Compile Data Set for Download or QSAR
Report error Found 117 Enz. Inhib. hit(s) with all data for entry = 1468
TargetProtein M2-1(Human respiratory syncytial virus A (strain A2))
Hoffmann-La Roche

US Patent
LigandPNGBDBM324744(1'-({5-Chloro-1-[2-(1,1- dioxidothietan-3-yl)ethyl...)
Affinity DataEC50:  1.10nMAssay Description:To measure anti-RSV activity of compounds, 96-well plates are seeded with 6×103 cells per well in Dulbecco's modified Eagle's medium (DMEM) c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/26/2019
Entry Details
US Patent

TargetProtein M2-1(Human respiratory syncytial virus A (strain A2))
Hoffmann-La Roche

US Patent
LigandPNGBDBM324745(1'-({5-Chloro-1-[3- (methylsulfonyl)propyl]-1H- be...)
Affinity DataEC50:  2nMAssay Description:To measure anti-RSV activity of compounds, 96-well plates are seeded with 6×103 cells per well in Dulbecco's modified Eagle's medium (DMEM) c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/26/2019
Entry Details
US Patent

TargetProtein M2-1(Human respiratory syncytial virus A (strain A2))
Hoffmann-La Roche

US Patent
LigandPNGBDBM324714(1'-({5-Chloro-1-[3- (ethylsulfonyl)propyl]-1H-indo...)
Affinity DataEC50:  3nMAssay Description:To measure anti-RSV activity of compounds, 96-well plates are seeded with 6×103 cells per well in Dulbecco's modified Eagle's medium (DMEM) c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/26/2019
Entry Details
US Patent

TargetProtein M2-1(Human respiratory syncytial virus A (strain A2))
Hoffmann-La Roche

US Patent
LigandPNGBDBM324749(1'-{[5-Chloro-1-(oxetan-3-ylmethyl)- 1H-benzimidaz...)
Affinity DataEC50:  3nMAssay Description:To measure anti-RSV activity of compounds, 96-well plates are seeded with 6×103 cells per well in Dulbecco's modified Eagle's medium (DMEM) c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/26/2019
Entry Details
US Patent

TargetProtein M2-1(Human respiratory syncytial virus A (strain A2))
Hoffmann-La Roche

US Patent
LigandPNGBDBM324694(US10189838, Example 10 | 1''-[{5-Chloro-1-[3- (met...)
Affinity DataEC50:  3nMAssay Description:To measure anti-RSV activity of compounds, 96-well plates are seeded with 6×103 cells per well in Dulbecco's modified Eagle's medium (DMEM) c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/26/2019
Entry Details
US Patent

TargetProtein M2-1(Human respiratory syncytial virus A (strain A2))
Hoffmann-La Roche

US Patent
LigandPNGBDBM324750(1'-({5-Chloro-1-[2-(oxetan-3- yl)ethyl]-1H-benzimi...)
Affinity DataEC50:  3nMAssay Description:To measure anti-RSV activity of compounds, 96-well plates are seeded with 6×103 cells per well in Dulbecco's modified Eagle's medium (DMEM) c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/26/2019
Entry Details
US Patent

TargetProtein M2-1(Human respiratory syncytial virus A (strain A2))
Hoffmann-La Roche

US Patent
LigandPNGBDBM324648(1'-({5-Chloro-7-fluoro-1-[2- (methylsulfonyl)ethyl...)
Affinity DataEC50:  3.40nMAssay Description:To measure anti-RSV activity of compounds, 96-well plates are seeded with 6×103 cells per well in Dulbecco's modified Eagle's medium (DMEM) c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/26/2019
Entry Details
US Patent

TargetProtein M2-1(Human respiratory syncytial virus A (strain A2))
Hoffmann-La Roche

US Patent
LigandPNGBDBM324737(1'-({6-Chloro-3-[2- (methylsulfonyl)ethyl]-1H-indo...)
Affinity DataEC50:  5nMAssay Description:To measure anti-RSV activity of compounds, 96-well plates are seeded with 6×103 cells per well in Dulbecco's modified Eagle's medium (DMEM) c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/26/2019
Entry Details
US Patent

TargetProtein M2-1(Human respiratory syncytial virus A (strain A2))
Hoffmann-La Roche

US Patent
LigandPNGBDBM324663(1'-({5-Chloro-1-[4- (methylsulfonyl)butyl]-1H-indo...)
Affinity DataEC50:  5.90nMAssay Description:To measure anti-RSV activity of compounds, 96-well plates are seeded with 6×103 cells per well in Dulbecco's modified Eagle's medium (DMEM) c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/26/2019
Entry Details
US Patent

TargetProtein M2-1(Human respiratory syncytial virus A (strain A2))
Hoffmann-La Roche

US Patent
LigandPNGBDBM324729(1'-[(5-Chloro-1-{2-[4- (methylsulfonyl)piperazin-1...)
Affinity DataEC50:  6nMAssay Description:To measure anti-RSV activity of compounds, 96-well plates are seeded with 6×103 cells per well in Dulbecco's modified Eagle's medium (DMEM) c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/26/2019
Entry Details
US Patent

TargetProtein M2-1(Human respiratory syncytial virus A (strain A2))
Hoffmann-La Roche

US Patent
LigandPNGBDBM324698(1'-({5-Chloro-1-[3-(S- methylsulfomidoyl)propyl]-1...)
Affinity DataEC50:  6nMAssay Description:To measure anti-RSV activity of compounds, 96-well plates are seeded with 6×103 cells per well in Dulbecco's modified Eagle's medium (DMEM) c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/26/2019
Entry Details
US Patent

TargetProtein M2-1(Human respiratory syncytial virus A (strain A2))
Hoffmann-La Roche

US Patent
LigandPNGBDBM324738(1'-({6-Chloro-3-[3- (methylsulfonyl)propyl]-1H-ind...)
Affinity DataEC50:  6nMAssay Description:To measure anti-RSV activity of compounds, 96-well plates are seeded with 6×103 cells per well in Dulbecco's modified Eagle's medium (DMEM) c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/26/2019
Entry Details
US Patent

TargetProtein M2-1(Human respiratory syncytial virus A (strain A2))
Hoffmann-La Roche

US Patent
LigandPNGBDBM324699(1'-({5-Chloro-1-[2-(S- methylsulfonimidoyl)ethyl]-...)
Affinity DataEC50:  7nMAssay Description:To measure anti-RSV activity of compounds, 96-well plates are seeded with 6×103 cells per well in Dulbecco's modified Eagle's medium (DMEM) c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/26/2019
Entry Details
US Patent

TargetProtein M2-1(Human respiratory syncytial virus A (strain A2))
Hoffmann-La Roche

US Patent
LigandPNGBDBM324682(3-{5-Chloro-2-[(2'- oxospiro[cyclopropane-1,3'- py...)
Affinity DataEC50:  7nMAssay Description:To measure anti-RSV activity of compounds, 96-well plates are seeded with 6×103 cells per well in Dulbecco's modified Eagle's medium (DMEM) c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/26/2019
Entry Details
US Patent

TargetProtein M2-1(Human respiratory syncytial virus A (strain A2))
Hoffmann-La Roche

US Patent
LigandPNGBDBM324687(1'-[(5-Chloro-1-{3-[(3-oxopiperazin- 1-yl)sulfonyl...)
Affinity DataEC50:  7nMAssay Description:To measure anti-RSV activity of compounds, 96-well plates are seeded with 6×103 cells per well in Dulbecco's modified Eagle's medium (DMEM) c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/26/2019
Entry Details
US Patent

TargetProtein M2-1(Human respiratory syncytial virus A (strain A2))
Hoffmann-La Roche

US Patent
LigandPNGBDBM324651(1'-({5-Chloro-1-[2- (ethylsulfonyl)ethyl]-1H-indol...)
Affinity DataEC50:  7.67nMAssay Description:To measure anti-RSV activity of compounds, 96-well plates are seeded with 6×103 cells per well in Dulbecco's modified Eagle's medium (DMEM) c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/26/2019
Entry Details
US Patent

TargetProtein M2-1(Human respiratory syncytial virus A (strain A2))
Hoffmann-La Roche

