Compile Data Set for Download or QSAR
Report error Found 247 Enz. Inhib. hit(s) with all data for entry = 540
TargetTransthyretin(Human)
Columbia University

US Patent
LigandChemical structure of BindingDB Monomer ID 249550BDBM249550(US9434727, 148 | US10072016, Compound 148 | US9777...)
Affinity DataIC50: 0.169nMpH: 7.4 T: 2°CAssay Description:Untagged human RBP4 purified from urine of tubular proteinuria patients was purchased from Fitzgerald Industries International. It was biotinylated u...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/21/2018
Entry Details
US Patent

TargetRetinol-binding protein 4(Human)
Columbia University

US Patent
LigandChemical structure of BindingDB Monomer ID 249550BDBM249550(US9434727, 148 | US10072016, Compound 148 | US9777...)
Affinity DataIC50: 1.37nMpH: 7.5Assay Description:Binding of a desired RBP4 antagonist displaces retinol and induces hindrance for RBP4-TTR interaction resulting in the decreased FRET signal (FIG. 7)...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/21/2018
Entry Details
US Patent

TargetRetinol-binding protein 4(Human)
Columbia University

US Patent
LigandChemical structure of BindingDB Monomer ID 249469BDBM249469(US9434727, 68 | US10072016, Compound 68 | US977701...)
Affinity DataIC50: 1.37nMpH: 7.5Assay Description:Binding of a desired RBP4 antagonist displaces retinol and induces hindrance for RBP4-TTR interaction resulting in the decreased FRET signal (FIG. 7)...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/21/2018
Entry Details
US Patent

TargetRetinol-binding protein 4(Human)
Columbia University

US Patent
LigandChemical structure of BindingDB Monomer ID 249485BDBM249485(US9434727, 83 | US10072016, Compound 83 | US977701...)
Affinity DataIC50: 1.37nMpH: 7.5Assay Description:Binding of a desired RBP4 antagonist displaces retinol and induces hindrance for RBP4-TTR interaction resulting in the decreased FRET signal (FIG. 7)...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/21/2018
Entry Details
US Patent

TargetTransthyretin(Human)
Columbia University

US Patent
LigandChemical structure of BindingDB Monomer ID 249474BDBM249474(US9434727, 73 | US9434727, 77 | US10072016, Compou...)
Affinity DataIC50: 1.62nMpH: 7.4 T: 2°CAssay Description:Untagged human RBP4 purified from urine of tubular proteinuria patients was purchased from Fitzgerald Industries International. It was biotinylated u...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/21/2018
Entry Details
US Patent

TargetRetinol-binding protein 4(Human)
Columbia University

US Patent
LigandChemical structure of BindingDB Monomer ID 249474BDBM249474(US9434727, 73 | US9434727, 77 | US10072016, Compou...)
Affinity DataIC50: 2.88nMpH: 7.5Assay Description:Binding of a desired RBP4 antagonist displaces retinol and induces hindrance for RBP4-TTR interaction resulting in the decreased FRET signal (FIG. 7)...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/21/2018
Entry Details
US Patent

TargetRetinol-binding protein 4(Human)
Columbia University

US Patent
LigandChemical structure of BindingDB Monomer ID 249554BDBM249554(US9434727, 152 | US10072016, Compound 152 | US9777...)
Affinity DataIC50: 3.10nMpH: 7.5Assay Description:Binding of a desired RBP4 antagonist displaces retinol and induces hindrance for RBP4-TTR interaction resulting in the decreased FRET signal (FIG. 7)...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/21/2018
Entry Details
US Patent

TargetRetinol-binding protein 4(Human)
Columbia University

US Patent
LigandChemical structure of BindingDB Monomer ID 249522BDBM249522(US9434727, 120 | US10072016, Compound 120 | US9777...)
Affinity DataIC50: 3.45nMpH: 7.5Assay Description:Binding of a desired RBP4 antagonist displaces retinol and induces hindrance for RBP4-TTR interaction resulting in the decreased FRET signal (FIG. 7)...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/21/2018
Entry Details
US Patent

