Compile Data Set for Download or QSAR
Report error Found 42 Enz. Inhib. hit(s) with all data for entry = 50036719
TargetCollagenase 3(Rat)
Procter and Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM8465(CGS 27023 | CHEMBL514138 | hydroxamate analogue 1 ...)
Affinity DataIC50: 4.30nMAssay Description:Inhibition of rat matrix metalloprotease 13More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2012
Entry Details Article
PubMed
TargetMatrix metalloproteinase-9(Human)
Procter and Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM8465(CGS 27023 | CHEMBL514138 | hydroxamate analogue 1 ...)
Affinity DataIC50: 4.30nMAssay Description:Inhibition of human matrix metalloprotease 9More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2012
Entry Details Article
PubMed
TargetNeutrophil collagenase(Human)
Procter and Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM8465(CGS 27023 | CHEMBL514138 | hydroxamate analogue 1 ...)
Affinity DataIC50: 4.40nMAssay Description:Inhibition of human Matrix metalloprotease-8More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2012
Entry Details Article
PubMed
TargetNeutrophil collagenase(Human)
Procter and Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50291979(N-[[2-METHYL-4-HYDROXYCARBAMOYL]BUT-4-YL-N]-BENZYL...)
Affinity DataIC50: 5.30nMAssay Description:Inhibition of human Matrix metalloprotease-8More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2012
Entry Details Article
PubMed
TargetCollagenase 3(Rat)
Procter and Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50291979(N-[[2-METHYL-4-HYDROXYCARBAMOYL]BUT-4-YL-N]-BENZYL...)
Affinity DataIC50: 7.40nMAssay Description:Inhibition of rat matrix metalloprotease 13More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2012
Entry Details Article
PubMed
TargetMatrix metalloproteinase-9(Human)
Procter and Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM8465(CGS 27023 | CHEMBL514138 | hydroxamate analogue 1 ...)
Affinity DataKi:  8nMAssay Description:Inhibition of human matrix metalloprotease 9More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2012
Entry Details Article
PubMed
Target72 kDa type IV collagenase(Human)
Procter and Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM8465(CGS 27023 | CHEMBL514138 | hydroxamate analogue 1 ...)
Affinity DataIC50: 9.10nMAssay Description:Inhibition of human matrix metalloprotease 2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2012
Entry Details Article
PubMed
Target72 kDa type IV collagenase(Human)
Procter and Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50291979(N-[[2-METHYL-4-HYDROXYCARBAMOYL]BUT-4-YL-N]-BENZYL...)
Affinity DataIC50: 13nMAssay Description:Inhibition of human matrix metalloprotease 2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2012
Entry Details Article
PubMed
TargetStromelysin-1(Human)
Procter and Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM8465(CGS 27023 | CHEMBL514138 | hydroxamate analogue 1 ...)
Affinity DataIC50: 17nMAssay Description:Inhibition of human matrix metalloprotease-3More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2012
Entry Details Article
PubMed
Target72 kDa type IV collagenase(Human)
Procter and Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM8465(CGS 27023 | CHEMBL514138 | hydroxamate analogue 1 ...)
Affinity DataKi:  20nMAssay Description:Inhibition of human matrix metalloprotease 2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2012
Entry Details Article
PubMed
TargetMatrix metalloproteinase-9(Human)
Procter and Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50291979(N-[[2-METHYL-4-HYDROXYCARBAMOYL]BUT-4-YL-N]-BENZYL...)
Affinity DataIC50: 21nMAssay Description:Inhibition of human matrix metalloprotease 9More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2012
Entry Details Article
PubMed
TargetInterstitial collagenase(Human)
Procter and Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50291979(N-[[2-METHYL-4-HYDROXYCARBAMOYL]BUT-4-YL-N]-BENZYL...)
Affinity DataIC50: 21nMAssay Description:Inhibition of human matrix metalloprotease 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2012
Entry Details Article
PubMed
TargetStromelysin-1(Human)
Procter and Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50291979(N-[[2-METHYL-4-HYDROXYCARBAMOYL]BUT-4-YL-N]-BENZYL...)
Affinity DataIC50: 24nMAssay Description:Inhibition of human matrix metalloprotease-3More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2012
Entry Details Article
PubMed
TargetInterstitial collagenase(Human)
Procter and Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM8465(CGS 27023 | CHEMBL514138 | hydroxamate analogue 1 ...)
Affinity DataKi:  33nMAssay Description:Inhibition of human matrix metalloprotease 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2012
Entry Details Article
PubMed
TargetMatrix metalloproteinase-9(Human)
Procter and Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50291977((2R)-2-{benzyl[methyl(phenyl)phosphoryl]amino}-N-h...)
Affinity DataIC50: 33nMAssay Description:Inhibition of human matrix metalloprotease 9More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2012
Entry Details Article
PubMed
TargetStromelysin-1(Human)
Procter and Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM8465(CGS 27023 | CHEMBL514138 | hydroxamate analogue 1 ...)
Affinity DataKi:  43nMAssay Description:Inhibition of human matrix metalloprotease-3More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2012
Entry Details Article
PubMed
TargetInterstitial collagenase(Human)
Procter and Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM8465(CGS 27023 | CHEMBL514138 | hydroxamate analogue 1 ...)
Affinity DataIC50: 50nMAssay Description:Inhibition of human matrix metalloprotease 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2012
Entry Details Article
PubMed
TargetStromelysin-1(Human)
Procter and Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50291977((2R)-2-{benzyl[methyl(phenyl)phosphoryl]amino}-N-h...)
Affinity DataIC50: 68nMAssay Description:Inhibition of human matrix metalloprotease-3More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2012
Entry Details Article
PubMed
TargetMatrilysin(Human)
Procter and Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM8465(CGS 27023 | CHEMBL514138 | hydroxamate analogue 1 ...)
Affinity DataIC50: 106nMAssay Description:Inhibition of human matrix metalloprotease 7More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2012
Entry Details Article
PubMed
TargetInterstitial collagenase(Human)
Procter and Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50291977((2R)-2-{benzyl[methyl(phenyl)phosphoryl]amino}-N-h...)
Affinity DataIC50: 120nMAssay Description:Inhibition of human matrix metalloprotease 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2012
Entry Details Article
PubMed
TargetInterstitial collagenase(Human)
Procter and Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50072970((2R)-2-[benzyl(dimethylphosphoryl)amino]-N-hydroxy...)
Affinity DataIC50: 518nMAssay Description:Inhibition of human matrix metalloprotease 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2012
Entry Details Article
PubMed
TargetInterstitial collagenase(Human)
Procter and Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50291981(N-hydroxy-2-[[methyl(phenyl)phosphoryl](2-phenylet...)
Affinity DataIC50: 525nMAssay Description:Inhibition of human matrix metalloprotease 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2012
Entry Details Article
PubMed
TargetInterstitial collagenase(Human)
Procter and Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50072971((2R)-2-{benzyl[ethyl(phenyl)phosphoryl]amino}-N-hy...)
Affinity DataIC50: 608nMAssay Description:Inhibition of human matrix metalloprotease 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2012
Entry Details Article
PubMed
TargetStromelysin-1(Human)
Procter and Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50072971((2R)-2-{benzyl[ethyl(phenyl)phosphoryl]amino}-N-hy...)
Affinity DataIC50: 700nMAssay Description:Inhibition of human matrix metalloprotease-3More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2012
Entry Details Article
PubMed
TargetStromelysin-1(Human)
Procter and Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50291981(N-hydroxy-2-[[methyl(phenyl)phosphoryl](2-phenylet...)
Affinity DataIC50: 700nMAssay Description:Inhibition of human matrix metalloprotease-3More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2012
Entry Details Article
PubMed
TargetInterstitial collagenase(Human)
Procter and Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50072972(N-hydroxy-2-[[diphenylphosphinyl]-(2-phenylethyl)-...)
Affinity DataIC50: 854nMAssay Description:Inhibition of human matrix metalloprotease 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2012
Entry Details Article
PubMed
TargetMatrilysin(Human)
Procter and Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50291979(N-[[2-METHYL-4-HYDROXYCARBAMOYL]BUT-4-YL-N]-BENZYL...)
