Compile Data Set for Download or QSAR
Report error Found 48 Enz. Inhib. hit(s) with all data for entry = 2541
TargetPRKC apoptosis WT1 regulator protein(Human)
Universite De Montreal

US Patent
LigandChemical structure of BindingDB Monomer ID 370580BDBM370580(US10238638, Example 9)
Affinity DataIC50: 330nMAssay Description:The FLIPR assay is an exemplary in vitro assay for measuring the activity of the PAR4 antagonists of the present invention. In this assay, intracellu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2019
Entry Details
US Patent

TargetPRKC apoptosis WT1 regulator protein(Human)
Universite De Montreal

US Patent
LigandChemical structure of BindingDB Monomer ID 370593BDBM370593(US10238638, Example 22)
Affinity DataIC50: 760nMAssay Description:The FLIPR assay is an exemplary in vitro assay for measuring the activity of the PAR4 antagonists of the present invention. In this assay, intracellu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2019
Entry Details
US Patent

TargetPRKC apoptosis WT1 regulator protein(Human)
Universite De Montreal

US Patent
LigandChemical structure of BindingDB Monomer ID 370592BDBM370592(US10238638, Example 21)
Affinity DataIC50: 920nMAssay Description:The FLIPR assay is an exemplary in vitro assay for measuring the activity of the PAR4 antagonists of the present invention. In this assay, intracellu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2019
Entry Details
US Patent

TargetPRKC apoptosis WT1 regulator protein(Human)
Universite De Montreal

US Patent
LigandChemical structure of BindingDB Monomer ID 370620BDBM370620(US10238638, Example 67)
Affinity DataIC50: 930nMAssay Description:The FLIPR assay is an exemplary in vitro assay for measuring the activity of the PAR4 antagonists of the present invention. In this assay, intracellu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2019
Entry Details
US Patent

TargetPRKC apoptosis WT1 regulator protein(Human)
Universite De Montreal

US Patent
LigandChemical structure of BindingDB Monomer ID 370581BDBM370581(US10238638, Example 10)
Affinity DataIC50: 980nMAssay Description:The FLIPR assay is an exemplary in vitro assay for measuring the activity of the PAR4 antagonists of the present invention. In this assay, intracellu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2019
Entry Details
US Patent

TargetPRKC apoptosis WT1 regulator protein(Human)
Universite De Montreal

US Patent
LigandChemical structure of BindingDB Monomer ID 370497BDBM370497(US10238638, Example 5)
Affinity DataIC50: 1.10E+3nMAssay Description:The FLIPR assay is an exemplary in vitro assay for measuring the activity of the PAR4 antagonists of the present invention. In this assay, intracellu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2019
Entry Details
US Patent

TargetPRKC apoptosis WT1 regulator protein(Human)
Universite De Montreal

US Patent
LigandChemical structure of BindingDB Monomer ID 370613BDBM370613(US10238638, Example 42)
Affinity DataIC50: 1.10E+3nMAssay Description:The FLIPR assay is an exemplary in vitro assay for measuring the activity of the PAR4 antagonists of the present invention. In this assay, intracellu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2019
Entry Details
US Patent

TargetPRKC apoptosis WT1 regulator protein(Human)
Universite De Montreal

US Patent
LigandChemical structure of BindingDB Monomer ID 370591BDBM370591(US10238638, Example 20)
Affinity DataIC50: 1.20E+3nMAssay Description:The FLIPR assay is an exemplary in vitro assay for measuring the activity of the PAR4 antagonists of the present invention. In this assay, intracellu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2019
Entry Details
US Patent

TargetPRKC apoptosis WT1 regulator protein(Human)
Universite De Montreal

US Patent
LigandChemical structure of BindingDB Monomer ID 370606BDBM370606(US10238638, Example 35)
Affinity DataIC50: 1.20E+3nMAssay Description:The FLIPR assay is an exemplary in vitro assay for measuring the activity of the PAR4 antagonists of the present invention. In this assay, intracellu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2019
Entry Details
US Patent

TargetPRKC apoptosis WT1 regulator protein(Human)
Universite De Montreal

US Patent
LigandChemical structure of BindingDB Monomer ID 370598BDBM370598(US10238638, Example 27)
Affinity DataIC50: 1.20E+3nMAssay Description:The FLIPR assay is an exemplary in vitro assay for measuring the activity of the PAR4 antagonists of the present invention. In this assay, intracellu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2019
Entry Details
US Patent