TargetRetinol-binding protein 4(Human)
Columbia University

US Patent
LigandChemical structure of BindingDB Monomer ID 249466BDBM249466(US9434727, 65 | US10072016, Compound 65 | US977701...)
Affinity DataIC50: 4.13nMpH: 7.5Assay Description:Binding of a desired RBP4 antagonist displaces retinol and induces hindrance for RBP4-TTR interaction resulting in the decreased FRET signal (FIG. 7)...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/21/2018
Entry Details
US Patent

TargetRetinol-binding protein 4(Human)
Columbia University

US Patent
LigandChemical structure of BindingDB Monomer ID 249482BDBM249482(US9434727, 80 | US9434727, 81 | US10072016, Compou...)
Affinity DataIC50: 4.33nMpH: 7.5Assay Description:Binding of a desired RBP4 antagonist displaces retinol and induces hindrance for RBP4-TTR interaction resulting in the decreased FRET signal (FIG. 7)...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/21/2018
Entry Details
US Patent

TargetRetinol-binding protein 4(Human)
Columbia University

US Patent
LigandChemical structure of BindingDB Monomer ID 249482BDBM249482(US9434727, 80 | US9434727, 81 | US10072016, Compou...)
Affinity DataIC50: 4.33nMpH: 7.5Assay Description:Binding of a desired RBP4 antagonist displaces retinol and induces hindrance for RBP4-TTR interaction resulting in the decreased FRET signal (FIG. 7)...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/21/2018
Entry Details
US Patent

TargetRetinol-binding protein 4(Human)
Columbia University

US Patent
LigandChemical structure of BindingDB Monomer ID 249482BDBM249482(US9434727, 80 | US9434727, 81 | US10072016, Compou...)
Affinity DataIC50: 4.33nMpH: 7.5Assay Description:Binding of a desired RBP4 antagonist displaces retinol and induces hindrance for RBP4-TTR interaction resulting in the decreased FRET signal (FIG. 7)...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/21/2018
Entry Details
US Patent

TargetRetinol-binding protein 4(Human)
Columbia University

US Patent
LigandChemical structure of BindingDB Monomer ID 249481BDBM249481(US9434727, 79 | US10072016, Compound 79 | US977701...)
Affinity DataIC50: 4.35nMpH: 7.5Assay Description:Binding of a desired RBP4 antagonist displaces retinol and induces hindrance for RBP4-TTR interaction resulting in the decreased FRET signal (FIG. 7)...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/21/2018
Entry Details
US Patent

TargetRetinol-binding protein 4(Human)
Columbia University

US Patent
LigandChemical structure of BindingDB Monomer ID 249464BDBM249464(US9434727, 63 | US10072016, Compound 63 | US977701...)
Affinity DataIC50: 4.46nMpH: 7.5Assay Description:Binding of a desired RBP4 antagonist displaces retinol and induces hindrance for RBP4-TTR interaction resulting in the decreased FRET signal (FIG. 7)...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/21/2018
Entry Details
US Patent

TargetRetinol-binding protein 4(Human)
Columbia University

US Patent
LigandChemical structure of BindingDB Monomer ID 249564BDBM249564(US9434727, 162 | US10072016, Compound 162 | US9777...)
Affinity DataIC50: 4.82nMpH: 7.5Assay Description:Binding of a desired RBP4 antagonist displaces retinol and induces hindrance for RBP4-TTR interaction resulting in the decreased FRET signal (FIG. 7)...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/21/2018
Entry Details
US Patent

TargetRetinol-binding protein 4(Human)
Columbia University

US Patent
LigandChemical structure of BindingDB Monomer ID 249552BDBM249552(US9434727, 150 | US10072016, Compound 150 | US9777...)
Affinity DataIC50: 4.84nMpH: 7.5Assay Description:Binding of a desired RBP4 antagonist displaces retinol and induces hindrance for RBP4-TTR interaction resulting in the decreased FRET signal (FIG. 7)...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/21/2018
Entry Details
US Patent

TargetTransthyretin(Human)
Columbia University

US Patent
LigandChemical structure of BindingDB Monomer ID 249485BDBM249485(US9434727, 83 | US10072016, Compound 83 | US977701...)
Affinity DataIC50: 4.85nMpH: 7.4 T: 2°CAssay Description:Untagged human RBP4 purified from urine of tubular proteinuria patients was purchased from Fitzgerald Industries International. It was biotinylated u...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/21/2018
Entry Details
US Patent