Affinity DataIC50: 886nMAssay Description:Inhibition of human matrix metalloprotease 7More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2012
Entry Details Article
PubMed
TargetStromelysin-1(Human)
Procter and Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50072970((2R)-2-[benzyl(dimethylphosphoryl)amino]-N-hydroxy...)
Affinity DataIC50: 1.04E+3nMAssay Description:Inhibition of human matrix metalloprotease-3More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2012
Entry Details Article
PubMed
TargetInterstitial collagenase(Human)
Procter and Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50291980((2R)-2-{hexyl[methyl(phenyl)phosphoryl]amino}-N-hy...)
Affinity DataIC50: 1.29E+3nMAssay Description:Inhibition of human matrix metalloprotease 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2012
Entry Details Article
PubMed
TargetStromelysin-1(Human)
Procter and Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50291980((2R)-2-{hexyl[methyl(phenyl)phosphoryl]amino}-N-hy...)
Affinity DataIC50: 1.60E+3nMAssay Description:Inhibition of human matrix metalloprotease-3More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2012
Entry Details Article
PubMed
TargetStromelysin-1(Human)
Procter and Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50072972(N-hydroxy-2-[[diphenylphosphinyl]-(2-phenylethyl)-...)
Affinity DataIC50: 1.75E+3nMAssay Description:Inhibition of human matrix metalloprotease-3More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2012
Entry Details Article
PubMed
TargetMatrilysin(Human)
Procter and Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50291977((2R)-2-{benzyl[methyl(phenyl)phosphoryl]amino}-N-h...)
Affinity DataIC50: 1.86E+3nMAssay Description:Inhibition of human matrix metalloprotease 7More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2012
Entry Details Article
PubMed
TargetInterstitial collagenase(Human)
Procter and Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50369427(CHEMBL367675)
Affinity DataIC50: 2.51E+3nMAssay Description:Inhibition of human matrix metalloprotease 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2012
Entry Details Article
PubMed
TargetStromelysin-1(Human)
Procter and Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50369427(CHEMBL367675)
Affinity DataIC50: 2.55E+3nMAssay Description:Inhibition of human matrix metalloprotease-3More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2012
Entry Details Article
PubMed
TargetInterstitial collagenase(Human)
Procter and Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50072973(N-hydroxy-2-(R)-[[diphenylphosphinyl]benzylamino]-...)
Affinity DataIC50: 6.79E+3nMAssay Description:Inhibition of human matrix metalloprotease 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2012
Entry Details Article
PubMed
TargetInterstitial collagenase(Human)
Procter and Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50369426(CHEMBL368946)
Affinity DataIC50: 7.12E+3nMAssay Description:Inhibition of human matrix metalloprotease 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2012
Entry Details Article
PubMed
TargetStromelysin-1(Human)
Procter and Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50369426(CHEMBL368946)
Affinity DataIC50: 9.17E+3nMAssay Description:Inhibition of human matrix metalloprotease-3More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2012
Entry Details Article
PubMed
TargetStromelysin-1(Human)
Procter and Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50072973(N-hydroxy-2-(R)-[[diphenylphosphinyl]benzylamino]-...)
Affinity DataIC50: 1.03E+4nMAssay Description:Inhibition of human matrix metalloprotease-3More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2012
Entry Details Article
PubMed
TargetInterstitial collagenase(Human)
Procter and Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50369428(CHEMBL366759)
Affinity DataIC50: 3.33E+4nMAssay Description:Inhibition of human matrix metalloprotease 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2012
Entry Details Article
PubMed
TargetStromelysin-1(Human)
Procter and Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50369428(CHEMBL366759)
Affinity DataIC50: 4.93E+4nMAssay Description:Inhibition of human matrix metalloprotease-3More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2012
Entry Details Article
PubMed
TargetInterstitial collagenase(Human)
Procter and Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50291978((2R)-N-hydroxy-4-methyl-2-{[methyl(phenyl)phosphor...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human matrix metalloprotease 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2012
Entry Details Article
PubMed
TargetStromelysin-1(Human)
Procter and Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50291978((2R)-N-hydroxy-4-methyl-2-{[methyl(phenyl)phosphor...)
Affinity DataIC50: 1.31E+5nMAssay Description:Inhibition of human matrix metalloprotease-3More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2012
Entry Details Article
PubMed