Compile Data Set for Download or QSAR
Report error Found 633 Enz. Inhib. hit(s) with all data for entry = 1833
TargetTyrosine-protein kinase JAK1 [850-1154](Human)
Galapagos

US Patent
LigandChemical structure of BindingDB Monomer ID 348932BDBM348932(N-(5-(4-phenoxyphenyl)- [1,2,4]triazolo[1,5-a]pyri...)
Affinity DataIC50: 100nMAssay Description:Recombinant human JAK1 catalytic domain (amino acids 850-1154; catalog number 08-144) was purchased from Carna Biosciences. 10 ng of JAK1 was incubat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/21/2019
Entry Details
US Patent

TargetTyrosine-protein kinase JAK3 [781-1124](Human)
Galapagos

US Patent
LigandChemical structure of BindingDB Monomer ID 348970BDBM348970(4-(2- (cyclopropanecarboxamido)- [1,2,4]triazolo[1...)
Affinity DataIC50: 100nMAssay Description:Recombinant human JAK3 catalytic domain (amino acids 781-1124; catalog number PV3855) was purchased from Invitrogen. 0.025 mU of JAK3 was incubated w...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/21/2019
Entry Details
US Patent

TargetTyrosine-protein kinase JAK3 [781-1124](Human)
Galapagos

US Patent
LigandChemical structure of BindingDB Monomer ID 348964BDBM348964(N-(5-(4-((6- (trifluoromethyl)pyridin-3- yl)methox...)
Affinity DataIC50: 100nMAssay Description:Recombinant human JAK3 catalytic domain (amino acids 781-1124; catalog number PV3855) was purchased from Invitrogen. 0.025 mU of JAK3 was incubated w...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/21/2019
Entry Details
US Patent

TargetTyrosine-protein kinase JAK1 [850-1154](Human)
Galapagos

US Patent
LigandChemical structure of BindingDB Monomer ID 348936BDBM348936(N-(5-(4-((1,3-dimethyl-1H- pyrazol-5-yl)methyldime...)
Affinity DataIC50: 100nMAssay Description:Recombinant human JAK1 catalytic domain (amino acids 850-1154; catalog number 08-144) was purchased from Carna Biosciences. 10 ng of JAK1 was incubat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/21/2019
Entry Details
US Patent

TargetTyrosine-protein kinase JAK1 [850-1154](Human)
Galapagos

US Patent
LigandChemical structure of BindingDB Monomer ID 348937BDBM348937(N-(5-(4-(2-(3,5-dimethyl-1H- pyrazol-4-yl)ethyldim...)
Affinity DataIC50: 100nMAssay Description:Recombinant human JAK1 catalytic domain (amino acids 850-1154; catalog number 08-144) was purchased from Carna Biosciences. 10 ng of JAK1 was incubat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/21/2019
Entry Details
US Patent

TargetTyrosine-protein kinase JAK1 [850-1154](Human)
Galapagos

US Patent
LigandChemical structure of BindingDB Monomer ID 348934BDBM348934(N-(5-(4-((1-methyl-1H- pyrazol-3-yl)methylmethyl- ...)
Affinity DataIC50: 100nMAssay Description:Recombinant human JAK1 catalytic domain (amino acids 850-1154; catalog number 08-144) was purchased from Carna Biosciences. 10 ng of JAK1 was incubat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/21/2019
Entry Details
US Patent

TargetTyrosine-protein kinase JAK1 [850-1154](Human)
Galapagos

US Patent
LigandChemical structure of BindingDB Monomer ID 348935BDBM348935(N-(5-(4-((3,5- dimethylisoxazol-4- yl)methoxy)phen...)
Affinity DataIC50: 100nMAssay Description:Recombinant human JAK1 catalytic domain (amino acids 850-1154; catalog number 08-144) was purchased from Carna Biosciences. 10 ng of JAK1 was incubat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/21/2019
Entry Details
US Patent

TargetTyrosine-protein kinase JAK1 [850-1154](Human)
Galapagos

US Patent
LigandChemical structure of BindingDB Monomer ID 348925BDBM348925(N-(5-(4- (cyclobutylmethoxy)phenyl)- [1,2,4]triazo...)
Affinity DataIC50: 100nMAssay Description:Recombinant human JAK1 catalytic domain (amino acids 850-1154; catalog number 08-144) was purchased from Carna Biosciences. 10 ng of JAK1 was incubat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/21/2019
Entry Details
US Patent

TargetTyrosine-protein kinase JAK3 [781-1124](Human)
Galapagos

US Patent
LigandChemical structure of BindingDB Monomer ID 348946BDBM348946(4-(2- (cyclopropanecarboxamido)- [1,2,4]triazolo[1...)
Affinity DataIC50: 100nMAssay Description:Recombinant human JAK3 catalytic domain (amino acids 781-1124; catalog number PV3855) was purchased from Invitrogen. 0.025 mU of JAK3 was incubated w...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/21/2019
Entry Details
US Patent

TargetTyrosine-protein kinase JAK1 [850-1154](Human)
Galapagos

US Patent
LigandChemical structure of BindingDB Monomer ID 348922BDBM348922(N-(5-(4-(pyridin-3- ylmethoxy)phenyl)- [1,2,4]tria...)
Affinity DataIC50: 100nMAssay Description:Recombinant human JAK1 catalytic domain (amino acids 850-1154; catalog number 08-144) was purchased from Carna Biosciences. 10 ng of JAK1 was incubat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/21/2019
Entry Details
US Patent

TargetTyrosine-protein kinase JAK3 [781-1124](Human)
Galapagos

US Patent
LigandChemical structure of BindingDB Monomer ID 348948BDBM348948(N-(5-(4-((1,5-dimethyl-1H- pyrazol-3-yl)methyldime...)
Affinity DataIC50: 100nMAssay Description:Recombinant human JAK3 catalytic domain (amino acids 781-1124; catalog number PV3855) was purchased from Invitrogen. 0.025 mU of JAK3 was incubated w...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/21/2019
Entry Details
US Patent

TargetTyrosine-protein kinase JAK1 [850-1154](Human)
Galapagos

US Patent
LigandChemical structure of BindingDB Monomer ID 348923BDBM348923(N-(5-(4-(pyridin-2- ylmethoxy)phenyl)- [1,2,4]tria...)
Affinity DataIC50: 100nMAssay Description:Recombinant human JAK1 catalytic domain (amino acids 850-1154; catalog number 08-144) was purchased from Carna Biosciences. 10 ng of JAK1 was incubat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/21/2019
Entry Details
US Patent

TargetTyrosine-protein kinase JAK3 [781-1124](Human)
Galapagos

US Patent
LigandChemical structure of BindingDB Monomer ID 348962BDBM348962(N-(5-(4-(2- phenylethylsulfonamido) phenyl)-[1,2,4...)
Affinity DataIC50: 100nMAssay Description:Recombinant human JAK3 catalytic domain (amino acids 781-1124; catalog number PV3855) was purchased from Invitrogen. 0.025 mU of JAK3 was incubated w...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/21/2019
Entry Details
US Patent

TargetTyrosine-protein kinase JAK1 [850-1154](Human)
Galapagos

US Patent
LigandChemical structure of BindingDB Monomer ID 348926BDBM348926(N-(5-(4- (cyclopentyloxy)phenyl)- [1,2,4]triazolo[...)
Affinity DataIC50: 100nMAssay Description:Recombinant human JAK1 catalytic domain (amino acids 850-1154; catalog number 08-144) was purchased from Carna Biosciences. 10 ng of JAK1 was incubat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/21/2019
Entry Details
US Patent

TargetTyrosine-protein kinase JAK1 [850-1154](Human)
Galapagos

US Patent
LigandChemical structure of BindingDB Monomer ID 348927BDBM348927(N-(5-(4- (cyclohexylmethoxy)phenyl)- [1,2,4]triazo...)
Affinity DataIC50: 100nMAssay Description:Recombinant human JAK1 catalytic domain (amino acids 850-1154; catalog number 08-144) was purchased from Carna Biosciences. 10 ng of JAK1 was incubat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/21/2019
Entry Details
US Patent

TargetTyrosine-protein kinase JAK1 [850-1154](Human)
Galapagos

US Patent
LigandChemical structure of BindingDB Monomer ID 348948BDBM348948(N-(5-(4-((1,5-dimethyl-1H- pyrazol-3-yl)methyldime...)
Affinity DataIC50: 100nMAssay Description:Recombinant human JAK1 catalytic domain (amino acids 850-1154; catalog number 08-144) was purchased from Carna Biosciences. 10 ng of JAK1 was incubat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/21/2019
Entry Details
US Patent

TargetTyrosine-protein kinase JAK1 [850-1154](Human)
Galapagos

US Patent
LigandChemical structure of BindingDB Monomer ID 348946BDBM348946(4-(2- (cyclopropanecarboxamido)- [1,2,4]triazolo[1...)
Affinity DataIC50: 100nMAssay Description:Recombinant human JAK1 catalytic domain (amino acids 850-1154; catalog number 08-144) was purchased from Carna Biosciences. 10 ng of JAK1 was incubat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/21/2019
Entry Details
US Patent

TargetTyrosine-protein kinase JAK3 [781-1124](Human)
Galapagos

US Patent
LigandChemical structure of BindingDB Monomer ID 349038BDBM349038(N-(5-(4-(4-benzyl-4- hydroxypiperidine-1- carbonyl...)
Affinity DataIC50: 100nMAssay Description:Recombinant human JAK3 catalytic domain (amino acids 781-1124; catalog number PV3855) was purchased from Invitrogen. 0.025 mU of JAK3 was incubated w...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/21/2019
Entry Details
US Patent

TargetTyrosine-protein kinase JAK1 [850-1154](Human)
Galapagos

US Patent
LigandChemical structure of BindingDB Monomer ID 348952BDBM348952(N-(5-(4-(pyridin-3-yl)phenyl)- [1,2,4]triazolo[1,5...)
Affinity DataIC50: 100nMAssay Description:Recombinant human JAK1 catalytic domain (amino acids 850-1154; catalog number 08-144) was purchased from Carna Biosciences. 10 ng of JAK1 was incubat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/21/2019
Entry Details
US Patent

TargetTyrosine-protein kinase JAK3 [781-1124](Human)
Galapagos

US Patent
LigandChemical structure of BindingDB Monomer ID 348899BDBM348899(US10206907, Compound 163 | N-(5-(4-(benzyloxy)phen...)
Affinity DataIC50: 100nMAssay Description:Recombinant human JAK3 catalytic domain (amino acids 781-1124; catalog number PV3855) was purchased from Invitrogen. 0.025 mU of JAK3 was incubated w...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/21/2019
Entry Details
US Patent

TargetTyrosine-protein kinase JAK1 [850-1154](Human)
Galapagos

US Patent
LigandChemical structure of BindingDB Monomer ID 348950BDBM348950(N-(5-(4-(pyridine-3- sulfonamido)phenyl)- [1,2,4]t...)
Affinity DataIC50: 100nMAssay Description:Recombinant human JAK1 catalytic domain (amino acids 850-1154; catalog number 08-144) was purchased from Carna Biosciences. 10 ng of JAK1 was incubat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/21/2019
Entry Details
US Patent

TargetTyrosine-protein kinase JAK3 [781-1124](Human)
Galapagos

US Patent
LigandChemical structure of BindingDB Monomer ID 348981BDBM348981(N-(5-(4-((1,2,4-oxadiazol-3- yl)methoxy)phenyl)- [...)
Affinity DataIC50: 100nMAssay Description:Recombinant human JAK3 catalytic domain (amino acids 781-1124; catalog number PV3855) was purchased from Invitrogen. 0.025 mU of JAK3 was incubated w...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/21/2019
Entry Details
US Patent

TargetTyrosine-protein kinase JAK1 [850-1154](Human)
Galapagos

US Patent
LigandChemical structure of BindingDB Monomer ID 348940BDBM348940(N-(5-(4-(2- fluorophenylsulfonamido) phenyl)-[1,2,...)
Affinity DataIC50: 100nMAssay Description:Recombinant human JAK1 catalytic domain (amino acids 850-1154; catalog number 08-144) was purchased from Carna Biosciences. 10 ng of JAK1 was incubat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/21/2019
Entry Details
US Patent

TargetTyrosine-protein kinase JAK3 [781-1124](Human)
Galapagos

US Patent
LigandChemical structure of BindingDB Monomer ID 348979BDBM348979(4-(2- (cyclopropanecarboxamido)- [1,2,4]triazolo[1...)
Affinity DataIC50: 100nMAssay Description:Recombinant human JAK3 catalytic domain (amino acids 781-1124; catalog number PV3855) was purchased from Invitrogen. 0.025 mU of JAK3 was incubated w...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/21/2019
Entry Details
US Patent

TargetTyrosine-protein kinase JAK1 [850-1154](Human)
Galapagos

US Patent
LigandChemical structure of BindingDB Monomer ID 348938BDBM348938(N-(5-(4-((5-methylisoxazol-3- yl)methoxy)phenyl)- ...)
Affinity DataIC50: 100nMAssay Description:Recombinant human JAK1 catalytic domain (amino acids 850-1154; catalog number 08-144) was purchased from Carna Biosciences. 10 ng of JAK1 was incubat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/21/2019
Entry Details
US Patent

TargetTyrosine-protein kinase JAK1 [850-1154](Human)
Galapagos

US Patent
LigandChemical structure of BindingDB Monomer ID 348944BDBM348944(N-(5-(4-(1,2,3,4- tetrahydroisoquinoline-2- carbon...)
Affinity DataIC50: 100nMAssay Description:Recombinant human JAK1 catalytic domain (amino acids 850-1154; catalog number 08-144) was purchased from Carna Biosciences. 10 ng of JAK1 was incubat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/21/2019
Entry Details
US Patent

TargetTyrosine-protein kinase JAK1 [850-1154](Human)
Galapagos

US Patent
LigandChemical structure of BindingDB Monomer ID 50031742BDBM50031742(CHEMBL3360348 | US10206907, Compound 59)
Affinity DataIC50: 100nMAssay Description:Recombinant human JAK1 catalytic domain (amino acids 850-1154; catalog number 08-144) was purchased from Carna Biosciences. 10 ng of JAK1 was incubat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/21/2019
Entry Details
US Patent

TargetTyrosine-protein kinase JAK1 [850-1154](Human)
Galapagos

US Patent
LigandChemical structure of BindingDB Monomer ID 348942BDBM348942(N-benzyl-4-(2- (cyclopropanecarboxamido)- [1,2,4]t...)
Affinity DataIC50: 100nMAssay Description:Recombinant human JAK1 catalytic domain (amino acids 850-1154; catalog number 08-144) was purchased from Carna Biosciences. 10 ng of JAK1 was incubat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/21/2019
Entry Details
US Patent

TargetTyrosine-protein kinase JAK1 [850-1154](Human)
Galapagos

US Patent
LigandChemical structure of BindingDB Monomer ID 348943BDBM348943(Cyclopropanecarboxylic Acid [5-(6-benzyloxy-pyridi...)
Affinity DataIC50: 100nMAssay Description:Recombinant human JAK1 catalytic domain (amino acids 850-1154; catalog number 08-144) was purchased from Carna Biosciences. 10 ng of JAK1 was incubat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/21/2019
Entry Details
US Patent

TargetTyrosine-protein kinase JAK1 [850-1154](Human)
Galapagos

US Patent
LigandChemical structure of BindingDB Monomer ID 348964BDBM348964(N-(5-(4-((6- (trifluoromethyl)pyridin-3- yl)methox...)
Affinity DataIC50: 100nMAssay Description:Recombinant human JAK1 catalytic domain (amino acids 850-1154; catalog number 08-144) was purchased from Carna Biosciences. 10 ng of JAK1 was incubat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/21/2019
Entry Details
US Patent

TargetTyrosine-protein kinase JAK3 [781-1124](Human)
Galapagos

US Patent
LigandChemical structure of BindingDB Monomer ID 349184BDBM349184(Cyclopropanecarboxylic acid (5-{4-[2-oxo-2-(4- tri...)
Affinity DataIC50: 100nMAssay Description:Recombinant human JAK3 catalytic domain (amino acids 781-1124; catalog number PV3855) was purchased from Invitrogen. 0.025 mU of JAK3 was incubated w...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/21/2019
Entry Details
US Patent

TargetTyrosine-protein kinase JAK1 [850-1154](Human)
Galapagos

US Patent
LigandChemical structure of BindingDB Monomer ID 348965BDBM348965(N-(5-(4- (phenylsulfonamido)phenyl)- [1,2,4]triazo...)
Affinity DataIC50: 100nMAssay Description:Recombinant human JAK1 catalytic domain (amino acids 850-1154; catalog number 08-144) was purchased from Carna Biosciences. 10 ng of JAK1 was incubat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/21/2019
Entry Details
US Patent

TargetTyrosine-protein kinase JAK3 [781-1124](Human)
Galapagos

US Patent
LigandChemical structure of BindingDB Monomer ID 349167BDBM349167(Cyclopropanecarboxylic acid {5-[4-(isoxazol-3- yla...)
Affinity DataIC50: 100nMAssay Description:Recombinant human JAK3 catalytic domain (amino acids 781-1124; catalog number PV3855) was purchased from Invitrogen. 0.025 mU of JAK3 was incubated w...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/21/2019
Entry Details
US Patent

TargetTyrosine-protein kinase JAK1 [850-1154](Human)
Galapagos

US Patent
LigandChemical structure of BindingDB Monomer ID 348962BDBM348962(N-(5-(4-(2- phenylethylsulfonamido) phenyl)-[1,2,4...)
Affinity DataIC50: 100nMAssay Description:Recombinant human JAK1 catalytic domain (amino acids 850-1154; catalog number 08-144) was purchased from Carna Biosciences. 10 ng of JAK1 was incubat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/21/2019
Entry Details
US Patent

TargetTyrosine-protein kinase JAK1 [850-1154](Human)
Galapagos

US Patent
LigandChemical structure of BindingDB Monomer ID 348963BDBM348963(N-(5-(4- (phenylmethylsulfonamido) phenyl)-[1,2,4]...)
Affinity DataIC50: 100nMAssay Description:Recombinant human JAK1 catalytic domain (amino acids 850-1154; catalog number 08-144) was purchased from Carna Biosciences. 10 ng of JAK1 was incubat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/21/2019
Entry Details
US Patent

TargetTyrosine-protein kinase JAK3 [781-1124](Human)
Galapagos

US Patent
LigandChemical structure of BindingDB Monomer ID 128101BDBM128101(US8796457, 1 | US9505754, 1 | US10206907, Compound...)
Affinity DataIC50: 100nMAssay Description:Recombinant human JAK3 catalytic domain (amino acids 781-1124; catalog number PV3855) was purchased from Invitrogen. 0.025 mU of JAK3 was incubated w...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/21/2019
Entry Details
US Patent

TargetTyrosine-protein kinase JAK1 [850-1154](Human)
Galapagos

US Patent
LigandChemical structure of BindingDB Monomer ID 348968BDBM348968(N-(5-(4-(4- propylphenylsulfonamido) phenyl)-[1,2,...)
Affinity DataIC50: 100nMAssay Description:Recombinant human JAK1 catalytic domain (amino acids 850-1154; catalog number 08-144) was purchased from Carna Biosciences. 10 ng of JAK1 was incubat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/21/2019
Entry Details
US Patent

TargetTyrosine-protein kinase JAK1 [850-1154](Human)
Galapagos

US Patent
LigandChemical structure of BindingDB Monomer ID 348969BDBM348969(N-(5-(4-(4-(4- chlorophenyl)piperidine-1- carbonyl...)
Affinity DataIC50: 100nMAssay Description:Recombinant human JAK1 catalytic domain (amino acids 850-1154; catalog number 08-144) was purchased from Carna Biosciences. 10 ng of JAK1 was incubat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/21/2019
Entry Details
US Patent

TargetTyrosine-protein kinase JAK3 [781-1124](Human)
Galapagos

US Patent
LigandChemical structure of BindingDB Monomer ID 349193BDBM349193(Cyclopropanecarboxylic acid {5-[4-(3-cyano-azetidi...)
Affinity DataIC50: 100nMAssay Description:Recombinant human JAK3 catalytic domain (amino acids 781-1124; catalog number PV3855) was purchased from Invitrogen. 0.025 mU of JAK3 was incubated w...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/21/2019
Entry Details
US Patent

TargetTyrosine-protein kinase JAK3 [781-1124](Human)
Galapagos

US Patent
LigandChemical structure of BindingDB Monomer ID 349073BDBM349073(5-{4-[2-(Cyclopropanecarbonyl-amino)-[1,2,4]triazo...)
Affinity DataIC50: 100nMAssay Description:Recombinant human JAK3 catalytic domain (amino acids 781-1124; catalog number PV3855) was purchased from Invitrogen. 0.025 mU of JAK3 was incubated w...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/21/2019
Entry Details
US Patent

TargetTyrosine-protein kinase JAK3 [781-1124](Human)
Galapagos

US Patent
LigandChemical structure of BindingDB Monomer ID 103727BDBM103727(US8563545, 1 | US10112907, Example 00033 | US10206...)
Affinity DataIC50: 100nMAssay Description:Recombinant human JAK3 catalytic domain (amino acids 781-1124; catalog number PV3855) was purchased from Invitrogen. 0.025 mU of JAK3 was incubated w...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/21/2019
Entry Details
US Patent

TargetTyrosine-protein kinase JAK1 [850-1154](Human)
Galapagos

US Patent
LigandChemical structure of BindingDB Monomer ID 348957BDBM348957(N-(5-(4-(4-methylpiperazine- 1-carbonyl)phenyl)- [...)
Affinity DataIC50: 100nMAssay Description:Recombinant human JAK1 catalytic domain (amino acids 850-1154; catalog number 08-144) was purchased from Carna Biosciences. 10 ng of JAK1 was incubat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/21/2019
Entry Details
US Patent

TargetTyrosine-protein kinase JAK1 [850-1154](Human)
Galapagos

US Patent
LigandChemical structure of BindingDB Monomer ID 348960BDBM348960(N-(5-(4-(4-benzoylpiperidine- 1-carbonyl)phenyl)- ...)
Affinity DataIC50: 100nMAssay Description:Recombinant human JAK1 catalytic domain (amino acids 850-1154; catalog number 08-144) was purchased from Carna Biosciences. 10 ng of JAK1 was incubat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/21/2019
Entry Details
US Patent

TargetTyrosine-protein kinase JAK3 [781-1124](Human)
Galapagos

US Patent
LigandChemical structure of BindingDB Monomer ID 349137BDBM349137(Cyclopropanecarboxylic acid (5-[4-(3,3-difluoro- p...)
Affinity DataIC50: 100nMAssay Description:Recombinant human JAK3 catalytic domain (amino acids 781-1124; catalog number PV3855) was purchased from Invitrogen. 0.025 mU of JAK3 was incubated w...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/21/2019
Entry Details
US Patent

TargetTyrosine-protein kinase JAK1 [850-1154](Human)
Galapagos

US Patent
LigandChemical structure of BindingDB Monomer ID 348961BDBM348961(N-(5-(4-(4-benzyl-1,4- diazepane-1-carbonyl)phenyl...)
Affinity DataIC50: 100nMAssay Description:Recombinant human JAK1 catalytic domain (amino acids 850-1154; catalog number 08-144) was purchased from Carna Biosciences. 10 ng of JAK1 was incubat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/21/2019
Entry Details
US Patent

TargetTyrosine-protein kinase JAK1 [850-1154](Human)
Galapagos

US Patent
LigandChemical structure of BindingDB Monomer ID 348958BDBM348958(N-(5-(4- (benzylamino)phenyl)- [1,2,4]triazolo[1,5...)
Affinity DataIC50: 100nMAssay Description:Recombinant human JAK1 catalytic domain (amino acids 850-1154; catalog number 08-144) was purchased from Carna Biosciences. 10 ng of JAK1 was incubat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/21/2019
Entry Details
US Patent

TargetTyrosine-protein kinase JAK3 [781-1124](Human)
Galapagos

US Patent
LigandChemical structure of BindingDB Monomer ID 103737BDBM103737(US8563545, 11 | US10206907, Compound 234 | US11000...)
Affinity DataIC50: 100nMAssay Description:Recombinant human JAK3 catalytic domain (amino acids 781-1124; catalog number PV3855) was purchased from Invitrogen. 0.025 mU of JAK3 was incubated w...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/21/2019
Entry Details
US Patent

TargetTyrosine-protein kinase JAK1 [850-1154](Human)
Galapagos

US Patent
LigandChemical structure of BindingDB Monomer ID 348980BDBM348980(N-(5-(4-(2-(1H-pyrazol-1- yl)ethyl1H-pyrazol-1- yl...)
Affinity DataIC50: 100nMAssay Description:Recombinant human JAK1 catalytic domain (amino acids 850-1154; catalog number 08-144) was purchased from Carna Biosciences. 10 ng of JAK1 was incubat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/21/2019
Entry Details
US Patent

TargetTyrosine-protein kinase JAK1 [850-1154](Human)
Galapagos

US Patent
LigandChemical structure of BindingDB Monomer ID 348981BDBM348981(N-(5-(4-((1,2,4-oxadiazol-3- yl)methoxy)phenyl)- [...)
Affinity DataIC50: 100nMAssay Description:Recombinant human JAK1 catalytic domain (amino acids 850-1154; catalog number 08-144) was purchased from Carna Biosciences. 10 ng of JAK1 was incubat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/21/2019
Entry Details
US Patent

TargetTyrosine-protein kinase JAK1 [850-1154](Human)
Galapagos

US Patent
LigandChemical structure of BindingDB Monomer ID 348978BDBM348978(4-(2- (cyclopropanecarboxamido)- [1,2,4]triazolo[1...)
Affinity DataIC50: 100nMAssay Description:Recombinant human JAK1 catalytic domain (amino acids 850-1154; catalog number 08-144) was purchased from Carna Biosciences. 10 ng of JAK1 was incubat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/21/2019
Entry Details
US Patent

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