TargetRetinol-binding protein 4(Human)
Columbia University

US Patent
LigandChemical structure of BindingDB Monomer ID 249544BDBM249544(US9434727, 142 | US10072016, Compound 142 | US9777...)
Affinity DataIC50: 4.88nMpH: 7.5Assay Description:Binding of a desired RBP4 antagonist displaces retinol and induces hindrance for RBP4-TTR interaction resulting in the decreased FRET signal (FIG. 7)...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/21/2018
Entry Details
US Patent

TargetRetinol-binding protein 4(Human)
Columbia University

US Patent
LigandChemical structure of BindingDB Monomer ID 249550BDBM249550(US9434727, 148 | US10072016, Compound 148 | US9777...)
Affinity DataIC50: 5.12nMpH: 7.5Assay Description:Binding of a desired RBP4 antagonist displaces retinol and induces hindrance for RBP4-TTR interaction resulting in the decreased FRET signal (FIG. 7)...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/21/2018
Entry Details
US Patent

TargetRetinol-binding protein 4(Human)
Columbia University

US Patent
LigandChemical structure of BindingDB Monomer ID 249543BDBM249543(US9434727, 141 | US10072016, Compound 141 | US9777...)
Affinity DataIC50: 5.24nMpH: 7.5Assay Description:Binding of a desired RBP4 antagonist displaces retinol and induces hindrance for RBP4-TTR interaction resulting in the decreased FRET signal (FIG. 7)...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/21/2018
Entry Details
US Patent

TargetRetinol-binding protein 4(Human)
Columbia University

US Patent
LigandChemical structure of BindingDB Monomer ID 249465BDBM249465(US9434727, 64 | US10072016, Compound 64 | US977701...)
Affinity DataIC50: 5.36nMpH: 7.5Assay Description:Binding of a desired RBP4 antagonist displaces retinol and induces hindrance for RBP4-TTR interaction resulting in the decreased FRET signal (FIG. 7)...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/21/2018
Entry Details
US Patent

TargetRetinol-binding protein 4(Human)
Columbia University

US Patent
LigandChemical structure of BindingDB Monomer ID 249466BDBM249466(US9434727, 65 | US10072016, Compound 65 | US977701...)
Affinity DataIC50: 5.36nMpH: 7.5Assay Description:Binding of a desired RBP4 antagonist displaces retinol and induces hindrance for RBP4-TTR interaction resulting in the decreased FRET signal (FIG. 7)...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/21/2018
Entry Details
US Patent

TargetRetinol-binding protein 4(Human)
Columbia University

US Patent
LigandChemical structure of BindingDB Monomer ID 249466BDBM249466(US9434727, 65 | US10072016, Compound 65 | US977701...)
Affinity DataIC50: 5.36nMpH: 7.5Assay Description:Binding of a desired RBP4 antagonist displaces retinol and induces hindrance for RBP4-TTR interaction resulting in the decreased FRET signal (FIG. 7)...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/21/2018
Entry Details
US Patent

TargetRetinol-binding protein 4(Human)
Columbia University

US Patent
LigandChemical structure of BindingDB Monomer ID 249466BDBM249466(US9434727, 65 | US10072016, Compound 65 | US977701...)
Affinity DataIC50: 5.36nMpH: 7.5Assay Description:Binding of a desired RBP4 antagonist displaces retinol and induces hindrance for RBP4-TTR interaction resulting in the decreased FRET signal (FIG. 7)...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/21/2018
Entry Details
US Patent

TargetRetinol-binding protein 4(Human)
Columbia University

US Patent
LigandChemical structure of BindingDB Monomer ID 249519BDBM249519(US9434727, 117 | US10072016, Compound 117 | US9777...)
Affinity DataIC50: 5.48nMpH: 7.5Assay Description:Binding of a desired RBP4 antagonist displaces retinol and induces hindrance for RBP4-TTR interaction resulting in the decreased FRET signal (FIG. 7)...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/21/2018
Entry Details
US Patent

