Compile Data Set for Download or QSAR
Report error Found 25 Enz. Inhib. hit(s) with all data for entry = 8606
TargetHsp90 co-chaperone Cdc37(Human)
Sloan-Kettering Institute For Cancer Research

US Patent
LigandChemical structure of BindingDB Monomer ID 406715BDBM406715(US10336757, Compound PU-DZ13)
Affinity DataEC50:  19.6nMAssay Description:The assay buffer (HFB) contained 20 mM HEPES (K) pH 7.3, 50 mM KCl, 5 mM MgCl2, 20 mM Na2MoO4, 0.01% NP40. Before each use, 0.1 mg/mL bovine gamma gl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2020
Entry Details
US Patent

TargetHsp90 co-chaperone Cdc37(Human)
Sloan-Kettering Institute For Cancer Research

US Patent
LigandChemical structure of BindingDB Monomer ID 406716BDBM406716(US10336757, Compound PU-DZ14)
Affinity DataEC50:  23.5nMAssay Description:The assay buffer (HFB) contained 20 mM HEPES (K) pH 7.3, 50 mM KCl, 5 mM MgCl2, 20 mM Na2MoO4, 0.01% NP40. Before each use, 0.1 mg/mL bovine gamma gl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2020
Entry Details
US Patent

TargetHsp90 co-chaperone Cdc37(Human)
Sloan-Kettering Institute For Cancer Research

US Patent
LigandChemical structure of BindingDB Monomer ID 50180302BDBM50180302(8-[(6-IODO-1,3-BENZODIOXOL-5-YL)THIO]-9-[3-(ISOPRO...)
Affinity DataEC50:  30.8nMAssay Description:The assay buffer (HFB) contained 20 mM HEPES (K) pH 7.3, 50 mM KCl, 5 mM MgCl2, 20 mM Na2MoO4, 0.01% NP40. Before each use, 0.1 mg/mL bovine gamma gl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2020
Entry Details
US Patent

TargetHsp90 co-chaperone Cdc37(Human)
Sloan-Kettering Institute For Cancer Research

US Patent
LigandChemical structure of BindingDB Monomer ID 406717BDBM406717(US10336757, Compound PU-DZ16)
Affinity DataEC50:  35.6nMAssay Description:The assay buffer (HFB) contained 20 mM HEPES (K) pH 7.3, 50 mM KCl, 5 mM MgCl2, 20 mM Na2MoO4, 0.01% NP40. Before each use, 0.1 mg/mL bovine gamma gl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2020
Entry Details
US Patent

TargetHsp90 co-chaperone Cdc37(Human)
Sloan-Kettering Institute For Cancer Research

US Patent
LigandChemical structure of BindingDB Monomer ID 406704BDBM406704(US10336757, Compound PU-BSI12)
Affinity DataEC50:  39.4nMAssay Description:The assay buffer (HFB) contained 20 mM HEPES (K) pH 7.3, 50 mM KCl, 5 mM MgCl2, 20 mM Na2MoO4, 0.01% NP40. Before each use, 0.1 mg/mL bovine gamma gl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2020
Entry Details
US Patent

TargetHsp90 co-chaperone Cdc37(Human)
Sloan-Kettering Institute For Cancer Research

US Patent
LigandChemical structure of BindingDB Monomer ID 406708BDBM406708(US10336757, Compound PU-BSI14)
Affinity DataEC50:  42.8nMAssay Description:The assay buffer (HFB) contained 20 mM HEPES (K) pH 7.3, 50 mM KCl, 5 mM MgCl2, 20 mM Na2MoO4, 0.01% NP40. Before each use, 0.1 mg/mL bovine gamma gl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2020
Entry Details
US Patent

TargetHsp90 co-chaperone Cdc37(Human)
Sloan-Kettering Institute For Cancer Research

US Patent
LigandChemical structure of BindingDB Monomer ID 406707BDBM406707(US10336757, Compound PU-BSI7)
Affinity DataEC50:  44.5nMAssay Description:The assay buffer (HFB) contained 20 mM HEPES (K) pH 7.3, 50 mM KCl, 5 mM MgCl2, 20 mM Na2MoO4, 0.01% NP40. Before each use, 0.1 mg/mL bovine gamma gl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2020
Entry Details
US Patent

TargetHsp90 co-chaperone Cdc37(Human)
Sloan-Kettering Institute For Cancer Research

US Patent
LigandChemical structure of BindingDB Monomer ID 50180301BDBM50180301(2-fluoro-8-(6-iodo-benzo[1,3]dioxol-5-ylmethyl)-9-...)
Affinity DataEC50:  60.7nMAssay Description:The assay buffer (HFB) contained 20 mM HEPES (K) pH 7.3, 50 mM KCl, 5 mM MgCl2, 20 mM Na2MoO4, 0.01% NP40. Before each use, 0.1 mg/mL bovine gamma gl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2020
Entry Details
US Patent

TargetHsp90 co-chaperone Cdc37(Human)
Sloan-Kettering Institute For Cancer Research

US Patent
LigandChemical structure of BindingDB Monomer ID 406705BDBM406705(US10336757, Compound PU-BSI6)
Affinity DataEC50:  60.8nMAssay Description:The assay buffer (HFB) contained 20 mM HEPES (K) pH 7.3, 50 mM KCl, 5 mM MgCl2, 20 mM Na2MoO4, 0.01% NP40. Before each use, 0.1 mg/mL bovine gamma gl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2020
Entry Details
US Patent

TargetHsp90 co-chaperone Cdc37(Human)
Sloan-Kettering Institute For Cancer Research

US Patent
LigandChemical structure of BindingDB Monomer ID 406709BDBM406709(US10336757, Compound PU-BSI15)
Affinity DataEC50:  68.2nMAssay Description:The assay buffer (HFB) contained 20 mM HEPES (K) pH 7.3, 50 mM KCl, 5 mM MgCl2, 20 mM Na2MoO4, 0.01% NP40. Before each use, 0.1 mg/mL bovine gamma gl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2020
Entry Details
US Patent

TargetHsp90 co-chaperone Cdc37(Human)
Sloan-Kettering Institute For Cancer Research

US Patent
LigandChemical structure of BindingDB Monomer ID 406719BDBM406719(US10336757, Compound PU-DZ17)
Affinity DataEC50:  92.3nMAssay Description:The assay buffer (HFB) contained 20 mM HEPES (K) pH 7.3, 50 mM KCl, 5 mM MgCl2, 20 mM Na2MoO4, 0.01% NP40. Before each use, 0.1 mg/mL bovine gamma gl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2020
Entry Details
US Patent

TargetHsp90 co-chaperone Cdc37(Human)
Sloan-Kettering Institute For Cancer Research

US Patent
LigandChemical structure of BindingDB Monomer ID 406710BDBM406710(US10336757, Compound PU-BSI4)
Affinity DataEC50:  95.3nMAssay Description:The assay buffer (HFB) contained 20 mM HEPES (K) pH 7.3, 50 mM KCl, 5 mM MgCl2, 20 mM Na2MoO4, 0.01% NP40. Before each use, 0.1 mg/mL bovine gamma gl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2020
Entry Details
US Patent

TargetHsp90 co-chaperone Cdc37(Human)
Sloan-Kettering Institute For Cancer Research

US Patent
LigandChemical structure of BindingDB Monomer ID 406711BDBM406711(US10336757, Compound PU-BSI10)
Affinity DataEC50:  105nMAssay Description:The assay buffer (HFB) contained 20 mM HEPES (K) pH 7.3, 50 mM KCl, 5 mM MgCl2, 20 mM Na2MoO4, 0.01% NP40. Before each use, 0.1 mg/mL bovine gamma gl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2020
Entry Details
US Patent

TargetHsp90 co-chaperone Cdc37(Human)
Sloan-Kettering Institute For Cancer Research

US Patent
LigandChemical structure of BindingDB Monomer ID 406720BDBM406720(US10336757, Compound PU-DZ18)
Affinity DataEC50:  107nMAssay Description:The assay buffer (HFB) contained 20 mM HEPES (K) pH 7.3, 50 mM KCl, 5 mM MgCl2, 20 mM Na2MoO4, 0.01% NP40. Before each use, 0.1 mg/mL bovine gamma gl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2020
Entry Details
US Patent

TargetHsp90 co-chaperone Cdc37(Human)
Sloan-Kettering Institute For Cancer Research

US Patent
LigandChemical structure of BindingDB Monomer ID 50180306BDBM50180306(8-(6-bromo-benzo[1,3]dioxol-5-ylsulfanyl)-9-(3-iso...)
Affinity DataEC50:  122nMAssay Description:The assay buffer (HFB) contained 20 mM HEPES (K) pH 7.3, 50 mM KCl, 5 mM MgCl2, 20 mM Na2MoO4, 0.01% NP40. Before each use, 0.1 mg/mL bovine gamma gl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2020
Entry Details
US Patent

TargetHsp90 co-chaperone Cdc37(Human)
Sloan-Kettering Institute For Cancer Research

US Patent
LigandChemical structure of BindingDB Monomer ID 406701BDBM406701(US10336757, Compound PU-HT70)
Affinity DataEC50:  147nMAssay Description:The assay buffer (HFB) contained 20 mM HEPES (K) pH 7.3, 50 mM KCl, 5 mM MgCl2, 20 mM Na2MoO4, 0.01% NP40. Before each use, 0.1 mg/mL bovine gamma gl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2020
Entry Details
US Patent

TargetHsp90 co-chaperone Cdc37(Human)
Sloan-Kettering Institute For Cancer Research

US Patent
LigandChemical structure of BindingDB Monomer ID 406718BDBM406718(US10336757, Compound PU-DZ15)
Affinity DataEC50:  166nMAssay Description:The assay buffer (HFB) contained 20 mM HEPES (K) pH 7.3, 50 mM KCl, 5 mM MgCl2, 20 mM Na2MoO4, 0.01% NP40. Before each use, 0.1 mg/mL bovine gamma gl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2020
Entry Details
US Patent

TargetHsp90 co-chaperone Cdc37(Human)
Sloan-Kettering Institute For Cancer Research

US Patent
LigandChemical structure of BindingDB Monomer ID 406700BDBM406700(US10336757, Compound PU-DZ10)
Affinity DataEC50:  193nMAssay Description:The assay buffer (HFB) contained 20 mM HEPES (K) pH 7.3, 50 mM KCl, 5 mM MgCl2, 20 mM Na2MoO4, 0.01% NP40. Before each use, 0.1 mg/mL bovine gamma gl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2020
Entry Details
US Patent

TargetHsp90 co-chaperone Cdc37(Human)
Sloan-Kettering Institute For Cancer Research

US Patent
LigandChemical structure of BindingDB Monomer ID 406712BDBM406712(US10336757, Compound PU-BSI3)
Affinity DataEC50:  199nMAssay Description:The assay buffer (HFB) contained 20 mM HEPES (K) pH 7.3, 50 mM KCl, 5 mM MgCl2, 20 mM Na2MoO4, 0.01% NP40. Before each use, 0.1 mg/mL bovine gamma gl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2020
Entry Details
US Patent

TargetHsp90 co-chaperone Cdc37(Human)
Sloan-Kettering Institute For Cancer Research

US Patent
LigandChemical structure of BindingDB Monomer ID 406713BDBM406713(US10336757, Compound PU-BSI16)
Affinity DataEC50:  202nMAssay Description:The assay buffer (HFB) contained 20 mM HEPES (K) pH 7.3, 50 mM KCl, 5 mM MgCl2, 20 mM Na2MoO4, 0.01% NP40. Before each use, 0.1 mg/mL bovine gamma gl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2020
Entry Details
US Patent

TargetHsp90 co-chaperone Cdc37(Human)
Sloan-Kettering Institute For Cancer Research

US Patent
LigandChemical structure of BindingDB Monomer ID 406706BDBM406706(US10336757, Compound PU-BSI11)
Affinity DataEC50:  210nMAssay Description:The assay buffer (HFB) contained 20 mM HEPES (K) pH 7.3, 50 mM KCl, 5 mM MgCl2, 20 mM Na2MoO4, 0.01% NP40. Before each use, 0.1 mg/mL bovine gamma gl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2020
Entry Details
US Patent

TargetHsp90 co-chaperone Cdc37(Human)
Sloan-Kettering Institute For Cancer Research

US Patent
LigandChemical structure of BindingDB Monomer ID 406697BDBM406697(US10336757, Compound PU-HT65)
Affinity DataEC50:  213nMAssay Description:The assay buffer (HFB) contained 20 mM HEPES (K) pH 7.3, 50 mM KCl, 5 mM MgCl2, 20 mM Na2MoO4, 0.01% NP40. Before each use, 0.1 mg/mL bovine gamma gl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2020
Entry Details
US Patent

TargetHsp90 co-chaperone Cdc37(Human)
Sloan-Kettering Institute For Cancer Research

US Patent
LigandChemical structure of BindingDB Monomer ID 406714BDBM406714(US10336757, Compound PU-DZ12)
Affinity DataEC50:  219nMAssay Description:The assay buffer (HFB) contained 20 mM HEPES (K) pH 7.3, 50 mM KCl, 5 mM MgCl2, 20 mM Na2MoO4, 0.01% NP40. Before each use, 0.1 mg/mL bovine gamma gl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2020
Entry Details
US Patent

TargetHsp90 co-chaperone Cdc37(Human)
Sloan-Kettering Institute For Cancer Research

US Patent
LigandChemical structure of BindingDB Monomer ID 406703BDBM406703(US10336757, Compound PU-HT133)
Affinity DataEC50:  813nMAssay Description:The assay buffer (HFB) contained 20 mM HEPES (K) pH 7.3, 50 mM KCl, 5 mM MgCl2, 20 mM Na2MoO4, 0.01% NP40. Before each use, 0.1 mg/mL bovine gamma gl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2020
Entry Details
US Patent

TargetHsp90 co-chaperone Cdc37(Human)
Sloan-Kettering Institute For Cancer Research

US Patent
LigandChemical structure of BindingDB Monomer ID 406702BDBM406702(US10336757, Compound PU-HT78)
Affinity DataEC50:  9.56E+3nMAssay Description:The assay buffer (HFB) contained 20 mM HEPES (K) pH 7.3, 50 mM KCl, 5 mM MgCl2, 20 mM Na2MoO4, 0.01% NP40. Before each use, 0.1 mg/mL bovine gamma gl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2020
Entry Details
US Patent