Compile Data Set for Download or QSAR
Report error Found 15 Enz. Inhib. hit(s) with all data for entry = 3388
TargetAlpha-2C adrenergic receptor(Human)
Bayer Pharma Aktiengesellschaft

US Patent
LigandChemical structure of BindingDB Monomer ID 398510BDBM398510(US10323020, Example 4 | (rac)-{2-[(1-Methoxybutan-...)
Affinity DataIC50: 5nMAssay Description:Antagonism against the adrenoreceptor α1A was tested using a recombinant human α1A receptor CHO cell line which additionally also recombina...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/10/2020
Entry Details
US Patent

TargetAlpha-2C adrenergic receptor(Human)
Bayer Pharma Aktiengesellschaft

US Patent
LigandChemical structure of BindingDB Monomer ID 398515BDBM398515(US10323020, Example 9 | [4-(7-Fluoro-3,4-dihydrois...)
Affinity DataIC50: 16nMAssay Description:Antagonism against the adrenoreceptor α1A was tested using a recombinant human α1A receptor CHO cell line which additionally also recombina...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/10/2020
Entry Details
US Patent

TargetAlpha-2C adrenergic receptor(Human)
Bayer Pharma Aktiengesellschaft

US Patent
LigandChemical structure of BindingDB Monomer ID 398511BDBM398511(US10323020, Example 5 | (rac)-{2-[(1-Methoxybutan-...)
Affinity DataIC50: 20nMAssay Description:Antagonism against the adrenoreceptor α1A was tested using a recombinant human α1A receptor CHO cell line which additionally also recombina...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/10/2020
Entry Details
US Patent

TargetAlpha-2C adrenergic receptor(Human)
Bayer Pharma Aktiengesellschaft

US Patent
LigandChemical structure of BindingDB Monomer ID 398514BDBM398514(US10323020, Example 8 | [4-(3,4-Dihydroisoquinolin...)
Affinity DataIC50: 23nMAssay Description:Antagonism against the adrenoreceptor α1A was tested using a recombinant human α1A receptor CHO cell line which additionally also recombina...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/10/2020
Entry Details
US Patent

TargetAlpha-2C adrenergic receptor(Human)
Bayer Pharma Aktiengesellschaft

US Patent
LigandChemical structure of BindingDB Monomer ID 398508BDBM398508(US10323020, Example 2 | US10323020, Example 3 | (r...)
Affinity DataIC50: 24nMAssay Description:Antagonism against the adrenoreceptor α1A was tested using a recombinant human α1A receptor CHO cell line which additionally also recombina...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/10/2020
Entry Details
US Patent

TargetAlpha-2C adrenergic receptor(Human)
Bayer Pharma Aktiengesellschaft

US Patent
LigandChemical structure of BindingDB Monomer ID 398519BDBM398519(US10323020, Example 13 | US10323020, Example 14 | ...)
Affinity DataIC50: 24nMAssay Description:Antagonism against the adrenoreceptor α1A was tested using a recombinant human α1A receptor CHO cell line which additionally also recombina...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/10/2020
Entry Details
US Patent

TargetAlpha-2C adrenergic receptor(Human)
Bayer Pharma Aktiengesellschaft

US Patent
LigandChemical structure of BindingDB Monomer ID 398518BDBM398518(US10323020, Example 12 | [4-(3,4-Dihydroisoquinoli...)
Affinity DataIC50: 26nMAssay Description:Antagonism against the adrenoreceptor α1A was tested using a recombinant human α1A receptor CHO cell line which additionally also recombina...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/10/2020
Entry Details
US Patent

TargetAlpha-2C adrenergic receptor(Human)
Bayer Pharma Aktiengesellschaft

US Patent
LigandChemical structure of BindingDB Monomer ID 398508BDBM398508(US10323020, Example 2 | US10323020, Example 3 | (r...)
Affinity DataIC50: 26nMAssay Description:Antagonism against the adrenoreceptor α1A was tested using a recombinant human α1A receptor CHO cell line which additionally also recombina...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/10/2020
Entry Details
US Patent

TargetAlpha-2C adrenergic receptor(Human)
Bayer Pharma Aktiengesellschaft

US Patent
LigandChemical structure of BindingDB Monomer ID 398516BDBM398516(US10323020, Example 10 | [4-(6-Methoxy-3,4-dihydro...)
Affinity DataIC50: 30nMAssay Description:Antagonism against the adrenoreceptor α1A was tested using a recombinant human α1A receptor CHO cell line which additionally also recombina...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/10/2020
Entry Details
US Patent

TargetAlpha-2C adrenergic receptor(Human)
Bayer Pharma Aktiengesellschaft

US Patent
LigandChemical structure of BindingDB Monomer ID 398512BDBM398512(US10323020, Example 6 | (rac)-[4-(3,4-Dihydroisoqu...)
Affinity DataIC50: 31nMAssay Description:Antagonism against the adrenoreceptor α1A was tested using a recombinant human α1A receptor CHO cell line which additionally also recombina...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/10/2020
Entry Details
US Patent

TargetAlpha-2C adrenergic receptor(Human)
Bayer Pharma Aktiengesellschaft

US Patent
LigandChemical structure of BindingDB Monomer ID 398519BDBM398519(US10323020, Example 13 | US10323020, Example 14 | ...)
Affinity DataIC50: 47nMAssay Description:Antagonism against the adrenoreceptor α1A was tested using a recombinant human α1A receptor CHO cell line which additionally also recombina...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/10/2020
Entry Details
US Patent

TargetAlpha-2C adrenergic receptor(Human)
Bayer Pharma Aktiengesellschaft

US Patent
LigandChemical structure of BindingDB Monomer ID 398513BDBM398513(US10323020, Example 7 | (rac)-[4-(3,4-Dihydroisoqu...)
Affinity DataIC50: 68nMAssay Description:Antagonism against the adrenoreceptor α1A was tested using a recombinant human α1A receptor CHO cell line which additionally also recombina...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/10/2020
Entry Details
US Patent

TargetAlpha-2C adrenergic receptor(Human)
Bayer Pharma Aktiengesellschaft

US Patent
LigandChemical structure of BindingDB Monomer ID 398521BDBM398521(US10323020, Example 15 | [4-(3,4-Dihydroisoquinoli...)
Affinity DataIC50: 68nMAssay Description:Antagonism against the adrenoreceptor α1A was tested using a recombinant human α1A receptor CHO cell line which additionally also recombina...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/10/2020
Entry Details
US Patent

TargetAlpha-2C adrenergic receptor(Human)
Bayer Pharma Aktiengesellschaft

US Patent
LigandChemical structure of BindingDB Monomer ID 398507BDBM398507(US10323020, Example 1 | [4-(3,4-Dihydroisoquinolin...)
Affinity DataIC50: 82nMAssay Description:Antagonism against the adrenoreceptor α1A was tested using a recombinant human α1A receptor CHO cell line which additionally also recombina...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/10/2020
Entry Details
US Patent

TargetAlpha-2C adrenergic receptor(Human)
Bayer Pharma Aktiengesellschaft

US Patent
LigandChemical structure of BindingDB Monomer ID 398517BDBM398517(US10323020, Example 11 | 1-(5-{[4-(3,4-Dihydroisoq...)
Affinity DataIC50: 96nMAssay Description:Antagonism against the adrenoreceptor α1A was tested using a recombinant human α1A receptor CHO cell line which additionally also recombina...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/10/2020
Entry Details
US Patent