Compile Data Set for Download or QSAR
Report error Found 358 Enz. Inhib. hit(s) with all data for entry = 783
TargetMetabotropic glutamate receptor 2(Human)
Sanford-Burnham Medical Research Institute

US Patent
LigandPNGBDBM290486(US10099993, Compound 67)
Affinity DataEC50:  34nMpH: 7.3 T: 2°CAssay Description:Human Embryonic Kidney (HEK-293) cell lines co-expressing rat mGlu receptors 2, 3, 4, 6, 7 or 8 and G protein-coupled inwardly-rectifying potassium (...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2019
Entry Details
US Patent

TargetMetabotropic glutamate receptor 2(Human)
Sanford-Burnham Medical Research Institute

US Patent
LigandPNGBDBM290547(US10099993, Compound 128)
Affinity DataEC50:  35nMpH: 7.3 T: 2°CAssay Description:Human Embryonic Kidney (HEK-293) cell lines co-expressing rat mGlu receptors 2, 3, 4, 6, 7 or 8 and G protein-coupled inwardly-rectifying potassium (...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2019
Entry Details
US Patent

TargetMetabotropic glutamate receptor 2(Human)
Sanford-Burnham Medical Research Institute

US Patent
LigandPNGBDBM50017211(CHEMBL3287695 | US10099993, Compound 44)
Affinity DataEC50:  40nMpH: 7.3 T: 2°CAssay Description:Human Embryonic Kidney (HEK-293) cell lines co-expressing rat mGlu receptors 2, 3, 4, 6, 7 or 8 and G protein-coupled inwardly-rectifying potassium (...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2019
Entry Details
US Patent

TargetMetabotropic glutamate receptor 2(Human)
Sanford-Burnham Medical Research Institute

US Patent
LigandPNGBDBM50017269(CHEMBL3287724 | US10099993, Compound 73)
Affinity DataEC50:  47nMpH: 7.3 T: 2°CAssay Description:Human Embryonic Kidney (HEK-293) cell lines co-expressing rat mGlu receptors 2, 3, 4, 6, 7 or 8 and G protein-coupled inwardly-rectifying potassium (...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2019
Entry Details
US Patent

TargetMetabotropic glutamate receptor 2(Human)
Sanford-Burnham Medical Research Institute

US Patent
LigandPNGBDBM50017283(CHEMBL3287707 | US10099993, Compound 56)
Affinity DataEC50:  50nMpH: 7.3 T: 2°CAssay Description:Human Embryonic Kidney (HEK-293) cell lines co-expressing rat mGlu receptors 2, 3, 4, 6, 7 or 8 and G protein-coupled inwardly-rectifying potassium (...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2019
Entry Details
US Patent

TargetMetabotropic glutamate receptor 2(Human)
Sanford-Burnham Medical Research Institute

US Patent
LigandPNGBDBM50017266(CHEMBL3287720 | US10099993, Compound 69)
Affinity DataEC50:  52nMpH: 7.3 T: 2°CAssay Description:Human Embryonic Kidney (HEK-293) cell lines co-expressing rat mGlu receptors 2, 3, 4, 6, 7 or 8 and G protein-coupled inwardly-rectifying potassium (...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2019
Entry Details
US Patent

TargetMetabotropic glutamate receptor 2(Human)
Sanford-Burnham Medical Research Institute

US Patent
LigandPNGBDBM50017285(CHEMBL3287710 | US10099993, Compound 59)
Affinity DataEC50:  62nMpH: 7.3 T: 2°CAssay Description:Human Embryonic Kidney (HEK-293) cell lines co-expressing rat mGlu receptors 2, 3, 4, 6, 7 or 8 and G protein-coupled inwardly-rectifying potassium (...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2019
Entry Details
US Patent

TargetMetabotropic glutamate receptor 2(Human)
Sanford-Burnham Medical Research Institute

US Patent
LigandPNGBDBM50017267(CHEMBL3287721 | US10099993, Compound 70)
Affinity DataEC50:  74nMpH: 7.3 T: 2°CAssay Description:Human Embryonic Kidney (HEK-293) cell lines co-expressing rat mGlu receptors 2, 3, 4, 6, 7 or 8 and G protein-coupled inwardly-rectifying potassium (...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2019
Entry Details
US Patent

TargetMetabotropic glutamate receptor 2(Human)
Sanford-Burnham Medical Research Institute

US Patent
LigandPNGBDBM50017287(CHEMBL3287712 | US10099993, Compound 61)
Affinity DataEC50:  82nMpH: 7.3 T: 2°CAssay Description:Human Embryonic Kidney (HEK-293) cell lines co-expressing rat mGlu receptors 2, 3, 4, 6, 7 or 8 and G protein-coupled inwardly-rectifying potassium (...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2019
Entry Details
US Patent

TargetMetabotropic glutamate receptor 2(Human)
Sanford-Burnham Medical Research Institute

US Patent
LigandPNGBDBM50017255(CHEMBL3287697 | US10099993, Compound 46)
Affinity DataEC50:  96nMpH: 7.3 T: 2°CAssay Description:Human Embryonic Kidney (HEK-293) cell lines co-expressing rat mGlu receptors 2, 3, 4, 6, 7 or 8 and G protein-coupled inwardly-rectifying potassium (...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2019
Entry Details
US Patent

TargetMetabotropic glutamate receptor 2(Human)
Sanford-Burnham Medical Research Institute

US Patent
LigandPNGBDBM50017252(CHEMBL3287693 | US10099993, Compound 42)
Affinity DataEC50:  102nMpH: 7.3 T: 2°CAssay Description:Human Embryonic Kidney (HEK-293) cell lines co-expressing rat mGlu receptors 2, 3, 4, 6, 7 or 8 and G protein-coupled inwardly-rectifying potassium (...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2019
Entry Details
US Patent

TargetMetabotropic glutamate receptor 2(Human)
Sanford-Burnham Medical Research Institute

US Patent
LigandPNGBDBM50017265(CHEMBL3287719 | US10099993, Compound 68)
Affinity DataEC50:  103nMpH: 7.3 T: 2°CAssay Description:Human Embryonic Kidney (HEK-293) cell lines co-expressing rat mGlu receptors 2, 3, 4, 6, 7 or 8 and G protein-coupled inwardly-rectifying potassium (...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2019
Entry Details
US Patent

TargetMetabotropic glutamate receptor 2(Human)
Sanford-Burnham Medical Research Institute

US Patent
LigandPNGBDBM50017207(CHEMBL3287722 | US10099993, Compound 71)
Affinity DataEC50:  104nMpH: 7.3 T: 2°CAssay Description:Human Embryonic Kidney (HEK-293) cell lines co-expressing rat mGlu receptors 2, 3, 4, 6, 7 or 8 and G protein-coupled inwardly-rectifying potassium (...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2019
Entry Details
US Patent

TargetMetabotropic glutamate receptor 2(Human)
Sanford-Burnham Medical Research Institute

US Patent
LigandPNGBDBM50017288(CHEMBL3287713 | US10099993, Compound 62)
Affinity DataEC50:  113nMpH: 7.3 T: 2°CAssay Description:Human Embryonic Kidney (HEK-293) cell lines co-expressing rat mGlu receptors 2, 3, 4, 6, 7 or 8 and G protein-coupled inwardly-rectifying potassium (...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2019
Entry Details
US Patent

TargetMetabotropic glutamate receptor 2(Human)
Sanford-Burnham Medical Research Institute

US Patent
LigandPNGBDBM50017284(CHEMBL3287708 | US10099993, Compound 57)
Affinity DataEC50:  114nMpH: 7.3 T: 2°CAssay Description:Human Embryonic Kidney (HEK-293) cell lines co-expressing rat mGlu receptors 2, 3, 4, 6, 7 or 8 and G protein-coupled inwardly-rectifying potassium (...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2019
Entry Details
US Patent

TargetMetabotropic glutamate receptor 2(Human)
Sanford-Burnham Medical Research Institute

US Patent
LigandPNGBDBM50017262(CHEMBL3287714 | US10099993, Compound 63)
Affinity DataEC50:  116nMpH: 7.3 T: 2°CAssay Description:Human Embryonic Kidney (HEK-293) cell lines co-expressing rat mGlu receptors 2, 3, 4, 6, 7 or 8 and G protein-coupled inwardly-rectifying potassium (...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2019
Entry Details
US Patent

TargetMetabotropic glutamate receptor 2(Human)
Sanford-Burnham Medical Research Institute

US Patent
LigandPNGBDBM290553(US10099993, Compound 134)
Affinity DataEC50:  118nMpH: 7.3 T: 2°CAssay Description:Human Embryonic Kidney (HEK-293) cell lines co-expressing rat mGlu receptors 2, 3, 4, 6, 7 or 8 and G protein-coupled inwardly-rectifying potassium (...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2019
Entry Details
US Patent

TargetMetabotropic glutamate receptor 2(Human)
Sanford-Burnham Medical Research Institute

US Patent
LigandPNGBDBM50017212(CHEMBL3287671 | US10099993, Compound 20)
Affinity DataEC50:  122nMpH: 7.3 T: 2°CAssay Description:Human Embryonic Kidney (HEK-293) cell lines co-expressing rat mGlu receptors 2, 3, 4, 6, 7 or 8 and G protein-coupled inwardly-rectifying potassium (...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2019
Entry Details
US Patent

TargetMetabotropic glutamate receptor 2(Human)
Sanford-Burnham Medical Research Institute

US Patent
LigandPNGBDBM50017286(CHEMBL3287711 | US10099993, Compound 60)
Affinity DataEC50:  124nMpH: 7.3 T: 2°CAssay Description:Human Embryonic Kidney (HEK-293) cell lines co-expressing rat mGlu receptors 2, 3, 4, 6, 7 or 8 and G protein-coupled inwardly-rectifying potassium (...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2019
Entry Details
US Patent

TargetMetabotropic glutamate receptor 2(Human)
Sanford-Burnham Medical Research Institute

US Patent
LigandPNGBDBM50017270(CHEMBL3287725 | US10099993, Compound 74)
Affinity DataEC50:  136nMpH: 7.3 T: 2°CAssay Description:Human Embryonic Kidney (HEK-293) cell lines co-expressing rat mGlu receptors 2, 3, 4, 6, 7 or 8 and G protein-coupled inwardly-rectifying potassium (...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2019
Entry Details
US Patent

TargetMetabotropic glutamate receptor 2(Human)
Sanford-Burnham Medical Research Institute

US Patent
LigandPNGBDBM290549(US10099993, Compound 130)
Affinity DataEC50:  142nMpH: 7.3 T: 2°CAssay Description:Human Embryonic Kidney (HEK-293) cell lines co-expressing rat mGlu receptors 2, 3, 4, 6, 7 or 8 and G protein-coupled inwardly-rectifying potassium (...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2019
Entry Details
US Patent

TargetMetabotropic glutamate receptor 2(Human)
Sanford-Burnham Medical Research Institute

US Patent
LigandPNGBDBM50017289(CHEMBL3287715 | US10099993, Compound 64)
Affinity DataEC50:  149nMpH: 7.3 T: 2°CAssay Description:Human Embryonic Kidney (HEK-293) cell lines co-expressing rat mGlu receptors 2, 3, 4, 6, 7 or 8 and G protein-coupled inwardly-rectifying potassium (...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2019
Entry Details
US Patent

TargetMetabotropic glutamate receptor 2(Human)
Sanford-Burnham Medical Research Institute

US Patent
LigandPNGBDBM50017243(CHEMBL3287683 | US10099993, Compound 32)
Affinity DataEC50:  151nMpH: 7.3 T: 2°CAssay Description:Human Embryonic Kidney (HEK-293) cell lines co-expressing rat mGlu receptors 2, 3, 4, 6, 7 or 8 and G protein-coupled inwardly-rectifying potassium (...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2019
Entry Details
US Patent

TargetMetabotropic glutamate receptor 3(Human)
Sanford-Burnham Medical Research Institute

US Patent
LigandPNGBDBM50017268(CHEMBL3287723 | US10099993, Compound 96)
Affinity DataEC50:  151nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2019
Entry Details
US Patent

TargetMetabotropic glutamate receptor 2(Human)
Sanford-Burnham Medical Research Institute

US Patent
LigandPNGBDBM50017246(CHEMBL3287687 | US10099993, Compound 36)
Affinity DataEC50:  153nMpH: 7.3 T: 2°CAssay Description:Human Embryonic Kidney (HEK-293) cell lines co-expressing rat mGlu receptors 2, 3, 4, 6, 7 or 8 and G protein-coupled inwardly-rectifying potassium (...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2019
Entry Details
US Patent

TargetMetabotropic glutamate receptor 2(Human)
Sanford-Burnham Medical Research Institute

US Patent
LigandPNGBDBM50017259(CHEMBL3287701 | US10099993, Compound 50)
Affinity DataEC50:  155nMpH: 7.3 T: 2°CAssay Description:Human Embryonic Kidney (HEK-293) cell lines co-expressing rat mGlu receptors 2, 3, 4, 6, 7 or 8 and G protein-coupled inwardly-rectifying potassium (...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2019
Entry Details
US Patent

TargetMetabotropic glutamate receptor 3(Human)
Sanford-Burnham Medical Research Institute

US Patent
LigandPNGBDBM290572(US10099993, Compound 153)
Affinity DataEC50:  158nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2019
Entry Details
US Patent

TargetMetabotropic glutamate receptor 2(Human)
Sanford-Burnham Medical Research Institute

US Patent
LigandPNGBDBM290579(US10099993, Compound 160)
Affinity DataEC50:  159nMpH: 7.3 T: 2°CAssay Description:Human Embryonic Kidney (HEK-293) cell lines co-expressing rat mGlu receptors 2, 3, 4, 6, 7 or 8 and G protein-coupled inwardly-rectifying potassium (...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2019
Entry Details
US Patent

TargetMetabotropic glutamate receptor 2(Human)
Sanford-Burnham Medical Research Institute

US Patent
LigandPNGBDBM50017279(CHEMBL3287703 | US10099993, Compound 52)
Affinity DataEC50:  161nMpH: 7.3 T: 2°CAssay Description:Human Embryonic Kidney (HEK-293) cell lines co-expressing rat mGlu receptors 2, 3, 4, 6, 7 or 8 and G protein-coupled inwardly-rectifying potassium (...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2019
Entry Details
US Patent

TargetMetabotropic glutamate receptor 2(Human)
Sanford-Burnham Medical Research Institute

US Patent
LigandPNGBDBM50017261(CHEMBL3287709 | US10099993, Compound 58)
Affinity DataEC50:  162nMpH: 7.3 T: 2°CAssay Description:Human Embryonic Kidney (HEK-293) cell lines co-expressing rat mGlu receptors 2, 3, 4, 6, 7 or 8 and G protein-coupled inwardly-rectifying potassium (...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2019
Entry Details
US Patent

TargetMetabotropic glutamate receptor 2(Human)
Sanford-Burnham Medical Research Institute

US Patent
LigandPNGBDBM50017263(CHEMBL3287716 | US10099993, Compound 65)
Affinity DataEC50:  171nMpH: 7.3 T: 2°CAssay Description:Human Embryonic Kidney (HEK-293) cell lines co-expressing rat mGlu receptors 2, 3, 4, 6, 7 or 8 and G protein-coupled inwardly-rectifying potassium (...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2019
Entry Details
US Patent

TargetMetabotropic glutamate receptor 2(Human)
Sanford-Burnham Medical Research Institute

US Patent
LigandPNGBDBM50017257(CHEMBL3287699 | US10099993, Compound 48)
Affinity DataEC50:  173nMpH: 7.3 T: 2°CAssay Description:Human Embryonic Kidney (HEK-293) cell lines co-expressing rat mGlu receptors 2, 3, 4, 6, 7 or 8 and G protein-coupled inwardly-rectifying potassium (...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2019
Entry Details
US Patent

TargetMetabotropic glutamate receptor 2(Human)
Sanford-Burnham Medical Research Institute

US Patent
LigandPNGBDBM290556(US10099993, Compound 137)
Affinity DataEC50:  181nMpH: 7.3 T: 2°CAssay Description:Human Embryonic Kidney (HEK-293) cell lines co-expressing rat mGlu receptors 2, 3, 4, 6, 7 or 8 and G protein-coupled inwardly-rectifying potassium (...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2019
Entry Details
US Patent

TargetMetabotropic glutamate receptor 2(Human)
Sanford-Burnham Medical Research Institute

US Patent
LigandPNGBDBM50017268(CHEMBL3287723 | US10099993, Compound 96)
Affinity DataEC50:  184nMpH: 7.3 T: 2°CAssay Description:Human Embryonic Kidney (HEK-293) cell lines co-expressing rat mGlu receptors 2, 3, 4, 6, 7 or 8 and G protein-coupled inwardly-rectifying potassium (...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2019
Entry Details
US Patent

TargetMetabotropic glutamate receptor 2(Human)
Sanford-Burnham Medical Research Institute

US Patent
LigandPNGBDBM290459(US10099993, Compound 40)
Affinity DataEC50:  192nMpH: 7.3 T: 2°CAssay Description:Human Embryonic Kidney (HEK-293) cell lines co-expressing rat mGlu receptors 2, 3, 4, 6, 7 or 8 and G protein-coupled inwardly-rectifying potassium (...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2019
Entry Details
US Patent

TargetMetabotropic glutamate receptor 2(Human)
Sanford-Burnham Medical Research Institute

US Patent
LigandPNGBDBM50017281(CHEMBL3287705 | US10099993, Compound 54)
Affinity DataEC50:  200nMpH: 7.3 T: 2°CAssay Description:Human Embryonic Kidney (HEK-293) cell lines co-expressing rat mGlu receptors 2, 3, 4, 6, 7 or 8 and G protein-coupled inwardly-rectifying potassium (...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2019
Entry Details
US Patent

TargetMetabotropic glutamate receptor 3(Human)
Sanford-Burnham Medical Research Institute

US Patent
LigandPNGBDBM290568(US10099993, Compound 149)
Affinity DataEC50:  203nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2019
Entry Details
US Patent

TargetMetabotropic glutamate receptor 2(Human)
Sanford-Burnham Medical Research Institute

US Patent
LigandPNGBDBM290554(US10099993, Compound 135)
Affinity DataEC50:  208nMpH: 7.3 T: 2°CAssay Description:Human Embryonic Kidney (HEK-293) cell lines co-expressing rat mGlu receptors 2, 3, 4, 6, 7 or 8 and G protein-coupled inwardly-rectifying potassium (...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2019
Entry Details
US Patent

TargetMetabotropic glutamate receptor 2(Human)
Sanford-Burnham Medical Research Institute

US Patent
LigandPNGBDBM50017271(CHEMBL3287726 | US10099993, Compound 75)
Affinity DataEC50:  208nMpH: 7.3 T: 2°CAssay Description:Human Embryonic Kidney (HEK-293) cell lines co-expressing rat mGlu receptors 2, 3, 4, 6, 7 or 8 and G protein-coupled inwardly-rectifying potassium (...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2019
Entry Details
US Patent

TargetMetabotropic glutamate receptor 2(Human)
Sanford-Burnham Medical Research Institute

US Patent
LigandPNGBDBM290572(US10099993, Compound 153)
Affinity DataEC50:  209nMpH: 7.3 T: 2°CAssay Description:Human Embryonic Kidney (HEK-293) cell lines co-expressing rat mGlu receptors 2, 3, 4, 6, 7 or 8 and G protein-coupled inwardly-rectifying potassium (...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2019
Entry Details
US Patent

TargetMetabotropic glutamate receptor 2(Human)
Sanford-Burnham Medical Research Institute

US Patent
LigandPNGBDBM290546(US10099993, Compound 127)
Affinity DataEC50:  219nMpH: 7.3 T: 2°CAssay Description:Human Embryonic Kidney (HEK-293) cell lines co-expressing rat mGlu receptors 2, 3, 4, 6, 7 or 8 and G protein-coupled inwardly-rectifying potassium (...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2019
Entry Details
US Patent

TargetMetabotropic glutamate receptor 2(Human)
Sanford-Burnham Medical Research Institute

US Patent
LigandPNGBDBM50017227(CHEMBL3287675 | US10099993, Compound 24)
Affinity DataEC50:  222nMpH: 7.3 T: 2°CAssay Description:Human Embryonic Kidney (HEK-293) cell lines co-expressing rat mGlu receptors 2, 3, 4, 6, 7 or 8 and G protein-coupled inwardly-rectifying potassium (...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2019
Entry Details
US Patent

TargetMetabotropic glutamate receptor 2(Human)
Sanford-Burnham Medical Research Institute

US Patent
LigandPNGBDBM290550(US10099993, Compound 131)
Affinity DataEC50:  222nMpH: 7.3 T: 2°CAssay Description:Human Embryonic Kidney (HEK-293) cell lines co-expressing rat mGlu receptors 2, 3, 4, 6, 7 or 8 and G protein-coupled inwardly-rectifying potassium (...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2019
Entry Details
US Patent

TargetMetabotropic glutamate receptor 2(Human)
Sanford-Burnham Medical Research Institute

US Patent
LigandPNGBDBM290464(US10099993, Compound 45)
Affinity DataEC50:  228nMpH: 7.3 T: 2°CAssay Description:Human Embryonic Kidney (HEK-293) cell lines co-expressing rat mGlu receptors 2, 3, 4, 6, 7 or 8 and G protein-coupled inwardly-rectifying potassium (...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2019
Entry Details
US Patent

TargetMetabotropic glutamate receptor 2(Human)
Sanford-Burnham Medical Research Institute

US Patent
LigandPNGBDBM290568(US10099993, Compound 149)
Affinity DataEC50:  230nMpH: 7.3 T: 2°CAssay Description:Human Embryonic Kidney (HEK-293) cell lines co-expressing rat mGlu receptors 2, 3, 4, 6, 7 or 8 and G protein-coupled inwardly-rectifying potassium (...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2019
Entry Details
US Patent

TargetMetabotropic glutamate receptor 2(Human)
Sanford-Burnham Medical Research Institute

US Patent
LigandPNGBDBM290563(US10099993, Compound 144)
Affinity DataEC50:  232nMpH: 7.3 T: 2°CAssay Description:Human Embryonic Kidney (HEK-293) cell lines co-expressing rat mGlu receptors 2, 3, 4, 6, 7 or 8 and G protein-coupled inwardly-rectifying potassium (...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2019
Entry Details
US Patent

TargetMetabotropic glutamate receptor 2(Human)
Sanford-Burnham Medical Research Institute

US Patent
LigandPNGBDBM50017290(CHEMBL3287717 | US10099993, Compound 66)
Affinity DataEC50:  234nMpH: 7.3 T: 2°CAssay Description:Human Embryonic Kidney (HEK-293) cell lines co-expressing rat mGlu receptors 2, 3, 4, 6, 7 or 8 and G protein-coupled inwardly-rectifying potassium (...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2019
Entry Details
US Patent

TargetMetabotropic glutamate receptor 2(Human)
Sanford-Burnham Medical Research Institute

US Patent
LigandPNGBDBM50017256(CHEMBL3287698 | US10099993, Compound 47)
Affinity DataEC50:  237nMpH: 7.3 T: 2°CAssay Description:Human Embryonic Kidney (HEK-293) cell lines co-expressing rat mGlu receptors 2, 3, 4, 6, 7 or 8 and G protein-coupled inwardly-rectifying potassium (...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2019
Entry Details
US Patent

TargetMetabotropic glutamate receptor 2(Human)
Sanford-Burnham Medical Research Institute

US Patent
LigandPNGBDBM290544(US10099993, Compound 125)
Affinity DataEC50:  238nMpH: 7.3 T: 2°CAssay Description:Human Embryonic Kidney (HEK-293) cell lines co-expressing rat mGlu receptors 2, 3, 4, 6, 7 or 8 and G protein-coupled inwardly-rectifying potassium (...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2019
Entry Details
US Patent

TargetMetabotropic glutamate receptor 2(Human)
Sanford-Burnham Medical Research Institute

US Patent
LigandPNGBDBM290512(US10099993, Compound 93)
Affinity DataEC50:  250nMpH: 7.3 T: 2°CAssay Description:Human Embryonic Kidney (HEK-293) cell lines co-expressing rat mGlu receptors 2, 3, 4, 6, 7 or 8 and G protein-coupled inwardly-rectifying potassium (...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2019
Entry Details
US Patent

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