Compile Data Set for Download or QSAR
Report error Found 634 Enz. Inhib. hit(s) with all data for entry = 8633
TargetGlutamate receptor ionotropic, NMDA 2B(Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 409275BDBM409275(2-[6-(4-Fluoro-3-methyl-phenyl)pyrrolo[3,2-b]pyrid...)
Affinity DataIC50: 2nMAssay Description:The assay depends on the binding of a tracer to the GluN2B subunit-containing NMDA receptors and the ability of the test compounds to displace such b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2020
Entry Details
US Patent

TargetGlutamate receptor ionotropic, NMDA 2B(Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 409513BDBM409513(2-[6-(5-Chloro-2-thienyl)pyrrolo[3,2-b]pyridin-1-y...)
Affinity DataIC50: 6.31nMAssay Description:The assay depends on the binding of a tracer to the GluN2B subunit-containing NMDA receptors and the ability of the test compounds to displace such b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2020
Entry Details
US Patent

TargetGlutamate receptor ionotropic, NMDA 2B(Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 409743BDBM409743(2-[6-(3,5-Difluorophenyl)-3-(trifluoromethyl)pyrro...)
Affinity DataIC50: 10nMAssay Description:The assay depends on the binding of a tracer to the GluN2B subunit-containing NMDA receptors and the ability of the test compounds to displace such b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2020
Entry Details
US Patent

TargetGlutamate receptor ionotropic, NMDA 2B(Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 409515BDBM409515(1-(Azetidin-1-yl)-2-[6-(5-methyl-2-thienyl)pyrrolo...)
Affinity DataIC50: 10nMAssay Description:The assay depends on the binding of a tracer to the GluN2B subunit-containing NMDA receptors and the ability of the test compounds to displace such b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2020
Entry Details
US Patent

TargetGlutamate receptor ionotropic, NMDA 2B(Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 409623BDBM409623(2-[6-(3-Chlorophenyl)-3-fluoro-pyrrolo[3,2-b]pyrid...)
Affinity DataIC50: 10nMAssay Description:The assay depends on the binding of a tracer to the GluN2B subunit-containing NMDA receptors and the ability of the test compounds to displace such b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2020
Entry Details
US Patent

TargetGlutamate receptor ionotropic, NMDA 2B(Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 409512BDBM409512(2-[6-[3-(Difluoromethyl)phenyl]pyrrolo[3,2-b]pyrid...)
Affinity DataIC50: 10nMAssay Description:The assay depends on the binding of a tracer to the GluN2B subunit-containing NMDA receptors and the ability of the test compounds to displace such b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2020
Entry Details
US Patent

TargetGlutamate receptor ionotropic, NMDA 2B(Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 409735BDBM409735(2-[3-Chloro-6-(5-chloro-4-methyl-2-thienyl)pyrrolo...)
Affinity DataIC50: 10nMAssay Description:The assay depends on the binding of a tracer to the GluN2B subunit-containing NMDA receptors and the ability of the test compounds to displace such b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2020
Entry Details
US Patent

TargetGlutamate receptor ionotropic, NMDA 2B(Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 409475BDBM409475(4-[6-(4-Fluorophenyl)pyrrolo[3,2-b]pyridin-1-yl]bu...)
Affinity DataIC50: 12.6nMAssay Description:The assay depends on the binding of a tracer to the GluN2B subunit-containing NMDA receptors and the ability of the test compounds to displace such b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2020
Entry Details
US Patent

TargetGlutamate receptor ionotropic, NMDA 2B(Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 409510BDBM409510(N,N-Dimethyl-2-[6-(3,4,5-trifluorophenyl)pyrrolo[3...)
Affinity DataIC50: 12.6nMAssay Description:The assay depends on the binding of a tracer to the GluN2B subunit-containing NMDA receptors and the ability of the test compounds to displace such b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2020
Entry Details
US Patent

TargetGlutamate receptor ionotropic, NMDA 2B(Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 409638BDBM409638(2-[6-(3-Chloro-4-fluoro-phenyl)-3-fluoro-pyrrolo[3...)
Affinity DataIC50: 12.6nMAssay Description:The assay depends on the binding of a tracer to the GluN2B subunit-containing NMDA receptors and the ability of the test compounds to displace such b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2020
Entry Details
US Patent

TargetGlutamate receptor ionotropic, NMDA 2B(Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 409678BDBM409678(2-[3-Chloro-6-(3-chlorophenyl)pyrrolo[3,2-b]pyridi...)
Affinity DataIC50: 12.6nMAssay Description:The assay depends on the binding of a tracer to the GluN2B subunit-containing NMDA receptors and the ability of the test compounds to displace such b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2020
Entry Details
US Patent

TargetGlutamate receptor ionotropic, NMDA 2B(Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 409474BDBM409474(1-[3-Fluoro-6-(4-methyl-2-thienyl)pyrrolo[3,2-b]py...)
Affinity DataIC50: 12.6nMAssay Description:The assay depends on the binding of a tracer to the GluN2B subunit-containing NMDA receptors and the ability of the test compounds to displace such b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2020
Entry Details
US Patent

TargetGlutamate receptor ionotropic, NMDA 2B(Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 409618BDBM409618(1-(3-Fluoroazetidin-1-yl)-2-[3-fluoro-6-[3- | US10...)
Affinity DataIC50: 12.6nMAssay Description:The assay depends on the binding of a tracer to the GluN2B subunit-containing NMDA receptors and the ability of the test compounds to displace such b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2020
Entry Details
US Patent

TargetGlutamate receptor ionotropic, NMDA 2B(Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 409629BDBM409629(2-(3-Fluoro-6-phenyl-pyrrolo[3,2-b]pyridin-1-yl)-N...)
Affinity DataIC50: 12.6nMAssay Description:The assay depends on the binding of a tracer to the GluN2B subunit-containing NMDA receptors and the ability of the test compounds to displace such b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2020
Entry Details
US Patent

TargetGlutamate receptor ionotropic, NMDA 2B(Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 409470BDBM409470(1-[3-Fluoro-6-(4-fluoro-3-methyl-phenyl)pyrrolo[3,...)
Affinity DataIC50: 12.6nMAssay Description:The assay depends on the binding of a tracer to the GluN2B subunit-containing NMDA receptors and the ability of the test compounds to displace such b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2020
Entry Details
US Patent

TargetGlutamate receptor ionotropic, NMDA 2B(Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 409598BDBM409598(N-Ethyl-2-[6-[2-fluoro-3-(trifluoromethyl)phenyl]p...)
Affinity DataIC50: 12.6nMAssay Description:The assay depends on the binding of a tracer to the GluN2B subunit-containing NMDA receptors and the ability of the test compounds to displace such b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2020
Entry Details
US Patent

TargetGlutamate receptor ionotropic, NMDA 2B(Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 409670BDBM409670(2-[3-Chloro-6-(3,5-difluorophenyl)pyrrolo[3,2-b]py...)
Affinity DataIC50: 12.6nMAssay Description:The assay depends on the binding of a tracer to the GluN2B subunit-containing NMDA receptors and the ability of the test compounds to displace such b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2020
Entry Details
US Patent

TargetGlutamate receptor ionotropic, NMDA 2B(Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 409091BDBM409091(2-[3-Chloro-6-(3,4-difluorophenyl)pyrrolo[3,2-b]py...)
Affinity DataIC50: 15.8nMAssay Description:The assay depends on the binding of a tracer to the GluN2B subunit-containing NMDA receptors and the ability of the test compounds to displace such b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2020
Entry Details
US Patent

TargetGlutamate receptor ionotropic, NMDA 2B(Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 409622BDBM409622(2-[6-(2,4-Difluoro-3-methyl-phenyl)-3-fluoro-pyrro...)
Affinity DataIC50: 15.8nMAssay Description:The assay depends on the binding of a tracer to the GluN2B subunit-containing NMDA receptors and the ability of the test compounds to displace such b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2020
Entry Details
US Patent

TargetGlutamate receptor ionotropic, NMDA 2B(Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 409616BDBM409616(1-(3-Fluoroazetidin-1-yl)-2-(3-fluoro-6-phenyl-pyr...)
Affinity DataIC50: 15.8nMAssay Description:The assay depends on the binding of a tracer to the GluN2B subunit-containing NMDA receptors and the ability of the test compounds to displace such b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2020
Entry Details
US Patent

TargetGlutamate receptor ionotropic, NMDA 2B(Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 409516BDBM409516(1-(Azetidin-1-yl)-2-[3-chloro-6-(5-chloro-2-thieny...)
Affinity DataIC50: 15.8nMAssay Description:The assay depends on the binding of a tracer to the GluN2B subunit-containing NMDA receptors and the ability of the test compounds to displace such b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2020
Entry Details
US Patent

TargetGlutamate receptor ionotropic, NMDA 2B(Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 409485BDBM409485(N-Cyclopropyl-2-[6-(3,5-difluorophenyl)pyrrolo[3,2...)
Affinity DataIC50: 15.8nMAssay Description:The assay depends on the binding of a tracer to the GluN2B subunit-containing NMDA receptors and the ability of the test compounds to displace such b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2020
Entry Details
US Patent

TargetGlutamate receptor ionotropic, NMDA 2B(Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 409517BDBM409517(1-(Azetidin-1-yl)-2-[6-(3,4-difluorophenyl)-3-fluo...)
Affinity DataIC50: 15.8nMAssay Description:The assay depends on the binding of a tracer to the GluN2B subunit-containing NMDA receptors and the ability of the test compounds to displace such b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2020
Entry Details
US Patent

TargetGlutamate receptor ionotropic, NMDA 2B(Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 409518BDBM409518(1-(Azetidin-1-yl)-2-[3-fluoro-6-(3,4,5-trifluoroph...)
Affinity DataIC50: 15.8nMAssay Description:The assay depends on the binding of a tracer to the GluN2B subunit-containing NMDA receptors and the ability of the test compounds to displace such b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2020
Entry Details
US Patent

TargetGlutamate receptor ionotropic, NMDA 2B(Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 409640BDBM409640(1-(Azetidin-1-yl)-2-[3-fluoro-6-(3-fluorophenyl)py...)
Affinity DataIC50: 15.8nMAssay Description:The assay depends on the binding of a tracer to the GluN2B subunit-containing NMDA receptors and the ability of the test compounds to displace such b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2020
Entry Details
US Patent

TargetGlutamate receptor ionotropic, NMDA 2B(Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 409507BDBM409507(2-[6-(5-Chloro-2-thienyl)pyrrolo[3,2-b]pyridin-1-y...)
Affinity DataIC50: 15.8nMAssay Description:The assay depends on the binding of a tracer to the GluN2B subunit-containing NMDA receptors and the ability of the test compounds to displace such b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2020
Entry Details
US Patent

TargetGlutamate receptor ionotropic, NMDA 2B(Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 409603BDBM409603(2-[6-(2,4-Difluoro-3-methyl-phenyl)pyrrolo[3,2-b]p...)
Affinity DataIC50: 15.8nMAssay Description:The assay depends on the binding of a tracer to the GluN2B subunit-containing NMDA receptors and the ability of the test compounds to displace such b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2020
Entry Details
US Patent

TargetGlutamate receptor ionotropic, NMDA 2B(Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 409637BDBM409637(2-[6-(3-Chlorophenyl)-3-fluoro-pyrrolo[3,2-b]pyrid...)
Affinity DataIC50: 15.8nMAssay Description:The assay depends on the binding of a tracer to the GluN2B subunit-containing NMDA receptors and the ability of the test compounds to displace such b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2020
Entry Details
US Patent

TargetGlutamate receptor ionotropic, NMDA 2B(Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 409472BDBM409472(1-[6-[3-(Difluoromethyl)phenyl]-3-fluoro-pyrrolo[3...)
Affinity DataIC50: 15.8nMAssay Description:The assay depends on the binding of a tracer to the GluN2B subunit-containing NMDA receptors and the ability of the test compounds to displace such b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2020
Entry Details
US Patent

TargetGlutamate receptor ionotropic, NMDA 2B(Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 409473BDBM409473(1-[6-(5-Chloro-2-thienyl)-3-fluoro-pyrrolo[3,2-b]p...)
Affinity DataIC50: 15.8nMAssay Description:The assay depends on the binding of a tracer to the GluN2B subunit-containing NMDA receptors and the ability of the test compounds to displace such b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2020
Entry Details
US Patent

TargetGlutamate receptor ionotropic, NMDA 2B(Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 409506BDBM409506(1-(3-Fluoroazetidin-1-yl)-2-[6-(3,4,5-trifluorophe...)
Affinity DataIC50: 15.8nMAssay Description:The assay depends on the binding of a tracer to the GluN2B subunit-containing NMDA receptors and the ability of the test compounds to displace such b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2020
Entry Details
US Patent

TargetGlutamate receptor ionotropic, NMDA 2B(Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 409602BDBM409602(2-[6-(3-Chloro-4-fluoro-phenyl)pyrrolo[3,2-b]pyrid...)
Affinity DataIC50: 15.8nMAssay Description:The assay depends on the binding of a tracer to the GluN2B subunit-containing NMDA receptors and the ability of the test compounds to displace such b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2020
Entry Details
US Patent

TargetGlutamate receptor ionotropic, NMDA 2B(Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 409755BDBM409755(2-[6-(3,5-Difluorophenyl)-3-methyl-pyrrolo[3,2-b]p...)
Affinity DataIC50: 15.8nMAssay Description:The assay depends on the binding of a tracer to the GluN2B subunit-containing NMDA receptors and the ability of the test compounds to displace such b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2020
Entry Details
US Patent

TargetGlutamate receptor ionotropic, NMDA 2B(Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 409591BDBM409591(1-(3-Fluoroazetidin-1-yl)-2-[6-(2-fluorophenyl)pyr...)
Affinity DataIC50: 15.8nMAssay Description:The assay depends on the binding of a tracer to the GluN2B subunit-containing NMDA receptors and the ability of the test compounds to displace such b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2020
Entry Details
US Patent

TargetGlutamate receptor ionotropic, NMDA 2B(Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 409625BDBM409625(2-[6-(3-Ethylphenyl)-3-fluoro-pyrrolo[3,2-b]pyridi...)
Affinity DataIC50: 15.8nMAssay Description:The assay depends on the binding of a tracer to the GluN2B subunit-containing NMDA receptors and the ability of the test compounds to displace such b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2020
Entry Details
US Patent

TargetGlutamate receptor ionotropic, NMDA 2B(Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 409491BDBM409491(1-(Azetidin-1-yl)-2-[6-(m-tolyl)pyrrolo[3,2-b]pyri...)
Affinity DataIC50: 20nMAssay Description:The assay depends on the binding of a tracer to the GluN2B subunit-containing NMDA receptors and the ability of the test compounds to displace such b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2020
Entry Details
US Patent

TargetGlutamate receptor ionotropic, NMDA 2B(Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 409492BDBM409492(1-(Azetidin-1-yl)-2-[6-(3,4-dichlorophenyl)pyrrolo...)
Affinity DataIC50: 20nMAssay Description:The assay depends on the binding of a tracer to the GluN2B subunit-containing NMDA receptors and the ability of the test compounds to displace such b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2020
Entry Details
US Patent

TargetGlutamate receptor ionotropic, NMDA 2B(Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 409086BDBM409086(1-(Azetidin-1-yl)-2-[3-chloro-6-(3,4-difluoropheny...)
Affinity DataIC50: 20nMAssay Description:The assay depends on the binding of a tracer to the GluN2B subunit-containing NMDA receptors and the ability of the test compounds to displace such b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2020
Entry Details
US Patent

TargetGlutamate receptor ionotropic, NMDA 2B(Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 409417BDBM409417(2-[6-(4-Chloro-2-thienyl)pyrrolo[3,2-b]pyridin-1-y...)
Affinity DataIC50: 20nMAssay Description:The assay depends on the binding of a tracer to the GluN2B subunit-containing NMDA receptors and the ability of the test compounds to displace such b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2020
Entry Details
US Patent

TargetGlutamate receptor ionotropic, NMDA 2B(Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 409087BDBM409087(2-[3-Chloro-6-(3,4-difluorophenyl)pyrrolo[3,2-b]py...)
Affinity DataIC50: 20nMAssay Description:The assay depends on the binding of a tracer to the GluN2B subunit-containing NMDA receptors and the ability of the test compounds to displace such b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2020
Entry Details
US Patent

TargetGlutamate receptor ionotropic, NMDA 2B(Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 409676BDBM409676(2-[3-Chloro-6-(3-fluorophenyl)pyrrolo[3,2-b]pyridi...)
Affinity DataIC50: 20nMAssay Description:The assay depends on the binding of a tracer to the GluN2B subunit-containing NMDA receptors and the ability of the test compounds to displace such b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2020
Entry Details
US Patent

TargetGlutamate receptor ionotropic, NMDA 2B(Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 409741BDBM409741(2-[6-(3-Chloro-4-fluoro-phenyl)-3-fluoro-pyrrolo[3...)
Affinity DataIC50: 20nMAssay Description:The assay depends on the binding of a tracer to the GluN2B subunit-containing NMDA receptors and the ability of the test compounds to displace such b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2020
Entry Details
US Patent

TargetGlutamate receptor ionotropic, NMDA 2B(Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 409409BDBM409409(2-[6-(5-Ethyl-2-thienyl)pyrrolo[3,2-b]pyridin-1-yl...)
Affinity DataIC50: 20nMAssay Description:The assay depends on the binding of a tracer to the GluN2B subunit-containing NMDA receptors and the ability of the test compounds to displace such b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2020
Entry Details
US Patent

TargetGlutamate receptor ionotropic, NMDA 2B(Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 409508BDBM409508(1-(Azetidin-1-yl)-2-[6-(5-chloro-2-thienyl)pyrrolo...)
Affinity DataIC50: 20nMAssay Description:The assay depends on the binding of a tracer to the GluN2B subunit-containing NMDA receptors and the ability of the test compounds to displace such b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2020
Entry Details
US Patent

TargetGlutamate receptor ionotropic, NMDA 2B(Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 409509BDBM409509(2-[3-Chloro-6-(2,3,4-trifluorophenyl)pyrrolo[3,2-b...)
Affinity DataIC50: 20nMAssay Description:The assay depends on the binding of a tracer to the GluN2B subunit-containing NMDA receptors and the ability of the test compounds to displace such b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2020
Entry Details
US Patent

TargetGlutamate receptor ionotropic, NMDA 2B(Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 409504BDBM409504(2-[6-(4-Methyl-2-thienyl)pyrrolo[3,2-b]pyridin-1-y...)
Affinity DataIC50: 20nMAssay Description:The assay depends on the binding of a tracer to the GluN2B subunit-containing NMDA receptors and the ability of the test compounds to displace such b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2020
Entry Details
US Patent

TargetGlutamate receptor ionotropic, NMDA 2B(Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 409431BDBM409431(2-(3-Chloro-6-phenyl-pyrrolo[3,2-b]pyridin-1-yl)-1...)
Affinity DataIC50: 20nMAssay Description:The assay depends on the binding of a tracer to the GluN2B subunit-containing NMDA receptors and the ability of the test compounds to displace such b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2020
Entry Details
US Patent

TargetGlutamate receptor ionotropic, NMDA 2B(Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 409499BDBM409499(1-[6-(3,5-Difluorophenyl)pyrrolo[3,2-b]pyridin-1-y...)
Affinity DataIC50: 20nMAssay Description:The assay depends on the binding of a tracer to the GluN2B subunit-containing NMDA receptors and the ability of the test compounds to displace such b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2020
Entry Details
US Patent

TargetGlutamate receptor ionotropic, NMDA 2B(Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 409432BDBM409432(1-(Azetidin-1-yl)-2-[3-chloro-6-(3,4,5-trifluoroph...)
Affinity DataIC50: 20nMAssay Description:The assay depends on the binding of a tracer to the GluN2B subunit-containing NMDA receptors and the ability of the test compounds to displace such b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2020
Entry Details
US Patent

TargetGlutamate receptor ionotropic, NMDA 2B(Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 409500BDBM409500(1-Cyclobutyl-2-[6-(4-fluorophenyl)pyrrolo[3,2-b]py...)
Affinity DataIC50: 20nMAssay Description:The assay depends on the binding of a tracer to the GluN2B subunit-containing NMDA receptors and the ability of the test compounds to displace such b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2020
Entry Details
US Patent

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