US Patent
LigandPNGBDBM324746(1'-({5-Chloro-1-[2- (cyclopropylsulfonyl)ethyl]-1H...)
Affinity DataEC50:  8nMAssay Description:To measure anti-RSV activity of compounds, 96-well plates are seeded with 6×103 cells per well in Dulbecco's modified Eagle's medium (DMEM) c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/26/2019
Entry Details
US Patent

TargetProtein M2-1(Human respiratory syncytial virus A (strain A2))
Hoffmann-La Roche

US Patent
LigandPNGBDBM324649(1'-({5-Methyl-1-[2- (methylsulfonyl)ethyl]-1H-indo...)
Affinity DataEC50:  9nMAssay Description:To measure anti-RSV activity of compounds, 96-well plates are seeded with 6×103 cells per well in Dulbecco's modified Eagle's medium (DMEM) c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/26/2019
Entry Details
US Patent

TargetProtein M2-1(Human respiratory syncytial virus A (strain A2))
Hoffmann-La Roche

US Patent
LigandPNGBDBM324747(1'-({5-Chloro-7-fluoro-1-[2- (methylsulfonyl)ethyl...)
Affinity DataEC50:  9nMAssay Description:To measure anti-RSV activity of compounds, 96-well plates are seeded with 6×103 cells per well in Dulbecco's modified Eagle's medium (DMEM) c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/26/2019
Entry Details
US Patent

TargetProtein M2-1(Human respiratory syncytial virus A (strain A2))
Hoffmann-La Roche

US Patent
LigandPNGBDBM324736(1'-({6-Chloro-3-[2- (ethylsulfonyl)ethyl]-1H-indol...)
Affinity DataEC50:  9nMAssay Description:To measure anti-RSV activity of compounds, 96-well plates are seeded with 6×103 cells per well in Dulbecco's modified Eagle's medium (DMEM) c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/26/2019
Entry Details
US Patent

TargetProtein M2-1(Human respiratory syncytial virus A (strain A2))
Hoffmann-La Roche

US Patent
LigandPNGBDBM324679(1'-({5-Chloro-1-[3- (methylsulfinyl)propyl]-1H-ind...)
Affinity DataEC50:  9nMAssay Description:To measure anti-RSV activity of compounds, 96-well plates are seeded with 6×103 cells per well in Dulbecco's modified Eagle's medium (DMEM) c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/26/2019
Entry Details
US Patent

TargetProtein M2-1(Human respiratory syncytial virus A (strain A2))
Hoffmann-La Roche

US Patent
LigandPNGBDBM324708(4-{5-Chloro-2-[(2'- oxospiro[cyclopropane-1,3'- py...)
Affinity DataEC50:  11nMAssay Description:To measure anti-RSV activity of compounds, 96-well plates are seeded with 6×103 cells per well in Dulbecco's modified Eagle's medium (DMEM) c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/26/2019
Entry Details
US Patent

TargetProtein M2-1(Human respiratory syncytial virus A (strain A2))
Hoffmann-La Roche

US Patent
LigandPNGBDBM324724(3-{5-Chloro-2-[(2'- oxospiro[cyclopropane-1,3'- py...)
Affinity DataEC50:  11nMAssay Description:To measure anti-RSV activity of compounds, 96-well plates are seeded with 6×103 cells per well in Dulbecco's modified Eagle's medium (DMEM) c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/26/2019
Entry Details
US Patent

TargetProtein M2-1(Human respiratory syncytial virus A (strain A2))
Hoffmann-La Roche

US Patent
LigandPNGBDBM324730(N-(2-{5-Chloro-2-[(2'- oxospiro[cyclopropane-1,3'-...)
Affinity DataEC50:  11.5nMAssay Description:To measure anti-RSV activity of compounds, 96-well plates are seeded with 6×103 cells per well in Dulbecco's modified Eagle's medium (DMEM) c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/26/2019
Entry Details
US Patent

TargetProtein M2-1(Human respiratory syncytial virus A (strain A2))
Hoffmann-La Roche

US Patent
LigandPNGBDBM324739(1'-({5-Chloro-1-[2- (methylsulfonyl)ethyl]-1H- ben...)
Affinity DataEC50:  12nMAssay Description:To measure anti-RSV activity of compounds, 96-well plates are seeded with 6×103 cells per well in Dulbecco's modified Eagle's medium (DMEM) c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/26/2019
Entry Details
US Patent

TargetProtein M2-1(Human respiratory syncytial virus A (strain A2))
Hoffmann-La Roche

US Patent
LigandPNGBDBM324743(1'-({5-Chloro-1-[2- (ethylsulfonyl)ethyl]-1H- benz...)
Affinity DataEC50:  13nMAssay Description:To measure anti-RSV activity of compounds, 96-well plates are seeded with 6×103 cells per well in Dulbecco's modified Eagle's medium (DMEM) c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/26/2019
Entry Details
US Patent

TargetProtein M2-1(Human respiratory syncytial virus A (strain A2))
Hoffmann-La Roche

US Patent
LigandPNGBDBM324685(1'-({5-Chloro-1-[3-(morpholin-4- ylsulfonyl)propyl...)
Affinity DataEC50:  14nMAssay Description:To measure anti-RSV activity of compounds, 96-well plates are seeded with 6×103 cells per well in Dulbecco's modified Eagle's medium (DMEM) c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/26/2019
Entry Details
US Patent

TargetProtein M2-1(Human respiratory syncytial virus A (strain A2))
Hoffmann-La Roche

US Patent
LigandPNGBDBM324641(1'-({5-Bromo-1-[2- (methylsulfonyl)ethyl]-1H-indol...)
Affinity DataEC50:  14nMAssay Description:To measure anti-RSV activity of compounds, 96-well plates are seeded with 6×103 cells per well in Dulbecco's modified Eagle's medium (DMEM) c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/26/2019
Entry Details
US Patent

TargetProtein M2-1(Human respiratory syncytial virus A (strain A2))
Hoffmann-La Roche

US Patent
LigandPNGBDBM324719(1'-({5-Chloro-1-[3-(piperazin-1- ylsulfonyl)propyl...)
Affinity DataEC50:  15nMAssay Description:To measure anti-RSV activity of compounds, 96-well plates are seeded with 6×103 cells per well in Dulbecco's modified Eagle's medium (DMEM) c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/26/2019
Entry Details
US Patent

TargetProtein M2-1(Human respiratory syncytial virus A (strain A2))
Hoffmann-La Roche

US Patent
LigandPNGBDBM324748(1'-({5,7-Dichloro-1-[2- (methylsulfonyl)ethyl]-1H-...)
Affinity DataEC50:  16.8nMAssay Description:To measure anti-RSV activity of compounds, 96-well plates are seeded with 6×103 cells per well in Dulbecco's modified Eagle's medium (DMEM) c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/26/2019
Entry Details
US Patent

TargetProtein M2-1(Human respiratory syncytial virus A (strain A2))
Hoffmann-La Roche

US Patent
LigandPNGBDBM324706(3-{5-Chloro-2-[(2'- oxospiro[cyclopropane-1,3'- py...)
Affinity DataEC50:  17nMAssay Description:To measure anti-RSV activity of compounds, 96-well plates are seeded with 6×103 cells per well in Dulbecco's modified Eagle's medium (DMEM) c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/26/2019
Entry Details
US Patent

TargetProtein M2-1(Human respiratory syncytial virus A (strain A2))
Hoffmann-La Roche

US Patent
LigandPNGBDBM324697(Ethyl 3-{5-chloro-7-fluoro-2-[(2'- oxospiro[cyclop...)
Affinity DataEC50:  18nMAssay Description:To measure anti-RSV activity of compounds, 96-well plates are seeded with 6×103 cells per well in Dulbecco's modified Eagle's medium (DMEM) c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/26/2019
Entry Details
US Patent

TargetProtein M2-1(Human respiratory syncytial virus A (strain A2))
Hoffmann-La Roche

US Patent
LigandPNGBDBM324673(1'-({5-Chloro-1-[2-(1,1- dioxidothietan-3-yl)ethyl...)
Affinity DataEC50:  18nMAssay Description:To measure anti-RSV activity of compounds, 96-well plates are seeded with 6×103 cells per well in Dulbecco's modified Eagle's medium (DMEM) c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/26/2019
Entry Details
US Patent

TargetProtein M2-1(Human respiratory syncytial virus A (strain A2))
Hoffmann-La Roche

US Patent
LigandPNGBDBM324689(1'-({5-Chloro-1-[4-(1,1-dioxido-1,2- thiazolidin-2...)
Affinity DataEC50:  18nMAssay Description:To measure anti-RSV activity of compounds, 96-well plates are seeded with 6×103 cells per well in Dulbecco's modified Eagle's medium (DMEM) c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/26/2019
Entry Details
US Patent

TargetProtein M2-1(Human respiratory syncytial virus A (strain A2))
Hoffmann-La Roche

US Patent
LigandPNGBDBM324752(1'-({1-[(3-Aminooxetan-3- yl)methyl]-5-chloro-1H- ...)
Affinity DataEC50:  18nMAssay Description:To measure anti-RSV activity of compounds, 96-well plates are seeded with 6×103 cells per well in Dulbecco's modified Eagle's medium (DMEM) c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/26/2019
Entry Details
US Patent

TargetProtein M2-1(Human respiratory syncytial virus A (strain A2))
Hoffmann-La Roche

US Patent
LigandPNGBDBM324677(1'-({5-Chloro-1-[3- (methylsulfonyl)propyl]-1H- py...)
Affinity DataEC50:  18nMAssay Description:To measure anti-RSV activity of compounds, 96-well plates are seeded with 6×103 cells per well in Dulbecco's modified Eagle's medium (DMEM) c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/26/2019
Entry Details
US Patent

TargetProtein M2-1(Human respiratory syncytial virus A (strain A2))
Hoffmann-La Roche

US Patent
LigandPNGBDBM324662(US10189838, Example 3-3 | 1''-({5-Chloro-1-[2- (me...)
Affinity DataEC50:  18nMAssay Description:To measure anti-RSV activity of compounds, 96-well plates are seeded with 6×103 cells per well in Dulbecco's modified Eagle's medium (DMEM) c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/26/2019
Entry Details
US Patent

TargetProtein M2-1(Human respiratory syncytial virus A (strain A2))
Hoffmann-La Roche

US Patent
LigandPNGBDBM324705(Methyl 4-{5-chloro-2-[(2'- oxospiro[cyclopropane-1...)
Affinity DataEC50:  18.6nMAssay Description:To measure anti-RSV activity of compounds, 96-well plates are seeded with 6×103 cells per well in Dulbecco's modified Eagle's medium (DMEM) c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/26/2019
Entry Details
US Patent

TargetProtein M2-1(Human respiratory syncytial virus A (strain A2))
Hoffmann-La Roche

US Patent
LigandPNGBDBM324652(1'-({5-Chloro-1-[2- (ethylsulfonyl)ethyl]-1H-pyrro...)
Affinity DataEC50:  19nMAssay Description:To measure anti-RSV activity of compounds, 96-well plates are seeded with 6×103 cells per well in Dulbecco's modified Eagle's medium (DMEM) c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/26/2019
Entry Details
US Patent

TargetProtein M2-1(Human respiratory syncytial virus A (strain A2))
Hoffmann-La Roche

US Patent
LigandPNGBDBM324720(1'-[(5-Chloro-1-{3-[(1R,4R)-2,5- diazabicyclo[2.2....)
Affinity DataEC50:  19nMAssay Description:To measure anti-RSV activity of compounds, 96-well plates are seeded with 6×103 cells per well in Dulbecco's modified Eagle's medium (DMEM) c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/26/2019
Entry Details
US Patent

TargetProtein M2-1(Human respiratory syncytial virus A (strain A2))
Hoffmann-La Roche

US Patent
LigandPNGBDBM324662(US10189838, Example 3-3 | 1''-({5-Chloro-1-[2- (me...)
Affinity DataEC50:  19nMAssay Description:To measure anti-RSV activity of compounds, 96-well plates are seeded with 6×103 cells per well in Dulbecco's modified Eagle's medium (DMEM) c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/26/2019
Entry Details
US Patent

TargetProtein M2-1(Human respiratory syncytial virus A (strain A2))
Hoffmann-La Roche

US Patent
LigandPNGBDBM324695(Ethyl 3-{5-chloro-2-[(2'- oxospiro[cyclopropane-1,...)
Affinity DataEC50:  19nMAssay Description:To measure anti-RSV activity of compounds, 96-well plates are seeded with 6×103 cells per well in Dulbecco's modified Eagle's medium (DMEM) c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/26/2019
Entry Details
US Patent

TargetProtein M2-1(Human respiratory syncytial virus A (strain A2))
Hoffmann-La Roche

US Patent
LigandPNGBDBM324694(US10189838, Example 10 | 1''-[{5-Chloro-1-[3- (met...)
Affinity DataEC50:  19nMAssay Description:To measure anti-RSV activity of compounds, 96-well plates are seeded with 6×103 cells per well in Dulbecco's modified Eagle's medium (DMEM) c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/26/2019
Entry Details
US Patent

TargetProtein M2-1(Human respiratory syncytial virus A (strain A2))
Hoffmann-La Roche

US Patent
LigandPNGBDBM324686(1'-({5-Chloro-1-[3-(pyrrolidin-1- ylsulfonyl)propy...)
Affinity DataEC50:  20nMAssay Description:To measure anti-RSV activity of compounds, 96-well plates are seeded with 6×103 cells per well in Dulbecco's modified Eagle's medium (DMEM) c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/26/2019
Entry Details
US Patent

TargetProtein M2-1(Human respiratory syncytial virus A (strain A2))
Hoffmann-La Roche

US Patent
LigandPNGBDBM324734(Methyl (3-{5-chloro-2-[(2'- oxospiro[cyclopropane-...)
Affinity DataEC50:  20nMAssay Description:To measure anti-RSV activity of compounds, 96-well plates are seeded with 6×103 cells per well in Dulbecco's modified Eagle's medium (DMEM) c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/26/2019
Entry Details
US Patent

TargetProtein M2-1(Human respiratory syncytial virus A (strain A2))
Hoffmann-La Roche

US Patent
LigandPNGBDBM324740(1'-({5-Chloro-1-[2- (methylsulfonyl)ethyl]-1H- ben...)
Affinity DataEC50:  20nMAssay Description:To measure anti-RSV activity of compounds, 96-well plates are seeded with 6×103 cells per well in Dulbecco's modified Eagle's medium (DMEM) c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/26/2019
Entry Details
US Patent

TargetProtein M2-1(Human respiratory syncytial virus A (strain A2))
Hoffmann-La Roche

US Patent
LigandPNGBDBM324667(1'-({5-Chloro-1-[4- (methylsulfonyl)butyl]-1H- pyr...)
Affinity DataEC50:  22.1nMAssay Description:To measure anti-RSV activity of compounds, 96-well plates are seeded with 6×103 cells per well in Dulbecco's modified Eagle's medium (DMEM) c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/26/2019
Entry Details
US Patent

TargetProtein M2-1(Human respiratory syncytial virus A (strain A2))
Hoffmann-La Roche

US Patent
LigandPNGBDBM324684(2-{5-Chloro-2-[(2'- oxospiro[cyclopropane-1,3'- py...)
Affinity DataEC50:  23nMAssay Description:To measure anti-RSV activity of compounds, 96-well plates are seeded with 6×103 cells per well in Dulbecco's modified Eagle's medium (DMEM) c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/26/2019
Entry Details
US Patent

TargetProtein M2-1(Human respiratory syncytial virus A (strain A2))
Hoffmann-La Roche

US Patent
LigandPNGBDBM324645(1'-({5,7-Difluoro-1-[2- (methylsulfonyl)ethyl]-1H-...)
Affinity DataEC50:  24nMAssay Description:To measure anti-RSV activity of compounds, 96-well plates are seeded with 6×103 cells per well in Dulbecco's modified Eagle's medium (DMEM) c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/26/2019
Entry Details
US Patent

TargetProtein M2-1(Human respiratory syncytial virus A (strain A2))
Hoffmann-La Roche

US Patent
LigandPNGBDBM324728(N-(2-{5-Chloro-2-[(2'- oxospiro[cyclopropane-1,3'-...)
Affinity DataEC50:  25nMAssay Description:To measure anti-RSV activity of compounds, 96-well plates are seeded with 6×103 cells per well in Dulbecco's modified Eagle's medium (DMEM) c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/26/2019
Entry Details
US Patent

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