Compile Data Set for Download or QSAR
Report error Found 249 Enz. Inhib. hit(s) with all data for entry = 8634
TargetTyrosine-protein kinase JAK2(Human)
Hutchison Medipharma

US Patent
LigandChemical structure of BindingDB Monomer ID 294511BDBM294511(US10111875, Compound 206 | US10369153, Compound 20...)
Affinity DataIC50: 0.5nMAssay Description:JAK1/2/3 kinase assay are performed in vitro using Kit-Tyr 6 Peptide (Invitrogen, Cat. No. PV4122). TYK2 kinase assay are performed in vitro using Z&...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2020
Entry Details
US Patent

TargetTyrosine-protein kinase JAK1(Human)
Hutchison Medipharma

US Patent
LigandChemical structure of BindingDB Monomer ID 294511BDBM294511(US10111875, Compound 206 | US10369153, Compound 20...)
Affinity DataIC50: 2nMAssay Description:JAK1/2/3 kinase assay are performed in vitro using Kit-Tyr 6 Peptide (Invitrogen, Cat. No. PV4122). TYK2 kinase assay are performed in vitro using Z&...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2020
Entry Details
US Patent

TargetTyrosine-protein kinase JAK1(Human)
Hutchison Medipharma

US Patent
LigandChemical structure of BindingDB Monomer ID 228640BDBM228640(US9346810, 234 | US10111875, Compound 234 | US1036...)
Affinity DataIC50: 5.10nMAssay Description:JAK1/2/3 kinase assay are performed in vitro using Kit-Tyr 6 Peptide (Invitrogen, Cat. No. PV4122). TYK2 kinase assay are performed in vitro using Z&...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2020
Entry Details
US Patent

TargetTyrosine-protein kinase JAK1(Human)
Hutchison Medipharma

US Patent
LigandChemical structure of BindingDB Monomer ID 228728BDBM228728(US9346810, 94 | US10111875, Compound 142 | US10369...)
Affinity DataIC50: 9.40nMAssay Description:JAK1/2/3 kinase assay are performed in vitro using Kit-Tyr 6 Peptide (Invitrogen, Cat. No. PV4122). TYK2 kinase assay are performed in vitro using Z&...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2020
Entry Details
US Patent

TargetTyrosine-protein kinase JAK1(Human)
Hutchison Medipharma

US Patent
LigandChemical structure of BindingDB Monomer ID 228641BDBM228641(US9346810, 199 | US10369153, Compound 199)
Affinity DataIC50: 14nMAssay Description:JAK1/2/3 kinase assay are performed in vitro using Kit-Tyr 6 Peptide (Invitrogen, Cat. No. PV4122). TYK2 kinase assay are performed in vitro using Z&...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2020
Entry Details
US Patent

TargetTyrosine-protein kinase JAK1(Human)
Hutchison Medipharma

US Patent
LigandChemical structure of BindingDB Monomer ID 228644BDBM228644(US9346810, 105 | US10111875, Compound 105 | US1036...)
Affinity DataIC50: 14nMAssay Description:JAK1/2/3 kinase assay are performed in vitro using Kit-Tyr 6 Peptide (Invitrogen, Cat. No. PV4122). TYK2 kinase assay are performed in vitro using Z&...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2020
Entry Details
US Patent

TargetTyrosine-protein kinase JAK2(Human)
Hutchison Medipharma

US Patent
LigandChemical structure of BindingDB Monomer ID 228640BDBM228640(US9346810, 234 | US10111875, Compound 234 | US1036...)
Affinity DataIC50: 41.1nMAssay Description:JAK1/2/3 kinase assay are performed in vitro using Kit-Tyr 6 Peptide (Invitrogen, Cat. No. PV4122). TYK2 kinase assay are performed in vitro using Z&...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2020
Entry Details
US Patent

TargetTyrosine-protein kinase JAK3(Human)
Hutchison Medipharma

US Patent
LigandChemical structure of BindingDB Monomer ID 294511BDBM294511(US10111875, Compound 206 | US10369153, Compound 20...)
Affinity DataIC50: 47nMAssay Description:JAK1/2/3 kinase assay are performed in vitro using Kit-Tyr 6 Peptide (Invitrogen, Cat. No. PV4122). TYK2 kinase assay are performed in vitro using Z&...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2020
Entry Details
US Patent

TargetTyrosine-protein kinase JAK2(Human)
Hutchison Medipharma

US Patent
LigandChemical structure of BindingDB Monomer ID 228644BDBM228644(US9346810, 105 | US10111875, Compound 105 | US1036...)
Affinity DataIC50: 48.7nMAssay Description:JAK1/2/3 kinase assay are performed in vitro using Kit-Tyr 6 Peptide (Invitrogen, Cat. No. PV4122). TYK2 kinase assay are performed in vitro using Z&...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2020
Entry Details
US Patent

TargetTyrosine-protein kinase JAK2(Human)
Hutchison Medipharma

US Patent
LigandChemical structure of BindingDB Monomer ID 228728BDBM228728(US9346810, 94 | US10111875, Compound 142 | US10369...)
Affinity DataIC50: 55nMAssay Description:JAK1/2/3 kinase assay are performed in vitro using Kit-Tyr 6 Peptide (Invitrogen, Cat. No. PV4122). TYK2 kinase assay are performed in vitro using Z&...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2020
Entry Details
US Patent

TargetTyrosine-protein kinase JAK2(Human)
Hutchison Medipharma

US Patent
LigandChemical structure of BindingDB Monomer ID 228641BDBM228641(US9346810, 199 | US10369153, Compound 199)
Affinity DataIC50: 75nMAssay Description:JAK1/2/3 kinase assay are performed in vitro using Kit-Tyr 6 Peptide (Invitrogen, Cat. No. PV4122). TYK2 kinase assay are performed in vitro using Z&...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2020
Entry Details
US Patent

TargetTyrosine-protein kinase JAK3(Human)
Hutchison Medipharma

US Patent
LigandChemical structure of BindingDB Monomer ID 228640BDBM228640(US9346810, 234 | US10111875, Compound 234 | US1036...)
Affinity DataIC50: 86.3nMAssay Description:JAK1/2/3 kinase assay are performed in vitro using Kit-Tyr 6 Peptide (Invitrogen, Cat. No. PV4122). TYK2 kinase assay are performed in vitro using Z&...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2020
Entry Details
US Patent

TargetTyrosine-protein kinase JAK2(Human)
Hutchison Medipharma

US Patent
LigandChemical structure of BindingDB Monomer ID 228645BDBM228645(US9346810, 47 | US10111875, Compound 47 | US103691...)
Affinity DataIC50: 98nMAssay Description:JAK1/2/3 kinase assay are performed in vitro using Kit-Tyr 6 Peptide (Invitrogen, Cat. No. PV4122). TYK2 kinase assay are performed in vitro using Z&...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2020
Entry Details
US Patent

TargetTyrosine-protein kinase JAK1(Human)
Hutchison Medipharma

US Patent
LigandChemical structure of BindingDB Monomer ID 228697BDBM228697(US9346810, 239 | US10369153, Compound 239)
Affinity DataIC50: 100nMAssay Description:JAK1/2/3 kinase assay are performed in vitro using Kit-Tyr 6 Peptide (Invitrogen, Cat. No. PV4122). TYK2 kinase assay are performed in vitro using Z&...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2020
Entry Details
US Patent

TargetTyrosine-protein kinase JAK1(Human)
Hutchison Medipharma

US Patent
LigandChemical structure of BindingDB Monomer ID 409811BDBM409811(US10369153, Compound 241)
Affinity DataIC50: 100nMAssay Description:JAK1/2/3 kinase assay are performed in vitro using Kit-Tyr 6 Peptide (Invitrogen, Cat. No. PV4122). TYK2 kinase assay are performed in vitro using Z&...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2020
Entry Details
US Patent

TargetTyrosine-protein kinase JAK1(Human)
Hutchison Medipharma

US Patent
LigandChemical structure of BindingDB Monomer ID 228699BDBM228699(US9346810, 242 | US10369153, Compound 242)
Affinity DataIC50: 100nMAssay Description:JAK1/2/3 kinase assay are performed in vitro using Kit-Tyr 6 Peptide (Invitrogen, Cat. No. PV4122). TYK2 kinase assay are performed in vitro using Z&...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2020
Entry Details
US Patent

TargetTyrosine-protein kinase JAK1(Human)
Hutchison Medipharma

US Patent
LigandChemical structure of BindingDB Monomer ID 228700BDBM228700(US9346810, 243 | US10369153, Compound 243)
Affinity DataIC50: 100nMAssay Description:JAK1/2/3 kinase assay are performed in vitro using Kit-Tyr 6 Peptide (Invitrogen, Cat. No. PV4122). TYK2 kinase assay are performed in vitro using Z&...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2020
Entry Details
US Patent

TargetTyrosine-protein kinase JAK1(Human)
Hutchison Medipharma

US Patent
LigandChemical structure of BindingDB Monomer ID 228640BDBM228640(US9346810, 234 | US10111875, Compound 234 | US1036...)
Affinity DataIC50: 100nMAssay Description:JAK1/2/3 kinase assay are performed in vitro using Kit-Tyr 6 Peptide (Invitrogen, Cat. No. PV4122). TYK2 kinase assay are performed in vitro using Z&...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2020
Entry Details
US Patent

TargetTyrosine-protein kinase JAK1(Human)
Hutchison Medipharma

US Patent
LigandChemical structure of BindingDB Monomer ID 228694BDBM228694(US9346810, 236 | US10369153, Compound 236)
Affinity DataIC50: 100nMAssay Description:JAK1/2/3 kinase assay are performed in vitro using Kit-Tyr 6 Peptide (Invitrogen, Cat. No. PV4122). TYK2 kinase assay are performed in vitro using Z&...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2020
Entry Details
US Patent

TargetTyrosine-protein kinase JAK1(Human)
Hutchison Medipharma

US Patent
LigandChemical structure of BindingDB Monomer ID 228695BDBM228695(US9346810, 237 | US10369153, Compound 237)
Affinity DataIC50: 100nMAssay Description:JAK1/2/3 kinase assay are performed in vitro using Kit-Tyr 6 Peptide (Invitrogen, Cat. No. PV4122). TYK2 kinase assay are performed in vitro using Z&...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2020
Entry Details
US Patent

TargetTyrosine-protein kinase JAK1(Human)
Hutchison Medipharma

US Patent
LigandChemical structure of BindingDB Monomer ID 228696BDBM228696(US9346810, 238 | US10369153, Compound 238)
Affinity DataIC50: 100nMAssay Description:JAK1/2/3 kinase assay are performed in vitro using Kit-Tyr 6 Peptide (Invitrogen, Cat. No. PV4122). TYK2 kinase assay are performed in vitro using Z&...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2020
Entry Details
US Patent

TargetTyrosine-protein kinase JAK1(Human)
Hutchison Medipharma

US Patent
LigandChemical structure of BindingDB Monomer ID 228690BDBM228690(US9346810, 217 | US10369153, Compound 217)
Affinity DataIC50: 100nMAssay Description:JAK1/2/3 kinase assay are performed in vitro using Kit-Tyr 6 Peptide (Invitrogen, Cat. No. PV4122). TYK2 kinase assay are performed in vitro using Z&...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2020
Entry Details
US Patent

TargetTyrosine-protein kinase JAK1(Human)
Hutchison Medipharma

US Patent
LigandChemical structure of BindingDB Monomer ID 228691BDBM228691(US9346810, 218 | US10369153, Compound 218)
Affinity DataIC50: 100nMAssay Description:JAK1/2/3 kinase assay are performed in vitro using Kit-Tyr 6 Peptide (Invitrogen, Cat. No. PV4122). TYK2 kinase assay are performed in vitro using Z&...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2020
Entry Details
US Patent

TargetTyrosine-protein kinase JAK1(Human)
Hutchison Medipharma

US Patent
LigandChemical structure of BindingDB Monomer ID 228692BDBM228692(US9346810, 219 | US10369153, Compound 219)
Affinity DataIC50: 100nMAssay Description:JAK1/2/3 kinase assay are performed in vitro using Kit-Tyr 6 Peptide (Invitrogen, Cat. No. PV4122). TYK2 kinase assay are performed in vitro using Z&...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2020
Entry Details
US Patent

TargetTyrosine-protein kinase JAK1(Human)
Hutchison Medipharma

US Patent
LigandChemical structure of BindingDB Monomer ID 228693BDBM228693(US9346810, 233 | US10369153, Compound 233)
Affinity DataIC50: 100nMAssay Description:JAK1/2/3 kinase assay are performed in vitro using Kit-Tyr 6 Peptide (Invitrogen, Cat. No. PV4122). TYK2 kinase assay are performed in vitro using Z&...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2020
Entry Details
US Patent

TargetTyrosine-protein kinase JAK1(Human)
Hutchison Medipharma

US Patent
LigandChemical structure of BindingDB Monomer ID 409798BDBM409798(US10369153, Compound 161)
Affinity DataIC50: 100nMAssay Description:JAK1/2/3 kinase assay are performed in vitro using Kit-Tyr 6 Peptide (Invitrogen, Cat. No. PV4122). TYK2 kinase assay are performed in vitro using Z&...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2020
Entry Details
US Patent

TargetTyrosine-protein kinase JAK1(Human)
Hutchison Medipharma

US Patent
LigandChemical structure of BindingDB Monomer ID 228687BDBM228687(US9346810, 202 | US10369153, Compound 202)
Affinity DataIC50: 100nMAssay Description:JAK1/2/3 kinase assay are performed in vitro using Kit-Tyr 6 Peptide (Invitrogen, Cat. No. PV4122). TYK2 kinase assay are performed in vitro using Z&...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2020
Entry Details
US Patent

TargetTyrosine-protein kinase JAK1(Human)
Hutchison Medipharma

US Patent
LigandChemical structure of BindingDB Monomer ID 409800BDBM409800(US10369153, Compound 214)
Affinity DataIC50: 100nMAssay Description:JAK1/2/3 kinase assay are performed in vitro using Kit-Tyr 6 Peptide (Invitrogen, Cat. No. PV4122). TYK2 kinase assay are performed in vitro using Z&...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2020
Entry Details
US Patent

TargetTyrosine-protein kinase JAK1(Human)
Hutchison Medipharma

US Patent
LigandChemical structure of BindingDB Monomer ID 228689BDBM228689(US9346810, 215 | US10369153, Compound 215)
Affinity DataIC50: 100nMAssay Description:JAK1/2/3 kinase assay are performed in vitro using Kit-Tyr 6 Peptide (Invitrogen, Cat. No. PV4122). TYK2 kinase assay are performed in vitro using Z&...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2020
Entry Details
US Patent

TargetTyrosine-protein kinase JAK2(Human)
Hutchison Medipharma

US Patent
LigandChemical structure of BindingDB Monomer ID 409824BDBM409824(US10369153, Compound 46)
Affinity DataIC50: 100nMAssay Description:JAK1/2/3 kinase assay are performed in vitro using Kit-Tyr 6 Peptide (Invitrogen, Cat. No. PV4122). TYK2 kinase assay are performed in vitro using Z&...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2020
Entry Details
US Patent

TargetTyrosine-protein kinase JAK2(Human)
Hutchison Medipharma

US Patent
LigandChemical structure of BindingDB Monomer ID 228645BDBM228645(US9346810, 47 | US10111875, Compound 47 | US103691...)
Affinity DataIC50: 100nMAssay Description:JAK1/2/3 kinase assay are performed in vitro using Kit-Tyr 6 Peptide (Invitrogen, Cat. No. PV4122). TYK2 kinase assay are performed in vitro using Z&...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2020
Entry Details
US Patent

TargetTyrosine-protein kinase JAK2(Human)
Hutchison Medipharma

US Patent
LigandChemical structure of BindingDB Monomer ID 228712BDBM228712(US9346810, 48 | US10369153, Compound 48)
Affinity DataIC50: 100nMAssay Description:JAK1/2/3 kinase assay are performed in vitro using Kit-Tyr 6 Peptide (Invitrogen, Cat. No. PV4122). TYK2 kinase assay are performed in vitro using Z&...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2020
Entry Details
US Patent

TargetTyrosine-protein kinase JAK2(Human)
Hutchison Medipharma

US Patent
LigandChemical structure of BindingDB Monomer ID 228713BDBM228713(US9346810, 60 | US10369153, Compound 60)
Affinity DataIC50: 100nMAssay Description:JAK1/2/3 kinase assay are performed in vitro using Kit-Tyr 6 Peptide (Invitrogen, Cat. No. PV4122). TYK2 kinase assay are performed in vitro using Z&...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2020
Entry Details
US Patent

TargetTyrosine-protein kinase JAK2(Human)
Hutchison Medipharma

US Patent
LigandChemical structure of BindingDB Monomer ID 228661BDBM228661(US9346810, 1 | US10369153, Compound 1)
Affinity DataIC50: 100nMAssay Description:JAK1/2/3 kinase assay are performed in vitro using Kit-Tyr 6 Peptide (Invitrogen, Cat. No. PV4122). TYK2 kinase assay are performed in vitro using Z&...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2020
Entry Details
US Patent

TargetTyrosine-protein kinase JAK2(Human)
Hutchison Medipharma

US Patent
LigandChemical structure of BindingDB Monomer ID 228709BDBM228709(US9346810, 40 | US10369153, Compound 40)
Affinity DataIC50: 100nMAssay Description:JAK1/2/3 kinase assay are performed in vitro using Kit-Tyr 6 Peptide (Invitrogen, Cat. No. PV4122). TYK2 kinase assay are performed in vitro using Z&...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2020
Entry Details
US Patent

TargetTyrosine-protein kinase JAK2(Human)
Hutchison Medipharma

US Patent
LigandChemical structure of BindingDB Monomer ID 228710BDBM228710(US9346810, 41 | US10369153, Compound 41)
Affinity DataIC50: 100nMAssay Description:JAK1/2/3 kinase assay are performed in vitro using Kit-Tyr 6 Peptide (Invitrogen, Cat. No. PV4122). TYK2 kinase assay are performed in vitro using Z&...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2020
Entry Details
US Patent

TargetTyrosine-protein kinase JAK2(Human)
Hutchison Medipharma

US Patent
LigandChemical structure of BindingDB Monomer ID 228668BDBM228668(US9346810, 42 | US10369153, Compound 42)
Affinity DataIC50: 100nMAssay Description:JAK1/2/3 kinase assay are performed in vitro using Kit-Tyr 6 Peptide (Invitrogen, Cat. No. PV4122). TYK2 kinase assay are performed in vitro using Z&...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2020
Entry Details
US Patent

TargetTyrosine-protein kinase JAK1(Human)
Hutchison Medipharma

US Patent
LigandChemical structure of BindingDB Monomer ID 228705BDBM228705(US9346810, 252 | US10369153, Compound 252)
Affinity DataIC50: 100nMAssay Description:JAK1/2/3 kinase assay are performed in vitro using Kit-Tyr 6 Peptide (Invitrogen, Cat. No. PV4122). TYK2 kinase assay are performed in vitro using Z&...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2020
Entry Details
US Patent

TargetTyrosine-protein kinase JAK1(Human)
Hutchison Medipharma

US Patent
LigandChemical structure of BindingDB Monomer ID 228706BDBM228706(US9346810, 253 | US10369153, Compound 253)
Affinity DataIC50: 100nMAssay Description:JAK1/2/3 kinase assay are performed in vitro using Kit-Tyr 6 Peptide (Invitrogen, Cat. No. PV4122). TYK2 kinase assay are performed in vitro using Z&...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2020
Entry Details
US Patent

TargetTyrosine-protein kinase JAK1(Human)
Hutchison Medipharma

US Patent
LigandChemical structure of BindingDB Monomer ID 228707BDBM228707(US9346810, 254 | US10369153, Compound 254)
Affinity DataIC50: 100nMAssay Description:JAK1/2/3 kinase assay are performed in vitro using Kit-Tyr 6 Peptide (Invitrogen, Cat. No. PV4122). TYK2 kinase assay are performed in vitro using Z&...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2020
Entry Details
US Patent

TargetTyrosine-protein kinase JAK1(Human)
Hutchison Medipharma

US Patent
LigandChemical structure of BindingDB Monomer ID 228708BDBM228708(US9346810, 259 | US10369153, Compound 259)
Affinity DataIC50: 100nMAssay Description:JAK1/2/3 kinase assay are performed in vitro using Kit-Tyr 6 Peptide (Invitrogen, Cat. No. PV4122). TYK2 kinase assay are performed in vitro using Z&...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2020
Entry Details
US Patent

TargetTyrosine-protein kinase JAK1(Human)
Hutchison Medipharma

US Patent
LigandChemical structure of BindingDB Monomer ID 228701BDBM228701(US9346810, 245 | US10369153, Compound 245)
Affinity DataIC50: 100nMAssay Description:JAK1/2/3 kinase assay are performed in vitro using Kit-Tyr 6 Peptide (Invitrogen, Cat. No. PV4122). TYK2 kinase assay are performed in vitro using Z&...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2020
Entry Details
US Patent

TargetTyrosine-protein kinase JAK1(Human)
Hutchison Medipharma

US Patent
LigandChemical structure of BindingDB Monomer ID 228702BDBM228702(US9346810, 246 | US10369153, Compound 246)
Affinity DataIC50: 100nMAssay Description:JAK1/2/3 kinase assay are performed in vitro using Kit-Tyr 6 Peptide (Invitrogen, Cat. No. PV4122). TYK2 kinase assay are performed in vitro using Z&...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2020
Entry Details
US Patent

TargetTyrosine-protein kinase JAK1(Human)
Hutchison Medipharma

US Patent
LigandChemical structure of BindingDB Monomer ID 228703BDBM228703(US9346810, 247 | US10369153, Compound 247)
Affinity DataIC50: 100nMAssay Description:JAK1/2/3 kinase assay are performed in vitro using Kit-Tyr 6 Peptide (Invitrogen, Cat. No. PV4122). TYK2 kinase assay are performed in vitro using Z&...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2020
Entry Details
US Patent

TargetTyrosine-protein kinase JAK1(Human)
Hutchison Medipharma

US Patent
LigandChemical structure of BindingDB Monomer ID 228704BDBM228704(US9346810, 251 | US10369153, Compound 251)
Affinity DataIC50: 100nMAssay Description:JAK1/2/3 kinase assay are performed in vitro using Kit-Tyr 6 Peptide (Invitrogen, Cat. No. PV4122). TYK2 kinase assay are performed in vitro using Z&...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2020
Entry Details
US Patent

TargetTyrosine-protein kinase JAK2(Human)
Hutchison Medipharma

US Patent
LigandChemical structure of BindingDB Monomer ID 228724BDBM228724(US9346810, 87 | US10369153, Compound 87)
Affinity DataIC50: 100nMAssay Description:JAK1/2/3 kinase assay are performed in vitro using Kit-Tyr 6 Peptide (Invitrogen, Cat. No. PV4122). TYK2 kinase assay are performed in vitro using Z&...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2020
Entry Details
US Patent

TargetTyrosine-protein kinase JAK2(Human)
Hutchison Medipharma

US Patent
LigandChemical structure of BindingDB Monomer ID 228725BDBM228725(US9346810, 91 | US10369153, Compound 91)
Affinity DataIC50: 100nMAssay Description:JAK1/2/3 kinase assay are performed in vitro using Kit-Tyr 6 Peptide (Invitrogen, Cat. No. PV4122). TYK2 kinase assay are performed in vitro using Z&...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2020
Entry Details
US Patent

TargetTyrosine-protein kinase JAK2(Human)
Hutchison Medipharma

US Patent
LigandChemical structure of BindingDB Monomer ID 409840BDBM409840(US10369153, Compound 92)
Affinity DataIC50: 100nMAssay Description:JAK1/2/3 kinase assay are performed in vitro using Kit-Tyr 6 Peptide (Invitrogen, Cat. No. PV4122). TYK2 kinase assay are performed in vitro using Z&...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2020
Entry Details
US Patent

TargetTyrosine-protein kinase JAK2(Human)
Hutchison Medipharma

US Patent
LigandChemical structure of BindingDB Monomer ID 409841BDBM409841(US10369153, Compound 93)
Affinity DataIC50: 100nMAssay Description:JAK1/2/3 kinase assay are performed in vitro using Kit-Tyr 6 Peptide (Invitrogen, Cat. No. PV4122). TYK2 kinase assay are performed in vitro using Z&...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2020
Entry Details
US Patent

TargetTyrosine-protein kinase JAK2(Human)
Hutchison Medipharma

US Patent
LigandChemical structure of BindingDB Monomer ID 228721BDBM228721(US9346810, 80 | US10369153, Compound 80)
Affinity DataIC50: 100nMAssay Description:JAK1/2/3 kinase assay are performed in vitro using Kit-Tyr 6 Peptide (Invitrogen, Cat. No. PV4122). TYK2 kinase assay are performed in vitro using Z&...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2020
Entry Details
US Patent

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