Compile Data Set for Download or QSAR
Report error Found 528 Enz. Inhib. hit(s) with all data for entry = 2338
LigandChemical structure of BindingDB Monomer ID 362018BDBM362018(US10221197, Compound 12)
Affinity DataIC50: 300nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/27/2019
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 362014BDBM362014(US10221197, Compound 8)
Affinity DataIC50: 400nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/27/2019
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 362008BDBM362008(US10221197, Compound 2)
Affinity DataIC50: 500nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/27/2019
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 362025BDBM362025(US10221197, Compound 38 | US10221197, Compound 18)
Affinity DataIC50: 500nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/27/2019
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 362026BDBM362026(US10221197, Compound 39 | US10221197, Compound 19)
Affinity DataIC50: 500nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/27/2019
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 362027BDBM362027(US10221197, Compound 40 | US10221197, Compound 20)
Affinity DataIC50: 600nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/27/2019
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 362020BDBM362020(US10221197, Compound 13)
Affinity DataIC50: 600nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/27/2019
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 362015BDBM362015(US10221197, Compound 9)
Affinity DataIC50: 600nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/27/2019
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 362029BDBM362029(US10221197, Compound 22)
Affinity DataIC50: 700nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/27/2019
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 362007BDBM362007(US10221197, Compound 1)
Affinity DataIC50: 700nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/27/2019
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 362040BDBM362040((S)-3-(2-(1-((2,6-diamino-5-cyanopyrimidin-4-yl)am...)
Affinity DataIC50: 800nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/27/2019
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 362048BDBM362048((S)-3-(5,8-dichloro-2-(1-((2,6-diamino-5-cyanopyri...)
Affinity DataIC50: 800nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/27/2019
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 362009BDBM362009(US10221197, Compound 3)
Affinity DataIC50: 800nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/27/2019
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 362087BDBM362087((S)—N-((3-(5-chloro-4-oxo-2-(1-(thiazolo[5,4-...)
Affinity DataIC50: 900nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/27/2019
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 362010BDBM362010(US10221197, Compound 4)
Affinity DataIC50: 1.00E+3nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/27/2019
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 362022BDBM362022(US10221197, Compound 15)
Affinity DataIC50: 1.00E+3nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/27/2019
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 362025BDBM362025(US10221197, Compound 38 | US10221197, Compound 18)
Affinity DataIC50: 1.00E+3nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/27/2019
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 362169BDBM362169(US10221197, Compound 164 | (S)-5-(5-chloro-2-(cycl...)
Affinity DataIC50: 1.00E+3nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/27/2019
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 362167BDBM362167((S)-3-(5-chloro-2-(cyclopropyl((2,6-diamino-5-cyan...)
Affinity DataIC50: 1.00E+3nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/27/2019
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 362168BDBM362168((S)-3-(5-chloro-2-(cyclopropyl((2,6-diamino-5-chlo...)
Affinity DataIC50: 1.00E+3nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/27/2019
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 362021BDBM362021(US10221197, Compound 14)
Affinity DataIC50: 1.00E+3nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/27/2019
Entry Details
US Patent

TargetPhosphatidylinositol 3-kinase regulatory subunit beta(Human)
Gilead Sciences

US Patent
LigandChemical structure of BindingDB Monomer ID 362107BDBM362107(US10221197, Compound 113 | (S)-1-(3-(2-(1-((6-amin...)
Affinity DataIC50: 1.00E+3nMAssay Description:TR-FRET monitored the formation of 3,4,5-inositol triphosphate molecule that competed with fluorescently labeled PIP3 for binding to the GRP-1 plecks...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/27/2019
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 362032BDBM362032((S)-3-(2-(1-((2-amino-5-cyano-6-(difluoromethyl)py...)
Affinity DataIC50: 1.00E+3nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/27/2019
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 362031BDBM362031((S)-3-(2-(1-((2-amino-5-cyano-6-(difluoromethyl)py...)
Affinity DataIC50: 1.00E+3nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/27/2019
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 362042BDBM362042((S)-3-(2-(cyclopropyl((2,6-diamino-5-cyanopyrimidi...)
Affinity DataIC50: 1.00E+3nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/27/2019
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 362016BDBM362016(US10221197, Compound 10)
Affinity DataIC50: 1.00E+3nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/27/2019
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 362036BDBM362036((S)-3-(8-chloro-2-(1-((2,6-diamino-5-cyanopyrimidi...)
Affinity DataIC50: 1.00E+3nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/27/2019
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 362099BDBM362099((S)-1-(3-(2-(1-((6-amino-5-(pyridin-2-yl)ethynyl)p...)
Affinity DataIC50: 1.00E+3nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/27/2019
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 362013BDBM362013(US10221197, Compound 7)
Affinity DataIC50: 1.00E+3nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/27/2019
Entry Details
US Patent

TargetPhosphatidylinositol 3-kinase regulatory subunit beta(Human)
Gilead Sciences

US Patent
LigandChemical structure of BindingDB Monomer ID 362169BDBM362169(US10221197, Compound 164 | (S)-5-(5-chloro-2-(cycl...)
Affinity DataIC50: 2.00E+3nMAssay Description:TR-FRET monitored the formation of 3,4,5-inositol triphosphate molecule that competed with fluorescently labeled PIP3 for binding to the GRP-1 plecks...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/27/2019
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 362011BDBM362011(US10221197, Compound 6 | US10221197, Compound 5)
Affinity DataIC50: 2.00E+3nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/27/2019
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 362169BDBM362169(US10221197, Compound 164 | (S)-5-(5-chloro-2-(cycl...)
Affinity DataIC50: 2.00E+3nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/27/2019
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 362086BDBM362086((S)—N-((3-(2-(1-((6-amino-5-cyanopyrimidin-4-...)
Affinity DataIC50: 2.00E+3nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/27/2019
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 362077BDBM362077(US10221197, Compound 70)
Affinity DataIC50: 2.00E+3nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/27/2019
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 362024BDBM362024(US10221197, Compound 17)
Affinity DataIC50: 2.00E+3nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/27/2019
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 362088BDBM362088((S)—N-((3-(2-(1-((6-amino-5-cyanopyrimidin-4-...)
Affinity DataIC50: 2.00E+3nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/27/2019
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 362023BDBM362023(US10221197, Compound 16)
Affinity DataIC50: 2.00E+3nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/27/2019
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 362162BDBM362162(1-(3-(5-chloro-4-oxo-2-(1-(thiazolo[5,4-d]pyrimidi...)
Affinity DataIC50: 2.00E+3nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/27/2019
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 362034BDBM362034((S)-3-(8-chloro-2-(cyclopropyl((2,6-diamino-5-cyan...)
Affinity DataIC50: 2.00E+3nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/27/2019
Entry Details
US Patent

TargetPhosphatidylinositol 3-kinase regulatory subunit beta(Human)
Gilead Sciences

US Patent
LigandChemical structure of BindingDB Monomer ID 362167BDBM362167((S)-3-(5-chloro-2-(cyclopropyl((2,6-diamino-5-cyan...)
Affinity DataIC50: 2.00E+3nMAssay Description:TR-FRET monitored the formation of 3,4,5-inositol triphosphate molecule that competed with fluorescently labeled PIP3 for binding to the GRP-1 plecks...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/27/2019
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 362116BDBM362116((S)-1-(3-(2-(1-((6-amino-5-cyanopyrimidin-4-yl)ami...)
Affinity DataIC50: 2.00E+3nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/27/2019
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 362052BDBM362052((S)-1-(3-(2-(1-((6-amino-5-cyanopyrimidin-4-yl)ami...)
Affinity DataIC50: 2.00E+3nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/27/2019
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 362030BDBM362030((S)-3-(5-chloro-2-(1-((2,6-diamino-5-chloropyrimid...)
Affinity DataIC50: 2.00E+3nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/27/2019
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 362095BDBM362095((S)-1-(3-(2-(1-((6-amino-5-cyanopyrimidin-4-yl)ami...)
Affinity DataIC50: 2.00E+3nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/27/2019
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 362038BDBM362038((S)-3-(8-cyano-2-(1-((2,6-diamino-5-cyanopyrimidin...)
Affinity DataIC50: 2.00E+3nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/27/2019
Entry Details
US Patent

TargetPhosphatidylinositol 3-kinase regulatory subunit beta(Human)
Gilead Sciences

US Patent
LigandChemical structure of BindingDB Monomer ID 362014BDBM362014(US10221197, Compound 8)
Affinity DataIC50: 2.00E+3nMAssay Description:TR-FRET monitored the formation of 3,4,5-inositol triphosphate molecule that competed with fluorescently labeled PIP3 for binding to the GRP-1 plecks...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/27/2019
Entry Details
US Patent

TargetPhosphatidylinositol 3-kinase regulatory subunit beta(Human)
Gilead Sciences

US Patent
LigandChemical structure of BindingDB Monomer ID 362110BDBM362110((S)-1-(3-(2-(1-((6-amino-5-cyanopyrimidin-4-yl)ami...)
Affinity DataIC50: 2.00E+3nMAssay Description:TR-FRET monitored the formation of 3,4,5-inositol triphosphate molecule that competed with fluorescently labeled PIP3 for binding to the GRP-1 plecks...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/27/2019
Entry Details
US Patent

TargetPhosphatidylinositol 3-kinase regulatory subunit beta(Human)
Gilead Sciences

US Patent
LigandChemical structure of BindingDB Monomer ID 362015BDBM362015(US10221197, Compound 9)
Affinity DataIC50: 2.00E+3nMAssay Description:TR-FRET monitored the formation of 3,4,5-inositol triphosphate molecule that competed with fluorescently labeled PIP3 for binding to the GRP-1 plecks...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/27/2019
Entry Details
US Patent

TargetPhosphatidylinositol 3-kinase regulatory subunit beta(Human)
Gilead Sciences

US Patent
LigandChemical structure of BindingDB Monomer ID 362123BDBM362123((S)-1-(3-(2-(1-((6-amino-5-cyanopyrimidin-4-yl)ami...)
Affinity DataIC50: 2.00E+3nMAssay Description:TR-FRET monitored the formation of 3,4,5-inositol triphosphate molecule that competed with fluorescently labeled PIP3 for binding to the GRP-1 plecks...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/27/2019
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 362162BDBM362162(1-(3-(5-chloro-4-oxo-2-(1-(thiazolo[5,4-d]pyrimidi...)
Affinity DataIC50: 2.00E+3nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/27/2019
Entry Details
US Patent

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