Compile Data Set for Download or QSAR
Report error Found 118 Enz. Inhib. hit(s) with all data for entry = 2224
TargetTryptophan 5-hydroxylase 2(Human)
Max-DelbrÜCk-Centrum FÜR Molekulare Medizin

US Patent
LigandChemical structure of BindingDB Monomer ID 357735BDBM357735(KM-05-193/(I-209) | US10214530, Example 27)
Affinity DataIC50: 14nMAssay Description:These compounds according to the afore-mentioned examples were tested for tryptophan hydroxylase (TPH) inhibitory activity in a fluorescence-based in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/20/2019
Entry Details
US Patent

TargetTryptophan 5-hydroxylase 2(Human)
Max-DelbrÜCk-Centrum FÜR Molekulare Medizin

US Patent
LigandChemical structure of BindingDB Monomer ID 357737BDBM357737(KM-05-166/(I-206) | US10214530, Example 24)
Affinity DataIC50: 14nMAssay Description:These compounds according to the afore-mentioned examples were tested for tryptophan hydroxylase (TPH) inhibitory activity in a fluorescence-based in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/20/2019
Entry Details
US Patent

TargetTryptophan 5-hydroxylase 2(Human)
Max-DelbrÜCk-Centrum FÜR Molekulare Medizin

US Patent
LigandChemical structure of BindingDB Monomer ID 357736BDBM357736(MW-01-157/(I-207) | US10214530, Example 25)
Affinity DataIC50: 20nMAssay Description:These compounds according to the afore-mentioned examples were tested for tryptophan hydroxylase (TPH) inhibitory activity in a fluorescence-based in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/20/2019
Entry Details
US Patent

TargetTryptophan 5-hydroxylase 2(Human)
Max-DelbrÜCk-Centrum FÜR Molekulare Medizin

US Patent
LigandChemical structure of BindingDB Monomer ID 357739BDBM357739(AG-01-128/(I-202) | US10214530, Example 18)
Affinity DataIC50: 20nMAssay Description:These compounds according to the afore-mentioned examples were tested for tryptophan hydroxylase (TPH) inhibitory activity in a fluorescence-based in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/20/2019
Entry Details
US Patent
PDB3D3D Structure (crystal)
TargetTryptophan 5-hydroxylase 2(Human)
Max-DelbrÜCk-Centrum FÜR Molekulare Medizin

US Patent
LigandChemical structure of BindingDB Monomer ID 357734BDBM357734(KM-05-185/(I-204) | US10214530, Example 21)
Affinity DataIC50: 20nMAssay Description:These compounds according to the afore-mentioned examples were tested for tryptophan hydroxylase (TPH) inhibitory activity in a fluorescence-based in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/20/2019
Entry Details
US Patent

TargetTryptophan 5-hydroxylase 2(Human)
Max-DelbrÜCk-Centrum FÜR Molekulare Medizin

US Patent
LigandChemical structure of BindingDB Monomer ID 357790BDBM357790(KM-05-179/(I-201) | US10214530, Example 14)
Affinity DataIC50: 40nMAssay Description:These compounds according to the afore-mentioned examples were tested for tryptophan hydroxylase (TPH) inhibitory activity in a fluorescence-based in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/20/2019
Entry Details
US Patent

TargetTryptophan 5-hydroxylase 2(Human)
Max-DelbrÜCk-Centrum FÜR Molekulare Medizin

US Patent
LigandChemical structure of BindingDB Monomer ID 357743BDBM357743(MW-01-139/(I-46) | US10214530, Example 52)
Affinity DataIC50: 40nMAssay Description:These compounds according to the afore-mentioned examples were tested for tryptophan hydroxylase (TPH) inhibitory activity in a fluorescence-based in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/20/2019
Entry Details
US Patent

TargetTryptophan 5-hydroxylase 2(Human)
Max-DelbrÜCk-Centrum FÜR Molekulare Medizin

US Patent
LigandChemical structure of BindingDB Monomer ID 357741BDBM357741(MW-01-153/(I-47) | US10214530, Example 53)
Affinity DataIC50: 50nMAssay Description:These compounds according to the afore-mentioned examples were tested for tryptophan hydroxylase (TPH) inhibitory activity in a fluorescence-based in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/20/2019
Entry Details
US Patent

