Compile Data Set for Download or QSAR
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Found 44 Enz. Inhib. hit(s) with all data for entry = 50008247
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)
Glaxowellcome Medicines Research Center

Curated by ChEMBL
LigandPNGBDBM50071777(5-bromo-2-({6-[(4-bromo-2-carboxyphenyl)amino]-6-o...)
Affinity DataIC50:  1.70E+3nMAssay Description:Evaluated for inhibition of HIV-1 reverse transcriptaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)
Glaxowellcome Medicines Research Center

Curated by ChEMBL
LigandPNGBDBM50071776(2-({6-[(2-carboxy-4-chlorophenyl)amino]-6-oxohexan...)
Affinity DataIC50:  1.80E+3nMAssay Description:Evaluated for inhibition of HIV-2 reverse transcriptaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)
Glaxowellcome Medicines Research Center

Curated by ChEMBL
LigandPNGBDBM50071777(5-bromo-2-({6-[(4-bromo-2-carboxyphenyl)amino]-6-o...)
Affinity DataIC50:  3.10E+3nMAssay Description:Evaluated for inhibition of HIV-1 reverse transcriptaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)
Glaxowellcome Medicines Research Center

Curated by ChEMBL
LigandPNGBDBM50071766(5-bromo-2-[5-(4-bromo-2-carboxyphenylcarbamoyl)pen...)
Affinity DataIC50:  3.80E+3nMAssay Description:Evaluated for inhibition of HIV-2 reverse transcriptaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)
Glaxowellcome Medicines Research Center

Curated by ChEMBL
LigandPNGBDBM50071768(2-({6-[(2-carboxy-4-iodophenyl)amino]-6-oxohexanoy...)
Affinity DataIC50:  4.10E+3nMAssay Description:Evaluated for inhibition of HIV-1 reverse transcriptaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)
Glaxowellcome Medicines Research Center

Curated by ChEMBL
LigandPNGBDBM50071765(2-[4-(2-carboxy-4-methoxyphenylcarbamoyl)butylcarb...)
Affinity DataIC50:  4.30E+3nMAssay Description:Evaluated for inhibition of HIV-2 reverse transcriptaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)
Glaxowellcome Medicines Research Center

Curated by ChEMBL
LigandPNGBDBM50071766(5-bromo-2-[5-(4-bromo-2-carboxyphenylcarbamoyl)pen...)
Affinity DataIC50:  4.70E+3nMAssay Description:Evaluated for inhibition of HIV-1 reverse transcriptaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)
Glaxowellcome Medicines Research Center

Curated by ChEMBL
LigandPNGBDBM50071771(5-bromo-2-{[(5-{[(4-bromo-2-carboxyphenyl)amino]ca...)
Affinity DataIC50:  5.50E+3nMAssay Description:Evaluated for inhibition of HIV-2 reverse transcriptaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)
Glaxowellcome Medicines Research Center

Curated by ChEMBL
LigandPNGBDBM50071767(2-({6-[(2-carboxy-4-hydroxyphenyl)amino]-6-oxohexa...)
Affinity DataIC50:  6.70E+3nMAssay Description:Evaluated for inhibition of HIV-1 reverse transcriptaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)
Glaxowellcome Medicines Research Center

Curated by ChEMBL
LigandPNGBDBM50071779(2-[4-(2-carboxy-4-methylsulfanylphenylcarbamoyl)bu...)
Affinity DataIC50:  6.90E+3nMAssay Description:Evaluated for inhibition of HIV-2 reverse transcriptaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)
Glaxowellcome Medicines Research Center

Curated by ChEMBL
LigandPNGBDBM50071762(5-bromo-2-({5-[(4-bromo-2-carboxyphenyl)amino]-5-o...)
Affinity DataIC50:  7.30E+3nMAssay Description:Evaluated for inhibition of HIV-2 reverse transcriptaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)
Glaxowellcome Medicines Research Center

Curated by ChEMBL
LigandPNGBDBM50071761(5-bromo-2-[6-(4-bromo-2-carboxyphenylcarbamoyl)hex...)
Affinity DataIC50:  7.40E+3nMAssay Description:Compound was evaluated for inhibition of HIV-2 reverse transcriptase using rC.dG and [3H]-dGTP as substrates at 100 microg/mlMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)
Glaxowellcome Medicines Research Center

Curated by ChEMBL
LigandPNGBDBM50071778(2-[4-(2-carboxy-4-trifluoromethylphenylcarbamoyl)b...)
Affinity DataIC50:  8.30E+3nMAssay Description:Evaluated for inhibition of HIV-2 reverse transcriptaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)
Glaxowellcome Medicines Research Center

Curated by ChEMBL
LigandPNGBDBM50071768(2-({6-[(2-carboxy-4-iodophenyl)amino]-6-oxohexanoy...)
Affinity DataIC50:  8.50E+3nMAssay Description:Evaluated for inhibition of HIV-1 reverse transcriptaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)
Glaxowellcome Medicines Research Center

Curated by ChEMBL
LigandPNGBDBM50071774(2-({5-[(2-carboxy-4-chlorophenyl)amino]-5-oxopenta...)
Affinity DataIC50:  8.70E+3nMAssay Description:Evaluated for inhibition of HIV-1 reverse transcriptaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)
Glaxowellcome Medicines Research Center

Curated by ChEMBL
LigandPNGBDBM50071776(2-({6-[(2-carboxy-4-chlorophenyl)amino]-6-oxohexan...)
Affinity DataIC50:  8.70E+3nMAssay Description:Evaluated for inhibition of HIV-1 reverse transcriptaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)
Glaxowellcome Medicines Research Center

Curated by ChEMBL
LigandPNGBDBM50071763(2-({6-[(2-carboxyphenyl)amino]-6-oxohexanoyl}amino...)
Affinity DataIC50:  9.00E+3nMAssay Description:Evaluated for inhibition of HIV-2 reverse transcriptaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)
Glaxowellcome Medicines Research Center

Curated by ChEMBL
LigandPNGBDBM50071773(2-[5-(2-carboxy-4-chlorophenylcarbamoyl)pentylcarb...)
Affinity DataIC50:  9.00E+3nMAssay Description:Evaluated for inhibition of HIV-1 reverse transcriptaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)
Glaxowellcome Medicines Research Center

Curated by ChEMBL
LigandPNGBDBM50071773(2-[5-(2-carboxy-4-chlorophenylcarbamoyl)pentylcarb...)
Affinity DataIC50:  9.00E+3nMAssay Description:Evaluated for inhibition of HIV-2 reverse transcriptaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)
Glaxowellcome Medicines Research Center

Curated by ChEMBL
LigandPNGBDBM50071763(2-({6-[(2-carboxyphenyl)amino]-6-oxohexanoyl}amino...)
Affinity DataIC50:  9.00E+3nMAssay Description:Evaluated for inhibition of HIV-2 reverse transcriptaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)
Glaxowellcome Medicines Research Center

Curated by ChEMBL
LigandPNGBDBM50071770(2-[4-(2-carboxy-4-methylphenylcarbamoyl)butylcarbo...)
Affinity DataIC50:  9.20E+3nMAssay Description:Evaluated for inhibition of HIV-2 reverse transcriptaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)
Glaxowellcome Medicines Research Center

Curated by ChEMBL
LigandPNGBDBM50071774(2-({5-[(2-carboxy-4-chlorophenyl)amino]-5-oxopenta...)
Affinity DataIC50:  9.60E+3nMAssay Description:Evaluated for inhibition of HIV-2 reverse transcriptaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)
Glaxowellcome Medicines Research Center

Curated by ChEMBL
LigandPNGBDBM50071762(5-bromo-2-({5-[(4-bromo-2-carboxyphenyl)amino]-5-o...)
Affinity DataIC50:  1.00E+4nMAssay Description:Evaluated for inhibition of HIV-2 reverse transcriptaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)
Glaxowellcome Medicines Research Center

Curated by ChEMBL
LigandPNGBDBM50071765(2-[4-(2-carboxy-4-methoxyphenylcarbamoyl)butylcarb...)
Affinity DataIC50:  1.06E+4nMAssay Description:Evaluated for inhibition of HIV-1 reverse transcriptaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)
Glaxowellcome Medicines Research Center

Curated by ChEMBL
LigandPNGBDBM50071778(2-[4-(2-carboxy-4-trifluoromethylphenylcarbamoyl)b...)
Affinity DataIC50:  1.20E+4nMAssay Description:Evaluated for inhibition of HIV-1 reverse transcriptaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)
Glaxowellcome Medicines Research Center

Curated by ChEMBL
LigandPNGBDBM50071770(2-[4-(2-carboxy-4-methylphenylcarbamoyl)butylcarbo...)
Affinity DataIC50:  1.40E+4nMAssay Description:Evaluated for inhibition of HIV-2 reverse transcriptaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)
Glaxowellcome Medicines Research Center

Curated by ChEMBL
LigandPNGBDBM50071780(5-bromo-2-[(3-{[(4-bromo-2-carboxyphenyl)amino]car...)
Affinity DataIC50:  1.40E+4nMAssay Description:Evaluated for inhibition of HIV-2 reverse transcriptaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)
Glaxowellcome Medicines Research Center

Curated by ChEMBL
LigandPNGBDBM50071760(5-bromo-2-{[(3-{[(4-bromo-2-carboxyphenyl)amino]ca...)
Affinity DataIC50:  1.50E+4nMAssay Description:Evaluated for inhibition of HIV-1 reverse transcriptaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)
Glaxowellcome Medicines Research Center

Curated by ChEMBL
LigandPNGBDBM50071764(5-Bromo-2-[5-(4-bromo-phenylcarbamoyl)-pentanoylam...)
Affinity DataIC50:  1.50E+4nMAssay Description:Evaluated for inhibition of HIV-2 reverse transcriptaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)
Glaxowellcome Medicines Research Center

Curated by ChEMBL
LigandPNGBDBM50071761(5-bromo-2-[6-(4-bromo-2-carboxyphenylcarbamoyl)hex...)
Affinity DataIC50:  1.80E+4nMAssay Description:Compound was evaluated for inhibition of HIV-1 reverse transcriptase using rC.dG and [3H]-dGTP as substrates at 100 ug/mLMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)
Glaxowellcome Medicines Research Center

Curated by ChEMBL
LigandPNGBDBM50071779(2-[4-(2-carboxy-4-methylsulfanylphenylcarbamoyl)bu...)
Affinity DataIC50:  1.90E+4nMAssay Description:Evaluated for inhibition of HIV-1 reverse transcriptaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)
Glaxowellcome Medicines Research Center

Curated by ChEMBL
LigandPNGBDBM50071780(5-bromo-2-[(3-{[(4-bromo-2-carboxyphenyl)amino]car...)
Affinity DataIC50:  1.90E+4nMAssay Description:Evaluated for inhibition of HIV-1 reverse transcriptaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)
Glaxowellcome Medicines Research Center

Curated by ChEMBL
LigandPNGBDBM50071760(5-bromo-2-{[(3-{[(4-bromo-2-carboxyphenyl)amino]ca...)
Affinity DataIC50:  2.10E+4nMAssay Description:Evaluated for inhibition of HIV-1 reverse transcriptaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)
Glaxowellcome Medicines Research Center

Curated by ChEMBL
LigandPNGBDBM50071764(5-Bromo-2-[5-(4-bromo-phenylcarbamoyl)-pentanoylam...)
Affinity DataIC50:  3.20E+4nMAssay Description:Evaluated for inhibition of HIV-2 reverse transcriptaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)
Glaxowellcome Medicines Research Center

Curated by ChEMBL
LigandPNGBDBM50071771(5-bromo-2-{[(5-{[(4-bromo-2-carboxyphenyl)amino]ca...)
Affinity DataIC50:  3.50E+4nMAssay Description:Evaluated for inhibition of HIV-2 reverse transcriptaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)
Glaxowellcome Medicines Research Center

Curated by ChEMBL
LigandPNGBDBM50071772(5-bromo-2-[(2-{[(4-bromo-2-carboxyphenyl)amino]car...)
Affinity DataIC50:  6.60E+4nMAssay Description:Evaluated for inhibition of HIV-1 reverse transcriptaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)
Glaxowellcome Medicines Research Center

Curated by ChEMBL
LigandPNGBDBM50071772(5-bromo-2-[(2-{[(4-bromo-2-carboxyphenyl)amino]car...)
Affinity DataIC50:  6.60E+4nMAssay Description:Evaluated for inhibition of HIV-1 reverse transcriptaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)
Glaxowellcome Medicines Research Center

Curated by ChEMBL
LigandPNGBDBM50071759(2-({6-[(2-carboxy-4-cyanophenyl)amino]-6-oxohexano...)
Affinity DataIC50: >1.00E+5nMAssay Description:Evaluated for inhibition of HIV-1 reverse transcriptaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)
Glaxowellcome Medicines Research Center

Curated by ChEMBL
LigandPNGBDBM50071775(2-[4-(2-carboxy-4-methylcarboxamidophenylcarbamoyl...)
Affinity DataIC50: >1.00E+5nMAssay Description:Compound was evaluated for inhibition of HIV-1 reverse transcriptase using rC.dG and [3H]-dGTP as substrates at 100 microg/mlMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)
Glaxowellcome Medicines Research Center

Curated by ChEMBL
LigandPNGBDBM50071759(2-({6-[(2-carboxy-4-cyanophenyl)amino]-6-oxohexano...)
Affinity DataIC50: >1.00E+5nMAssay Description:Compound was evaluated for inhibition of HIV-2 reverse transcriptase using rC.dG and [3H]-dGTP as substrates at 100 ug/mLMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)
Glaxowellcome Medicines Research Center

Curated by ChEMBL
LigandPNGBDBM50071775(2-[4-(2-carboxy-4-methylcarboxamidophenylcarbamoyl...)
Affinity DataIC50: >1.00E+5nMAssay Description:Evaluated for inhibition of HIV-2 reverse transcriptaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)
Glaxowellcome Medicines Research Center

Curated by ChEMBL
LigandPNGBDBM50071769(2-({6-[(2-carboxy-4-fluorophenyl)amino]-6-oxohexan...)
Affinity DataIC50: >1.20E+5nMAssay Description:Evaluated for inhibition of HIV-1 reverse transcriptaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)
Glaxowellcome Medicines Research Center

Curated by ChEMBL
LigandPNGBDBM50071769(2-({6-[(2-carboxy-4-fluorophenyl)amino]-6-oxohexan...)
Affinity DataIC50: >1.20E+5nMAssay Description:Evaluated for inhibition of HIV-2 reverse transcriptaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)
Glaxowellcome Medicines Research Center

Curated by ChEMBL
LigandPNGBDBM50071767(2-({6-[(2-carboxy-4-hydroxyphenyl)amino]-6-oxohexa...)
Affinity DataIC50:  1.20E+5nMAssay Description:Evaluated for inhibition of HIV-1 reverse transcriptaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed