Compile Data Set for Download or QSAR
Report error Found 50 Enz. Inhib. hit(s) with all data for entry = 8638
TargetToll-like receptor 8(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 409973BDBM409973(2-Amino-8-(3-anilinopyrrolidine-1-carbonyl)-N,N-di...)
Affinity DataEC50:  4nMAssay Description:For TLR8 and TLR7 activity testing, HEK-Blue human TLR8 or TLR7 cells (Invivogen, San Diego, Calif., USA) are used, respectively. These cells are des...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2020
Entry Details
US Patent

TargetToll-like receptor 8(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 409979BDBM409979(2-Amino-8-(3-benzyloxyazetidine-1-carbonyl)-N,N-di...)
Affinity DataEC50:  4nMAssay Description:For TLR8 and TLR7 activity testing, HEK-Blue human TLR8 or TLR7 cells (Invivogen, San Diego, Calif., USA) are used, respectively. These cells are des...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2020
Entry Details
US Patent

TargetToll-like receptor 8(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 409978BDBM409978(2-Amino-8-(4-benzylpiperazine-1-carbonyl)-N,N-dipr...)
Affinity DataEC50:  5nMAssay Description:For TLR8 and TLR7 activity testing, HEK-Blue human TLR8 or TLR7 cells (Invivogen, San Diego, Calif., USA) are used, respectively. These cells are des...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2020
Entry Details
US Patent

TargetToll-like receptor 8(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 409971BDBM409971(2-Amino-8-(3-anilinoazetidine-1-carbonyl)-N,N-dipr...)
Affinity DataEC50:  5nMAssay Description:For TLR8 and TLR7 activity testing, HEK-Blue human TLR8 or TLR7 cells (Invivogen, San Diego, Calif., USA) are used, respectively. These cells are des...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2020
Entry Details
US Patent

TargetToll-like receptor 8(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 409969BDBM409969(2-Amino-N,N-dipropyl-8-[6-(p-tolyl)-2,6-diazaspiro...)
Affinity DataEC50:  5nMAssay Description:For TLR8 and TLR7 activity testing, HEK-Blue human TLR8 or TLR7 cells (Invivogen, San Diego, Calif., USA) are used, respectively. These cells are des...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2020
Entry Details
US Patent

TargetToll-like receptor 8(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 409970BDBM409970(2-Amino-8-(4-anilinopiperidine-1-carbonyl)-N,N-dip...)
Affinity DataEC50:  6nMAssay Description:For TLR8 and TLR7 activity testing, HEK-Blue human TLR8 or TLR7 cells (Invivogen, San Diego, Calif., USA) are used, respectively. These cells are des...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2020
Entry Details
US Patent

TargetToll-like receptor 8(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 409981BDBM409981(2-Amino-8-(2-phenyl-2,7-diazaspiro[3.5]nonane-7-ca...)
Affinity DataEC50:  7nMAssay Description:For TLR8 and TLR7 activity testing, HEK-Blue human TLR8 or TLR7 cells (Invivogen, San Diego, Calif., USA) are used, respectively. These cells are des...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2020
Entry Details
US Patent

TargetToll-like receptor 8(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 409991BDBM409991(2-Amino-8-(3-anilinopiperidine-1-carbonyl)-N,N-dip...)
Affinity DataEC50:  8nMAssay Description:For TLR8 and TLR7 activity testing, HEK-Blue human TLR8 or TLR7 cells (Invivogen, San Diego, Calif., USA) are used, respectively. These cells are des...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2020
Entry Details
US Patent

TargetToll-like receptor 8(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 409993BDBM409993(2-Amino-8-(3-butoxyazetidine-1-carbonyl)-N,N-dipro...)
Affinity DataEC50:  8nMAssay Description:For TLR8 and TLR7 activity testing, HEK-Blue human TLR8 or TLR7 cells (Invivogen, San Diego, Calif., USA) are used, respectively. These cells are des...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2020
Entry Details
US Patent

TargetToll-like receptor 8(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 409982BDBM409982(2-Amino-8-(7-phenyl-2,7-diazaspiro[3.5]nonane-2-ca...)
Affinity DataEC50:  9nMAssay Description:For TLR8 and TLR7 activity testing, HEK-Blue human TLR8 or TLR7 cells (Invivogen, San Diego, Calif., USA) are used, respectively. These cells are des...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2020
Entry Details
US Patent

TargetToll-like receptor 8(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 409989BDBM409989(2-Amino-8-[3-(anilinomethyl)pyrrolidine-1-carbonyl...)
Affinity DataEC50:  9nMAssay Description:For TLR8 and TLR7 activity testing, HEK-Blue human TLR8 or TLR7 cells (Invivogen, San Diego, Calif., USA) are used, respectively. These cells are des...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2020
Entry Details
US Patent

TargetToll-like receptor 8(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 409975BDBM409975(2-Amino-8-(7-phenyl-2,7-diazaspiro[3.4]octane-2-ca...)
Affinity DataEC50:  10nMAssay Description:For TLR8 and TLR7 activity testing, HEK-Blue human TLR8 or TLR7 cells (Invivogen, San Diego, Calif., USA) are used, respectively. These cells are des...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2020
Entry Details
US Patent

TargetToll-like receptor 8(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 409983BDBM409983(2-Amino-8-(8-phenyl-3,8-diazabicyclo[3.2.1]octane-...)
Affinity DataEC50:  10nMAssay Description:For TLR8 and TLR7 activity testing, HEK-Blue human TLR8 or TLR7 cells (Invivogen, San Diego, Calif., USA) are used, respectively. These cells are des...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2020
Entry Details
US Patent

TargetToll-like receptor 8(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 409972BDBM409972(2-Amino-8-[3-(anilinomethyl)azetidine-1-carbonyl]-...)
Affinity DataEC50:  10nMAssay Description:For TLR8 and TLR7 activity testing, HEK-Blue human TLR8 or TLR7 cells (Invivogen, San Diego, Calif., USA) are used, respectively. These cells are des...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2020
Entry Details
US Patent

TargetToll-like receptor 8(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 409990BDBM409990(2-Amino-8-[3-[(E)-but-2-enoxy]azetidine-1-carbonyl...)
Affinity DataEC50:  12nMAssay Description:For TLR8 and TLR7 activity testing, HEK-Blue human TLR8 or TLR7 cells (Invivogen, San Diego, Calif., USA) are used, respectively. These cells are des...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2020
Entry Details
US Patent

TargetToll-like receptor 8(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 409987BDBM409987(2-Amino-8-[3-(benzylamino)pyrrolidine-1-carbonyl]-...)
Affinity DataEC50:  14nMAssay Description:For TLR8 and TLR7 activity testing, HEK-Blue human TLR8 or TLR7 cells (Invivogen, San Diego, Calif., USA) are used, respectively. These cells are des...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2020
Entry Details
US Patent

TargetToll-like receptor 8(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 409992BDBM409992(2-Amino-8-[3-(benzylamino)piperidine-1-carbonyl]-N...)
Affinity DataEC50:  14nMAssay Description:For TLR8 and TLR7 activity testing, HEK-Blue human TLR8 or TLR7 cells (Invivogen, San Diego, Calif., USA) are used, respectively. These cells are des...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2020
Entry Details
US Patent

TargetToll-like receptor 8(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 409976BDBM409976(2-Amino-N,N-dipropyl-8-(pyrrolidine-1-carbonyl)-3H...)
Affinity DataEC50:  15nMAssay Description:For TLR8 and TLR7 activity testing, HEK-Blue human TLR8 or TLR7 cells (Invivogen, San Diego, Calif., USA) are used, respectively. These cells are des...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2020
Entry Details
US Patent

TargetToll-like receptor 8(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 409985BDBM409985(2-Amino-8-[3-(benzylamino)azetidine-1-carbonyl]-N,...)
Affinity DataEC50:  18nMAssay Description:For TLR8 and TLR7 activity testing, HEK-Blue human TLR8 or TLR7 cells (Invivogen, San Diego, Calif., USA) are used, respectively. These cells are des...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2020
Entry Details
US Patent

TargetToll-like receptor 8(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 409988BDBM409988(2-amino-8-[4-(anilinomethyl)piperidine-1-carbonyl]...)
Affinity DataEC50:  20nMAssay Description:For TLR8 and TLR7 activity testing, HEK-Blue human TLR8 or TLR7 cells (Invivogen, San Diego, Calif., USA) are used, respectively. These cells are des...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2020
Entry Details
US Patent

TargetToll-like receptor 8(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 409977BDBM409977(2-Amino-8-(4-anilinopiperidine-1-carbonyl)-N-(cycl...)
Affinity DataEC50:  20nMAssay Description:For TLR8 and TLR7 activity testing, HEK-Blue human TLR8 or TLR7 cells (Invivogen, San Diego, Calif., USA) are used, respectively. These cells are des...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2020
Entry Details
US Patent

TargetToll-like receptor 8(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 409980BDBM409980(2-Amino-8-(6-phenyl-3,6-diazabicyclo[3.1.1]heptane...)
Affinity DataEC50:  22nMAssay Description:For TLR8 and TLR7 activity testing, HEK-Blue human TLR8 or TLR7 cells (Invivogen, San Diego, Calif., USA) are used, respectively. These cells are des...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2020
Entry Details
US Patent

TargetToll-like receptor 8(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 409974BDBM409974(2-Amino-8-(4-phenylpiperazine-1-carbonyl)-N,N-dipr...)
Affinity DataEC50:  25nMAssay Description:For TLR8 and TLR7 activity testing, HEK-Blue human TLR8 or TLR7 cells (Invivogen, San Diego, Calif., USA) are used, respectively. These cells are des...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2020
Entry Details
US Patent

TargetToll-like receptor 8(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 409984BDBM409984(2-Amino-8-(6-phenyl-3,6-diazabicyclo[3.2.0]heptane...)
Affinity DataEC50:  29nMAssay Description:For TLR8 and TLR7 activity testing, HEK-Blue human TLR8 or TLR7 cells (Invivogen, San Diego, Calif., USA) are used, respectively. These cells are des...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2020
Entry Details
US Patent

TargetToll-like receptor 8(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 409986BDBM409986(2-Amino-8-[3-[4-(aminomethyl)anilino]pyrrolidine-1...)
Affinity DataEC50:  31nMAssay Description:For TLR8 and TLR7 activity testing, HEK-Blue human TLR8 or TLR7 cells (Invivogen, San Diego, Calif., USA) are used, respectively. These cells are des...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2020
Entry Details
US Patent

TargetToll-like receptor 7(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 409991BDBM409991(2-Amino-8-(3-anilinopiperidine-1-carbonyl)-N,N-dip...)
Affinity DataEC50:  400nMAssay Description:For TLR8 and TLR7 activity testing, HEK-Blue human TLR8 or TLR7 cells (Invivogen, San Diego, Calif., USA) are used, respectively. These cells are des...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2020
Entry Details
US Patent

TargetToll-like receptor 7(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 409992BDBM409992(2-Amino-8-[3-(benzylamino)piperidine-1-carbonyl]-N...)
Affinity DataEC50:  3.10E+3nMAssay Description:For TLR8 and TLR7 activity testing, HEK-Blue human TLR8 or TLR7 cells (Invivogen, San Diego, Calif., USA) are used, respectively. These cells are des...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2020
Entry Details
US Patent

TargetToll-like receptor 7(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 409987BDBM409987(2-Amino-8-[3-(benzylamino)pyrrolidine-1-carbonyl]-...)
Affinity DataEC50:  6.60E+3nMAssay Description:For TLR8 and TLR7 activity testing, HEK-Blue human TLR8 or TLR7 cells (Invivogen, San Diego, Calif., USA) are used, respectively. These cells are des...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2020
Entry Details
US Patent

TargetToll-like receptor 7(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 409989BDBM409989(2-Amino-8-[3-(anilinomethyl)pyrrolidine-1-carbonyl...)
Affinity DataEC50:  6.98E+3nMAssay Description:For TLR8 and TLR7 activity testing, HEK-Blue human TLR8 or TLR7 cells (Invivogen, San Diego, Calif., USA) are used, respectively. These cells are des...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2020
Entry Details
US Patent

TargetToll-like receptor 7(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 409970BDBM409970(2-Amino-8-(4-anilinopiperidine-1-carbonyl)-N,N-dip...)
Affinity DataEC50:  7.90E+3nMAssay Description:For TLR8 and TLR7 activity testing, HEK-Blue human TLR8 or TLR7 cells (Invivogen, San Diego, Calif., USA) are used, respectively. These cells are des...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2020
Entry Details
US Patent

TargetToll-like receptor 7(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 409974BDBM409974(2-Amino-8-(4-phenylpiperazine-1-carbonyl)-N,N-dipr...)
Affinity DataEC50:  9.00E+3nMAssay Description:For TLR8 and TLR7 activity testing, HEK-Blue human TLR8 or TLR7 cells (Invivogen, San Diego, Calif., USA) are used, respectively. These cells are des...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2020
Entry Details
US Patent

TargetToll-like receptor 7(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 409972BDBM409972(2-Amino-8-[3-(anilinomethyl)azetidine-1-carbonyl]-...)
Affinity DataEC50:  1.00E+4nMAssay Description:For TLR8 and TLR7 activity testing, HEK-Blue human TLR8 or TLR7 cells (Invivogen, San Diego, Calif., USA) are used, respectively. These cells are des...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2020
Entry Details
US Patent

TargetToll-like receptor 7(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 409988BDBM409988(2-amino-8-[4-(anilinomethyl)piperidine-1-carbonyl]...)
Affinity DataEC50:  1.00E+4nMAssay Description:For TLR8 and TLR7 activity testing, HEK-Blue human TLR8 or TLR7 cells (Invivogen, San Diego, Calif., USA) are used, respectively. These cells are des...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2020
Entry Details
US Patent

TargetToll-like receptor 7(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 409980BDBM409980(2-Amino-8-(6-phenyl-3,6-diazabicyclo[3.1.1]heptane...)
Affinity DataEC50:  1.10E+4nMAssay Description:For TLR8 and TLR7 activity testing, HEK-Blue human TLR8 or TLR7 cells (Invivogen, San Diego, Calif., USA) are used, respectively. These cells are des...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2020
Entry Details
US Patent

TargetToll-like receptor 7(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 409984BDBM409984(2-Amino-8-(6-phenyl-3,6-diazabicyclo[3.2.0]heptane...)
Affinity DataEC50:  1.20E+4nMAssay Description:For TLR8 and TLR7 activity testing, HEK-Blue human TLR8 or TLR7 cells (Invivogen, San Diego, Calif., USA) are used, respectively. These cells are des...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2020
Entry Details
US Patent

TargetToll-like receptor 7(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 409973BDBM409973(2-Amino-8-(3-anilinopyrrolidine-1-carbonyl)-N,N-di...)
Affinity DataEC50:  1.40E+4nMAssay Description:For TLR8 and TLR7 activity testing, HEK-Blue human TLR8 or TLR7 cells (Invivogen, San Diego, Calif., USA) are used, respectively. These cells are des...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2020
Entry Details
US Patent

TargetToll-like receptor 7(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 409978BDBM409978(2-Amino-8-(4-benzylpiperazine-1-carbonyl)-N,N-dipr...)
Affinity DataEC50:  1.40E+4nMAssay Description:For TLR8 and TLR7 activity testing, HEK-Blue human TLR8 or TLR7 cells (Invivogen, San Diego, Calif., USA) are used, respectively. These cells are des...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2020
Entry Details
US Patent

TargetToll-like receptor 7(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 409979BDBM409979(2-Amino-8-(3-benzyloxyazetidine-1-carbonyl)-N,N-di...)
Affinity DataEC50:  1.50E+4nMAssay Description:For TLR8 and TLR7 activity testing, HEK-Blue human TLR8 or TLR7 cells (Invivogen, San Diego, Calif., USA) are used, respectively. These cells are des...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2020
Entry Details
US Patent

TargetToll-like receptor 7(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 409983BDBM409983(2-Amino-8-(8-phenyl-3,8-diazabicyclo[3.2.1]octane-...)
Affinity DataEC50:  1.60E+4nMAssay Description:For TLR8 and TLR7 activity testing, HEK-Blue human TLR8 or TLR7 cells (Invivogen, San Diego, Calif., USA) are used, respectively. These cells are des...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2020
Entry Details
US Patent

TargetToll-like receptor 7(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 409985BDBM409985(2-Amino-8-[3-(benzylamino)azetidine-1-carbonyl]-N,...)
Affinity DataEC50:  1.70E+4nMAssay Description:For TLR8 and TLR7 activity testing, HEK-Blue human TLR8 or TLR7 cells (Invivogen, San Diego, Calif., USA) are used, respectively. These cells are des...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2020
Entry Details
US Patent

TargetToll-like receptor 7(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 409977BDBM409977(2-Amino-8-(4-anilinopiperidine-1-carbonyl)-N-(cycl...)
Affinity DataEC50:  1.80E+4nMAssay Description:For TLR8 and TLR7 activity testing, HEK-Blue human TLR8 or TLR7 cells (Invivogen, San Diego, Calif., USA) are used, respectively. These cells are des...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2020
Entry Details
US Patent

TargetToll-like receptor 7(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 409976BDBM409976(2-Amino-N,N-dipropyl-8-(pyrrolidine-1-carbonyl)-3H...)
Affinity DataEC50:  2.10E+4nMAssay Description:For TLR8 and TLR7 activity testing, HEK-Blue human TLR8 or TLR7 cells (Invivogen, San Diego, Calif., USA) are used, respectively. These cells are des...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2020
Entry Details
US Patent

TargetToll-like receptor 7(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 409971BDBM409971(2-Amino-8-(3-anilinoazetidine-1-carbonyl)-N,N-dipr...)
Affinity DataEC50:  2.40E+4nMAssay Description:For TLR8 and TLR7 activity testing, HEK-Blue human TLR8 or TLR7 cells (Invivogen, San Diego, Calif., USA) are used, respectively. These cells are des...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2020
Entry Details
US Patent

TargetToll-like receptor 7(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 409993BDBM409993(2-Amino-8-(3-butoxyazetidine-1-carbonyl)-N,N-dipro...)
Affinity DataEC50:  3.11E+4nMAssay Description:For TLR8 and TLR7 activity testing, HEK-Blue human TLR8 or TLR7 cells (Invivogen, San Diego, Calif., USA) are used, respectively. These cells are des...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2020
Entry Details
US Patent

TargetToll-like receptor 7(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 409990BDBM409990(2-Amino-8-[3-[(E)-but-2-enoxy]azetidine-1-carbonyl...)
Affinity DataEC50:  3.20E+4nMAssay Description:For TLR8 and TLR7 activity testing, HEK-Blue human TLR8 or TLR7 cells (Invivogen, San Diego, Calif., USA) are used, respectively. These cells are des...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2020
Entry Details
US Patent

TargetToll-like receptor 7(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 409982BDBM409982(2-Amino-8-(7-phenyl-2,7-diazaspiro[3.5]nonane-2-ca...)
Affinity DataEC50:  3.30E+4nMAssay Description:For TLR8 and TLR7 activity testing, HEK-Blue human TLR8 or TLR7 cells (Invivogen, San Diego, Calif., USA) are used, respectively. These cells are des...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2020
Entry Details
US Patent

TargetToll-like receptor 7(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 409981BDBM409981(2-Amino-8-(2-phenyl-2,7-diazaspiro[3.5]nonane-7-ca...)
Affinity DataEC50: >1.00E+5nMAssay Description:For TLR8 and TLR7 activity testing, HEK-Blue human TLR8 or TLR7 cells (Invivogen, San Diego, Calif., USA) are used, respectively. These cells are des...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2020
Entry Details
US Patent

TargetToll-like receptor 7(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 409969BDBM409969(2-Amino-N,N-dipropyl-8-[6-(p-tolyl)-2,6-diazaspiro...)
Affinity DataEC50: >1.00E+5nMAssay Description:For TLR8 and TLR7 activity testing, HEK-Blue human TLR8 or TLR7 cells (Invivogen, San Diego, Calif., USA) are used, respectively. These cells are des...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2020
Entry Details
US Patent

TargetToll-like receptor 7(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 409986BDBM409986(2-Amino-8-[3-[4-(aminomethyl)anilino]pyrrolidine-1...)
Affinity DataEC50: >1.00E+5nMAssay Description:For TLR8 and TLR7 activity testing, HEK-Blue human TLR8 or TLR7 cells (Invivogen, San Diego, Calif., USA) are used, respectively. These cells are des...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2020
Entry Details
US Patent

TargetToll-like receptor 7(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 409975BDBM409975(2-Amino-8-(7-phenyl-2,7-diazaspiro[3.4]octane-2-ca...)
Affinity DataEC50: >1.00E+5nMAssay Description:For TLR8 and TLR7 activity testing, HEK-Blue human TLR8 or TLR7 cells (Invivogen, San Diego, Calif., USA) are used, respectively. These cells are des...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2020
Entry Details
US Patent