-isobutyl-5-mercapto-pentanoic ...)
Affinity DataIC50:  46nMAssay Description:Inhibition of matrix metalloproteinase-1, Collagenase-1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterstitial collagenase(Homo sapiens (Human))
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50070251((R)-2-((R)-2-Hydroxy-3-mercapto-propyl)-nonanoic a...)
Affinity DataIC50:  140nMAssay Description:Inhibition of matrix metalloproteinase-1, Collagenase-1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrix metalloproteinase-9(Homo sapiens (Human))
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50070252((2R,4R)-4-Hydroxy-2-isobutyl-5-mercapto-pentanoic ...)
Affinity DataIC50:  250nMAssay Description:Inhibition of matrix metalloproteinase-9, gelatinase-BMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetStromelysin-1(Homo sapiens (Human))
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50070251((R)-2-((R)-2-Hydroxy-3-mercapto-propyl)-nonanoic a...)
Affinity DataIC50:  430nMAssay Description:Inhibition of matrix metalloproteinase-3, stromelysin-1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetStromelysin-1(Homo sapiens (Human))
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50070253((2R,4S)-4-Hydroxy-2-isobutyl-5-mercapto-pentanoic ...)
Affinity DataIC50:  470nMAssay Description:Inhibition of matrix metalloproteinase-3, stromelysin-1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetStromelysin-1(Homo sapiens (Human))
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50063920((R)-N*1*-((S)-2,2-Dimethyl-1-methylcarbamoyl-propy...)
Affinity DataIC50:  470nMAssay Description:Inhibition of matrix metalloproteinase-3, stromelysin-1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetStromelysin-1(Homo sapiens (Human))
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50070254((R)-2-Isobutyl-5-mercapto-4-oxo-pentanoic acid ((S...)
Affinity DataIC50:  480nMAssay Description:Inhibition of matrix metalloproteinase-3, stromelysin-1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetStromelysin-1(Homo sapiens (Human))
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50070252((2R,4R)-4-Hydroxy-2-isobutyl-5-mercapto-pentanoic ...)
Affinity DataIC50:  3.70E+3nMAssay Description:Inhibition of matrix metalloproteinase-3, stromelysin-1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterstitial collagenase(Homo sapiens (Human))
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50070255((R)-2-((S)-2-Hydroxy-3-mercapto-propyl)-nonanoic a...)
Affinity DataIC50: >4.00E+3nMAssay Description:Inhibition of matrix metalloproteinase-1, Collagenase-1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterstitial collagenase(Homo sapiens (Human))
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50070258((R)-2-(3-Mercapto-2-oxo-propyl)-nonanoic acid [(S)...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of matrix metalloproteinase-1, Collagenase-1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed