Compile Data Set for Download or QSAR
Report error Found 290 Enz. Inhib. hit(s) with all data for entry = 3516
TargetInterleukin-1 receptor-associated kinase 4(Human)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 50130661BDBM50130661(CHEMBL3634510 | US10329294, Example 162)
Affinity DataIC50: 0.200nMAssay Description:The kinase activity of IRAK4 is determined by its ability to catalyze the phosphorylation of a fluorescent polypeptide substrate. The extent of phosp...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/31/2020
Entry Details
US Patent

TargetInterleukin-1 receptor-associated kinase 4(Human)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 402564BDBM402564(US10329294, Example 138 | 5-{[(1R,2S)-2- aminocycl...)
Affinity DataIC50: 0.300nMAssay Description:The kinase activity of IRAK4 is determined by its ability to catalyze the phosphorylation of a fluorescent polypeptide substrate. The extent of phosp...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/31/2020
Entry Details
US Patent

TargetInterleukin-1 receptor-associated kinase 4(Human)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 402709BDBM402709(US10329294, Example 293 | 5-{[(1R,2S)-2- aminocycl...)
Affinity DataIC50: 0.400nMAssay Description:The kinase activity of IRAK4 is determined by its ability to catalyze the phosphorylation of a fluorescent polypeptide substrate. The extent of phosp...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/31/2020
Entry Details
US Patent

TargetInterleukin-1 receptor-associated kinase 4(Human)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 402668BDBM402668(US10329294, Example 243 | 5-[(R or S)-(4,4- difluo...)
Affinity DataIC50: 0.5nMAssay Description:The kinase activity of IRAK4 is determined by its ability to catalyze the phosphorylation of a fluorescent polypeptide substrate. The extent of phosp...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/31/2020
Entry Details
US Patent

TargetInterleukin-1 receptor-associated kinase 4(Human)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 402630BDBM402630(US10329294, Example 204 | US10329294, Example 206 ...)
Affinity DataIC50: 0.5nMAssay Description:The kinase activity of IRAK4 is determined by its ability to catalyze the phosphorylation of a fluorescent polypeptide substrate. The extent of phosp...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/31/2020
Entry Details
US Patent

TargetInterleukin-1 receptor-associated kinase 4(Human)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 402658BDBM402658(US10329294, Example 233 | 5-{[(3R,4R)- or (3S,4S)-...)
Affinity DataIC50: 0.5nMAssay Description:The kinase activity of IRAK4 is determined by its ability to catalyze the phosphorylation of a fluorescent polypeptide substrate. The extent of phosp...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/31/2020
Entry Details
US Patent

TargetInterleukin-1 receptor-associated kinase 4(Human)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 50130684BDBM50130684(CHEMBL3634502 | US10329294, Example 9)
Affinity DataIC50: 0.5nMAssay Description:The kinase activity of IRAK4 is determined by its ability to catalyze the phosphorylation of a fluorescent polypeptide substrate. The extent of phosp...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/31/2020
Entry Details
US Patent

TargetInterleukin-1 receptor-associated kinase 4(Human)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 402654BDBM402654(US10329294, Example 229 | 5-(3,8- diazabicyclo[3.2...)
Affinity DataIC50: 0.5nMAssay Description:The kinase activity of IRAK4 is determined by its ability to catalyze the phosphorylation of a fluorescent polypeptide substrate. The extent of phosp...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/31/2020
Entry Details
US Patent

TargetInterleukin-1 receptor-associated kinase 4(Human)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 402655BDBM402655(US10329294, Example 230 | 5-{[(3R,4S)- or (3S,4R)-...)
Affinity DataIC50: 0.5nMAssay Description:The kinase activity of IRAK4 is determined by its ability to catalyze the phosphorylation of a fluorescent polypeptide substrate. The extent of phosp...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/31/2020
Entry Details
US Patent

TargetInterleukin-1 receptor-associated kinase 4(Human)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 402681BDBM402681(US10329294, Example 258 | N-[3-(difluoromethyl)- 1...)
Affinity DataIC50: 0.5nMAssay Description:The kinase activity of IRAK4 is determined by its ability to catalyze the phosphorylation of a fluorescent polypeptide substrate. The extent of phosp...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/31/2020
Entry Details
US Patent

TargetInterleukin-1 receptor-associated kinase 4(Human)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 402586BDBM402586(US10329294, Example 160 | 5-[(3S)- or (3R)-azepan-...)
Affinity DataIC50: 0.5nMAssay Description:The kinase activity of IRAK4 is determined by its ability to catalyze the phosphorylation of a fluorescent polypeptide substrate. The extent of phosp...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/31/2020
Entry Details
US Patent

TargetInterleukin-1 receptor-associated kinase 4(Human)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 50095474BDBM50095474(CHEMBL3590478 | US10329294, Example 2)
Affinity DataIC50: 0.5nMAssay Description:The kinase activity of IRAK4 is determined by its ability to catalyze the phosphorylation of a fluorescent polypeptide substrate. The extent of phosp...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/31/2020
Entry Details
US Patent
PDB3D3D Structure (crystal)
TargetInterleukin-1 receptor-associated kinase 4(Human)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 402684BDBM402684(US10329294, Example 261 | N-[3-(difluoromethyl)- 1...)
Affinity DataIC50: 0.5nMAssay Description:The kinase activity of IRAK4 is determined by its ability to catalyze the phosphorylation of a fluorescent polypeptide substrate. The extent of phosp...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/31/2020
Entry Details
US Patent

TargetInterleukin-1 receptor-associated kinase 4(Human)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 50130689BDBM50130689(CHEMBL3634506 | US10329294, Example 91)
Affinity DataIC50: 0.5nMAssay Description:The kinase activity of IRAK4 is determined by its ability to catalyze the phosphorylation of a fluorescent polypeptide substrate. The extent of phosp...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/31/2020
Entry Details
US Patent

TargetInterleukin-1 receptor-associated kinase 4(Human)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 402677BDBM402677(US10329294, Example 253 | 5-[(3R,5R)-3-amino- 5-fl...)
Affinity DataIC50: 0.5nMAssay Description:The kinase activity of IRAK4 is determined by its ability to catalyze the phosphorylation of a fluorescent polypeptide substrate. The extent of phosp...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/31/2020
Entry Details
US Patent

TargetInterleukin-1 receptor-associated kinase 4(Human)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 402545BDBM402545(US10329294, Example 119 | 5-{[(1R,2S)-2- aminocycl...)
Affinity DataIC50: 0.5nMAssay Description:The kinase activity of IRAK4 is determined by its ability to catalyze the phosphorylation of a fluorescent polypeptide substrate. The extent of phosp...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/31/2020
Entry Details
US Patent

TargetInterleukin-1 receptor-associated kinase 4(Human)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 402451BDBM402451(US10329294, Example 25 | N-[3-(difluoromethyl)-1- ...)
Affinity DataIC50: 0.5nMAssay Description:The kinase activity of IRAK4 is determined by its ability to catalyze the phosphorylation of a fluorescent polypeptide substrate. The extent of phosp...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/31/2020
Entry Details
US Patent

TargetInterleukin-1 receptor-associated kinase 4(Human)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 402452BDBM402452(US10329294, Example 26 | N-[3-(difluoromethyl)-1- ...)
Affinity DataIC50: 0.5nMAssay Description:The kinase activity of IRAK4 is determined by its ability to catalyze the phosphorylation of a fluorescent polypeptide substrate. The extent of phosp...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/31/2020
Entry Details
US Patent

TargetInterleukin-1 receptor-associated kinase 4(Human)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 402516BDBM402516(US10329294, Example 90 | 5-[(3R)-3-aminopiperidin-...)
Affinity DataIC50: 0.5nMAssay Description:The kinase activity of IRAK4 is determined by its ability to catalyze the phosphorylation of a fluorescent polypeptide substrate. The extent of phosp...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/31/2020
Entry Details
US Patent

TargetInterleukin-1 receptor-associated kinase 4(Human)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 402605BDBM402605(US10329294, Example 179 | 5-[(3S,4R)- or (3R,4S)-3...)
Affinity DataIC50: 0.5nMAssay Description:The kinase activity of IRAK4 is determined by its ability to catalyze the phosphorylation of a fluorescent polypeptide substrate. The extent of phosp...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/31/2020
Entry Details
US Patent

TargetInterleukin-1 receptor-associated kinase 4(Human)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 402667BDBM402667(US10329294, Example 242 | N-[(R or S)-3- (difluoro...)
Affinity DataIC50: 0.5nMAssay Description:The kinase activity of IRAK4 is determined by its ability to catalyze the phosphorylation of a fluorescent polypeptide substrate. The extent of phosp...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/31/2020
Entry Details
US Patent

TargetInterleukin-1 receptor-associated kinase 4(Human)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 402606BDBM402606(US10329294, Example 180 | 5-[(4R)- or (4S)-(5-amin...)
Affinity DataIC50: 0.5nMAssay Description:The kinase activity of IRAK4 is determined by its ability to catalyze the phosphorylation of a fluorescent polypeptide substrate. The extent of phosp...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/31/2020
Entry Details
US Patent

TargetInterleukin-1 receptor-associated kinase 4(Human)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 50130664BDBM50130664(CHEMBL3634512 | US10329294, Example 149)
Affinity DataIC50: 0.5nMAssay Description:The kinase activity of IRAK4 is determined by its ability to catalyze the phosphorylation of a fluorescent polypeptide substrate. The extent of phosp...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/31/2020
Entry Details
US Patent

TargetInterleukin-1 receptor-associated kinase 4(Human)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 402659BDBM402659(US10329294, Example 234 | US10329294, Example 241 ...)
Affinity DataIC50: 0.600nMAssay Description:The kinase activity of IRAK4 is determined by its ability to catalyze the phosphorylation of a fluorescent polypeptide substrate. The extent of phosp...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/31/2020
Entry Details
US Patent

TargetInterleukin-1 receptor-associated kinase 4(Human)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 402659BDBM402659(US10329294, Example 234 | US10329294, Example 241 ...)
Affinity DataIC50: 0.600nMAssay Description:The kinase activity of IRAK4 is determined by its ability to catalyze the phosphorylation of a fluorescent polypeptide substrate. The extent of phosp...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/31/2020
Entry Details
US Patent

TargetInterleukin-1 receptor-associated kinase 4(Human)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 402680BDBM402680(US10329294, Example 257 | 5-{[(3R,5S)-5- fluoropip...)
Affinity DataIC50: 0.600nMAssay Description:The kinase activity of IRAK4 is determined by its ability to catalyze the phosphorylation of a fluorescent polypeptide substrate. The extent of phosp...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/31/2020
Entry Details
US Patent

TargetInterleukin-1 receptor-associated kinase 4(Human)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 402675BDBM402675(US10329294, Example 251 | 5-[(3R,5S)-3-amino- 5-fl...)
Affinity DataIC50: 0.700nMAssay Description:The kinase activity of IRAK4 is determined by its ability to catalyze the phosphorylation of a fluorescent polypeptide substrate. The extent of phosp...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/31/2020
Entry Details
US Patent

TargetInterleukin-1 receptor-associated kinase 4(Human)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 402660BDBM402660(US10329294, Example 235 | N-[3-(difluoromethyl)- 1...)
Affinity DataIC50: 0.700nMAssay Description:The kinase activity of IRAK4 is determined by its ability to catalyze the phosphorylation of a fluorescent polypeptide substrate. The extent of phosp...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/31/2020
Entry Details
US Patent

TargetInterleukin-1 receptor-associated kinase 4(Human)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 50095473BDBM50095473(CHEMBL3590477 | US10329294, Example 282)
Affinity DataIC50: 0.800nMAssay Description:The kinase activity of IRAK4 is determined by its ability to catalyze the phosphorylation of a fluorescent polypeptide substrate. The extent of phosp...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/31/2020
Entry Details
US Patent

TargetInterleukin-1 receptor-associated kinase 4(Human)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 50095532BDBM50095532(CHEMBL3590515 | US10329294, Example 173)
Affinity DataIC50: 0.800nMAssay Description:The kinase activity of IRAK4 is determined by its ability to catalyze the phosphorylation of a fluorescent polypeptide substrate. The extent of phosp...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/31/2020
Entry Details
US Patent

TargetInterleukin-1 receptor-associated kinase 4(Human)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 402707BDBM402707(US10329294, Example 291 | 5-{[(1R,2S)-2- aminocycl...)
Affinity DataIC50: 0.800nMAssay Description:The kinase activity of IRAK4 is determined by its ability to catalyze the phosphorylation of a fluorescent polypeptide substrate. The extent of phosp...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/31/2020
Entry Details
US Patent

TargetInterleukin-1 receptor-associated kinase 4(Human)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 50095534BDBM50095534(CHEMBL3590516 | US10329294, Example 252)
Affinity DataIC50: 0.800nMAssay Description:The kinase activity of IRAK4 is determined by its ability to catalyze the phosphorylation of a fluorescent polypeptide substrate. The extent of phosp...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/31/2020
Entry Details
US Patent

TargetInterleukin-1 receptor-associated kinase 4(Human)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 402708BDBM402708(US10329294, Example 292 | 5-{[(1R,2S)-2- aminocycl...)
Affinity DataIC50: 0.800nMAssay Description:The kinase activity of IRAK4 is determined by its ability to catalyze the phosphorylation of a fluorescent polypeptide substrate. The extent of phosp...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/31/2020
Entry Details
US Patent

TargetInterleukin-1 receptor-associated kinase 4(Human)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 402717BDBM402717(US10329294, Example 301 | 5-{[(1R,2S)-2- aminocycl...)
Affinity DataIC50: 0.800nMAssay Description:The kinase activity of IRAK4 is determined by its ability to catalyze the phosphorylation of a fluorescent polypeptide substrate. The extent of phosp...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/31/2020
Entry Details
US Patent

TargetInterleukin-1 receptor-associated kinase 4(Human)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 402502BDBM402502(US10329294, Example 76 | 5-{[(1R,2S)-2- aminocyclo...)
Affinity DataIC50: 0.900nMAssay Description:The kinase activity of IRAK4 is determined by its ability to catalyze the phosphorylation of a fluorescent polypeptide substrate. The extent of phosp...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/31/2020
Entry Details
US Patent

TargetInterleukin-1 receptor-associated kinase 4(Human)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 50095514BDBM50095514(CHEMBL3590491 | US10329294, Example 205)
Affinity DataIC50: 0.900nMAssay Description:The kinase activity of IRAK4 is determined by its ability to catalyze the phosphorylation of a fluorescent polypeptide substrate. The extent of phosp...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/31/2020
Entry Details
US Patent

TargetInterleukin-1 receptor-associated kinase 4(Human)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 402449BDBM402449(US10329294, Example 23 | 5-[(3R)-3- hydroxypiperid...)
Affinity DataIC50: 0.900nMAssay Description:The kinase activity of IRAK4 is determined by its ability to catalyze the phosphorylation of a fluorescent polypeptide substrate. The extent of phosp...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/31/2020
Entry Details
US Patent

TargetInterleukin-1 receptor-associated kinase 4(Human)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 402468BDBM402468(US10329294, Example 42 | 5-{[(1R,2S)-2- aminocyclo...)
Affinity DataIC50: 0.900nMAssay Description:The kinase activity of IRAK4 is determined by its ability to catalyze the phosphorylation of a fluorescent polypeptide substrate. The extent of phosp...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/31/2020
Entry Details
US Patent

TargetInterleukin-1 receptor-associated kinase 4(Human)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 402672BDBM402672(US10329294, Example 248 | 5-[(3S,5S)-3-amino- 5-fl...)
Affinity DataIC50: 0.900nMAssay Description:The kinase activity of IRAK4 is determined by its ability to catalyze the phosphorylation of a fluorescent polypeptide substrate. The extent of phosp...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/31/2020
Entry Details
US Patent

TargetInterleukin-1 receptor-associated kinase 4(Human)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 50095535BDBM50095535(CHEMBL3590517 | US10329294, Example 177)
Affinity DataIC50: 1nMAssay Description:The kinase activity of IRAK4 is determined by its ability to catalyze the phosphorylation of a fluorescent polypeptide substrate. The extent of phosp...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/31/2020
Entry Details
US Patent

TargetInterleukin-1 receptor-associated kinase 4(Human)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 402635BDBM402635(US10329294, Example 209 | 5-{[(1S,2R)- or (1R,2S)-...)
Affinity DataIC50: 1nMAssay Description:The kinase activity of IRAK4 is determined by its ability to catalyze the phosphorylation of a fluorescent polypeptide substrate. The extent of phosp...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/31/2020
Entry Details
US Patent

TargetInterleukin-1 receptor-associated kinase 4(Human)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 402636BDBM402636(US10329294, Example 210 | 5-{[(1S,2R)- or (1R,2S)-...)
Affinity DataIC50: 1nMAssay Description:The kinase activity of IRAK4 is determined by its ability to catalyze the phosphorylation of a fluorescent polypeptide substrate. The extent of phosp...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/31/2020
Entry Details
US Patent

TargetInterleukin-1 receptor-associated kinase 4(Human)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 402598BDBM402598(US10329294, Example 172 | 5-(3,8- diazabicyclo[3.2...)
Affinity DataIC50: 1nMAssay Description:The kinase activity of IRAK4 is determined by its ability to catalyze the phosphorylation of a fluorescent polypeptide substrate. The extent of phosp...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/31/2020
Entry Details
US Patent

TargetInterleukin-1 receptor-associated kinase 4(Human)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 402600BDBM402600(US10329294, Example 174 | 5-[(3R,4S)- or (3S,4R)-3...)
Affinity DataIC50: 1nMAssay Description:The kinase activity of IRAK4 is determined by its ability to catalyze the phosphorylation of a fluorescent polypeptide substrate. The extent of phosp...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/31/2020
Entry Details
US Patent

TargetInterleukin-1 receptor-associated kinase 4(Human)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 402530BDBM402530(US10329294, Example 104 | 5-{[(1R,2)S-2- aminocycl...)
Affinity DataIC50: 1nMAssay Description:The kinase activity of IRAK4 is determined by its ability to catalyze the phosphorylation of a fluorescent polypeptide substrate. The extent of phosp...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/31/2020
Entry Details
US Patent

TargetInterleukin-1 receptor-associated kinase 4(Human)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 402594BDBM402594(US10329294, Example 168 | 5-{[(1R,2S)-2- aminocycl...)
Affinity DataIC50: 1nMAssay Description:The kinase activity of IRAK4 is determined by its ability to catalyze the phosphorylation of a fluorescent polypeptide substrate. The extent of phosp...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/31/2020
Entry Details
US Patent

TargetInterleukin-1 receptor-associated kinase 4(Human)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 402710BDBM402710(US10329294, Example 294 | 5-{[(1R,2S)-2- aminocycl...)
Affinity DataIC50: 1nMAssay Description:The kinase activity of IRAK4 is determined by its ability to catalyze the phosphorylation of a fluorescent polypeptide substrate. The extent of phosp...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/31/2020
Entry Details
US Patent

TargetInterleukin-1 receptor-associated kinase 4(Human)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 402487BDBM402487(US10329294, Example 61 | 5-[(5S)-5-amino-3,3- difl...)
Affinity DataIC50: 1nMAssay Description:The kinase activity of IRAK4 is determined by its ability to catalyze the phosphorylation of a fluorescent polypeptide substrate. The extent of phosp...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/31/2020
Entry Details
US Patent

TargetInterleukin-1 receptor-associated kinase 4(Human)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 402711BDBM402711(US10329294, Example 295 | 5-{[(1R,2S)-2- aminocycl...)
Affinity DataIC50: 1nMAssay Description:The kinase activity of IRAK4 is determined by its ability to catalyze the phosphorylation of a fluorescent polypeptide substrate. The extent of phosp...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/31/2020
Entry Details
US Patent

TargetInterleukin-1 receptor-associated kinase 4(Human)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 402673BDBM402673(US10329294, Example 249 | 5-[(3S,5R)-3-amino- 5-fl...)
Affinity DataIC50: 1nMAssay Description:The kinase activity of IRAK4 is determined by its ability to catalyze the phosphorylation of a fluorescent polypeptide substrate. The extent of phosp...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/31/2020
Entry Details
US Patent

Displayed 1 to 50 (of 290 total ) | Next | Last >>
Jump to: