Compile Data Set for Download or QSAR
Report error Found 104 Enz. Inhib. hit(s) with all data for entry = 2496
TargetNuclear receptor ROR-gamma(Human)
Pfizer

US Patent
LigandChemical structure of BindingDB Monomer ID 189904BDBM189904(US9670201, 29 (S)-3-cyano-N-(1-methyl-3-(1-(tetrah...)
Affinity DataIC50: 0.900nMAssay Description:The activity of compound of the invention can be determined by a co-activator recruitment by TR-FRET (time-resolved fluorescence resonance energy tra...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2019
Entry Details
US Patent

TargetNuclear receptor ROR-gamma(Human)
Pfizer

US Patent
LigandChemical structure of BindingDB Monomer ID 190325BDBM190325(US9670201, 81 3-cyano-N-(3-((3R,4R)-1-(cyclopentan...)
Affinity DataIC50: 1.20nMAssay Description:The activity of compound of the invention can be determined by a co-activator recruitment by TR-FRET (time-resolved fluorescence resonance energy tra...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2019
Entry Details
US Patent

TargetNuclear receptor ROR-gamma(Human)
Pfizer

US Patent
LigandChemical structure of BindingDB Monomer ID 189884BDBM189884(US9670201, 11 4-chloro-3-cyano-N-(3-(1-isobutyrylp...)
Affinity DataIC50: 1.5nMAssay Description:The activity of compound of the invention can be determined by a co-activator recruitment by TR-FRET (time-resolved fluorescence resonance energy tra...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2019
Entry Details
US Patent

TargetNuclear receptor ROR-gamma(Human)
Pfizer

US Patent
LigandChemical structure of BindingDB Monomer ID 368656BDBM368656(3-cyano-N-(3-((1R,5S,8r)-3-isobutyryl-3- azabicycl...)
Affinity DataIC50: 2.10nMAssay Description:The activity of compound of the invention can be determined by a co-activator recruitment by TR-FRET (time-resolved fluorescence resonance energy tra...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2019
Entry Details
US Patent

TargetNuclear receptor ROR-gamma(Human)
Pfizer

US Patent
LigandChemical structure of BindingDB Monomer ID 190346BDBM190346(US9670201, 95 3-cyano-N-(3-((2S,4R)-1-isobutyryl-2...)
Affinity DataIC50: 2.70nMAssay Description:The activity of compound of the invention can be determined by a co-activator recruitment by TR-FRET (time-resolved fluorescence resonance energy tra...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2019
Entry Details
US Patent

TargetNuclear receptor ROR-gamma(Human)
Pfizer

US Patent
LigandChemical structure of BindingDB Monomer ID 189895BDBM189895(US9670201, 22 (S)-3-cyano-N-(1-methyl-4-(trifluoro...)
Affinity DataIC50: 2.70nMAssay Description:The activity of compound of the invention can be determined by a co-activator recruitment by TR-FRET (time-resolved fluorescence resonance energy tra...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2019
Entry Details
US Patent

TargetNuclear receptor ROR-gamma(Human)
Pfizer

US Patent
LigandChemical structure of BindingDB Monomer ID 189905BDBM189905(US9670201, 30 (R)-3-cyano-4-methoxy-N-(1-methyl-4-...)
Affinity DataIC50: 2.80nMAssay Description:The activity of compound of the invention can be determined by a co-activator recruitment by TR-FRET (time-resolved fluorescence resonance energy tra...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2019
Entry Details
US Patent

TargetNuclear receptor ROR-gamma(Human)
Pfizer

US Patent
LigandChemical structure of BindingDB Monomer ID 189874BDBM189874(US9670201, 3 3-cyano-N-(3-(1-(cyclopentanecarbonyl...)
Affinity DataIC50: 3.20nMAssay Description:The activity of compound of the invention can be determined by a co-activator recruitment by TR-FRET (time-resolved fluorescence resonance energy tra...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2019
Entry Details
US Patent

TargetNuclear receptor ROR-gamma(Human)
Pfizer

US Patent
LigandChemical structure of BindingDB Monomer ID 189882BDBM189882(US9670201, 10 3-chloro-N-(3-(1-isobutyrylpiperidin...)
Affinity DataIC50: 3.5nMAssay Description:The activity of compound of the invention can be determined by a co-activator recruitment by TR-FRET (time-resolved fluorescence resonance energy tra...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2019
Entry Details
US Patent

TargetNuclear receptor ROR-gamma(Human)
Pfizer

US Patent
LigandChemical structure of BindingDB Monomer ID 189891BDBM189891(US9670201, 18 3-cyano-N-(3-(1-(2-cyclobutylacetyl)...)
Affinity DataIC50: 3.80nMAssay Description:The activity of compound of the invention can be determined by a co-activator recruitment by TR-FRET (time-resolved fluorescence resonance energy tra...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2019
Entry Details
US Patent

TargetNuclear receptor ROR-gamma(Human)
Pfizer

US Patent
LigandChemical structure of BindingDB Monomer ID 189888BDBM189888(US9670201, 15 3-cyano-N-(1-methyl-3-(1-(3-methylbu...)
Affinity DataIC50: 3.90nMAssay Description:The activity of compound of the invention can be determined by a co-activator recruitment by TR-FRET (time-resolved fluorescence resonance energy tra...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2019
Entry Details
US Patent

TargetNuclear receptor ROR-gamma(Human)
Pfizer

US Patent
LigandChemical structure of BindingDB Monomer ID 189873BDBM189873(US9670201, 2 3-cyano-N-(3-(1-(cyclopentanecarbonyl...)
Affinity DataIC50: 4nMAssay Description:The activity of compound of the invention can be determined by a co-activator recruitment by TR-FRET (time-resolved fluorescence resonance energy tra...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2019
Entry Details
US Patent

TargetNuclear receptor ROR-gamma(Human)
Pfizer

US Patent
LigandChemical structure of BindingDB Monomer ID 190324BDBM190324(US9670201, 80 3-cyano-N-(3-((3R,4R)-1-isobutyryl-3...)
Affinity DataIC50: 4.30nMAssay Description:The activity of compound of the invention can be determined by a co-activator recruitment by TR-FRET (time-resolved fluorescence resonance energy tra...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2019
Entry Details
US Patent

TargetNuclear receptor ROR-gamma(Human)
Pfizer

US Patent
LigandChemical structure of BindingDB Monomer ID 368615BDBM368615(US10227346, Example 36 | US10426135, Example 36)
Affinity DataIC50: 4.5nMAssay Description:The activity of compound of the invention can be determined by a co-activator recruitment by TR-FRET (time-resolved fluorescence resonance energy tra...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2019
Entry Details
US Patent

TargetNuclear receptor ROR-gamma(Human)
Pfizer

US Patent
LigandChemical structure of BindingDB Monomer ID 189918BDBM189918(US9670201, 41 (R)-5-chloro-N-(1,4-dimethyl-3-(1-(2...)
Affinity DataIC50: 4.5nMAssay Description:The activity of compound of the invention can be determined by a co-activator recruitment by TR-FRET (time-resolved fluorescence resonance energy tra...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2019
Entry Details
US Patent

TargetNuclear receptor ROR-gamma(Human)
Pfizer

US Patent
LigandChemical structure of BindingDB Monomer ID 189936BDBM189936(US9670201, 54 (R)-3-cyano-5-hydroxy-N-(1-methyl-4-...)
Affinity DataIC50: 4.70nMAssay Description:The activity of compound of the invention can be determined by a co-activator recruitment by TR-FRET (time-resolved fluorescence resonance energy tra...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2019
Entry Details
US Patent

TargetNuclear receptor ROR-gamma(Human)
Pfizer

US Patent
LigandChemical structure of BindingDB Monomer ID 189897BDBM189897(US9670201, 23 3-cyano-N-(3-(1-(cyclopentanecarbony...)
Affinity DataIC50: 4.70nMAssay Description:The activity of compound of the invention can be determined by a co-activator recruitment by TR-FRET (time-resolved fluorescence resonance energy tra...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2019
Entry Details
US Patent

TargetNuclear receptor ROR-gamma(Human)
Pfizer

US Patent
LigandChemical structure of BindingDB Monomer ID 189879BDBM189879(US9670201, 7 3-cyano-N-(3-(1-isobutyrylpiperidin-4...)
Affinity DataIC50: 4.90nMAssay Description:The activity of compound of the invention can be determined by a co-activator recruitment by TR-FRET (time-resolved fluorescence resonance energy tra...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2019
Entry Details
US Patent

TargetNuclear receptor ROR-gamma(Human)
Pfizer

US Patent
LigandChemical structure of BindingDB Monomer ID 189886BDBM189886(US9670201, 13 3-chloro-N-(3-(1-isobutyrylpiperidin...)
Affinity DataIC50: 5nMAssay Description:The activity of compound of the invention can be determined by a co-activator recruitment by TR-FRET (time-resolved fluorescence resonance energy tra...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2019
Entry Details
US Patent

TargetNuclear receptor ROR-gamma(Human)
Pfizer

US Patent
LigandChemical structure of BindingDB Monomer ID 189894BDBM189894(US9670201, 21 (R)-3-cyano-N-(1-methyl-4-(trifluoro...)
Affinity DataIC50: 5nMAssay Description:The activity of compound of the invention can be determined by a co-activator recruitment by TR-FRET (time-resolved fluorescence resonance energy tra...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2019
Entry Details
US Patent

TargetNuclear receptor ROR-gamma(Human)
Pfizer

US Patent
LigandChemical structure of BindingDB Monomer ID 190326BDBM190326(US9670201, 82 3-cyano-2-fluoro-N-(3-((3R,4R)-1-iso...)
Affinity DataIC50: 5.10nMAssay Description:The activity of compound of the invention can be determined by a co-activator recruitment by TR-FRET (time-resolved fluorescence resonance energy tra...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2019
Entry Details
US Patent

TargetNuclear receptor ROR-gamma(Human)
Pfizer

US Patent
LigandChemical structure of BindingDB Monomer ID 190320BDBM190320(US9670201, 77 3-cyano-N-(3-((1R,5S,8r)-3-isobutyry...)
Affinity DataIC50: 5.20nMAssay Description:The activity of compound of the invention can be determined by a co-activator recruitment by TR-FRET (time-resolved fluorescence resonance energy tra...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2019
Entry Details
US Patent

TargetNuclear receptor ROR-gamma(Human)
Pfizer

US Patent
LigandChemical structure of BindingDB Monomer ID 189893BDBM189893(US9670201, 20 3-cyano-N-(3-(1-(2-cyclohexylacetyl)...)
Affinity DataIC50: 5.20nMAssay Description:The activity of compound of the invention can be determined by a co-activator recruitment by TR-FRET (time-resolved fluorescence resonance energy tra...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2019
Entry Details
US Patent

TargetNuclear receptor ROR-gamma(Human)
Pfizer

US Patent
LigandChemical structure of BindingDB Monomer ID 189890BDBM189890(US9670201, 17 3-cyano-N-(1-methyl-4-(trifluorometh...)
Affinity DataIC50: 5.30nMAssay Description:The activity of compound of the invention can be determined by a co-activator recruitment by TR-FRET (time-resolved fluorescence resonance energy tra...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2019
Entry Details
US Patent

TargetNuclear receptor ROR-gamma(Human)
Pfizer

US Patent
LigandChemical structure of BindingDB Monomer ID 189881BDBM189881(US9670201, 9 3-cyano-4-fluoro-N-(3-(1-isobutyrylpi...)
Affinity DataIC50: 5.40nMAssay Description:The activity of compound of the invention can be determined by a co-activator recruitment by TR-FRET (time-resolved fluorescence resonance energy tra...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2019
Entry Details
US Patent

TargetNuclear receptor ROR-gamma(Human)
Pfizer

US Patent
LigandChemical structure of BindingDB Monomer ID 189880BDBM189880(US9670201, 8 3-cyano-N-(3-(1-isobutyrylpiperidin-4...)
Affinity DataIC50: 5.40nMAssay Description:The activity of compound of the invention can be determined by a co-activator recruitment by TR-FRET (time-resolved fluorescence resonance energy tra...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2019
Entry Details
US Patent

TargetNuclear receptor ROR-gamma(Human)
Pfizer

US Patent
LigandChemical structure of BindingDB Monomer ID 189906BDBM189906(US9670201, 31 (S)-3-cyano-4-methoxy-N-(1-methyl-4-...)
Affinity DataIC50: 5.60nMAssay Description:The activity of compound of the invention can be determined by a co-activator recruitment by TR-FRET (time-resolved fluorescence resonance energy tra...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2019
Entry Details
US Patent

TargetNuclear receptor ROR-gamma(Human)
Pfizer

US Patent
LigandChemical structure of BindingDB Monomer ID 189887BDBM189887(US9670201, 14 3-cyano-N-(3-(1-(2-cyclopentylacetyl...)
Affinity DataIC50: 5.60nMAssay Description:The activity of compound of the invention can be determined by a co-activator recruitment by TR-FRET (time-resolved fluorescence resonance energy tra...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2019
Entry Details
US Patent

TargetNuclear receptor ROR-gamma(Human)
Pfizer

US Patent
LigandChemical structure of BindingDB Monomer ID 190312BDBM190312(US9670201, 70 (R)-3-cyano-N-(3-(1-isobutyryl-2,2-d...)
Affinity DataIC50: 5.60nMAssay Description:The activity of compound of the invention can be determined by a co-activator recruitment by TR-FRET (time-resolved fluorescence resonance energy tra...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2019
Entry Details
US Patent

TargetNuclear receptor ROR-gamma(Human)
Pfizer

US Patent
LigandChemical structure of BindingDB Monomer ID 189938BDBM189938(US9670201, 56 (R)-3-cyano-N-(1,4-dimethyl-3-(1-(2,...)
Affinity DataIC50: 5.60nMAssay Description:The activity of compound of the invention can be determined by a co-activator recruitment by TR-FRET (time-resolved fluorescence resonance energy tra...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2019
Entry Details
US Patent

TargetNuclear receptor ROR-gamma(Human)
Pfizer

US Patent
LigandChemical structure of BindingDB Monomer ID 190304BDBM190304(US9670201, 65 (R)-3-cyano-N-(3-(1-(cyclopentanecar...)
Affinity DataIC50: 5.70nMAssay Description:The activity of compound of the invention can be determined by a co-activator recruitment by TR-FRET (time-resolved fluorescence resonance energy tra...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2019
Entry Details
US Patent

TargetNuclear receptor ROR-gamma(Human)
Pfizer

US Patent
LigandChemical structure of BindingDB Monomer ID 189910BDBM189910(US9670201, 34 3-cyano-N-(3-(1-(2,3-dihydro-1H-inde...)
Affinity DataIC50: 5.70nMAssay Description:The activity of compound of the invention can be determined by a co-activator recruitment by TR-FRET (time-resolved fluorescence resonance energy tra...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2019
Entry Details
US Patent

TargetNuclear receptor ROR-gamma(Human)
Pfizer

US Patent
LigandChemical structure of BindingDB Monomer ID 189878BDBM189878(US9670201, 6 3-cyano-N-(3-(1-isobutyrylpiperidin-4...)
Affinity DataIC50: 5.70nMAssay Description:The activity of compound of the invention can be determined by a co-activator recruitment by TR-FRET (time-resolved fluorescence resonance energy tra...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2019
Entry Details
US Patent

TargetNuclear receptor ROR-gamma(Human)
Pfizer

US Patent
LigandChemical structure of BindingDB Monomer ID 189899BDBM189899(US9670201, 25 Rac-3-cyano-N-(3-(1-(2-cyclopropylpr...)
Affinity DataIC50: 5.80nMAssay Description:The activity of compound of the invention can be determined by a co-activator recruitment by TR-FRET (time-resolved fluorescence resonance energy tra...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2019
Entry Details
US Patent

TargetNuclear receptor ROR-gamma(Human)
Pfizer

US Patent
LigandChemical structure of BindingDB Monomer ID 189898BDBM189898(US9670201, 24 3-cyano-N-(3-(1-(2-cyclopropylacetyl...)
Affinity DataIC50: 5.80nMAssay Description:The activity of compound of the invention can be determined by a co-activator recruitment by TR-FRET (time-resolved fluorescence resonance energy tra...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2019
Entry Details
US Patent

TargetNuclear receptor ROR-gamma(Human)
Pfizer

US Patent
LigandChemical structure of BindingDB Monomer ID 189931BDBM189931(US9670201, 49 3-cyano-N-(3-(1-((1R,2S)-2-isopropyl...)
Affinity DataIC50: 6.20nMAssay Description:The activity of compound of the invention can be determined by a co-activator recruitment by TR-FRET (time-resolved fluorescence resonance energy tra...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2019
Entry Details
US Patent

TargetNuclear receptor ROR-gamma(Human)
Pfizer

US Patent
LigandChemical structure of BindingDB Monomer ID 190317BDBM190317(US9670201, 74 (R)-3-cyano-N-(3-(1-(2-cyclopentylac...)
Affinity DataIC50: 6.20nMAssay Description:The activity of compound of the invention can be determined by a co-activator recruitment by TR-FRET (time-resolved fluorescence resonance energy tra...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2019
Entry Details
US Patent

TargetNuclear receptor ROR-gamma(Human)
Pfizer

US Patent
LigandChemical structure of BindingDB Monomer ID 189902BDBM189902(US9670201, 27 Rac-3-cyano-N-(1-methyl-3-(1-((1R*,2...)
Affinity DataIC50: 6.40nMAssay Description:The activity of compound of the invention can be determined by a co-activator recruitment by TR-FRET (time-resolved fluorescence resonance energy tra...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2019
Entry Details
US Patent

TargetNuclear receptor ROR-gamma(Human)
Pfizer

US Patent
LigandChemical structure of BindingDB Monomer ID 189901BDBM189901(US9670201, 26 Rac-3-cyano-N-(1-methyl-3-(1-((1S*,2...)
Affinity DataIC50: 6.60nMAssay Description:The activity of compound of the invention can be determined by a co-activator recruitment by TR-FRET (time-resolved fluorescence resonance energy tra...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2019
Entry Details
US Patent

TargetNuclear receptor ROR-gamma(Human)
Pfizer

US Patent
LigandChemical structure of BindingDB Monomer ID 189933BDBM189933(US9670201, 51 (R)-3-cyano-N-(3-(1-(2-cyclopentylpr...)
Affinity DataIC50: 6.90nMAssay Description:The activity of compound of the invention can be determined by a co-activator recruitment by TR-FRET (time-resolved fluorescence resonance energy tra...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2019
Entry Details
US Patent

TargetNuclear receptor ROR-gamma(Human)
Pfizer

US Patent
LigandChemical structure of BindingDB Monomer ID 189903BDBM189903(US9670201, 28 (R)-3-cyano-N-(1-methyl-3-(1-(tetrah...)
Affinity DataIC50: 7.10nMAssay Description:The activity of compound of the invention can be determined by a co-activator recruitment by TR-FRET (time-resolved fluorescence resonance energy tra...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2019
Entry Details
US Patent

TargetNuclear receptor ROR-gamma(Human)
Pfizer

US Patent
LigandChemical structure of BindingDB Monomer ID 189872BDBM189872(US9670201, 1 3-cyano-N-(3-(1-(cyclopentanecarbonyl...)
Affinity DataIC50: 7.10nMAssay Description:The activity of compound of the invention can be determined by a co-activator recruitment by TR-FRET (time-resolved fluorescence resonance energy tra...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2019
Entry Details
US Patent

TargetNuclear receptor ROR-gamma(Human)
Pfizer

US Patent
LigandChemical structure of BindingDB Monomer ID 368614BDBM368614(N-(3-(1-((1R,2S,4S)-bicyclo[2.2.1]heptane-2- carbo...)
Affinity DataIC50: 7.20nMAssay Description:The activity of compound of the invention can be determined by a co-activator recruitment by TR-FRET (time-resolved fluorescence resonance energy tra...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2019
Entry Details
US Patent

TargetNuclear receptor ROR-gamma(Human)
Pfizer

US Patent
LigandChemical structure of BindingDB Monomer ID 190318BDBM190318(US9670201, 75 (R)-3-cyano-N-(3-(1-(2-cyclohexylace...)
Affinity DataIC50: 7.30nMAssay Description:The activity of compound of the invention can be determined by a co-activator recruitment by TR-FRET (time-resolved fluorescence resonance energy tra...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2019
Entry Details
US Patent

TargetNuclear receptor ROR-gamma(Human)
Pfizer

US Patent
LigandChemical structure of BindingDB Monomer ID 190307BDBM190307(US9670201, 66 (R)-3-cyano-N-(3-(1-isobutyryl-2,2-d...)
Affinity DataIC50: 7.40nMAssay Description:The activity of compound of the invention can be determined by a co-activator recruitment by TR-FRET (time-resolved fluorescence resonance energy tra...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2019
Entry Details
US Patent

TargetNuclear receptor ROR-gamma(Human)
Pfizer

US Patent
LigandChemical structure of BindingDB Monomer ID 190319BDBM190319(US9670201, 76 (R)-3-cyano-N-(3-(1-(2-cyclobutylace...)
Affinity DataIC50: 7.5nMAssay Description:The activity of compound of the invention can be determined by a co-activator recruitment by TR-FRET (time-resolved fluorescence resonance energy tra...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2019
Entry Details
US Patent

TargetNuclear receptor ROR-gamma(Human)
Pfizer

US Patent
LigandChemical structure of BindingDB Monomer ID 189932BDBM189932(US9670201, 50 (R)-N-(3-(1-(2-(bicyclo[1.1.1]pentan...)
Affinity DataIC50: 7.5nMAssay Description:The activity of compound of the invention can be determined by a co-activator recruitment by TR-FRET (time-resolved fluorescence resonance energy tra...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2019
Entry Details
US Patent

TargetNuclear receptor ROR-gamma(Human)
Pfizer

US Patent
LigandChemical structure of BindingDB Monomer ID 189919BDBM189919(US9670201, 42 (R)-3-chloro-N-(1,4-dimethyl-3-(1-(2...)
Affinity DataIC50: 7.60nMAssay Description:The activity of compound of the invention can be determined by a co-activator recruitment by TR-FRET (time-resolved fluorescence resonance energy tra...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2019
Entry Details
US Patent

TargetNuclear receptor ROR-gamma(Human)
Pfizer

US Patent
LigandChemical structure of BindingDB Monomer ID 189917BDBM189917(US9670201, 40 (R)-5-cyano-N-(1,4-dimethyl-3-(1-(2,...)
Affinity DataIC50: 7.60nMAssay Description:The activity of compound of the invention can be determined by a co-activator recruitment by TR-FRET (time-resolved fluorescence resonance energy tra...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2019
Entry Details
US Patent

TargetNuclear receptor ROR-gamma(Human)
Pfizer

US Patent
LigandChemical structure of BindingDB Monomer ID 189915BDBM189915(US9670201, 38 (R)-3-cyano-N-(1,4-dimethyl-3-(1-(2,...)
Affinity DataIC50: 7.70nMAssay Description:The activity of compound of the invention can be determined by a co-activator recruitment by TR-FRET (time-resolved fluorescence resonance energy tra...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2019
Entry Details
US Patent

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