Compile Data Set for Download or QSAR
Report error Found 402 Enz. Inhib. hit(s) with all data for entry = 8612
TargetHistone deacetylase 6(Human)
Selenity Therapeutics (Bermuda)

US Patent
LigandChemical structure of BindingDB Monomer ID 408339BDBM408339(5-(5-(difluoromethyl)-1,3,4-oxadiazol-2-yl)-N-(1-(...)
Affinity DataIC50: 6nMAssay Description:All enzymatic reactions were conducted in duplicate at room temperature for 17 hours in a 50 μl mixture containing HDAC assay buffer (50 mM Tris...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2020
Entry Details
US Patent

TargetHistone deacetylase 6(Human)
Selenity Therapeutics (Bermuda)

US Patent
LigandChemical structure of BindingDB Monomer ID 408335BDBM408335(N-(1-(2-chlorophenyl)cyclopropyl)-5-(5-(difluorome...)
Affinity DataIC50: 6nMAssay Description:All enzymatic reactions were conducted in duplicate at room temperature for 17 hours in a 50 μl mixture containing HDAC assay buffer (50 mM Tris...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2020
Entry Details
US Patent

TargetHistone deacetylase 6(Human)
Selenity Therapeutics (Bermuda)

US Patent
LigandChemical structure of BindingDB Monomer ID 408288BDBM408288(5-(5-(difluoromethyl)-1,3,4-oxadiazol-2-yl)-N-(1-(...)
Affinity DataIC50: 6nMAssay Description:All enzymatic reactions were conducted in duplicate at room temperature for 17 hours in a 50 μl mixture containing HDAC assay buffer (50 mM Tris...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2020
Entry Details
US Patent

TargetHistone deacetylase 6(Human)
Selenity Therapeutics (Bermuda)

US Patent
LigandChemical structure of BindingDB Monomer ID 408345BDBM408345(N-(1-(2-chloro-4-fluorophenyl)cyclopropyl)-5-(5-(d...)
Affinity DataIC50: 8nMAssay Description:All enzymatic reactions were conducted in duplicate at room temperature for 17 hours in a 50 μl mixture containing HDAC assay buffer (50 mM Tris...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2020
Entry Details
US Patent

TargetHistone deacetylase 6(Human)
Selenity Therapeutics (Bermuda)

US Patent
LigandChemical structure of BindingDB Monomer ID 408287BDBM408287(5-(5-(difluoromethyl)-1,3,4-oxadiazol-2-yl)-N-(1-(...)
Affinity DataIC50: 9nMAssay Description:All enzymatic reactions were conducted in duplicate at room temperature for 17 hours in a 50 μl mixture containing HDAC assay buffer (50 mM Tris...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2020
Entry Details
US Patent

TargetHistone deacetylase 6(Human)
Selenity Therapeutics (Bermuda)

US Patent
LigandChemical structure of BindingDB Monomer ID 408359BDBM408359(N-(1-(5-chloro-2-fluorophenyl)cyclopropyl)-5-(5-(d...)
Affinity DataIC50: 14nMAssay Description:All enzymatic reactions were conducted in duplicate at room temperature for 17 hours in a 50 μl mixture containing HDAC assay buffer (50 mM Tris...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2020
Entry Details
US Patent

TargetHistone deacetylase 6(Human)
Selenity Therapeutics (Bermuda)

US Patent
LigandChemical structure of BindingDB Monomer ID 408334BDBM408334(N-(1-(3-chlorophenyl)cyclopropyl)-5-(5-(difluorome...)
Affinity DataIC50: 15nMAssay Description:All enzymatic reactions were conducted in duplicate at room temperature for 17 hours in a 50 μl mixture containing HDAC assay buffer (50 mM Tris...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2020
Entry Details
US Patent

TargetHistone deacetylase 6(Human)
Selenity Therapeutics (Bermuda)

US Patent
LigandChemical structure of BindingDB Monomer ID 408340BDBM408340(5-(5-(difluoromethyl)-1,3,4-oxadiazol-2-yl)-N-(1-(...)
Affinity DataIC50: 15nMAssay Description:All enzymatic reactions were conducted in duplicate at room temperature for 17 hours in a 50 μl mixture containing HDAC assay buffer (50 mM Tris...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2020
Entry Details
US Patent

TargetHistone deacetylase 6(Human)
Selenity Therapeutics (Bermuda)

US Patent
LigandChemical structure of BindingDB Monomer ID 408320BDBM408320(US10357493, Example 38(+))
Affinity DataIC50: 15nMAssay Description:All enzymatic reactions were conducted in duplicate at room temperature for 17 hours in a 50 μl mixture containing HDAC assay buffer (50 mM Tris...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2020
Entry Details
US Patent

TargetHistone deacetylase 6(Human)
Selenity Therapeutics (Bermuda)

US Patent
LigandChemical structure of BindingDB Monomer ID 408390BDBM408390(US10357493, Example 106)
Affinity DataIC50: 16nMAssay Description:All enzymatic reactions were conducted in duplicate at room temperature for 17 hours in a 50 μl mixture containing HDAC assay buffer (50 mM Tris...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2020
Entry Details
US Patent

TargetHistone deacetylase 6(Human)
Selenity Therapeutics (Bermuda)

US Patent
LigandChemical structure of BindingDB Monomer ID 408332BDBM408332(5-(5-(difluoromethyl)-1,3,4-oxadiazol-2-yl)-N-(1-(...)
Affinity DataIC50: 16nMAssay Description:All enzymatic reactions were conducted in duplicate at room temperature for 17 hours in a 50 μl mixture containing HDAC assay buffer (50 mM Tris...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2020
Entry Details
US Patent

TargetHistone deacetylase 6(Human)
Selenity Therapeutics (Bermuda)

US Patent
LigandChemical structure of BindingDB Monomer ID 408380BDBM408380(US10357493, Example 98)
Affinity DataIC50: 16nMAssay Description:All enzymatic reactions were conducted in duplicate at room temperature for 17 hours in a 50 μl mixture containing HDAC assay buffer (50 mM Tris...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2020
Entry Details
US Patent

TargetHistone deacetylase 6(Human)
Selenity Therapeutics (Bermuda)

US Patent
LigandChemical structure of BindingDB Monomer ID 408388BDBM408388(N-(2-((5-(5-(difluoromethyl)-1,3,4-oxadiazol-2-yl)...)
Affinity DataIC50: 16nMAssay Description:All enzymatic reactions were conducted in duplicate at room temperature for 17 hours in a 50 μl mixture containing HDAC assay buffer (50 mM Tris...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2020
Entry Details
US Patent

TargetHistone deacetylase 6(Human)
Selenity Therapeutics (Bermuda)

US Patent
LigandChemical structure of BindingDB Monomer ID 408356BDBM408356(N-(1-(3-chloro-2-fluorophenyl)cyclopropyl)-5-(5-(d...)
Affinity DataIC50: 17nMAssay Description:All enzymatic reactions were conducted in duplicate at room temperature for 17 hours in a 50 μl mixture containing HDAC assay buffer (50 mM Tris...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2020
Entry Details
US Patent

TargetHistone deacetylase 6(Human)
Selenity Therapeutics (Bermuda)

US Patent
LigandChemical structure of BindingDB Monomer ID 408400BDBM408400(N-(2-(4-(difluoromethoxy)-2-fluorophenyl)-2-((5-(5...)
Affinity DataIC50: 17nMAssay Description:All enzymatic reactions were conducted in duplicate at room temperature for 17 hours in a 50 μl mixture containing HDAC assay buffer (50 mM Tris...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2020
Entry Details
US Patent

TargetHistone deacetylase 6(Human)
Selenity Therapeutics (Bermuda)

US Patent
LigandChemical structure of BindingDB Monomer ID 408398BDBM408398(N-(2-(4-(difluoromethoxy)phenyl)-2-((5-(5-(difluor...)
Affinity DataIC50: 18nMAssay Description:All enzymatic reactions were conducted in duplicate at room temperature for 17 hours in a 50 μl mixture containing HDAC assay buffer (50 mM Tris...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2020
Entry Details
US Patent

TargetHistone deacetylase 6(Human)
Selenity Therapeutics (Bermuda)

US Patent
LigandChemical structure of BindingDB Monomer ID 408431BDBM408431(N-(2-(4-(difluoromethoxy)-2-fluorophenyl)-2-((5-(5...)
Affinity DataIC50: 18nMAssay Description:All enzymatic reactions were conducted in duplicate at room temperature for 17 hours in a 50 μl mixture containing HDAC assay buffer (50 mM Tris...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2020
Entry Details
US Patent

TargetHistone deacetylase 6(Human)
Selenity Therapeutics (Bermuda)

US Patent
LigandChemical structure of BindingDB Monomer ID 408357BDBM408357(5-(5-(difluoromethyl)-1,3,4-oxadiazol-2-yl)-N-(1-(...)
Affinity DataIC50: 19nMAssay Description:All enzymatic reactions were conducted in duplicate at room temperature for 17 hours in a 50 μl mixture containing HDAC assay buffer (50 mM Tris...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2020
Entry Details
US Patent

TargetHistone deacetylase 6(Human)
Selenity Therapeutics (Bermuda)

US Patent
LigandChemical structure of BindingDB Monomer ID 408432BDBM408432(N-(2-(4-(difluoromethoxy)-2-fluorophenyl)-2-((5-(5...)
Affinity DataIC50: 19nMAssay Description:All enzymatic reactions were conducted in duplicate at room temperature for 17 hours in a 50 μl mixture containing HDAC assay buffer (50 mM Tris...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2020
Entry Details
US Patent

TargetHistone deacetylase 6(Human)
Selenity Therapeutics (Bermuda)

US Patent
LigandChemical structure of BindingDB Monomer ID 408437BDBM408437(N-(2-((5-(5-(difluoromethyl)-1,3,4-oxadiazol-2-yl)...)
Affinity DataIC50: 20nMAssay Description:All enzymatic reactions were conducted in duplicate at room temperature for 17 hours in a 50 μl mixture containing HDAC assay buffer (50 mM Tris...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2020
Entry Details
US Patent

TargetHistone deacetylase 6(Human)
Selenity Therapeutics (Bermuda)

US Patent
LigandChemical structure of BindingDB Monomer ID 408338BDBM408338(5-(5-(difluoromethyl)-1,3,4-oxadiazol-2-yl)-N-(1-(...)
Affinity DataIC50: 20nMAssay Description:All enzymatic reactions were conducted in duplicate at room temperature for 17 hours in a 50 μl mixture containing HDAC assay buffer (50 mM Tris...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2020
Entry Details
US Patent

TargetHistone deacetylase 6(Human)
Selenity Therapeutics (Bermuda)

US Patent
LigandChemical structure of BindingDB Monomer ID 408342BDBM408342(5-(5-(difluoromethyl)-1,3,4-oxadiazol-2-yl)-N-(1-(...)
Affinity DataIC50: 21nMAssay Description:All enzymatic reactions were conducted in duplicate at room temperature for 17 hours in a 50 μl mixture containing HDAC assay buffer (50 mM Tris...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2020
Entry Details
US Patent

TargetHistone deacetylase 6(Human)
Selenity Therapeutics (Bermuda)

US Patent
LigandChemical structure of BindingDB Monomer ID 408300BDBM408300(US10357493, Example 20(+))
Affinity DataIC50: 21nMAssay Description:All enzymatic reactions were conducted in duplicate at room temperature for 17 hours in a 50 μl mixture containing HDAC assay buffer (50 mM Tris...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2020
Entry Details
US Patent

TargetHistone deacetylase 6(Human)
Selenity Therapeutics (Bermuda)

US Patent
LigandChemical structure of BindingDB Monomer ID 408396BDBM408396(US10357493, Example 113)
Affinity DataIC50: 21nMAssay Description:All enzymatic reactions were conducted in duplicate at room temperature for 17 hours in a 50 μl mixture containing HDAC assay buffer (50 mM Tris...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2020
Entry Details
US Patent

TargetHistone deacetylase 6(Human)
Selenity Therapeutics (Bermuda)

US Patent
LigandChemical structure of BindingDB Monomer ID 408376BDBM408376(US10357493, Example 91)
Affinity DataIC50: 21nMAssay Description:All enzymatic reactions were conducted in duplicate at room temperature for 17 hours in a 50 μl mixture containing HDAC assay buffer (50 mM Tris...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2020
Entry Details
US Patent

TargetHistone deacetylase 6(Human)
Selenity Therapeutics (Bermuda)

US Patent
LigandChemical structure of BindingDB Monomer ID 408337BDBM408337(5-(5-(difluoromethyl)-1,3,4-oxadiazol-2-yl)-N-(1-(...)
Affinity DataIC50: 22nMAssay Description:All enzymatic reactions were conducted in duplicate at room temperature for 17 hours in a 50 μl mixture containing HDAC assay buffer (50 mM Tris...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2020
Entry Details
US Patent

TargetHistone deacetylase 6(Human)
Selenity Therapeutics (Bermuda)

US Patent
LigandChemical structure of BindingDB Monomer ID 408385BDBM408385(US10357493, Example 101(+))
Affinity DataIC50: 22nMAssay Description:All enzymatic reactions were conducted in duplicate at room temperature for 17 hours in a 50 μl mixture containing HDAC assay buffer (50 mM Tris...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2020
Entry Details
US Patent

TargetHistone deacetylase 6(Human)
Selenity Therapeutics (Bermuda)

US Patent
LigandChemical structure of BindingDB Monomer ID 408343BDBM408343(5-(5-(difluoromethyl)-1,3,4-oxadiazol-2-yl)-N-(1-(...)
Affinity DataIC50: 22nMAssay Description:All enzymatic reactions were conducted in duplicate at room temperature for 17 hours in a 50 μl mixture containing HDAC assay buffer (50 mM Tris...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2020
Entry Details
US Patent

TargetHistone deacetylase 6(Human)
Selenity Therapeutics (Bermuda)

US Patent
LigandChemical structure of BindingDB Monomer ID 408344BDBM408344(5-(5-(difluoromethyl)-1,3,4-oxadiazol-2-yl)-N-(1-(...)
Affinity DataIC50: 22nMAssay Description:All enzymatic reactions were conducted in duplicate at room temperature for 17 hours in a 50 μl mixture containing HDAC assay buffer (50 mM Tris...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2020
Entry Details
US Patent

TargetHistone deacetylase 6(Human)
Selenity Therapeutics (Bermuda)

US Patent
LigandChemical structure of BindingDB Monomer ID 408365BDBM408365(US10357493, Example 80)
Affinity DataIC50: 23nMAssay Description:All enzymatic reactions were conducted in duplicate at room temperature for 17 hours in a 50 μl mixture containing HDAC assay buffer (50 mM Tris...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2020
Entry Details
US Patent

TargetHistone deacetylase 6(Human)
Selenity Therapeutics (Bermuda)

US Patent
LigandChemical structure of BindingDB Monomer ID 408281BDBM408281(5-(5-(difluoromethyl)-1,3,4-oxadiazol-2-yl)-N-(1-p...)
Affinity DataIC50: 23nMAssay Description:All enzymatic reactions were conducted in duplicate at room temperature for 17 hours in a 50 μl mixture containing HDAC assay buffer (50 mM Tris...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2020
Entry Details
US Patent

TargetHistone deacetylase 6(Human)
Selenity Therapeutics (Bermuda)

US Patent
LigandChemical structure of BindingDB Monomer ID 408329BDBM408329(5-(5-(difluoromethyl)-1,3,4-oxadiazol-2-yl)-N-(1-(...)
Affinity DataIC50: 23nMAssay Description:All enzymatic reactions were conducted in duplicate at room temperature for 17 hours in a 50 μl mixture containing HDAC assay buffer (50 mM Tris...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2020
Entry Details
US Patent

TargetHistone deacetylase 6(Human)
Selenity Therapeutics (Bermuda)

US Patent
LigandChemical structure of BindingDB Monomer ID 408434BDBM408434(N-(2-(4-(difluoromethoxy)-2-fluorophenyl)-2-((5-(5...)
Affinity DataIC50: 23nMAssay Description:All enzymatic reactions were conducted in duplicate at room temperature for 17 hours in a 50 μl mixture containing HDAC assay buffer (50 mM Tris...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2020
Entry Details
US Patent

TargetHistone deacetylase 6(Human)
Selenity Therapeutics (Bermuda)

US Patent
LigandChemical structure of BindingDB Monomer ID 408336BDBM408336(5-(5-(difluoromethyl)-1,3,4-oxadiazol-2-yl)-N-(1-(...)
Affinity DataIC50: 23nMAssay Description:All enzymatic reactions were conducted in duplicate at room temperature for 17 hours in a 50 μl mixture containing HDAC assay buffer (50 mM Tris...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2020
Entry Details
US Patent

TargetHistone deacetylase 6(Human)
Selenity Therapeutics (Bermuda)

US Patent
LigandChemical structure of BindingDB Monomer ID 408469BDBM408469(N-(2-(4-chlorophenyl)-2-((5-(5-(difluoromethyl)-1,...)
Affinity DataIC50: 24nMAssay Description:All enzymatic reactions were conducted in duplicate at room temperature for 17 hours in a 50 μl mixture containing HDAC assay buffer (50 mM Tris...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2020
Entry Details
US Patent

TargetHistone deacetylase 6(Human)
Selenity Therapeutics (Bermuda)

US Patent
LigandChemical structure of BindingDB Monomer ID 408410BDBM408410(N-(3-((5-(5-(difluoromethyl)-1,3,4-oxadiazol-2-yl)...)
Affinity DataIC50: 26nMAssay Description:All enzymatic reactions were conducted in duplicate at room temperature for 17 hours in a 50 μl mixture containing HDAC assay buffer (50 mM Tris...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2020
Entry Details
US Patent

TargetHistone deacetylase 6(Human)
Selenity Therapeutics (Bermuda)

US Patent
LigandChemical structure of BindingDB Monomer ID 408330BDBM408330(N-(1-(4-bromophenyl)cyclopropyl)-5-(5-(difluoromet...)
Affinity DataIC50: 27nMAssay Description:All enzymatic reactions were conducted in duplicate at room temperature for 17 hours in a 50 μl mixture containing HDAC assay buffer (50 mM Tris...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2020
Entry Details
US Patent

TargetHistone deacetylase 6(Human)
Selenity Therapeutics (Bermuda)

US Patent
LigandChemical structure of BindingDB Monomer ID 408391BDBM408391(N-(2-((5-(5-(difluoromethyl)-1,3,4-oxadiazol-2-yl)...)
Affinity DataIC50: 27nMAssay Description:All enzymatic reactions were conducted in duplicate at room temperature for 17 hours in a 50 μl mixture containing HDAC assay buffer (50 mM Tris...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2020
Entry Details
US Patent

TargetHistone deacetylase 6(Human)
Selenity Therapeutics (Bermuda)

US Patent
LigandChemical structure of BindingDB Monomer ID 408381BDBM408381(US10357493, Example 99-R)
Affinity DataIC50: 28nMAssay Description:All enzymatic reactions were conducted in duplicate at room temperature for 17 hours in a 50 μl mixture containing HDAC assay buffer (50 mM Tris...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2020
Entry Details
US Patent

TargetHistone deacetylase 6(Human)
Selenity Therapeutics (Bermuda)

US Patent
LigandChemical structure of BindingDB Monomer ID 408347BDBM408347(N-(1-(6-bromopyridin-3-yl)cyclopropyl)-5-(5-(diflu...)
Affinity DataIC50: 28nMAssay Description:All enzymatic reactions were conducted in duplicate at room temperature for 17 hours in a 50 μl mixture containing HDAC assay buffer (50 mM Tris...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2020
Entry Details
US Patent

TargetHistone deacetylase 6(Human)
Selenity Therapeutics (Bermuda)

US Patent
LigandChemical structure of BindingDB Monomer ID 408371BDBM408371(US10357493, Example 86)
Affinity DataIC50: 28nMAssay Description:All enzymatic reactions were conducted in duplicate at room temperature for 17 hours in a 50 μl mixture containing HDAC assay buffer (50 mM Tris...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2020
Entry Details
US Patent

TargetHistone deacetylase 6(Human)
Selenity Therapeutics (Bermuda)

US Patent
LigandChemical structure of BindingDB Monomer ID 408393BDBM408393(N-(2-((5-(5-(difluoromethyl)-1,3,4-oxadiazol-2-yl)...)
Affinity DataIC50: 28nMAssay Description:All enzymatic reactions were conducted in duplicate at room temperature for 17 hours in a 50 μl mixture containing HDAC assay buffer (50 mM Tris...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2020
Entry Details
US Patent

TargetHistone deacetylase 6(Human)
Selenity Therapeutics (Bermuda)

US Patent
LigandChemical structure of BindingDB Monomer ID 408360BDBM408360(N-(1-(2-chloro-3-methylphenyl)cyclopropyl)-5-(5-(d...)
Affinity DataIC50: 28nMAssay Description:All enzymatic reactions were conducted in duplicate at room temperature for 17 hours in a 50 μl mixture containing HDAC assay buffer (50 mM Tris...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2020
Entry Details
US Patent

TargetHistone deacetylase 6(Human)
Selenity Therapeutics (Bermuda)

US Patent
LigandChemical structure of BindingDB Monomer ID 408373BDBM408373(US10357493, Example 88)
Affinity DataIC50: 29nMAssay Description:All enzymatic reactions were conducted in duplicate at room temperature for 17 hours in a 50 μl mixture containing HDAC assay buffer (50 mM Tris...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2020
Entry Details
US Patent

TargetHistone deacetylase 6(Human)
Selenity Therapeutics (Bermuda)

US Patent
LigandChemical structure of BindingDB Monomer ID 408403BDBM408403(N-(2-((5-(5-(difluoromethyl)-1,3,4-oxadiazol-2-yl)...)
Affinity DataIC50: 29nMAssay Description:All enzymatic reactions were conducted in duplicate at room temperature for 17 hours in a 50 μl mixture containing HDAC assay buffer (50 mM Tris...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2020
Entry Details
US Patent

TargetHistone deacetylase 6(Human)
Selenity Therapeutics (Bermuda)

US Patent
LigandChemical structure of BindingDB Monomer ID 408459BDBM408459(N-(2-((5-(5-(difluoromethyl)-1,3,4-oxadiazol-2-yl)...)
Affinity DataIC50: 29nMAssay Description:All enzymatic reactions were conducted in duplicate at room temperature for 17 hours in a 50 μl mixture containing HDAC assay buffer (50 mM Tris...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2020
Entry Details
US Patent

TargetHistone deacetylase 6(Human)
Selenity Therapeutics (Bermuda)

US Patent
LigandChemical structure of BindingDB Monomer ID 408314BDBM408314(N-(1-(4-(difluoromethoxy)-2-fluorophenyl)cycloprop...)
Affinity DataIC50: 29nMAssay Description:All enzymatic reactions were conducted in duplicate at room temperature for 17 hours in a 50 μl mixture containing HDAC assay buffer (50 mM Tris...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2020
Entry Details
US Patent

TargetHistone deacetylase 6(Human)
Selenity Therapeutics (Bermuda)

US Patent
LigandChemical structure of BindingDB Monomer ID 408319BDBM408319(N-(2-((5-(5-(difluoromethyl)-1,3,4-oxadiazol-2-yl)...)
Affinity DataIC50: 29nMAssay Description:All enzymatic reactions were conducted in duplicate at room temperature for 17 hours in a 50 μl mixture containing HDAC assay buffer (50 mM Tris...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2020
Entry Details
US Patent

TargetHistone deacetylase 6(Human)
Selenity Therapeutics (Bermuda)

US Patent
LigandChemical structure of BindingDB Monomer ID 408333BDBM408333(N-(1-(4-chlorophenyl)cyclopropyl)-5-(5-(difluorome...)
Affinity DataIC50: 30nMAssay Description:All enzymatic reactions were conducted in duplicate at room temperature for 17 hours in a 50 μl mixture containing HDAC assay buffer (50 mM Tris...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2020
Entry Details
US Patent

TargetHistone deacetylase 6(Human)
Selenity Therapeutics (Bermuda)

US Patent
LigandChemical structure of BindingDB Monomer ID 408291BDBM408291(US10357493, Example 13(+))
Affinity DataIC50: 30nMAssay Description:All enzymatic reactions were conducted in duplicate at room temperature for 17 hours in a 50 μl mixture containing HDAC assay buffer (50 mM Tris...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2020
Entry Details
US Patent

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