TargetPRKC apoptosis WT1 regulator protein(Human)
Universite De Montreal

US Patent
LigandChemical structure of BindingDB Monomer ID 370607BDBM370607(US10238638, Example 36)
Affinity DataIC50: 1.30E+3nMAssay Description:The FLIPR assay is an exemplary in vitro assay for measuring the activity of the PAR4 antagonists of the present invention. In this assay, intracellu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2019
Entry Details
US Patent

TargetPRKC apoptosis WT1 regulator protein(Human)
Universite De Montreal

US Patent
LigandChemical structure of BindingDB Monomer ID 370605BDBM370605(US10238638, Example 34)
Affinity DataIC50: 1.30E+3nMAssay Description:The FLIPR assay is an exemplary in vitro assay for measuring the activity of the PAR4 antagonists of the present invention. In this assay, intracellu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2019
Entry Details
US Patent

TargetPRKC apoptosis WT1 regulator protein(Human)
Universite De Montreal

US Patent
LigandChemical structure of BindingDB Monomer ID 370603BDBM370603(US10238638, Example 32)
Affinity DataIC50: 1.40E+3nMAssay Description:The FLIPR assay is an exemplary in vitro assay for measuring the activity of the PAR4 antagonists of the present invention. In this assay, intracellu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2019
Entry Details
US Patent

TargetPRKC apoptosis WT1 regulator protein(Human)
Universite De Montreal

US Patent
LigandChemical structure of BindingDB Monomer ID 370582BDBM370582(US10238638, Example 11)
Affinity DataIC50: 1.40E+3nMAssay Description:The FLIPR assay is an exemplary in vitro assay for measuring the activity of the PAR4 antagonists of the present invention. In this assay, intracellu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2019
Entry Details
US Patent

TargetPRKC apoptosis WT1 regulator protein(Human)
Universite De Montreal

US Patent
LigandChemical structure of BindingDB Monomer ID 370608BDBM370608(US10238638, Example 38 | (S)-(3-Hydroxypiperidin-1...)
Affinity DataIC50: 1.60E+3nMAssay Description:The FLIPR assay is an exemplary in vitro assay for measuring the activity of the PAR4 antagonists of the present invention. In this assay, intracellu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2019
Entry Details
US Patent

TargetPRKC apoptosis WT1 regulator protein(Human)
Universite De Montreal

US Patent
LigandChemical structure of BindingDB Monomer ID 370610BDBM370610(US10238638, Example 40)
Affinity DataIC50: 1.60E+3nMAssay Description:The FLIPR assay is an exemplary in vitro assay for measuring the activity of the PAR4 antagonists of the present invention. In this assay, intracellu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2019
Entry Details
US Patent

TargetPRKC apoptosis WT1 regulator protein(Human)
Universite De Montreal

US Patent
LigandChemical structure of BindingDB Monomer ID 370612BDBM370612(US10238638, Example 41)
Affinity DataIC50: 1.70E+3nMAssay Description:The FLIPR assay is an exemplary in vitro assay for measuring the activity of the PAR4 antagonists of the present invention. In this assay, intracellu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2019
Entry Details
US Patent

TargetPRKC apoptosis WT1 regulator protein(Human)
Universite De Montreal

US Patent
LigandChemical structure of BindingDB Monomer ID 370579BDBM370579(US10238638, Example 8)
Affinity DataIC50: 1.80E+3nMAssay Description:The FLIPR assay is an exemplary in vitro assay for measuring the activity of the PAR4 antagonists of the present invention. In this assay, intracellu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2019
Entry Details
US Patent

TargetPRKC apoptosis WT1 regulator protein(Human)
Universite De Montreal

US Patent
LigandChemical structure of BindingDB Monomer ID 370609BDBM370609(US10238638, Example 39)
Affinity DataIC50: 1.80E+3nMAssay Description:The FLIPR assay is an exemplary in vitro assay for measuring the activity of the PAR4 antagonists of the present invention. In this assay, intracellu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2019
Entry Details
US Patent

TargetPRKC apoptosis WT1 regulator protein(Human)
Universite De Montreal

US Patent
LigandChemical structure of BindingDB Monomer ID 370616BDBM370616(US10238638, Example 45 | 5-Methoxy-2-(6-methylimid...)
Affinity DataIC50: 1.80E+3nMAssay Description:The FLIPR assay is an exemplary in vitro assay for measuring the activity of the PAR4 antagonists of the present invention. In this assay, intracellu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2019
Entry Details
US Patent

TargetPRKC apoptosis WT1 regulator protein(Human)
Universite De Montreal

US Patent
LigandChemical structure of BindingDB Monomer ID 370602BDBM370602(US10238638, Example 31 | tert-Butyl 4-(4-(((2-(2-e...)
Affinity DataIC50: 2.00E+3nMAssay Description:The FLIPR assay is an exemplary in vitro assay for measuring the activity of the PAR4 antagonists of the present invention. In this assay, intracellu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2019
Entry Details
US Patent

TargetPRKC apoptosis WT1 regulator protein(Human)
Universite De Montreal

US Patent
LigandChemical structure of BindingDB Monomer ID 370432BDBM370432(US10238638, Example 1)
Affinity DataIC50: 2.40E+3nMAssay Description:The FLIPR assay is an exemplary in vitro assay for measuring the activity of the PAR4 antagonists of the present invention. In this assay, intracellu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2019
Entry Details
US Patent

TargetPRKC apoptosis WT1 regulator protein(Human)
Universite De Montreal

US Patent
LigandChemical structure of BindingDB Monomer ID 370617BDBM370617(US10238638, Example 46)
Affinity DataIC50: 2.50E+3nMAssay Description:The FLIPR assay is an exemplary in vitro assay for measuring the activity of the PAR4 antagonists of the present invention. In this assay, intracellu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2019
Entry Details
US Patent

TargetPRKC apoptosis WT1 regulator protein(Human)
Universite De Montreal

US Patent
LigandChemical structure of BindingDB Monomer ID 370588BDBM370588(US10238638, Example 17)
Affinity DataIC50: 2.60E+3nMAssay Description:The FLIPR assay is an exemplary in vitro assay for measuring the activity of the PAR4 antagonists of the present invention. In this assay, intracellu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2019
Entry Details
US Patent

TargetPRKC apoptosis WT1 regulator protein(Human)
Universite De Montreal

US Patent
LigandChemical structure of BindingDB Monomer ID 370596BDBM370596(US10238638, Example 25 | (S)-4-(4-(((2-(2-Cyclopro...)
Affinity DataIC50: 2.60E+3nMAssay Description:The FLIPR assay is an exemplary in vitro assay for measuring the activity of the PAR4 antagonists of the present invention. In this assay, intracellu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2019
Entry Details
US Patent

TargetPRKC apoptosis WT1 regulator protein(Human)
Universite De Montreal

US Patent
LigandChemical structure of BindingDB Monomer ID 370615BDBM370615(US10238638, Example 44 | 4-(4-(((5-Methoxy-2-(6-me...)
Affinity DataIC50: 2.60E+3nMAssay Description:The FLIPR assay is an exemplary in vitro assay for measuring the activity of the PAR4 antagonists of the present invention. In this assay, intracellu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2019
Entry Details
US Patent

TargetPRKC apoptosis WT1 regulator protein(Human)
Universite De Montreal

US Patent
LigandChemical structure of BindingDB Monomer ID 370604BDBM370604(US10238638, Example 33)
Affinity DataIC50: 3.60E+3nMAssay Description:The FLIPR assay is an exemplary in vitro assay for measuring the activity of the PAR4 antagonists of the present invention. In this assay, intracellu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2019
Entry Details
US Patent

TargetPRKC apoptosis WT1 regulator protein(Human)
Universite De Montreal

US Patent
LigandChemical structure of BindingDB Monomer ID 370450BDBM370450(US10238638, Example 3)
Affinity DataIC50: 3.60E+3nMAssay Description:The FLIPR assay is an exemplary in vitro assay for measuring the activity of the PAR4 antagonists of the present invention. In this assay, intracellu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2019
Entry Details
US Patent

TargetPRKC apoptosis WT1 regulator protein(Human)
Universite De Montreal

US Patent
LigandChemical structure of BindingDB Monomer ID 370586BDBM370586(US10238638, Example 15)
Affinity DataIC50: 3.70E+3nMAssay Description:The FLIPR assay is an exemplary in vitro assay for measuring the activity of the PAR4 antagonists of the present invention. In this assay, intracellu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2019
Entry Details
US Patent

TargetPRKC apoptosis WT1 regulator protein(Human)
Universite De Montreal

US Patent
LigandChemical structure of BindingDB Monomer ID 370599BDBM370599(US10238638, Example 28)
Affinity DataIC50: 3.70E+3nMAssay Description:The FLIPR assay is an exemplary in vitro assay for measuring the activity of the PAR4 antagonists of the present invention. In this assay, intracellu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2019
Entry Details
US Patent

TargetPRKC apoptosis WT1 regulator protein(Human)
Universite De Montreal

US Patent
LigandChemical structure of BindingDB Monomer ID 370498BDBM370498(US10238638, Example 6)
Affinity DataIC50: 3.80E+3nMAssay Description:The FLIPR assay is an exemplary in vitro assay for measuring the activity of the PAR4 antagonists of the present invention. In this assay, intracellu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2019
Entry Details
US Patent

TargetPRKC apoptosis WT1 regulator protein(Human)
Universite De Montreal

US Patent
LigandChemical structure of BindingDB Monomer ID 370496BDBM370496(US10238638, Example 4)
Affinity DataIC50: 4.20E+3nMAssay Description:The FLIPR assay is an exemplary in vitro assay for measuring the activity of the PAR4 antagonists of the present invention. In this assay, intracellu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2019
Entry Details
US Patent

TargetPRKC apoptosis WT1 regulator protein(Human)
Universite De Montreal

US Patent
LigandChemical structure of BindingDB Monomer ID 370589BDBM370589(US10238638, Example 18)
Affinity DataIC50: 5.10E+3nMAssay Description:The FLIPR assay is an exemplary in vitro assay for measuring the activity of the PAR4 antagonists of the present invention. In this assay, intracellu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2019
Entry Details
US Patent

TargetPRKC apoptosis WT1 regulator protein(Human)
Universite De Montreal

US Patent
LigandChemical structure of BindingDB Monomer ID 370618BDBM370618(US10238638, Example 47 | (S)-4-(4-(((5-Methoxy-2-(...)
Affinity DataIC50: 6.40E+3nMAssay Description:The FLIPR assay is an exemplary in vitro assay for measuring the activity of the PAR4 antagonists of the present invention. In this assay, intracellu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2019
Entry Details
US Patent

TargetPRKC apoptosis WT1 regulator protein(Human)
Universite De Montreal

US Patent
LigandChemical structure of BindingDB Monomer ID 370597BDBM370597(US10238638, Example 26)
Affinity DataIC50: 9.10E+3nMAssay Description:The FLIPR assay is an exemplary in vitro assay for measuring the activity of the PAR4 antagonists of the present invention. In this assay, intracellu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2019
Entry Details
US Patent

TargetPRKC apoptosis WT1 regulator protein(Human)
Universite De Montreal

US Patent
LigandChemical structure of BindingDB Monomer ID 370619BDBM370619(US10238638, Example 48)
Affinity DataIC50: 9.90E+3nMAssay Description:The FLIPR assay is an exemplary in vitro assay for measuring the activity of the PAR4 antagonists of the present invention. In this assay, intracellu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2019
Entry Details
US Patent

TargetPRKC apoptosis WT1 regulator protein(Human)
Universite De Montreal

US Patent
LigandChemical structure of BindingDB Monomer ID 370587BDBM370587(US10238638, Example 16)
Affinity DataIC50: 1.50E+4nMAssay Description:The FLIPR assay is an exemplary in vitro assay for measuring the activity of the PAR4 antagonists of the present invention. In this assay, intracellu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2019
Entry Details
US Patent

TargetPRKC apoptosis WT1 regulator protein(Human)
Universite De Montreal

US Patent
LigandChemical structure of BindingDB Monomer ID 370499BDBM370499(US10238638, Example 7)
Affinity DataIC50: 3.00E+4nMAssay Description:The FLIPR assay is an exemplary in vitro assay for measuring the activity of the PAR4 antagonists of the present invention. In this assay, intracellu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2019
Entry Details
US Patent

TargetPRKC apoptosis WT1 regulator protein(Human)
Universite De Montreal

US Patent
LigandChemical structure of BindingDB Monomer ID 370449BDBM370449(US10238638, Example 2)
Affinity DataIC50: 4.50E+4nMAssay Description:The FLIPR assay is an exemplary in vitro assay for measuring the activity of the PAR4 antagonists of the present invention. In this assay, intracellu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2019
Entry Details
US Patent

TargetPRKC apoptosis WT1 regulator protein(Human)
Universite De Montreal

US Patent
LigandChemical structure of BindingDB Monomer ID 370600BDBM370600(US10238638, Example 29)
Affinity DataIC50: 8.00E+4nMAssay Description:The FLIPR assay is an exemplary in vitro assay for measuring the activity of the PAR4 antagonists of the present invention. In this assay, intracellu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2019
Entry Details
US Patent

TargetPRKC apoptosis WT1 regulator protein(Human)
Universite De Montreal

US Patent
LigandChemical structure of BindingDB Monomer ID 370590BDBM370590(US10238638, Example 19)
Affinity DataIC50: 8.10E+4nMAssay Description:The FLIPR assay is an exemplary in vitro assay for measuring the activity of the PAR4 antagonists of the present invention. In this assay, intracellu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2019
Entry Details
US Patent

TargetPRKC apoptosis WT1 regulator protein(Human)
Universite De Montreal

US Patent
LigandChemical structure of BindingDB Monomer ID 370585BDBM370585(US10238638, Example 14)
Affinity DataIC50: 8.70E+4nMAssay Description:The FLIPR assay is an exemplary in vitro assay for measuring the activity of the PAR4 antagonists of the present invention. In this assay, intracellu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2019
Entry Details
US Patent

TargetPRKC apoptosis WT1 regulator protein(Human)
Universite De Montreal

US Patent
LigandChemical structure of BindingDB Monomer ID 370601BDBM370601(US10238638, Example 30)
Affinity DataIC50: 3.20E+5nMAssay Description:The FLIPR assay is an exemplary in vitro assay for measuring the activity of the PAR4 antagonists of the present invention. In this assay, intracellu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2019
Entry Details
US Patent

TargetPRKC apoptosis WT1 regulator protein(Human)
Universite De Montreal

US Patent
LigandChemical structure of BindingDB Monomer ID 370595BDBM370595(US10238638, Example 24 | tert-Butyl 4-(4-(((2-(2-c...)
Affinity DataIC50: 3.80E+5nMAssay Description:The FLIPR assay is an exemplary in vitro assay for measuring the activity of the PAR4 antagonists of the present invention. In this assay, intracellu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2019
Entry Details
US Patent

TargetPRKC apoptosis WT1 regulator protein(Human)
Universite De Montreal

US Patent
LigandChemical structure of BindingDB Monomer ID 370614BDBM370614(US10238638, Example 43)
Affinity DataIC50: 5.00E+5nMAssay Description:The FLIPR assay is an exemplary in vitro assay for measuring the activity of the PAR4 antagonists of the present invention. In this assay, intracellu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2019
Entry Details
US Patent

TargetPRKC apoptosis WT1 regulator protein(Human)
Universite De Montreal

US Patent
LigandChemical structure of BindingDB Monomer ID 370584BDBM370584(US10238638, Example 13 | tert-Butyl 4-(4-(((2-(2-(...)
Affinity DataIC50: 8.00E+5nMAssay Description:The FLIPR assay is an exemplary in vitro assay for measuring the activity of the PAR4 antagonists of the present invention. In this assay, intracellu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2019
Entry Details
US Patent

TargetPRKC apoptosis WT1 regulator protein(Human)
Universite De Montreal

US Patent
LigandChemical structure of BindingDB Monomer ID 370594BDBM370594(US10238638, Example 23)
Affinity DataIC50: 8.30E+5nMAssay Description:The FLIPR assay is an exemplary in vitro assay for measuring the activity of the PAR4 antagonists of the present invention. In this assay, intracellu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2019
Entry Details
US Patent

TargetPRKC apoptosis WT1 regulator protein(Human)
Universite De Montreal

US Patent
LigandChemical structure of BindingDB Monomer ID 370583BDBM370583(US10238638, Example 12 | 7-(Benzyloxy)-2-(2-(1,1-d...)
Affinity DataIC50: 3.20E+6nMAssay Description:The FLIPR assay is an exemplary in vitro assay for measuring the activity of the PAR4 antagonists of the present invention. In this assay, intracellu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2019
Entry Details
US Patent