TargetRetinol-binding protein 4(Human)
Columbia University

US Patent
LigandChemical structure of BindingDB Monomer ID 249563BDBM249563(US9434727, 161 | US10072016, Compound 161 | US9777...)
Affinity DataIC50: 5.74nMpH: 7.5Assay Description:Binding of a desired RBP4 antagonist displaces retinol and induces hindrance for RBP4-TTR interaction resulting in the decreased FRET signal (FIG. 7)...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/21/2018
Entry Details
US Patent

TargetRetinol-binding protein 4(Human)
Columbia University

US Patent
LigandChemical structure of BindingDB Monomer ID 249559BDBM249559(US9434727, 157 | US10072016, Compound 157 | US9777...)
Affinity DataIC50: 5.84nMpH: 7.5Assay Description:Binding of a desired RBP4 antagonist displaces retinol and induces hindrance for RBP4-TTR interaction resulting in the decreased FRET signal (FIG. 7)...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/21/2018
Entry Details
US Patent

TargetRetinol-binding protein 4(Human)
Columbia University

US Patent
LigandChemical structure of BindingDB Monomer ID 249551BDBM249551(US9434727, 149 | US10072016, Compound 149 | US9777...)
Affinity DataIC50: 5.91nMpH: 7.5Assay Description:Binding of a desired RBP4 antagonist displaces retinol and induces hindrance for RBP4-TTR interaction resulting in the decreased FRET signal (FIG. 7)...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/21/2018
Entry Details
US Patent

TargetRetinol-binding protein 4(Human)
Columbia University

US Patent
LigandChemical structure of BindingDB Monomer ID 249482BDBM249482(US9434727, 80 | US9434727, 81 | US10072016, Compou...)
Affinity DataIC50: 6.04nMpH: 7.5Assay Description:Binding of a desired RBP4 antagonist displaces retinol and induces hindrance for RBP4-TTR interaction resulting in the decreased FRET signal (FIG. 7)...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/21/2018
Entry Details
US Patent

TargetTransthyretin(Human)
Columbia University

US Patent
LigandChemical structure of BindingDB Monomer ID 249481BDBM249481(US9434727, 79 | US10072016, Compound 79 | US977701...)
Affinity DataIC50: 6.10nMpH: 7.4 T: 2°CAssay Description:Untagged human RBP4 purified from urine of tubular proteinuria patients was purchased from Fitzgerald Industries International. It was biotinylated u...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/21/2018
Entry Details
US Patent

TargetRetinol-binding protein 4(Human)
Columbia University

US Patent
LigandChemical structure of BindingDB Monomer ID 249546BDBM249546(US9434727, 144 | US10072016, Compound 144 | US9777...)
Affinity DataIC50: 6.17nMpH: 7.5Assay Description:Binding of a desired RBP4 antagonist displaces retinol and induces hindrance for RBP4-TTR interaction resulting in the decreased FRET signal (FIG. 7)...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/21/2018
Entry Details
US Patent

TargetRetinol-binding protein 4(Human)
Columbia University

US Patent
LigandChemical structure of BindingDB Monomer ID 249533BDBM249533(US9434727, 131 | US10072016, Compound 131 | US9777...)
Affinity DataIC50: 6.36nMpH: 7.5Assay Description:Binding of a desired RBP4 antagonist displaces retinol and induces hindrance for RBP4-TTR interaction resulting in the decreased FRET signal (FIG. 7)...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/21/2018
Entry Details
US Patent

TargetRetinol-binding protein 4(Human)
Columbia University

US Patent
LigandChemical structure of BindingDB Monomer ID 249534BDBM249534(US9434727, 132 | US10072016, Compound 132 | US9777...)
Affinity DataIC50: 6.75nMpH: 7.5Assay Description:Binding of a desired RBP4 antagonist displaces retinol and induces hindrance for RBP4-TTR interaction resulting in the decreased FRET signal (FIG. 7)...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/21/2018
Entry Details
US Patent

TargetRetinol-binding protein 4(Human)
Columbia University

US Patent
LigandChemical structure of BindingDB Monomer ID 249513BDBM249513(US9434727, 111 | US10072016, Compound 111 | US9777...)
Affinity DataIC50: 6.89nMpH: 7.5Assay Description:Binding of a desired RBP4 antagonist displaces retinol and induces hindrance for RBP4-TTR interaction resulting in the decreased FRET signal (FIG. 7)...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/21/2018
Entry Details
US Patent

TargetRetinol-binding protein 4(Human)
Columbia University

US Patent
LigandChemical structure of BindingDB Monomer ID 249476BDBM249476(US9434727, 75 | US10072016, Compound 75 | US977701...)
Affinity DataIC50: 6.95nMpH: 7.5Assay Description:Binding of a desired RBP4 antagonist displaces retinol and induces hindrance for RBP4-TTR interaction resulting in the decreased FRET signal (FIG. 7)...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/21/2018
Entry Details
US Patent

TargetRetinol-binding protein 4(Human)
Columbia University

US Patent
LigandChemical structure of BindingDB Monomer ID 249496BDBM249496(US9434727, 94 | US10072016, Compound 94 | US977701...)
Affinity DataIC50: 6.96nMpH: 7.5Assay Description:Binding of a desired RBP4 antagonist displaces retinol and induces hindrance for RBP4-TTR interaction resulting in the decreased FRET signal (FIG. 7)...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/21/2018
Entry Details
US Patent

TargetRetinol-binding protein 4(Human)
Columbia University

US Patent
LigandChemical structure of BindingDB Monomer ID 249493BDBM249493(US9434727, 91 | US10072016, Compound 91 | US977701...)
Affinity DataIC50: 7.06nMpH: 7.5Assay Description:Binding of a desired RBP4 antagonist displaces retinol and induces hindrance for RBP4-TTR interaction resulting in the decreased FRET signal (FIG. 7)...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/21/2018
Entry Details
US Patent

TargetRetinol-binding protein 4(Human)
Columbia University

US Patent
LigandChemical structure of BindingDB Monomer ID 249477BDBM249477(US9434727, 76 | US10072016, Compound 76 | US977701...)
Affinity DataIC50: 7.40nMpH: 7.5Assay Description:Binding of a desired RBP4 antagonist displaces retinol and induces hindrance for RBP4-TTR interaction resulting in the decreased FRET signal (FIG. 7)...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/21/2018
Entry Details
US Patent

TargetTransthyretin(Human)
Columbia University

US Patent
LigandChemical structure of BindingDB Monomer ID 249550BDBM249550(US9434727, 148 | US10072016, Compound 148 | US9777...)
Affinity DataIC50: 7.41nMpH: 7.4 T: 2°CAssay Description:Untagged human RBP4 purified from urine of tubular proteinuria patients was purchased from Fitzgerald Industries International. It was biotinylated u...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/21/2018
Entry Details
US Patent

TargetRetinol-binding protein 4(Human)
Columbia University

US Patent
LigandChemical structure of BindingDB Monomer ID 249503BDBM249503(US9434727, 101 | US10072016, Compound 101 | US9777...)
Affinity DataIC50: 7.44nMpH: 7.5Assay Description:Binding of a desired RBP4 antagonist displaces retinol and induces hindrance for RBP4-TTR interaction resulting in the decreased FRET signal (FIG. 7)...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/21/2018
Entry Details
US Patent

TargetRetinol-binding protein 4(Human)
Columbia University

US Patent
LigandChemical structure of BindingDB Monomer ID 249467BDBM249467(US9434727, 66 | US10072016, Compound 66 | US977701...)
Affinity DataIC50: 7.5nMpH: 7.5Assay Description:Binding of a desired RBP4 antagonist displaces retinol and induces hindrance for RBP4-TTR interaction resulting in the decreased FRET signal (FIG. 7)...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/21/2018
Entry Details
US Patent

TargetRetinol-binding protein 4(Human)
Columbia University

US Patent
LigandChemical structure of BindingDB Monomer ID 249547BDBM249547(US9434727, 145 | US10072016, Compound 145 | US9777...)
Affinity DataIC50: 7.57nMpH: 7.5Assay Description:Binding of a desired RBP4 antagonist displaces retinol and induces hindrance for RBP4-TTR interaction resulting in the decreased FRET signal (FIG. 7)...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/21/2018
Entry Details
US Patent

