Compile Data Set for Download or QSAR
Report error Found 47 Enz. Inhib. hit(s) with all data for entry = 8719
TargetInterleukin-1 receptor-associated kinase 4(Human)
Bayer Pharma Aktiegesellschaft

US Patent
LigandChemical structure of BindingDB Monomer ID 414479BDBM414479(Methyl 2-(1-methylpiperidin-4-yl)-5-({[6-(trifluor...)
Affinity DataIC50: 1nMAssay Description:For the assay, 11 different concentrations in the range from 20 μM to 0.073 nM were prepared from a 2 mM solution of the test substance in DMSO....More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details
US Patent

TargetInterleukin-1 receptor-associated kinase 4(Human)
Bayer Pharma Aktiegesellschaft

US Patent
LigandChemical structure of BindingDB Monomer ID 414436BDBM414436(N-{2-[1-(2-Hydroxyethyl)piperidin-4-yl]-6-methoxy-...)
Affinity DataIC50: 1nMAssay Description:For the assay, 11 different concentrations in the range from 20 μM to 0.073 nM were prepared from a 2 mM solution of the test substance in DMSO....More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details
US Patent

TargetInterleukin-1 receptor-associated kinase 4(Human)
Bayer Pharma Aktiegesellschaft

US Patent
LigandChemical structure of BindingDB Monomer ID 414432BDBM414432(N-(2-{1-[2-(Dimethylamino)ethyl]piperidin-4-yl}-6-...)
Affinity DataIC50: 1nMAssay Description:For the assay, 11 different concentrations in the range from 20 μM to 0.073 nM were prepared from a 2 mM solution of the test substance in DMSO....More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details
US Patent

TargetInterleukin-1 receptor-associated kinase 4(Human)
Bayer Pharma Aktiegesellschaft

US Patent
LigandChemical structure of BindingDB Monomer ID 414476BDBM414476(N-{2-[1-(3-Hydroxy-3-methylbutyl)piperidin-4-yl]-6...)
Affinity DataIC50: 1nMAssay Description:For the assay, 11 different concentrations in the range from 20 μM to 0.073 nM were prepared from a 2 mM solution of the test substance in DMSO....More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details
US Patent

TargetInterleukin-1 receptor-associated kinase 4(Human)
Bayer Pharma Aktiegesellschaft

US Patent
LigandChemical structure of BindingDB Monomer ID 414477BDBM414477(2-(Piperidin-4-yl)-5-({[6-(trifluoromethyl)pyridin...)
Affinity DataIC50: 1nMAssay Description:For the assay, 11 different concentrations in the range from 20 μM to 0.073 nM were prepared from a 2 mM solution of the test substance in DMSO....More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details
US Patent

TargetInterleukin-1 receptor-associated kinase 4(Human)
Bayer Pharma Aktiegesellschaft

US Patent
LigandChemical structure of BindingDB Monomer ID 414444BDBM414444(6-(Difluoromethyl)-N-[6-methoxy-2-(tetrahydro-2H-p...)
Affinity DataIC50: 1nMAssay Description:For the assay, 11 different concentrations in the range from 20 μM to 0.073 nM were prepared from a 2 mM solution of the test substance in DMSO....More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details
US Patent

TargetInterleukin-1 receptor-associated kinase 4(Human)
Bayer Pharma Aktiegesellschaft

US Patent
LigandChemical structure of BindingDB Monomer ID 414423BDBM414423(N-[6-Methoxy-2-(1-methylpiperidin-4-yl)-2H-indazol...)
Affinity DataIC50: 1nMAssay Description:For the assay, 11 different concentrations in the range from 20 μM to 0.073 nM were prepared from a 2 mM solution of the test substance in DMSO....More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details
US Patent

TargetInterleukin-1 receptor-associated kinase 4(Human)
Bayer Pharma Aktiegesellschaft

US Patent
LigandChemical structure of BindingDB Monomer ID 414421BDBM414421(N-[6-Methoxy-2-(piperidin-4-yl)-2H-indazol-5-yl]-6...)
Affinity DataIC50: 1nMAssay Description:For the assay, 11 different concentrations in the range from 20 μM to 0.073 nM were prepared from a 2 mM solution of the test substance in DMSO....More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details
US Patent

