Compile Data Set for Download or QSAR
Report error Found 196 Enz. Inhib. hit(s) with all data for entry = 8646
TargetTyrosine-protein kinase JAK1 [837-1142](Human)
Incyte Holdings

US Patent
LigandChemical structure of BindingDB Monomer ID 344033BDBM344033(US9777017, Example 17 | US9908895, Example 17 | US...)
Affinity DataIC50: 100nMAssay Description:Compounds herein were tested for inhibitory activity of JAK targets according to the following in vitro assay described in Park et al., Analytical Bi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2020
Entry Details
US Patent

TargetTyrosine-protein kinase JAK1 [837-1142](Human)
Incyte Holdings

US Patent
LigandChemical structure of BindingDB Monomer ID 344091BDBM344091(US9777017, Example 75 | US9908895, Example 75 | US...)
Affinity DataIC50: 100nMAssay Description:Compounds herein were tested for inhibitory activity of JAK targets according to the following in vitro assay described in Park et al., Analytical Bi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2020
Entry Details
US Patent

TargetTyrosine-protein kinase JAK1 [837-1142](Human)
Incyte Holdings

US Patent
LigandChemical structure of BindingDB Monomer ID 344088BDBM344088(US9777017, Example 72 | US9908895, Example 72 | US...)
Affinity DataIC50: 100nMAssay Description:Compounds herein were tested for inhibitory activity of JAK targets according to the following in vitro assay described in Park et al., Analytical Bi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2020
Entry Details
US Patent

TargetTyrosine-protein kinase JAK1 [837-1142](Human)
Incyte Holdings

US Patent
LigandChemical structure of BindingDB Monomer ID 344089BDBM344089(US9777017, Example 73 | US9908895, Example 73 | US...)
Affinity DataIC50: 100nMAssay Description:Compounds herein were tested for inhibitory activity of JAK targets according to the following in vitro assay described in Park et al., Analytical Bi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2020
Entry Details
US Patent

TargetTyrosine-protein kinase JAK1 [837-1142](Human)
Incyte Holdings

US Patent
LigandChemical structure of BindingDB Monomer ID 344028BDBM344028(US9777017, Example 12 | US9908895, Example 12 | US...)
Affinity DataIC50: 100nMAssay Description:Compounds herein were tested for inhibitory activity of JAK targets according to the following in vitro assay described in Park et al., Analytical Bi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2020
Entry Details
US Patent

TargetTyrosine-protein kinase JAK1 [837-1142](Human)
Incyte Holdings

US Patent
LigandChemical structure of BindingDB Monomer ID 344029BDBM344029(US9777017, Example 13 | US9908895, Example 13 | US...)
Affinity DataIC50: 100nMAssay Description:Compounds herein were tested for inhibitory activity of JAK targets according to the following in vitro assay described in Park et al., Analytical Bi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2020
Entry Details
US Patent

TargetTyrosine-protein kinase JAK1 [837-1142](Human)
Incyte Holdings

US Patent
LigandChemical structure of BindingDB Monomer ID 344087BDBM344087(US9777017, Example 71 | US9908895, Example 71 | US...)
Affinity DataIC50: 100nMAssay Description:Compounds herein were tested for inhibitory activity of JAK targets according to the following in vitro assay described in Park et al., Analytical Bi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2020
Entry Details
US Patent

TargetTyrosine-protein kinase JAK1 [837-1142](Human)
Incyte Holdings

US Patent
LigandChemical structure of BindingDB Monomer ID 344018BDBM344018(US9777017, Example 10 | US9777017, Example 2 | US9...)
Affinity DataIC50: 100nMAssay Description:Compounds herein were tested for inhibitory activity of JAK targets according to the following in vitro assay described in Park et al., Analytical Bi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2020
Entry Details
US Patent

TargetTyrosine-protein kinase JAK1 [837-1142](Human)
Incyte Holdings

US Patent
LigandChemical structure of BindingDB Monomer ID 344084BDBM344084(US9777017, Example 68 | US10370387, Example 68 | U...)
Affinity DataIC50: 100nMAssay Description:Compounds herein were tested for inhibitory activity of JAK targets according to the following in vitro assay described in Park et al., Analytical Bi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2020
Entry Details
US Patent

TargetTyrosine-protein kinase JAK1 [837-1142](Human)
Incyte Holdings

US Patent
LigandChemical structure of BindingDB Monomer ID 344027BDBM344027(US9777017, Example 11 | US9908895, Example 11 | US...)
Affinity DataIC50: 100nMAssay Description:Compounds herein were tested for inhibitory activity of JAK targets according to the following in vitro assay described in Park et al., Analytical Bi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2020
Entry Details
US Patent

TargetTyrosine-protein kinase JAK1 [837-1142](Human)
Incyte Holdings

US Patent
LigandChemical structure of BindingDB Monomer ID 344040BDBM344040(US9777017, Example 24 | US9908895, Example 24 | US...)
Affinity DataIC50: 100nMAssay Description:Compounds herein were tested for inhibitory activity of JAK targets according to the following in vitro assay described in Park et al., Analytical Bi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2020
Entry Details
US Patent

TargetTyrosine-protein kinase JAK1 [837-1142](Human)
Incyte Holdings

US Patent
LigandChemical structure of BindingDB Monomer ID 344098BDBM344098(US9777017, Example 82 | US9908895, Example 82 | US...)
Affinity DataIC50: 100nMAssay Description:Compounds herein were tested for inhibitory activity of JAK targets according to the following in vitro assay described in Park et al., Analytical Bi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2020
Entry Details
US Patent

TargetTyrosine-protein kinase JAK1 [837-1142](Human)
Incyte Holdings

US Patent
LigandChemical structure of BindingDB Monomer ID 344099BDBM344099(US9777017, Example 83 | US9908895, Example 83 | US...)
Affinity DataIC50: 100nMAssay Description:Compounds herein were tested for inhibitory activity of JAK targets according to the following in vitro assay described in Park et al., Analytical Bi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2020
Entry Details
US Patent

TargetTyrosine-protein kinase JAK1 [837-1142](Human)
Incyte Holdings

US Patent
LigandChemical structure of BindingDB Monomer ID 344096BDBM344096(US9777017, Example 80 | US9908895, Example 80 | US...)
Affinity DataIC50: 100nMAssay Description:Compounds herein were tested for inhibitory activity of JAK targets according to the following in vitro assay described in Park et al., Analytical Bi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2020
Entry Details
US Patent

TargetTyrosine-protein kinase JAK1 [837-1142](Human)
Incyte Holdings

US Patent
LigandChemical structure of BindingDB Monomer ID 344039BDBM344039(US9777017, Example 23 | US10370387, Example 23 | U...)
Affinity DataIC50: 100nMAssay Description:Compounds herein were tested for inhibitory activity of JAK targets according to the following in vitro assay described in Park et al., Analytical Bi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2020
Entry Details
US Patent

TargetTyrosine-protein kinase JAK1 [837-1142](Human)
Incyte Holdings

US Patent
LigandChemical structure of BindingDB Monomer ID 344097BDBM344097(US9777017, Example 81 | US9908895, Example 81 | US...)
Affinity DataIC50: 100nMAssay Description:Compounds herein were tested for inhibitory activity of JAK targets according to the following in vitro assay described in Park et al., Analytical Bi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2020
Entry Details
US Patent

TargetTyrosine-protein kinase JAK2 [828-1132](Human)
Incyte Holdings

US Patent
LigandChemical structure of BindingDB Monomer ID 344093BDBM344093(US9777017, Example 77 | US9908895, Example 77 | US...)
Affinity DataIC50: 100nMAssay Description:Compounds herein were tested for inhibitory activity of JAK targets according to the following in vitro assay described in Park et al., Analytical Bi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2020
Entry Details
US Patent

TargetTyrosine-protein kinase JAK1 [837-1142](Human)
Incyte Holdings

US Patent
LigandChemical structure of BindingDB Monomer ID 246852BDBM246852(((2R,5S)-5-{2-[(1R)- 1-hydroxyethyl]-1H- imidazo[4...)
Affinity DataIC50: 100nMAssay Description:Compounds herein were tested for inhibitory activity of JAK targets according to the following in vitro assay described in Park et al., Analytical Bi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2020
Entry Details
US Patent

TargetTyrosine-protein kinase JAK1 [837-1142](Human)
Incyte Holdings

US Patent
LigandChemical structure of BindingDB Monomer ID 410287BDBM410287(Methyl [(trans-4-{2-[(1R)-1-hydroxyethyl]-1H-imida...)
Affinity DataIC50: 100nMAssay Description:Compounds herein were tested for inhibitory activity of JAK targets according to the following in vitro assay described in Park et al., Analytical Bi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2020
Entry Details
US Patent

TargetTyrosine-protein kinase JAK1 [837-1142](Human)
Incyte Holdings

US Patent
LigandChemical structure of BindingDB Monomer ID 344095BDBM344095(US9777017, Example 79 | US9908895, Example 79 | US...)
Affinity DataIC50: 100nMAssay Description:Compounds herein were tested for inhibitory activity of JAK targets according to the following in vitro assay described in Park et al., Analytical Bi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2020
Entry Details
US Patent

TargetTyrosine-protein kinase JAK1 [837-1142](Human)
Incyte Holdings

US Patent
LigandChemical structure of BindingDB Monomer ID 344034BDBM344034(US9777017, Example 18 | US9908895, Example 18 | US...)
Affinity DataIC50: 100nMAssay Description:Compounds herein were tested for inhibitory activity of JAK targets according to the following in vitro assay described in Park et al., Analytical Bi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2020
Entry Details
US Patent

TargetTyrosine-protein kinase JAK1 [837-1142](Human)
Incyte Holdings

US Patent
LigandChemical structure of BindingDB Monomer ID 344092BDBM344092(US9777017, Example 76 | US9908895, Example 76 | US...)
Affinity DataIC50: 100nMAssay Description:Compounds herein were tested for inhibitory activity of JAK targets according to the following in vitro assay described in Park et al., Analytical Bi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2020
Entry Details
US Patent

TargetTyrosine-protein kinase JAK1 [837-1142](Human)
Incyte Holdings

US Patent
LigandChemical structure of BindingDB Monomer ID 344093BDBM344093(US9777017, Example 77 | US9908895, Example 77 | US...)
Affinity DataIC50: 100nMAssay Description:Compounds herein were tested for inhibitory activity of JAK targets according to the following in vitro assay described in Park et al., Analytical Bi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2020
Entry Details
US Patent

TargetTyrosine-protein kinase JAK1 [837-1142](Human)
Incyte Holdings

US Patent
LigandChemical structure of BindingDB Monomer ID 344106BDBM344106(US9777017, Example 90 | US9908895, Example 90 | US...)
Affinity DataIC50: 100nMAssay Description:Compounds herein were tested for inhibitory activity of JAK targets according to the following in vitro assay described in Park et al., Analytical Bi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2020
Entry Details
US Patent

TargetTyrosine-protein kinase JAK1 [837-1142](Human)
Incyte Holdings

US Patent
LigandChemical structure of BindingDB Monomer ID 344107BDBM344107(US9777017, Example 91 | US9908895, Example 91 | US...)
Affinity DataIC50: 100nMAssay Description:Compounds herein were tested for inhibitory activity of JAK targets according to the following in vitro assay described in Park et al., Analytical Bi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2020
Entry Details
US Patent

TargetTyrosine-protein kinase JAK1 [837-1142](Human)
Incyte Holdings

US Patent
LigandChemical structure of BindingDB Monomer ID 344104BDBM344104(US9777017, Example 88 | US9908895, Example 88 | US...)
Affinity DataIC50: 100nMAssay Description:Compounds herein were tested for inhibitory activity of JAK targets according to the following in vitro assay described in Park et al., Analytical Bi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2020
Entry Details
US Patent

TargetTyrosine-protein kinase JAK1 [837-1142](Human)
Incyte Holdings

US Patent
LigandChemical structure of BindingDB Monomer ID 344105BDBM344105(US9777017, Example 89 | US9908895, Example 89 | US...)
Affinity DataIC50: 100nMAssay Description:Compounds herein were tested for inhibitory activity of JAK targets according to the following in vitro assay described in Park et al., Analytical Bi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2020
Entry Details
US Patent

TargetTyrosine-protein kinase JAK1 [837-1142](Human)
Incyte Holdings

US Patent
LigandChemical structure of BindingDB Monomer ID 344043BDBM344043(US9777017, Example 27 | US9908895, Example 27 | US...)
Affinity DataIC50: 100nMAssay Description:Compounds herein were tested for inhibitory activity of JAK targets according to the following in vitro assay described in Park et al., Analytical Bi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2020
Entry Details
US Patent

TargetTyrosine-protein kinase JAK1 [837-1142](Human)
Incyte Holdings

US Patent
LigandChemical structure of BindingDB Monomer ID 344102BDBM344102(US9777017, Example 86 | US9908895, Example 86 | US...)
Affinity DataIC50: 100nMAssay Description:Compounds herein were tested for inhibitory activity of JAK targets according to the following in vitro assay described in Park et al., Analytical Bi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2020
Entry Details
US Patent

TargetTyrosine-protein kinase JAK1 [837-1142](Human)
Incyte Holdings

US Patent
LigandChemical structure of BindingDB Monomer ID 344103BDBM344103(US9777017, Example 87 | US9908895, Example 87 | US...)
Affinity DataIC50: 100nMAssay Description:Compounds herein were tested for inhibitory activity of JAK targets according to the following in vitro assay described in Park et al., Analytical Bi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2020
Entry Details
US Patent

TargetTyrosine-protein kinase JAK1 [837-1142](Human)
Incyte Holdings

US Patent
LigandChemical structure of BindingDB Monomer ID 344041BDBM344041(US9777017, Example 25 | US9908895, Example 25 | US...)
Affinity DataIC50: 100nMAssay Description:Compounds herein were tested for inhibitory activity of JAK targets according to the following in vitro assay described in Park et al., Analytical Bi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2020
Entry Details
US Patent

TargetTyrosine-protein kinase JAK1 [837-1142](Human)
Incyte Holdings

US Patent
LigandChemical structure of BindingDB Monomer ID 344100BDBM344100(US9777017, Example 84 | US9908895, Example 84 | US...)
Affinity DataIC50: 100nMAssay Description:Compounds herein were tested for inhibitory activity of JAK targets according to the following in vitro assay described in Park et al., Analytical Bi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2020
Entry Details
US Patent

TargetTyrosine-protein kinase JAK1 [837-1142](Human)
Incyte Holdings

US Patent
LigandChemical structure of BindingDB Monomer ID 344042BDBM344042(US9777017, Example 26 | US9908895, Example 26 | US...)
Affinity DataIC50: 100nMAssay Description:Compounds herein were tested for inhibitory activity of JAK targets according to the following in vitro assay described in Park et al., Analytical Bi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2020
Entry Details
US Patent

TargetTyrosine-protein kinase JAK1 [837-1142](Human)
Incyte Holdings

US Patent
LigandChemical structure of BindingDB Monomer ID 344101BDBM344101(US9777017, Example 85 | US9908895, Example 85 | US...)
Affinity DataIC50: 100nMAssay Description:Compounds herein were tested for inhibitory activity of JAK targets according to the following in vitro assay described in Park et al., Analytical Bi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2020
Entry Details
US Patent

TargetTyrosine-protein kinase JAK1 [837-1142](Human)
Incyte Holdings

US Patent
LigandChemical structure of BindingDB Monomer ID 410242BDBM410242(US10370387, Example 37-2 | US10370387, Example 36-...)
Affinity DataIC50: 100nMAssay Description:Compounds herein were tested for inhibitory activity of JAK targets according to the following in vitro assay described in Park et al., Analytical Bi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2020
Entry Details
US Patent

TargetTyrosine-protein kinase JAK1 [837-1142](Human)
Incyte Holdings

US Patent
LigandChemical structure of BindingDB Monomer ID 410241BDBM410241(((1R,2R,4S)-2-Hydroxy-4-{2-[(1R)-1-hydroxyethyl]-1...)
Affinity DataIC50: 100nMAssay Description:Compounds herein were tested for inhibitory activity of JAK targets according to the following in vitro assay described in Park et al., Analytical Bi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2020
Entry Details
US Patent

TargetTyrosine-protein kinase JAK1 [837-1142](Human)
Incyte Holdings

US Patent
LigandChemical structure of BindingDB Monomer ID 410242BDBM410242(US10370387, Example 37-2 | US10370387, Example 36-...)
Affinity DataIC50: 100nMAssay Description:Compounds herein were tested for inhibitory activity of JAK targets according to the following in vitro assay described in Park et al., Analytical Bi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2020
Entry Details
US Patent

TargetTyrosine-protein kinase JAK1 [837-1142](Human)
Incyte Holdings

US Patent
LigandChemical structure of BindingDB Monomer ID 344051BDBM344051(US9777017, Example 35 | US9908895, Example 35 | US...)
Affinity DataIC50: 100nMAssay Description:Compounds herein were tested for inhibitory activity of JAK targets according to the following in vitro assay described in Park et al., Analytical Bi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2020
Entry Details
US Patent

TargetTyrosine-protein kinase JAK1 [837-1142](Human)
Incyte Holdings

US Patent
LigandChemical structure of BindingDB Monomer ID 344048BDBM344048(US9777017, Example 32 | US9908895, Example 32 | US...)
Affinity DataIC50: 100nMAssay Description:Compounds herein were tested for inhibitory activity of JAK targets according to the following in vitro assay described in Park et al., Analytical Bi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2020
Entry Details
US Patent

TargetTyrosine-protein kinase JAK1 [837-1142](Human)
Incyte Holdings

US Patent
LigandChemical structure of BindingDB Monomer ID 344049BDBM344049(US9777017, Example 33 | US9908895, Example 33 | US...)
Affinity DataIC50: 100nMAssay Description:Compounds herein were tested for inhibitory activity of JAK targets according to the following in vitro assay described in Park et al., Analytical Bi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2020
Entry Details
US Patent

TargetTyrosine-protein kinase JAK1 [837-1142](Human)
Incyte Holdings

US Patent
LigandChemical structure of BindingDB Monomer ID 344058BDBM344058(US9777017, Example 42 | US9908895, Example 42 | US...)
Affinity DataIC50: 100nMAssay Description:Compounds herein were tested for inhibitory activity of JAK targets according to the following in vitro assay described in Park et al., Analytical Bi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2020
Entry Details
US Patent

TargetTyrosine-protein kinase JAK1 [837-1142](Human)
Incyte Holdings

US Patent
LigandChemical structure of BindingDB Monomer ID 344059BDBM344059(US9777017, Example 43 | US9908895, Example 43 | US...)
Affinity DataIC50: 100nMAssay Description:Compounds herein were tested for inhibitory activity of JAK targets according to the following in vitro assay described in Park et al., Analytical Bi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2020
Entry Details
US Patent

TargetTyrosine-protein kinase JAK1 [837-1142](Human)
Incyte Holdings

US Patent
LigandChemical structure of BindingDB Monomer ID 410249BDBM410249([(1R,2S,4S)-4-(2-Methyl-1H-imidazo[4,5-d]thieno[3,...)
Affinity DataIC50: 100nMAssay Description:Compounds herein were tested for inhibitory activity of JAK targets according to the following in vitro assay described in Park et al., Analytical Bi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2020
Entry Details
US Patent

TargetTyrosine-protein kinase JAK1 [837-1142](Human)
Incyte Holdings

US Patent
LigandChemical structure of BindingDB Monomer ID 375666BDBM375666(US9908895, Example 40 | US9908895, Example 41 | US...)
Affinity DataIC50: 100nMAssay Description:Compounds herein were tested for inhibitory activity of JAK targets according to the following in vitro assay described in Park et al., Analytical Bi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2020
Entry Details
US Patent

TargetTyrosine-protein kinase JAK1 [837-1142](Human)
Incyte Holdings

US Patent
LigandChemical structure of BindingDB Monomer ID 344054BDBM344054(US9777017, Example 38 | US9908895, Example 38 | US...)
Affinity DataIC50: 100nMAssay Description:Compounds herein were tested for inhibitory activity of JAK targets according to the following in vitro assay described in Park et al., Analytical Bi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2020
Entry Details
US Patent

TargetTyrosine-protein kinase JAK2 [828-1132](Human)
Incyte Holdings

US Patent
LigandChemical structure of BindingDB Monomer ID 344054BDBM344054(US9777017, Example 38 | US9908895, Example 38 | US...)
Affinity DataIC50: 100nMAssay Description:Compounds herein were tested for inhibitory activity of JAK targets according to the following in vitro assay described in Park et al., Analytical Bi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2020
Entry Details
US Patent

TargetTyrosine-protein kinase JAK1 [837-1142](Human)
Incyte Holdings

US Patent
LigandChemical structure of BindingDB Monomer ID 344055BDBM344055(US9777017, Example 39 | US9908895, Example 39 | US...)
Affinity DataIC50: 100nMAssay Description:Compounds herein were tested for inhibitory activity of JAK targets according to the following in vitro assay described in Park et al., Analytical Bi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2020
Entry Details
US Patent

TargetTyrosine-protein kinase JAK1 [837-1142](Human)
Incyte Holdings

US Patent
LigandChemical structure of BindingDB Monomer ID 344064BDBM344064(US9777017, Example 48 | US9908895, Example 48 | US...)
Affinity DataIC50: 100nMAssay Description:Compounds herein were tested for inhibitory activity of JAK targets according to the following in vitro assay described in Park et al., Analytical Bi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2020
Entry Details
US Patent

TargetTyrosine-protein kinase JAK2 [828-1132](Human)
Incyte Holdings

US Patent
LigandChemical structure of BindingDB Monomer ID 344064BDBM344064(US9777017, Example 48 | US9908895, Example 48 | US...)
Affinity DataIC50: 100nMAssay Description:Compounds herein were tested for inhibitory activity of JAK targets according to the following in vitro assay described in Park et al., Analytical Bi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2020
Entry Details
US Patent

TargetTyrosine-protein kinase JAK1 [837-1142](Human)
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US Patent
LigandChemical structure of BindingDB Monomer ID 410255BDBM410255([4-(8-Methylpyrazolo[1,5-c]thieno[2,3-e]pyrimidin-...)
Affinity DataIC50: 100nMAssay Description:Compounds herein were tested for inhibitory activity of JAK targets according to the following in vitro assay described in Park et al., Analytical Bi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2020
Entry Details
US Patent

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