TargetRetinol-binding protein 4(Human)
Columbia University

US Patent
LigandChemical structure of BindingDB Monomer ID 249497BDBM249497(US9434727, 95 | US10072016, Compound 95 | US977701...)
Affinity DataIC50: 7.78nMpH: 7.5Assay Description:Binding of a desired RBP4 antagonist displaces retinol and induces hindrance for RBP4-TTR interaction resulting in the decreased FRET signal (FIG. 7)...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/21/2018
Entry Details
US Patent

TargetRetinol-binding protein 4(Human)
Columbia University

US Patent
LigandChemical structure of BindingDB Monomer ID 249489BDBM249489(US9434727, 87 | US10072016, Compound 87 | US977701...)
Affinity DataIC50: 7.80nMpH: 7.5Assay Description:Binding of a desired RBP4 antagonist displaces retinol and induces hindrance for RBP4-TTR interaction resulting in the decreased FRET signal (FIG. 7)...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/21/2018
Entry Details
US Patent

TargetRetinol-binding protein 4(Human)
Columbia University

US Patent
LigandChemical structure of BindingDB Monomer ID 249474BDBM249474(US9434727, 73 | US9434727, 77 | US10072016, Compou...)
Affinity DataIC50: 7.96nMpH: 7.5Assay Description:Binding of a desired RBP4 antagonist displaces retinol and induces hindrance for RBP4-TTR interaction resulting in the decreased FRET signal (FIG. 7)...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/21/2018
Entry Details
US Patent

TargetRetinol-binding protein 4(Human)
Columbia University

US Patent
LigandChemical structure of BindingDB Monomer ID 249495BDBM249495(US9434727, 93 | US10072016, Compound 93 | US977701...)
Affinity DataIC50: 8nMpH: 7.5Assay Description:Binding of a desired RBP4 antagonist displaces retinol and induces hindrance for RBP4-TTR interaction resulting in the decreased FRET signal (FIG. 7)...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/21/2018
Entry Details
US Patent

TargetRetinol-binding protein 4(Human)
Columbia University

US Patent
LigandChemical structure of BindingDB Monomer ID 249561BDBM249561(US9434727, 159 | US10072016, Compound 159 | US9777...)
Affinity DataIC50: 8.06nMpH: 7.5Assay Description:Binding of a desired RBP4 antagonist displaces retinol and induces hindrance for RBP4-TTR interaction resulting in the decreased FRET signal (FIG. 7)...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/21/2018
Entry Details
US Patent

TargetRetinol-binding protein 4(Human)
Columbia University

US Patent
LigandChemical structure of BindingDB Monomer ID 249468BDBM249468(US9434727, 67 | US10072016, Compound 67 | US977701...)
Affinity DataIC50: 8.31nMpH: 7.5Assay Description:Binding of a desired RBP4 antagonist displaces retinol and induces hindrance for RBP4-TTR interaction resulting in the decreased FRET signal (FIG. 7)...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/21/2018
Entry Details
US Patent

TargetRetinol-binding protein 4(Human)
Columbia University

US Patent
LigandChemical structure of BindingDB Monomer ID 249474BDBM249474(US9434727, 73 | US9434727, 77 | US10072016, Compou...)
Affinity DataIC50: 8.5nMpH: 7.5Assay Description:Binding of a desired RBP4 antagonist displaces retinol and induces hindrance for RBP4-TTR interaction resulting in the decreased FRET signal (FIG. 7)...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/21/2018
Entry Details
US Patent

TargetRetinol-binding protein 4(Human)
Columbia University

US Patent
LigandChemical structure of BindingDB Monomer ID 249515BDBM249515(US9434727, 113 | US10072016, Compound 113 | US9777...)
Affinity DataIC50: 8.57nMpH: 7.5Assay Description:Binding of a desired RBP4 antagonist displaces retinol and induces hindrance for RBP4-TTR interaction resulting in the decreased FRET signal (FIG. 7)...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/21/2018
Entry Details
US Patent

Displayed 1 to 50 (of 247 total ) | Next | Last >>
Jump to: