Compile Data Set for Download or QSAR
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Found 18 Enz. Inhib. hit(s) with all data for entry = 3387
TargetTyrosine-protein kinase JAK1(Homo sapiens (Human))
Eli Lilly

US Patent
LigandPNGBDBM398506((2R)-1,1,1-Trifluoro-3-({cis-4-[(1-methyl-4-{[1-(p...)
Affinity DataIC50:  1.49nMAssay Description:The JAK LanthaScreen Kinase Assay (Invitrogen) is used to determine the ability of test compounds to inhibit JAK1, JAK2, and JAK3 kinase activity. Th...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase JAK1(Homo sapiens (Human))
Eli Lilly

US Patent
LigandPNGBDBM398504((2R)-1,1,1-Trifluoro-3-[(cis-1-methyl-4-{[1-methyl...)
Affinity DataIC50:  1.91nMAssay Description:The JAK LanthaScreen Kinase Assay (Invitrogen) is used to determine the ability of test compounds to inhibit JAK1, JAK2, and JAK3 kinase activity. Th...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase JAK1(Homo sapiens (Human))
Eli Lilly

US Patent
LigandPNGBDBM398501((2R)-1,1,1-Trifluoro-3-({cis-4-[(4-{[1-(3-methoxyp...)
Affinity DataIC50:  3.25nMAssay Description:The JAK LanthaScreen Kinase Assay (Invitrogen) is used to determine the ability of test compounds to inhibit JAK1, JAK2, and JAK3 kinase activity. Th...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase JAK1(Homo sapiens (Human))
Eli Lilly

US Patent
LigandPNGBDBM398502((2R)-1,1,1-Trifluoro-3-{[cis-4-({4-[(5-methoxy-1-m...)
Affinity DataIC50:  5.25nMAssay Description:The JAK LanthaScreen Kinase Assay (Invitrogen) is used to determine the ability of test compounds to inhibit JAK1, JAK2, and JAK3 kinase activity. Th...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase JAK1(Homo sapiens (Human))
Eli Lilly

US Patent
LigandPNGBDBM398505((2R)-3-{[cis-4-({4-[(1,5-Dimethyl-1H-pyrazol-3-yl)...)
Affinity DataIC50:  5.35nMAssay Description:The JAK LanthaScreen Kinase Assay (Invitrogen) is used to determine the ability of test compounds to inhibit JAK1, JAK2, and JAK3 kinase activity. Th...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase JAK1(Homo sapiens (Human))
Eli Lilly

US Patent
LigandPNGBDBM398503((2R)-3-{[(cis-4-({4-[(Ethyl-5-methyl-1H-pyrazol-3-...)
Affinity DataIC50:  5.43nMAssay Description:The JAK LanthaScreen Kinase Assay (Invitrogen) is used to determine the ability of test compounds to inhibit JAK1, JAK2, and JAK3 kinase activity. Th...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
Eli Lilly

US Patent
LigandPNGBDBM398506((2R)-1,1,1-Trifluoro-3-({cis-4-[(1-methyl-4-{[1-(p...)
Affinity DataIC50:  220nMAssay Description:The JAK LanthaScreen Kinase Assay (Invitrogen) is used to determine the ability of test compounds to inhibit JAK1, JAK2, and JAK3 kinase activity. Th...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
Eli Lilly

US Patent
LigandPNGBDBM398504((2R)-1,1,1-Trifluoro-3-[(cis-1-methyl-4-{[1-methyl...)
Affinity DataIC50:  239nMAssay Description:The JAK LanthaScreen Kinase Assay (Invitrogen) is used to determine the ability of test compounds to inhibit JAK1, JAK2, and JAK3 kinase activity. Th...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase JAK3(Homo sapiens (Human))
Eli Lilly

US Patent
LigandPNGBDBM398506((2R)-1,1,1-Trifluoro-3-({cis-4-[(1-methyl-4-{[1-(p...)
Affinity DataIC50:  660nMAssay Description:The JAK LanthaScreen Kinase Assay (Invitrogen) is used to determine the ability of test compounds to inhibit JAK1, JAK2, and JAK3 kinase activity. Th...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
Eli Lilly

US Patent
LigandPNGBDBM398505((2R)-3-{[cis-4-({4-[(1,5-Dimethyl-1H-pyrazol-3-yl)...)
Affinity DataIC50:  767nMAssay Description:The JAK LanthaScreen Kinase Assay (Invitrogen) is used to determine the ability of test compounds to inhibit JAK1, JAK2, and JAK3 kinase activity. Th...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
Eli Lilly

US Patent
LigandPNGBDBM398502((2R)-1,1,1-Trifluoro-3-{[cis-4-({4-[(5-methoxy-1-m...)
Affinity DataIC50:  768nMAssay Description:The JAK LanthaScreen Kinase Assay (Invitrogen) is used to determine the ability of test compounds to inhibit JAK1, JAK2, and JAK3 kinase activity. Th...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
Eli Lilly

US Patent
LigandPNGBDBM398503((2R)-3-{[(cis-4-({4-[(Ethyl-5-methyl-1H-pyrazol-3-...)
Affinity DataIC50:  901nMAssay Description:The JAK LanthaScreen Kinase Assay (Invitrogen) is used to determine the ability of test compounds to inhibit JAK1, JAK2, and JAK3 kinase activity. Th...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase JAK3(Homo sapiens (Human))
Eli Lilly

US Patent
LigandPNGBDBM398504((2R)-1,1,1-Trifluoro-3-[(cis-1-methyl-4-{[1-methyl...)
Affinity DataIC50:  1.17E+3nMAssay Description:The JAK LanthaScreen Kinase Assay (Invitrogen) is used to determine the ability of test compounds to inhibit JAK1, JAK2, and JAK3 kinase activity. Th...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
Eli Lilly

US Patent
LigandPNGBDBM398501((2R)-1,1,1-Trifluoro-3-({cis-4-[(4-{[1-(3-methoxyp...)
Affinity DataIC50:  1.20E+3nMAssay Description:The JAK LanthaScreen Kinase Assay (Invitrogen) is used to determine the ability of test compounds to inhibit JAK1, JAK2, and JAK3 kinase activity. Th...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase JAK3(Homo sapiens (Human))
Eli Lilly

US Patent
LigandPNGBDBM398505((2R)-3-{[cis-4-({4-[(1,5-Dimethyl-1H-pyrazol-3-yl)...)
Affinity DataIC50:  2.14E+3nMAssay Description:The JAK LanthaScreen Kinase Assay (Invitrogen) is used to determine the ability of test compounds to inhibit JAK1, JAK2, and JAK3 kinase activity. Th...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase JAK3(Homo sapiens (Human))
Eli Lilly

US Patent
LigandPNGBDBM398502((2R)-1,1,1-Trifluoro-3-{[cis-4-({4-[(5-methoxy-1-m...)
Affinity DataIC50:  2.54E+3nMAssay Description:The JAK LanthaScreen Kinase Assay (Invitrogen) is used to determine the ability of test compounds to inhibit JAK1, JAK2, and JAK3 kinase activity. Th...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase JAK3(Homo sapiens (Human))
Eli Lilly

US Patent
LigandPNGBDBM398501((2R)-1,1,1-Trifluoro-3-({cis-4-[(4-{[1-(3-methoxyp...)
Affinity DataIC50:  3.72E+3nMAssay Description:The JAK LanthaScreen Kinase Assay (Invitrogen) is used to determine the ability of test compounds to inhibit JAK1, JAK2, and JAK3 kinase activity. Th...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase JAK3(Homo sapiens (Human))
Eli Lilly

US Patent
LigandPNGBDBM398503((2R)-3-{[(cis-4-({4-[(Ethyl-5-methyl-1H-pyrazol-3-...)
Affinity DataIC50:  6.16E+3nMAssay Description:The JAK LanthaScreen Kinase Assay (Invitrogen) is used to determine the ability of test compounds to inhibit JAK1, JAK2, and JAK3 kinase activity. Th...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent