Compile Data Set for Download or QSAR
Report error Found 10 Enz. Inhib. hit(s) with all data for entry = 1170
TargetTryptophan 2,3-dioxygenase(Human)
Iomet Pharma

US Patent
LigandPNGBDBM50126144(CHEMBL3629569 | US10155972, Compound NewLink 1 | U...)
Affinity DataIC50: 398nMAssay Description:In two separate assays, 0.045 μg/μl of human IDO protein was pre-incubated for 10 min at RT with test compounds NewLink 1 and Incyte 1 in t...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/10/2019
Entry Details
US Patent

TargetTryptophan 2,3-dioxygenase(Human)
Iomet Pharma

US Patent
LigandPNGBDBM311863(US10155972, Compound Incyte 1)
Affinity DataIC50: 398nMAssay Description:In two separate assays, 0.045 μg/μl of human IDO protein was pre-incubated for 10 min at RT with test compounds NewLink 1 and Incyte 1 in t...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/10/2019
Entry Details
US Patent

TargetTryptophan 2,3-dioxygenase(Human)
Iomet Pharma

US Patent
LigandPNGBDBM50126144(CHEMBL3629569 | US10155972, Compound NewLink 1 | U...)
Affinity DataIC50: 501nMAssay Description:In two separate assays, 2.5 μg/μl of human TDO protein was pre-incubated for 10 minutes at RT with test compounds 680C91 and LM10 in the pr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/10/2019
Entry Details
US Patent

TargetTryptophan 2,3-dioxygenase(Human)
Iomet Pharma

US Patent
LigandPNGBDBM311863(US10155972, Compound Incyte 1)
Affinity DataIC50: 2.51E+3nMAssay Description:In two separate assays, 2.5 μg/μl of human TDO protein was pre-incubated for 10 minutes at RT with test compounds 680C91 and LM10 in the pr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/10/2019
Entry Details
US Patent

TargetTryptophan 2,3-dioxygenase(Human)
Iomet Pharma

US Patent
LigandPNGBDBM311866(US10155972, IOmet compound B)
Affinity DataIC50: 3.98E+3nMAssay Description:In two separate assays, 2.5 μg/μl of human TDO protein was pre-incubated for 10 minutes at RT with test compounds 680C91 and LM10 in the pr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/10/2019
Entry Details
US Patent

TargetTryptophan 2,3-dioxygenase(Human)
Iomet Pharma

US Patent
LigandPNGBDBM311865(US10155972, IOmet compound A)
Affinity DataIC50: 6.31E+3nMAssay Description:In two separate assays, 2.5 μg/μl of human TDO protein was pre-incubated for 10 minutes at RT with test compounds 680C91 and LM10 in the pr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/10/2019
Entry Details
US Patent

TargetTryptophan 2,3-dioxygenase(Human)
Iomet Pharma

US Patent
LigandPNGBDBM311862(US10155972, Compound LM10)
Affinity DataIC50: 7.94E+3nMAssay Description:In two separate assays, 2.5 μg/μl of human TDO protein was pre-incubated for 10 minutes at RT with test compounds 680C91 and LM10 in the pr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/10/2019
Entry Details
US Patent
PDB3D3D Structure (crystal)
TargetTryptophan 2,3-dioxygenase(Human)
Iomet Pharma

US Patent
LigandPNGBDBM50289137(6-Fluoro-3-((E)-2-pyridin-3-yl-vinyl)-1H-indole | ...)
Affinity DataIC50: 1.00E+4nMAssay Description:In two separate assays, 2.5 μg/μl of human TDO protein was pre-incubated for 10 minutes at RT with test compounds 680C91 and LM10 in the pr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/10/2019
Entry Details
US Patent

TargetTryptophan 2,3-dioxygenase(Human)
Iomet Pharma

US Patent
LigandPNGBDBM311865(US10155972, IOmet compound A)
Affinity DataIC50: 1.26E+5nMAssay Description:In two separate assays, 0.045 μg/μl of human IDO protein was pre-incubated for 10 min at RT with test compounds NewLink 1 and Incyte 1 in t...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/10/2019
Entry Details
US Patent

TargetTryptophan 2,3-dioxygenase(Human)
Iomet Pharma

US Patent
LigandPNGBDBM311866(US10155972, IOmet compound B)
Affinity DataIC50: 1.26E+5nMAssay Description:In two separate assays, 0.045 μg/μl of human IDO protein was pre-incubated for 10 min at RT with test compounds NewLink 1 and Incyte 1 in t...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/10/2019
Entry Details
US Patent