TargetInterleukin-1 receptor-associated kinase 4(Human)
Bayer Pharma Aktiegesellschaft

US Patent
LigandChemical structure of BindingDB Monomer ID 414435BDBM414435(rac-N-[6-Methoxy-2-(1-oxidotetrahydro-2H-thiopyran...)
Affinity DataIC50: 2nMAssay Description:For the assay, 11 different concentrations in the range from 20 μM to 0.073 nM were prepared from a 2 mM solution of the test substance in DMSO....More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details
US Patent

TargetInterleukin-1 receptor-associated kinase 4(Human)
Bayer Pharma Aktiegesellschaft

US Patent
LigandChemical structure of BindingDB Monomer ID 414481BDBM414481(2-(1-Methylpiperidin-4-yl)-5-({[6-(trifluoromethyl...)
Affinity DataIC50: 2nMAssay Description:For the assay, 11 different concentrations in the range from 20 μM to 0.073 nM were prepared from a 2 mM solution of the test substance in DMSO....More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details
US Patent

TargetInterleukin-1 receptor-associated kinase 4(Human)
Bayer Pharma Aktiegesellschaft

US Patent
LigandChemical structure of BindingDB Monomer ID 414439BDBM414439(rel-N-{6-Methoxy-2-[(1S,4S,5R)-2-methyl-2-azabicyc...)
Affinity DataIC50: 2nMAssay Description:For the assay, 11 different concentrations in the range from 20 μM to 0.073 nM were prepared from a 2 mM solution of the test substance in DMSO....More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details
US Patent

TargetInterleukin-1 receptor-associated kinase 4(Human)
Bayer Pharma Aktiegesellschaft

US Patent
LigandChemical structure of BindingDB Monomer ID 414445BDBM414445(N-[6-Methoxy-2-(tetrahydro-2H-pyran-4-yl)-2H-indaz...)
Affinity DataIC50: 2nMAssay Description:For the assay, 11 different concentrations in the range from 20 μM to 0.073 nM were prepared from a 2 mM solution of the test substance in DMSO....More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details
US Patent

TargetInterleukin-1 receptor-associated kinase 4(Human)
Bayer Pharma Aktiegesellschaft

US Patent
LigandChemical structure of BindingDB Monomer ID 414424BDBM414424(N-[2-(1-Glycoloylpiperidin-4-yl)-6-methoxy-2H-inda...)
Affinity DataIC50: 2nMAssay Description:For the assay, 11 different concentrations in the range from 20 μM to 0.073 nM were prepared from a 2 mM solution of the test substance in DMSO....More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details
US Patent

TargetInterleukin-1 receptor-associated kinase 4(Human)
Bayer Pharma Aktiegesellschaft

US Patent
LigandChemical structure of BindingDB Monomer ID 414428BDBM414428(N-[6-Methoxy-2-(1′-methyl-1,4′-bipiper...)
Affinity DataIC50: 2nMAssay Description:For the assay, 11 different concentrations in the range from 20 μM to 0.073 nM were prepared from a 2 mM solution of the test substance in DMSO....More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details
US Patent

TargetInterleukin-1 receptor-associated kinase 4(Human)
Bayer Pharma Aktiegesellschaft

US Patent
LigandChemical structure of BindingDB Monomer ID 414482BDBM414482(N-{6-Methoxy-2-[1-(2-methoxyethyl)piperidin-4-yl]-...)
Affinity DataIC50: 2nMAssay Description:For the assay, 11 different concentrations in the range from 20 μM to 0.073 nM were prepared from a 2 mM solution of the test substance in DMSO....More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details
US Patent

TargetInterleukin-1 receptor-associated kinase 4(Human)
Bayer Pharma Aktiegesellschaft

US Patent
LigandChemical structure of BindingDB Monomer ID 414457BDBM414457(6-(2-Hydroxypropan-2-yl)-N-[6-methoxy-2-(tetrahydr...)
Affinity DataIC50: 3nMAssay Description:For the assay, 11 different concentrations in the range from 20 μM to 0.073 nM were prepared from a 2 mM solution of the test substance in DMSO....More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details
US Patent

TargetInterleukin-1 receptor-associated kinase 4(Human)
Bayer Pharma Aktiegesellschaft

US Patent
LigandChemical structure of BindingDB Monomer ID 414433BDBM414433(N-{6-Methoxy-2-[1-(oxetan-3-yl)piperidin-4-yl]-2H-...)
Affinity DataIC50: 3nMAssay Description:For the assay, 11 different concentrations in the range from 20 μM to 0.073 nM were prepared from a 2 mM solution of the test substance in DMSO....More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details
US Patent

TargetInterleukin-1 receptor-associated kinase 4(Human)
Bayer Pharma Aktiegesellschaft

US Patent
LigandChemical structure of BindingDB Monomer ID 414434BDBM414434(N-[2-(1,1-Dioxidotetrahydro-2H-thiopyran-4-yl)-6-m...)
Affinity DataIC50: 3nMAssay Description:For the assay, 11 different concentrations in the range from 20 μM to 0.073 nM were prepared from a 2 mM solution of the test substance in DMSO....More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details
US Patent

TargetInterleukin-1 receptor-associated kinase 4(Human)
Bayer Pharma Aktiegesellschaft

US Patent
LigandChemical structure of BindingDB Monomer ID 414469BDBM414469(N-[6-(2-Hydroxypropan-2-yl)-2-(piperidin-4-yl)-2H-...)
Affinity DataIC50: 3nMAssay Description:For the assay, 11 different concentrations in the range from 20 μM to 0.073 nM were prepared from a 2 mM solution of the test substance in DMSO....More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details
US Patent

TargetInterleukin-1 receptor-associated kinase 4(Human)
Bayer Pharma Aktiegesellschaft

US Patent
LigandChemical structure of BindingDB Monomer ID 414442BDBM414442(N-[2-(1-Imino-1-oxidohexahydro-1λ4-thiopyran-...)
Affinity DataIC50: 3nMAssay Description:For the assay, 11 different concentrations in the range from 20 μM to 0.073 nM were prepared from a 2 mM solution of the test substance in DMSO....More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details
US Patent

TargetInterleukin-1 receptor-associated kinase 4(Human)
Bayer Pharma Aktiegesellschaft

US Patent
LigandChemical structure of BindingDB Monomer ID 414419BDBM414419(N-[6-Methoxy-2-(tetrahydro-2H-pyran-4-yl)-2H-indaz...)
Affinity DataIC50: 3nMAssay Description:For the assay, 11 different concentrations in the range from 20 μM to 0.073 nM were prepared from a 2 mM solution of the test substance in DMSO....More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details
US Patent

TargetInterleukin-1 receptor-associated kinase 4(Human)
Bayer Pharma Aktiegesellschaft

US Patent
LigandChemical structure of BindingDB Monomer ID 414480BDBM414480(2-[1-(3-Hydroxy-3-methylbutyl)piperidin-4-yl]-5-({...)
Affinity DataIC50: 4nMAssay Description:For the assay, 11 different concentrations in the range from 20 μM to 0.073 nM were prepared from a 2 mM solution of the test substance in DMSO....More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details
US Patent

TargetInterleukin-1 receptor-associated kinase 4(Human)
Bayer Pharma Aktiegesellschaft

US Patent
LigandChemical structure of BindingDB Monomer ID 414441BDBM414441(US10435396, Example 20)
Affinity DataIC50: 4nMAssay Description:For the assay, 11 different concentrations in the range from 20 μM to 0.073 nM were prepared from a 2 mM solution of the test substance in DMSO....More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details
US Patent

TargetInterleukin-1 receptor-associated kinase 4(Human)
Bayer Pharma Aktiegesellschaft

US Patent
LigandChemical structure of BindingDB Monomer ID 414468BDBM414468(N-[2-(1,1-Dioxidotetrahydro-2H-thiopyran-4-yl)-6-(...)
Affinity DataIC50: 5nMAssay Description:For the assay, 11 different concentrations in the range from 20 μM to 0.073 nM were prepared from a 2 mM solution of the test substance in DMSO....More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details
US Patent

TargetInterleukin-1 receptor-associated kinase 4(Human)
Bayer Pharma Aktiegesellschaft

US Patent
LigandChemical structure of BindingDB Monomer ID 414464BDBM414464(N-[6-(2-Hydroxypropan-2-yl)-2-(tetrahydro-2H-pyran...)
Affinity DataIC50: 6nMAssay Description:For the assay, 11 different concentrations in the range from 20 μM to 0.073 nM were prepared from a 2 mM solution of the test substance in DMSO....More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details
US Patent

TargetInterleukin-1 receptor-associated kinase 4(Human)
Bayer Pharma Aktiegesellschaft

US Patent
LigandChemical structure of BindingDB Monomer ID 414475BDBM414475(1-(Difluoromethyl)-N-[6-methoxy-2-(tetrahydro-2H-p...)
Affinity DataIC50: 6nMAssay Description:For the assay, 11 different concentrations in the range from 20 μM to 0.073 nM were prepared from a 2 mM solution of the test substance in DMSO....More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details
US Patent

TargetInterleukin-1 receptor-associated kinase 4(Human)
Bayer Pharma Aktiegesellschaft

US Patent
LigandChemical structure of BindingDB Monomer ID 414447BDBM414447(6-Amino-N-[6-methoxy-2-(tetrahydro-2H-pyran-4-yl)-...)
Affinity DataIC50: 6nMAssay Description:For the assay, 11 different concentrations in the range from 20 μM to 0.073 nM were prepared from a 2 mM solution of the test substance in DMSO....More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details
US Patent

TargetInterleukin-1 receptor-associated kinase 4(Human)
Bayer Pharma Aktiegesellschaft

US Patent
LigandChemical structure of BindingDB Monomer ID 414422BDBM414422(N-{6-Methoxy-2-[1-(2,2,2-trifluoroethyl)piperidin-...)
Affinity DataIC50: 7nMAssay Description:For the assay, 11 different concentrations in the range from 20 μM to 0.073 nM were prepared from a 2 mM solution of the test substance in DMSO....More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details
US Patent

TargetInterleukin-1 receptor-associated kinase 4(Human)
Bayer Pharma Aktiegesellschaft

US Patent
LigandChemical structure of BindingDB Monomer ID 414429BDBM414429(N-{2-[1-(Acetylsulphamoyl)piperidin-4-yl]-6-methox...)
Affinity DataIC50: 8nMAssay Description:For the assay, 11 different concentrations in the range from 20 μM to 0.073 nM were prepared from a 2 mM solution of the test substance in DMSO....More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details
US Patent

TargetInterleukin-1 receptor-associated kinase 4(Human)
Bayer Pharma Aktiegesellschaft

US Patent
LigandChemical structure of BindingDB Monomer ID 414440BDBM414440(rel-N-{6-Methoxy-2-[(1S,4S,5S)-2-methyl-2-azabicyc...)
Affinity DataIC50: 9nMAssay Description:For the assay, 11 different concentrations in the range from 20 μM to 0.073 nM were prepared from a 2 mM solution of the test substance in DMSO....More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details
US Patent

TargetInterleukin-1 receptor-associated kinase 4(Human)
Bayer Pharma Aktiegesellschaft

US Patent
LigandChemical structure of BindingDB Monomer ID 414458BDBM414458(N-[6-Methoxy-2-(tetrahydrofuran-3-yl)-2H-indazol-5...)
Affinity DataIC50: 10nMAssay Description:For the assay, 11 different concentrations in the range from 20 μM to 0.073 nM were prepared from a 2 mM solution of the test substance in DMSO....More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details
US Patent

TargetInterleukin-1 receptor-associated kinase 4(Human)
Bayer Pharma Aktiegesellschaft

US Patent
LigandChemical structure of BindingDB Monomer ID 414446BDBM414446(N-[6-Methoxy-2-(tetrahydro-2H-pyran-4-yl)-2H-indaz...)
Affinity DataIC50: 10nMAssay Description:For the assay, 11 different concentrations in the range from 20 μM to 0.073 nM were prepared from a 2 mM solution of the test substance in DMSO....More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details
US Patent

TargetInterleukin-1 receptor-associated kinase 4(Human)
Bayer Pharma Aktiegesellschaft

US Patent
LigandChemical structure of BindingDB Monomer ID 414463BDBM414463(Methyl 2-(tetrahydro-2H-pyran-4-yl)-5-({[6-(triflu...)
Affinity DataIC50: 11nMAssay Description:For the assay, 11 different concentrations in the range from 20 μM to 0.073 nM were prepared from a 2 mM solution of the test substance in DMSO....More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details
US Patent

TargetInterleukin-1 receptor-associated kinase 4(Human)
Bayer Pharma Aktiegesellschaft

US Patent
LigandChemical structure of BindingDB Monomer ID 414443BDBM414443(N-[6-Methoxy-2-(5-oxopyrrolidin-3-yl)-2H-indazol-5...)
Affinity DataIC50: 13nMAssay Description:For the assay, 11 different concentrations in the range from 20 μM to 0.073 nM were prepared from a 2 mM solution of the test substance in DMSO....More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details
US Patent

TargetInterleukin-1 receptor-associated kinase 4(Human)
Bayer Pharma Aktiegesellschaft

US Patent
LigandChemical structure of BindingDB Monomer ID 414467BDBM414467(N-{2-[(3S)-1,1-Dioxidotetrahydrothiophen-3-yl]-6-(...)
Affinity DataIC50: 16nMAssay Description:For the assay, 11 different concentrations in the range from 20 μM to 0.073 nM were prepared from a 2 mM solution of the test substance in DMSO....More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details
US Patent

TargetInterleukin-1 receptor-associated kinase 4(Human)
Bayer Pharma Aktiegesellschaft

US Patent
LigandChemical structure of BindingDB Monomer ID 414437BDBM414437(N-[6-(Cyclopropylmethoxy)-2-(1,1-dioxidotetrahydro...)
Affinity DataIC50: 20nMAssay Description:For the assay, 11 different concentrations in the range from 20 μM to 0.073 nM were prepared from a 2 mM solution of the test substance in DMSO....More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details
US Patent

TargetInterleukin-1 receptor-associated kinase 4(Human)
Bayer Pharma Aktiegesellschaft

US Patent
LigandChemical structure of BindingDB Monomer ID 414461BDBM414461(N-[6-Chloro-2-(tetrahydro-2H-pyran-4-yl)-2H-indazo...)
Affinity DataIC50: 22nMAssay Description:For the assay, 11 different concentrations in the range from 20 μM to 0.073 nM were prepared from a 2 mM solution of the test substance in DMSO....More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details
US Patent

TargetInterleukin-1 receptor-associated kinase 4(Human)
Bayer Pharma Aktiegesellschaft

US Patent
LigandChemical structure of BindingDB Monomer ID 414465BDBM414465(N-{6-(2-Hydroxypropan-2-yl)-2-[(3S)-tetrahydrofura...)
Affinity DataIC50: 28nMAssay Description:For the assay, 11 different concentrations in the range from 20 μM to 0.073 nM were prepared from a 2 mM solution of the test substance in DMSO....More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details
US Patent

TargetInterleukin-1 receptor-associated kinase 4(Human)
Bayer Pharma Aktiegesellschaft

US Patent
LigandChemical structure of BindingDB Monomer ID 414466BDBM414466(N-{6-(2-Hydroxypropan-2-yl)-2-[(3R)-tetrahydrofura...)
Affinity DataIC50: 31nMAssay Description:For the assay, 11 different concentrations in the range from 20 μM to 0.073 nM were prepared from a 2 mM solution of the test substance in DMSO....More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details
US Patent

TargetInterleukin-1 receptor-associated kinase 4(Human)
Bayer Pharma Aktiegesellschaft

US Patent
LigandChemical structure of BindingDB Monomer ID 414462BDBM414462(N-[6-Chloro-2-(1,1-dioxidotetrahydro-2H-thiopyran-...)
Affinity DataIC50: 34nMAssay Description:For the assay, 11 different concentrations in the range from 20 μM to 0.073 nM were prepared from a 2 mM solution of the test substance in DMSO....More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details
US Patent

TargetInterleukin-1 receptor-associated kinase 4(Human)
Bayer Pharma Aktiegesellschaft

US Patent
LigandChemical structure of BindingDB Monomer ID 414459BDBM414459(N-[6-Chloro-2-(tetrahydro-2H-pyran-4-yl)-2H-indazo...)
Affinity DataIC50: 47nMAssay Description:For the assay, 11 different concentrations in the range from 20 μM to 0.073 nM were prepared from a 2 mM solution of the test substance in DMSO....More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details
US Patent

TargetInterleukin-1 receptor-associated kinase 4(Human)
Bayer Pharma Aktiegesellschaft

US Patent
LigandChemical structure of BindingDB Monomer ID 414470BDBM414470(N-[6-Methoxy-2-(tetrahydro-2H-pyran-4-yl)-2H-indaz...)
Affinity DataIC50: 65nMAssay Description:For the assay, 11 different concentrations in the range from 20 μM to 0.073 nM were prepared from a 2 mM solution of the test substance in DMSO....More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details
US Patent

TargetInterleukin-1 receptor-associated kinase 4(Human)
Bayer Pharma Aktiegesellschaft

US Patent
LigandChemical structure of BindingDB Monomer ID 414478BDBM414478(2-(Piperidin-4-yl)-5-({[6-(trifluoromethyl)pyridin...)
Affinity DataIC50: 75nMAssay Description:For the assay, 11 different concentrations in the range from 20 μM to 0.073 nM were prepared from a 2 mM solution of the test substance in DMSO....More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details
US Patent

TargetInterleukin-1 receptor-associated kinase 4(Human)
Bayer Pharma Aktiegesellschaft

US Patent
LigandChemical structure of BindingDB Monomer ID 414456BDBM414456(2-Isopropyl-N-[6-methoxy-2-(tetrahydro-2H-pyran-4-...)
Affinity DataIC50: 111nMAssay Description:For the assay, 11 different concentrations in the range from 20 μM to 0.073 nM were prepared from a 2 mM solution of the test substance in DMSO....More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details
US Patent

TargetInterleukin-1 receptor-associated kinase 4(Human)
Bayer Pharma Aktiegesellschaft

US Patent
LigandChemical structure of BindingDB Monomer ID 414474BDBM414474(N-[6-Chloro-2-(tetrahydro-2H-pyran-4-yl)-2H-indazo...)
Affinity DataIC50: 496nMAssay Description:For the assay, 11 different concentrations in the range from 20 μM to 0.073 nM were prepared from a 2 mM solution of the test substance in DMSO....More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details
US Patent

TargetInterleukin-1 receptor-associated kinase 4(Human)
Bayer Pharma Aktiegesellschaft

US Patent
LigandChemical structure of BindingDB Monomer ID 414471BDBM414471(N-[6-Methoxy-2-(tetrahydro-2H-pyran-4-yl)-2H-indaz...)
Affinity DataIC50: 691nMAssay Description:For the assay, 11 different concentrations in the range from 20 μM to 0.073 nM were prepared from a 2 mM solution of the test substance in DMSO....More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details
US Patent

TargetInterleukin-1 receptor-associated kinase 4(Human)
Bayer Pharma Aktiegesellschaft

US Patent
LigandChemical structure of BindingDB Monomer ID 414472BDBM414472(N-[6-Methoxy-2-(tetrahydro-2H-pyran-4-yl)-2H-indaz...)
Affinity DataIC50: 3.78E+3nMAssay Description:For the assay, 11 different concentrations in the range from 20 μM to 0.073 nM were prepared from a 2 mM solution of the test substance in DMSO....More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details
US Patent