TargetTryptophan 5-hydroxylase 2(Human)
Max-DelbrÜCk-Centrum FÜR Molekulare Medizin

US Patent
LigandChemical structure of BindingDB Monomer ID 357747BDBM357747(KM-05-173/(I-203) | US10214530, Example 20)
Affinity DataIC50: 50nMAssay Description:These compounds according to the afore-mentioned examples were tested for tryptophan hydroxylase (TPH) inhibitory activity in a fluorescence-based in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/20/2019
Entry Details
US Patent

TargetTryptophan 5-hydroxylase 2(Human)
Max-DelbrÜCk-Centrum FÜR Molekulare Medizin

US Patent
LigandChemical structure of BindingDB Monomer ID 357740BDBM357740(KM-05-139/(I-23) | US10214530, Example 23)
Affinity DataIC50: 50nMAssay Description:These compounds according to the afore-mentioned examples were tested for tryptophan hydroxylase (TPH) inhibitory activity in a fluorescence-based in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/20/2019
Entry Details
US Patent

TargetTryptophan 5-hydroxylase 2(Human)
Max-DelbrÜCk-Centrum FÜR Molekulare Medizin

US Patent
LigandChemical structure of BindingDB Monomer ID 357738BDBM357738(KM-05-130/(I-19) | US10214530, Example 19)
Affinity DataIC50: 60nMAssay Description:These compounds according to the afore-mentioned examples were tested for tryptophan hydroxylase (TPH) inhibitory activity in a fluorescence-based in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/20/2019
Entry Details
US Patent

TargetTryptophan 5-hydroxylase 2(Human)
Max-DelbrÜCk-Centrum FÜR Molekulare Medizin

US Patent
LigandChemical structure of BindingDB Monomer ID 357753BDBM357753(KM-05-174/(I-205) | US10214530, Example 22)
Affinity DataIC50: 60nMAssay Description:These compounds according to the afore-mentioned examples were tested for tryptophan hydroxylase (TPH) inhibitory activity in a fluorescence-based in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/20/2019
Entry Details
US Patent

TargetTryptophan 5-hydroxylase 2(Human)
Max-DelbrÜCk-Centrum FÜR Molekulare Medizin

US Patent
LigandChemical structure of BindingDB Monomer ID 357745BDBM357745(KM-05-125/(I-13) | US10214530, Example 13)
Affinity DataIC50: 70nMAssay Description:These compounds according to the afore-mentioned examples were tested for tryptophan hydroxylase (TPH) inhibitory activity in a fluorescence-based in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/20/2019
Entry Details
US Patent

TargetTryptophan 5-hydroxylase 2(Human)
Max-DelbrÜCk-Centrum FÜR Molekulare Medizin

US Patent
LigandChemical structure of BindingDB Monomer ID 357744BDBM357744(KM-05-80/(I-1) | US10214530, Example 1)
Affinity DataIC50: 70nMAssay Description:These compounds according to the afore-mentioned examples were tested for tryptophan hydroxylase (TPH) inhibitory activity in a fluorescence-based in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/20/2019
Entry Details
US Patent

TargetTryptophan 5-hydroxylase 2(Human)
Max-DelbrÜCk-Centrum FÜR Molekulare Medizin

US Patent
LigandChemical structure of BindingDB Monomer ID 357749BDBM357749(KM-06-11/(I-210) | US10214530, Example 28)
Affinity DataIC50: 90nMAssay Description:These compounds according to the afore-mentioned examples were tested for tryptophan hydroxylase (TPH) inhibitory activity in a fluorescence-based in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/20/2019
Entry Details
US Patent

TargetTryptophan 5-hydroxylase 2(Human)
Max-DelbrÜCk-Centrum FÜR Molekulare Medizin

US Patent
LigandChemical structure of BindingDB Monomer ID 357748BDBM357748(KM-05-89/(I-2) | US10214530, Example 2)
Affinity DataIC50: 100nMAssay Description:These compounds according to the afore-mentioned examples were tested for tryptophan hydroxylase (TPH) inhibitory activity in a fluorescence-based in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/20/2019
Entry Details
US Patent

TargetTryptophan 5-hydroxylase 2(Human)
Max-DelbrÜCk-Centrum FÜR Molekulare Medizin

US Patent
LigandChemical structure of BindingDB Monomer ID 357746BDBM357746(KM-06-20/(I-211) | US10214530, Example 29)
Affinity DataIC50: 100nMAssay Description:These compounds according to the afore-mentioned examples were tested for tryptophan hydroxylase (TPH) inhibitory activity in a fluorescence-based in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/20/2019
Entry Details
US Patent

TargetTryptophan 5-hydroxylase 2(Human)
Max-DelbrÜCk-Centrum FÜR Molekulare Medizin

US Patent
LigandChemical structure of BindingDB Monomer ID 357750BDBM357750(KM-05-135/(I-15) | US10214530, Example 15)
Affinity DataIC50: 140nMAssay Description:These compounds according to the afore-mentioned examples were tested for tryptophan hydroxylase (TPH) inhibitory activity in a fluorescence-based in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/20/2019
Entry Details
US Patent

TargetTryptophan 5-hydroxylase 2(Human)
Max-DelbrÜCk-Centrum FÜR Molekulare Medizin

US Patent
LigandChemical structure of BindingDB Monomer ID 357751BDBM357751(KM-05-128/(I-17) | US10214530, Example 17)
Affinity DataIC50: 140nMAssay Description:These compounds according to the afore-mentioned examples were tested for tryptophan hydroxylase (TPH) inhibitory activity in a fluorescence-based in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/20/2019
Entry Details
US Patent

TargetTryptophan 5-hydroxylase 2(Human)
Max-DelbrÜCk-Centrum FÜR Molekulare Medizin

US Patent
LigandChemical structure of BindingDB Monomer ID 357754BDBM357754(KM-05-60/(I-10) | US10214530, Example 10)
Affinity DataIC50: 170nMAssay Description:These compounds according to the afore-mentioned examples were tested for tryptophan hydroxylase (TPH) inhibitory activity in a fluorescence-based in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/20/2019
Entry Details
US Patent

TargetTryptophan 5-hydroxylase 2(Human)
Max-DelbrÜCk-Centrum FÜR Molekulare Medizin

US Patent
LigandChemical structure of BindingDB Monomer ID 357760BDBM357760(KM-05-50/(I-4) | US10214530, Example 4)
Affinity DataIC50: 170nMAssay Description:These compounds according to the afore-mentioned examples were tested for tryptophan hydroxylase (TPH) inhibitory activity in a fluorescence-based in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/20/2019
Entry Details
US Patent

TargetTryptophan 5-hydroxylase 2(Human)
Max-DelbrÜCk-Centrum FÜR Molekulare Medizin

US Patent
LigandChemical structure of BindingDB Monomer ID 357755BDBM357755(KM-05-93/(I-9) | US10214530, Example 9)
Affinity DataIC50: 190nMAssay Description:These compounds according to the afore-mentioned examples were tested for tryptophan hydroxylase (TPH) inhibitory activity in a fluorescence-based in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/20/2019
Entry Details
US Patent

TargetTryptophan 5-hydroxylase 2(Human)
Max-DelbrÜCk-Centrum FÜR Molekulare Medizin

US Patent
LigandChemical structure of BindingDB Monomer ID 357752BDBM357752(KM-05-126/(I-12) | US10214530, Example 12)
Affinity DataIC50: 230nMAssay Description:These compounds according to the afore-mentioned examples were tested for tryptophan hydroxylase (TPH) inhibitory activity in a fluorescence-based in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/20/2019
Entry Details
US Patent

TargetTryptophan 5-hydroxylase 2(Human)
Max-DelbrÜCk-Centrum FÜR Molekulare Medizin

US Patent
LigandChemical structure of BindingDB Monomer ID 357756BDBM357756(KM480/(I-41) | US10214530, Example 47)
Affinity DataIC50: 230nMAssay Description:These compounds according to the afore-mentioned examples were tested for tryptophan hydroxylase (TPH) inhibitory activity in a fluorescence-based in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/20/2019
Entry Details
US Patent

TargetTryptophan 5-hydroxylase 1(Human)
Max-DelbrÜCk-Centrum FÜR Molekulare Medizin

US Patent
LigandChemical structure of BindingDB Monomer ID 357734BDBM357734(KM-05-185/(I-204) | US10214530, Example 21)
Affinity DataIC50: 240nMAssay Description:These compounds according to the afore-mentioned examples were tested for tryptophan hydroxylase (TPH) inhibitory activity in a fluorescence-based in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/20/2019
Entry Details
US Patent

TargetTryptophan 5-hydroxylase 2(Human)
Max-DelbrÜCk-Centrum FÜR Molekulare Medizin

US Patent
LigandChemical structure of BindingDB Monomer ID 357757BDBM357757(KM-05-55 Fr16-17/(I-7) | US10214530, Example 7)
Affinity DataIC50: 290nMAssay Description:These compounds according to the afore-mentioned examples were tested for tryptophan hydroxylase (TPH) inhibitory activity in a fluorescence-based in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/20/2019
Entry Details
US Patent

TargetTryptophan 5-hydroxylase 1(Human)
Max-DelbrÜCk-Centrum FÜR Molekulare Medizin

US Patent
LigandChemical structure of BindingDB Monomer ID 357735BDBM357735(KM-05-193/(I-209) | US10214530, Example 27)
Affinity DataIC50: 300nMAssay Description:These compounds according to the afore-mentioned examples were tested for tryptophan hydroxylase (TPH) inhibitory activity in a fluorescence-based in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/20/2019
Entry Details
US Patent
PDB3D3D Structure (crystal)
TargetTryptophan 5-hydroxylase 1(Human)
Max-DelbrÜCk-Centrum FÜR Molekulare Medizin

US Patent
LigandChemical structure of BindingDB Monomer ID 357736BDBM357736(MW-01-157/(I-207) | US10214530, Example 25)
Affinity DataIC50: 350nMAssay Description:These compounds according to the afore-mentioned examples were tested for tryptophan hydroxylase (TPH) inhibitory activity in a fluorescence-based in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/20/2019
Entry Details
US Patent

TargetTryptophan 5-hydroxylase 1(Human)
Max-DelbrÜCk-Centrum FÜR Molekulare Medizin

US Patent
LigandChemical structure of BindingDB Monomer ID 357737BDBM357737(KM-05-166/(I-206) | US10214530, Example 24)
Affinity DataIC50: 360nMAssay Description:These compounds according to the afore-mentioned examples were tested for tryptophan hydroxylase (TPH) inhibitory activity in a fluorescence-based in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/20/2019
Entry Details
US Patent

TargetTryptophan 5-hydroxylase 1(Human)
Max-DelbrÜCk-Centrum FÜR Molekulare Medizin

US Patent
LigandChemical structure of BindingDB Monomer ID 357738BDBM357738(KM-05-130/(I-19) | US10214530, Example 19)
Affinity DataIC50: 410nMAssay Description:These compounds according to the afore-mentioned examples were tested for tryptophan hydroxylase (TPH) inhibitory activity in a fluorescence-based in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/20/2019
Entry Details
US Patent

TargetTryptophan 5-hydroxylase 2(Human)
Max-DelbrÜCk-Centrum FÜR Molekulare Medizin

US Patent
LigandChemical structure of BindingDB Monomer ID 357765BDBM357765(KM422/(I-25) | US10214530, Example 31)
Affinity DataIC50: 430nMAssay Description:These compounds according to the afore-mentioned examples were tested for tryptophan hydroxylase (TPH) inhibitory activity in a fluorescence-based in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/20/2019
Entry Details
US Patent

TargetTryptophan 5-hydroxylase 1(Human)
Max-DelbrÜCk-Centrum FÜR Molekulare Medizin

US Patent
LigandChemical structure of BindingDB Monomer ID 357739BDBM357739(AG-01-128/(I-202) | US10214530, Example 18)
Affinity DataIC50: 430nMAssay Description:These compounds according to the afore-mentioned examples were tested for tryptophan hydroxylase (TPH) inhibitory activity in a fluorescence-based in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/20/2019
Entry Details
US Patent
PDB3D3D Structure (crystal)
TargetTryptophan 5-hydroxylase 2(Human)
Max-DelbrÜCk-Centrum FÜR Molekulare Medizin

US Patent
LigandChemical structure of BindingDB Monomer ID 357759BDBM357759(KM-05-127/(I-16) | US10214530, Example 16)
Affinity DataIC50: 450nMAssay Description:These compounds according to the afore-mentioned examples were tested for tryptophan hydroxylase (TPH) inhibitory activity in a fluorescence-based in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/20/2019
Entry Details
US Patent

TargetTryptophan 5-hydroxylase 2(Human)
Max-DelbrÜCk-Centrum FÜR Molekulare Medizin

US Patent
LigandChemical structure of BindingDB Monomer ID 357769BDBM357769(KM446/(I-35) | US10214530, Example 41)
Affinity DataIC50: 490nMAssay Description:These compounds according to the afore-mentioned examples were tested for tryptophan hydroxylase (TPH) inhibitory activity in a fluorescence-based in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/20/2019
Entry Details
US Patent

TargetTryptophan 5-hydroxylase 2(Human)
Max-DelbrÜCk-Centrum FÜR Molekulare Medizin

US Patent
LigandChemical structure of BindingDB Monomer ID 357762BDBM357762(KM430/(I-31) | US10214530, Example 37)
Affinity DataIC50: 490nMAssay Description:These compounds according to the afore-mentioned examples were tested for tryptophan hydroxylase (TPH) inhibitory activity in a fluorescence-based in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/20/2019
Entry Details
US Patent

TargetTryptophan 5-hydroxylase 2(Human)
Max-DelbrÜCk-Centrum FÜR Molekulare Medizin

US Patent
LigandChemical structure of BindingDB Monomer ID 357770BDBM357770(KM424/(I-27) | US10214530, Example 33)
Affinity DataIC50: 570nMAssay Description:These compounds according to the afore-mentioned examples were tested for tryptophan hydroxylase (TPH) inhibitory activity in a fluorescence-based in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/20/2019
Entry Details
US Patent

TargetTryptophan 5-hydroxylase 1(Human)
Max-DelbrÜCk-Centrum FÜR Molekulare Medizin

US Patent
LigandChemical structure of BindingDB Monomer ID 357740BDBM357740(KM-05-139/(I-23) | US10214530, Example 23)
Affinity DataIC50: 590nMAssay Description:These compounds according to the afore-mentioned examples were tested for tryptophan hydroxylase (TPH) inhibitory activity in a fluorescence-based in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/20/2019
Entry Details
US Patent

TargetTryptophan 5-hydroxylase 2(Human)
Max-DelbrÜCk-Centrum FÜR Molekulare Medizin

US Patent
LigandChemical structure of BindingDB Monomer ID 357761BDBM357761(KM-05-55 Fr10-12/(l-6) | US10214530, Example 6)
Affinity DataIC50: 690nMAssay Description:These compounds according to the afore-mentioned examples were tested for tryptophan hydroxylase (TPH) inhibitory activity in a fluorescence-based in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/20/2019
Entry Details
US Patent

TargetTryptophan 5-hydroxylase 2(Human)
Max-DelbrÜCk-Centrum FÜR Molekulare Medizin

US Patent
LigandChemical structure of BindingDB Monomer ID 357742BDBM357742(US10214530, LX1031 | US11028104, Example LX1031)
Affinity DataIC50: 730nMAssay Description:These compounds according to the afore-mentioned examples were tested for tryptophan hydroxylase (TPH) inhibitory activity in a fluorescence-based in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/20/2019
Entry Details
US Patent

TargetTryptophan 5-hydroxylase 2(Human)
Max-DelbrÜCk-Centrum FÜR Molekulare Medizin

US Patent
LigandChemical structure of BindingDB Monomer ID 357758BDBM357758(KM-05-100/(I-11) | US10214530, Example 11)
Affinity DataIC50: 740nMAssay Description:These compounds according to the afore-mentioned examples were tested for tryptophan hydroxylase (TPH) inhibitory activity in a fluorescence-based in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/20/2019
Entry Details
US Patent

TargetTryptophan 5-hydroxylase 2(Human)
Max-DelbrÜCk-Centrum FÜR Molekulare Medizin

US Patent
LigandChemical structure of BindingDB Monomer ID 357777BDBM357777(KM-05-52/(I-5) | US10214530, Example 5)
Affinity DataIC50: 760nMAssay Description:These compounds according to the afore-mentioned examples were tested for tryptophan hydroxylase (TPH) inhibitory activity in a fluorescence-based in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/20/2019
Entry Details
US Patent

TargetTryptophan 5-hydroxylase 1(Human)
Max-DelbrÜCk-Centrum FÜR Molekulare Medizin

US Patent
LigandChemical structure of BindingDB Monomer ID 357741BDBM357741(MW-01-153/(I-47) | US10214530, Example 53)
Affinity DataIC50: 760nMAssay Description:These compounds according to the afore-mentioned examples were tested for tryptophan hydroxylase (TPH) inhibitory activity in a fluorescence-based in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/20/2019
Entry Details
US Patent

TargetTryptophan 5-hydroxylase 1(Human)
Max-DelbrÜCk-Centrum FÜR Molekulare Medizin

US Patent
LigandChemical structure of BindingDB Monomer ID 357742BDBM357742(US10214530, LX1031 | US11028104, Example LX1031)
Affinity DataIC50: 770nMAssay Description:These compounds according to the afore-mentioned examples were tested for tryptophan hydroxylase (TPH) inhibitory activity in a fluorescence-based in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/20/2019
Entry Details
US Patent

TargetTryptophan 5-hydroxylase 2(Human)
Max-DelbrÜCk-Centrum FÜR Molekulare Medizin

US Patent
LigandChemical structure of BindingDB Monomer ID 357763BDBM357763(KM-05-16/(I-3) | US10214530, Example 3)
Affinity DataIC50: 820nMAssay Description:These compounds according to the afore-mentioned examples were tested for tryptophan hydroxylase (TPH) inhibitory activity in a fluorescence-based in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/20/2019
Entry Details
US Patent

TargetTryptophan 5-hydroxylase 1(Human)
Max-DelbrÜCk-Centrum FÜR Molekulare Medizin

US Patent
LigandChemical structure of BindingDB Monomer ID 357743BDBM357743(MW-01-139/(I-46) | US10214530, Example 52)
Affinity DataIC50: 830nMAssay Description:These compounds according to the afore-mentioned examples were tested for tryptophan hydroxylase (TPH) inhibitory activity in a fluorescence-based in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/20/2019
Entry Details
US Patent

TargetTryptophan 5-hydroxylase 2(Human)
Max-DelbrÜCk-Centrum FÜR Molekulare Medizin

US Patent
LigandChemical structure of BindingDB Monomer ID 357766BDBM357766(KM477/(I-40) | US10214530, Example 46)
Affinity DataIC50: 830nMAssay Description:These compounds according to the afore-mentioned examples were tested for tryptophan hydroxylase (TPH) inhibitory activity in a fluorescence-based in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/20/2019
Entry Details
US Patent

TargetTryptophan 5-hydroxylase 1(Human)
Max-DelbrÜCk-Centrum FÜR Molekulare Medizin

US Patent
LigandChemical structure of BindingDB Monomer ID 357744BDBM357744(KM-05-80/(I-1) | US10214530, Example 1)
Affinity DataIC50: 850nMAssay Description:These compounds according to the afore-mentioned examples were tested for tryptophan hydroxylase (TPH) inhibitory activity in a fluorescence-based in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/20/2019
Entry Details
US Patent
PDB3D3D Structure (crystal)
TargetTryptophan 5-hydroxylase 2(Human)
Max-DelbrÜCk-Centrum FÜR Molekulare Medizin

US Patent
LigandChemical structure of BindingDB Monomer ID 357771BDBM357771(KM-05-180/(I-208) | US10214530, Example 26)
Affinity DataIC50: 850nMAssay Description:These compounds according to the afore-mentioned examples were tested for tryptophan hydroxylase (TPH) inhibitory activity in a fluorescence-based in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/20/2019
Entry Details
US Patent

TargetTryptophan 5-hydroxylase 2(Human)
Max-DelbrÜCk-Centrum FÜR Molekulare Medizin

US Patent
LigandChemical structure of BindingDB Monomer ID 357772BDBM357772(KM447/(I-36) | US10214530, Example 42)
Affinity DataIC50: 900nMAssay Description:These compounds according to the afore-mentioned examples were tested for tryptophan hydroxylase (TPH) inhibitory activity in a fluorescence-based in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/20/2019
Entry Details
US Patent

TargetTryptophan 5-hydroxylase 2(Human)
Max-DelbrÜCk-Centrum FÜR Molekulare Medizin

US Patent
LigandChemical structure of BindingDB Monomer ID 357764BDBM357764(KM406/(I-24) | US10214530, Example 30)
Affinity DataIC50: 920nMAssay Description:These compounds according to the afore-mentioned examples were tested for tryptophan hydroxylase (TPH) inhibitory activity in a fluorescence-based in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/20/2019
Entry Details
US Patent

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