Compile Data Set for Download or QSAR
Report error Found 30 Enz. Inhib. hit(s) with all data for entry = 50008434
TargetProthrombin(Human)
Novartis Horsham Research Center

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50073296BDBM50073296(4-((S)-1-Hydroxymethyl-2-phenyl-ethylamino)-pyridi...)
Affinity DataKi:  12nMAssay Description:In vitro binding affinity for human thrombin.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProthrombin(Human)
Novartis Horsham Research Center

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50073308BDBM50073308(4-[(R)-2-(4-Methoxy-phenyl)-1-methyl-ethylamino]-p...)
Affinity DataKi:  15nMAssay Description:In vitro binding affinity for human thrombin.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProthrombin(Human)
Novartis Horsham Research Center

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50073307BDBM50073307(4-((R)-1-Methyl-2-phenyl-ethylamino)-pyridine-3-su...)
Affinity DataKi:  18nMAssay Description:In vitro binding affinity for human thrombin.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProthrombin(Human)
Novartis Horsham Research Center

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50073302BDBM50073302(4-((S)-2-Cyclohexyl-1-hydroxymethyl-ethylamino)-py...)
Affinity DataKi:  18nMAssay Description:In vitro binding affinity for human thrombin.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProthrombin(Human)
Novartis Horsham Research Center

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50073283BDBM50073283(4-[(S)-1-Hydroxymethyl-2-(4-methoxy-phenyl)-ethyla...)
Affinity DataKi:  19nMAssay Description:In vitro binding affinity for human thrombin.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProthrombin(Human)
Novartis Horsham Research Center

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50073297BDBM50073297(4-[(S)-1-Benzyl-2-(4-hydroxy-piperidin-1-yl)-ethyl...)
Affinity DataKi:  19nMAssay Description:In vitro binding affinity for human thrombin.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProthrombin(Human)
Novartis Horsham Research Center

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50073290BDBM50073290(4-{(S)-1-Benzyl-2-[bis-(2-methoxy-ethyl)-amino]-et...)
Affinity DataKi:  19nMAssay Description:In vitro binding affinity for human thrombin.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProthrombin(Human)
Novartis Horsham Research Center

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50073298BDBM50073298(4-((S)-1-Benzyl-2-morpholin-4-yl-ethylamino)-pyrid...)
Affinity DataKi:  22nMAssay Description:In vitro binding affinity for human thrombin.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProthrombin(Human)
Novartis Horsham Research Center

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50073294BDBM50073294(4-((S)-1-Dimethylaminomethyl-2-phenyl-ethylamino)-...)
Affinity DataKi:  24nMAssay Description:In vitro binding affinity for human thrombin.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProthrombin(Human)
Novartis Horsham Research Center

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50073287BDBM50073287(4-[(S)-2-(4-Acetyl-piperazin-1-yl)-1-benzyl-ethyla...)
Affinity DataKi:  24nMAssay Description:In vitro binding affinity for human thrombin.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProthrombin(Human)
Novartis Horsham Research Center

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50073305BDBM50073305(4-((S)-1-Benzyl-2-piperidin-1-yl-ethylamino)-pyrid...)
Affinity DataKi:  25nMAssay Description:In vitro binding affinity for human thrombin.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProthrombin(Human)
Novartis Horsham Research Center

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50073306BDBM50073306(4-((S)-1-Hydroxymethyl-2-phenyl-ethylamino)-pyridi...)
Affinity DataKi:  27nMAssay Description:In vitro binding affinity for human thrombin.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProthrombin(Human)
Novartis Horsham Research Center

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50073299BDBM50073299(4-((S)-2-Cyclohexyl-1-methylaminomethyl-ethylamino...)
Affinity DataKi:  33nMAssay Description:In vitro binding affinity for human thrombin.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProthrombin(Human)
Novartis Horsham Research Center

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50073288BDBM50073288(4-((S)-1-Methylaminomethyl-2-phenyl-ethylamino)-py...)
Affinity DataKi:  35nMAssay Description:In vitro binding affinity for human thrombin.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProthrombin(Human)
Novartis Horsham Research Center

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50073304BDBM50073304(4-((S)-1-Hydroxymethyl-2-phenyl-ethylamino)-pyridi...)
Affinity DataKi:  36nMAssay Description:In vitro binding affinity for human thrombin.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProthrombin(Human)
Novartis Horsham Research Center

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50073295BDBM50073295(4-((S)-1-Hydroxymethyl-2-phenyl-ethylamino)-pyridi...)
Affinity DataKi:  39nMAssay Description:In vitro binding affinity for human thrombin.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProthrombin(Human)
Novartis Horsham Research Center

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50073293BDBM50073293(4-((S)-1-Hydroxymethyl-2-phenyl-ethylamino)-pyridi...)
Affinity DataKi:  41nMAssay Description:In vitro binding affinity for human thrombin.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProthrombin(Human)
Novartis Horsham Research Center

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50073286BDBM50073286(4-((S)-1-Butylaminomethyl-2-phenyl-ethylamino)-pyr...)
Affinity DataKi:  43nMAssay Description:In vitro binding affinity for human thrombin.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProthrombin(Human)
Novartis Horsham Research Center

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50073309BDBM50073309(4-((S)-1-Benzyl-2-diethylamino-ethylamino)-pyridin...)
Affinity DataKi:  45nMAssay Description:In vitro binding affinity for human thrombin.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProthrombin(Human)
Novartis Horsham Research Center

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50073303BDBM50073303(4-((S)-2-Phenyl-1-propylaminomethyl-ethylamino)-py...)
Affinity DataKi:  47nMAssay Description:In vitro binding affinity for human thrombin.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProthrombin(Human)
Novartis Horsham Research Center

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50073300BDBM50073300(4-((S)-1-Benzyl-2-pyrrolidin-1-yl-ethylamino)-pyri...)
Affinity DataKi:  48nMAssay Description:In vitro binding affinity for human thrombin.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProthrombin(Human)
Novartis Horsham Research Center

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50073285BDBM50073285(4-[(S)-2-(3,4-Dimethoxy-phenyl)-1-hydroxymethyl-et...)
Affinity DataKi:  49nMAssay Description:In vitro binding affinity for human thrombin.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProthrombin(Human)
Novartis Horsham Research Center

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50073292BDBM50073292(4-[(S)-1-(2-Hydroxy-ethoxymethyl)-2-phenyl-ethylam...)
Affinity DataKi:  49nMAssay Description:In vitro binding affinity for human thrombin.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProthrombin(Human)
Novartis Horsham Research Center

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50073282BDBM50073282(4-((S)-1-Hydroxymethyl-2-phenyl-ethylamino)-pyridi...)
Affinity DataKi:  65nMAssay Description:In vitro binding affinity for human thrombin.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProthrombin(Human)
Novartis Horsham Research Center

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50073291BDBM50073291(4-{(S)-1-[(2-Hydroxy-ethylamino)-methyl]-2-phenyl-...)
Affinity DataKi:  72nMAssay Description:In vitro binding affinity for human thrombin.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProthrombin(Human)
Novartis Horsham Research Center

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50073284BDBM50073284(4-[(S)-1-Benzyl-2-(3-oxo-piperazin-1-yl)-ethylamin...)
Affinity DataKi:  90nMAssay Description:In vitro binding affinity for human thrombin.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProthrombin(Human)
Novartis Horsham Research Center

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50073289BDBM50073289(4-((S)-1-Ethylaminomethyl-2-phenyl-ethylamino)-pyr...)
Affinity DataKi:  99nMAssay Description:In vitro binding affinity for human thrombin.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProthrombin(Human)
Novartis Horsham Research Center

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50073301BDBM50073301(4-((S)-1-Hydroxymethyl-2-phenyl-ethylamino)-pyridi...)
Affinity DataKi:  100nMAssay Description:In vitro binding affinity for human thrombin.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProthrombin(Human)
Novartis Horsham Research Center

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50073281BDBM50073281(4-((S)-1-Hydroxymethyl-2-phenyl-ethylamino)-pyridi...)
Affinity DataKi:  110nMAssay Description:In vitro binding affinity for human thrombin.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProthrombin(Human)
Novartis Horsham Research Center

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50073280BDBM50073280(4-((S)-1-Hydroxymethyl-2-phenyl-ethylamino)-pyridi...)
Affinity DataKi:  634nMAssay Description:In vitro binding affinity for human thrombin.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed