Compile Data Set for Download or QSAR
Report error Found 152 Enz. Inhib. hit(s) with all data for entry = 8726
TargetTyrosine-protein kinase BTK(Human)
Bristol-Myers Squibb

US Patent
LigandChemical structure of BindingDB Monomer ID 230115BDBM230115(US9334290, 45 | US9334290, 44 | US10106559, Exampl...)
Affinity DataIC50: 0.180nMAssay Description:To V-bottom 384-well plates were added test compounds, human recombinant Btk (1 nM, Invitrogen Corporation), fluoresceinated peptide (1.5 μM), A...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details
US Patent

TargetTyrosine-protein kinase BTK(Human)
Bristol-Myers Squibb

US Patent
LigandChemical structure of BindingDB Monomer ID 230106BDBM230106(US9334290, 30 | US10106559, Example 31 | US9850258...)
Affinity DataIC50: 0.190nMAssay Description:To V-bottom 384-well plates were added test compounds, human recombinant Btk (1 nM, Invitrogen Corporation), fluoresceinated peptide (1.5 μM), A...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details
US Patent

TargetTyrosine-protein kinase BTK(Human)
Bristol-Myers Squibb

US Patent
LigandChemical structure of BindingDB Monomer ID 230112BDBM230112(US9334290, 40 | US10106559, Example 41 | US9850258...)
Affinity DataIC50: 0.200nMAssay Description:To V-bottom 384-well plates were added test compounds, human recombinant Btk (1 nM, Invitrogen Corporation), fluoresceinated peptide (1.5 μM), A...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details
US Patent

TargetTyrosine-protein kinase BTK(Human)
Bristol-Myers Squibb

US Patent
LigandChemical structure of BindingDB Monomer ID 230106BDBM230106(US9334290, 30 | US10106559, Example 31 | US9850258...)
Affinity DataIC50: 0.220nMAssay Description:To V-bottom 384-well plates were added test compounds, human recombinant Btk (1 nM, Invitrogen Corporation), fluoresceinated peptide (1.5 μM), A...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details
US Patent

TargetTyrosine-protein kinase BTK(Human)
Bristol-Myers Squibb

US Patent
LigandChemical structure of BindingDB Monomer ID 230108BDBM230108(US9334290, 35 | US9334290, 34 | US10106559, Exampl...)
Affinity DataIC50: 0.25nMAssay Description:To V-bottom 384-well plates were added test compounds, human recombinant Btk (1 nM, Invitrogen Corporation), fluoresceinated peptide (1.5 μM), A...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details
US Patent

TargetTyrosine-protein kinase BTK(Human)
Bristol-Myers Squibb

US Patent
LigandChemical structure of BindingDB Monomer ID 230128BDBM230128(US9334290, 57 | US10106559, Example 57 | US9850258...)
Affinity DataIC50: 0.25nMAssay Description:To V-bottom 384-well plates were added test compounds, human recombinant Btk (1 nM, Invitrogen Corporation), fluoresceinated peptide (1.5 μM), A...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details
US Patent

TargetTyrosine-protein kinase BTK(Human)
Bristol-Myers Squibb

US Patent
LigandChemical structure of BindingDB Monomer ID 230107BDBM230107(US9334290, 32 | US10106559, Example 33 | US9850258...)
Affinity DataIC50: 0.260nMAssay Description:To V-bottom 384-well plates were added test compounds, human recombinant Btk (1 nM, Invitrogen Corporation), fluoresceinated peptide (1.5 μM), A...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details
US Patent

TargetTyrosine-protein kinase BTK(Human)
Bristol-Myers Squibb

US Patent
LigandChemical structure of BindingDB Monomer ID 230120BDBM230120(US9334290, 50 | US9334290, 73 | US9334290, 49 | US...)
Affinity DataIC50: 0.260nMAssay Description:To V-bottom 384-well plates were added test compounds, human recombinant Btk (1 nM, Invitrogen Corporation), fluoresceinated peptide (1.5 μM), A...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details
US Patent

TargetTyrosine-protein kinase BTK(Human)
Bristol-Myers Squibb

US Patent
LigandChemical structure of BindingDB Monomer ID 230126BDBM230126(US9334290, 56 | US9334290, 55 | US10106559, Exampl...)
Affinity DataIC50: 0.260nMAssay Description:To V-bottom 384-well plates were added test compounds, human recombinant Btk (1 nM, Invitrogen Corporation), fluoresceinated peptide (1.5 μM), A...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details
US Patent

TargetTyrosine-protein kinase BTK(Human)
Bristol-Myers Squibb

US Patent
LigandChemical structure of BindingDB Monomer ID 230093BDBM230093(US9334290, 15 | US10106559, Example 16 | US9850258...)
Affinity DataIC50: 0.270nMAssay Description:To V-bottom 384-well plates were added test compounds, human recombinant Btk (1 nM, Invitrogen Corporation), fluoresceinated peptide (1.5 μM), A...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details
US Patent

TargetTyrosine-protein kinase BTK(Human)
Bristol-Myers Squibb

US Patent
LigandChemical structure of BindingDB Monomer ID 230108BDBM230108(US9334290, 35 | US9334290, 34 | US10106559, Exampl...)
Affinity DataIC50: 0.280nMAssay Description:To V-bottom 384-well plates were added test compounds, human recombinant Btk (1 nM, Invitrogen Corporation), fluoresceinated peptide (1.5 μM), A...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details
US Patent

TargetTyrosine-protein kinase BTK(Human)
Bristol-Myers Squibb

US Patent
LigandChemical structure of BindingDB Monomer ID 230122BDBM230122(US9334290, 51 | US10106559, Example 51 | US9850258...)
Affinity DataIC50: 0.300nMAssay Description:To V-bottom 384-well plates were added test compounds, human recombinant Btk (1 nM, Invitrogen Corporation), fluoresceinated peptide (1.5 μM), A...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details
US Patent

TargetTyrosine-protein kinase BTK(Human)
Bristol-Myers Squibb

US Patent
LigandChemical structure of BindingDB Monomer ID 230111BDBM230111(US9334290, 38 | US10106559, Example 39 | US9850258...)
Affinity DataIC50: 0.310nMAssay Description:To V-bottom 384-well plates were added test compounds, human recombinant Btk (1 nM, Invitrogen Corporation), fluoresceinated peptide (1.5 μM), A...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details
US Patent

TargetTyrosine-protein kinase BTK(Human)
Bristol-Myers Squibb

US Patent
LigandChemical structure of BindingDB Monomer ID 230120BDBM230120(US9334290, 50 | US9334290, 73 | US9334290, 49 | US...)
Affinity DataIC50: 0.320nMAssay Description:To V-bottom 384-well plates were added test compounds, human recombinant Btk (1 nM, Invitrogen Corporation), fluoresceinated peptide (1.5 μM), A...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details
US Patent

TargetTyrosine-protein kinase BTK(Human)
Bristol-Myers Squibb

US Patent
LigandChemical structure of BindingDB Monomer ID 230099BDBM230099(US9334290, 24 | US9334290, 23 | US10106559, Exampl...)
Affinity DataIC50: 0.330nMAssay Description:To V-bottom 384-well plates were added test compounds, human recombinant Btk (1 nM, Invitrogen Corporation), fluoresceinated peptide (1.5 μM), A...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details
US Patent

TargetTyrosine-protein kinase BTK(Human)
Bristol-Myers Squibb

US Patent
LigandChemical structure of BindingDB Monomer ID 230088BDBM230088(US9334290, 10 | US10106559, Example 48 | US9850258...)
Affinity DataIC50: 0.330nMAssay Description:To V-bottom 384-well plates were added test compounds, human recombinant Btk (1 nM, Invitrogen Corporation), fluoresceinated peptide (1.5 μM), A...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details
US Patent

TargetTyrosine-protein kinase BTK(Human)
Bristol-Myers Squibb

US Patent
LigandChemical structure of BindingDB Monomer ID 230097BDBM230097(US9334290, 20 | US10106559, Example 22 | US9850258...)
Affinity DataIC50: 0.330nMAssay Description:To V-bottom 384-well plates were added test compounds, human recombinant Btk (1 nM, Invitrogen Corporation), fluoresceinated peptide (1.5 μM), A...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details
US Patent

TargetTyrosine-protein kinase BTK(Human)
Bristol-Myers Squibb

US Patent
LigandChemical structure of BindingDB Monomer ID 294109BDBM294109(US10106559, Example 66 | US9850258, Example 66 | U...)
Affinity DataIC50: 0.340nMAssay Description:To V-bottom 384-well plates were added test compounds, human recombinant Btk (1 nM, Invitrogen Corporation), fluoresceinated peptide (1.5 μM), A...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details
US Patent

TargetTyrosine-protein kinase BTK(Human)
Bristol-Myers Squibb

US Patent
LigandChemical structure of BindingDB Monomer ID 230133BDBM230133(US9334290, 65 | US9334290, 64 | US10106559, Exampl...)
Affinity DataIC50: 0.340nMAssay Description:To V-bottom 384-well plates were added test compounds, human recombinant Btk (1 nM, Invitrogen Corporation), fluoresceinated peptide (1.5 μM), A...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details
US Patent

TargetTyrosine-protein kinase BTK(Human)
Bristol-Myers Squibb

US Patent
LigandChemical structure of BindingDB Monomer ID 230111BDBM230111(US9334290, 38 | US10106559, Example 39 | US9850258...)
Affinity DataIC50: 0.340nMAssay Description:To V-bottom 384-well plates were added test compounds, human recombinant Btk (1 nM, Invitrogen Corporation), fluoresceinated peptide (1.5 μM), A...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details
US Patent

TargetTyrosine-protein kinase BTK(Human)
Bristol-Myers Squibb

US Patent
LigandChemical structure of BindingDB Monomer ID 230124BDBM230124(US9334290, 54 | US9334290, 53 | US10106559, Exampl...)
Affinity DataIC50: 0.350nMAssay Description:To V-bottom 384-well plates were added test compounds, human recombinant Btk (1 nM, Invitrogen Corporation), fluoresceinated peptide (1.5 μM), A...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details
US Patent

TargetTyrosine-protein kinase BTK(Human)
Bristol-Myers Squibb

US Patent
LigandChemical structure of BindingDB Monomer ID 230118BDBM230118(US9334290, 47 | US10106559, Example 47 | US9850258...)
Affinity DataIC50: 0.350nMAssay Description:To V-bottom 384-well plates were added test compounds, human recombinant Btk (1 nM, Invitrogen Corporation), fluoresceinated peptide (1.5 μM), A...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details
US Patent

TargetTyrosine-protein kinase BTK(Human)
Bristol-Myers Squibb

US Patent
LigandChemical structure of BindingDB Monomer ID 230089BDBM230089(US9334290, 11 | US10106559, Example 12 | US9850258...)
Affinity DataIC50: 0.400nMAssay Description:To V-bottom 384-well plates were added test compounds, human recombinant Btk (1 nM, Invitrogen Corporation), fluoresceinated peptide (1.5 μM), A...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details
US Patent

TargetTyrosine-protein kinase BTK(Human)
Bristol-Myers Squibb

US Patent
LigandChemical structure of BindingDB Monomer ID 230104BDBM230104(US9334290, 28 | US10106559, Example 62 | US9850258...)
Affinity DataIC50: 0.410nMAssay Description:To V-bottom 384-well plates were added test compounds, human recombinant Btk (1 nM, Invitrogen Corporation), fluoresceinated peptide (1.5 μM), A...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details
US Patent

TargetTyrosine-protein kinase BTK(Human)
Bristol-Myers Squibb

US Patent
LigandChemical structure of BindingDB Monomer ID 230140BDBM230140(US9334290, 71 | US10106559, Example 71 | US9850258...)
Affinity DataIC50: 0.410nMAssay Description:To V-bottom 384-well plates were added test compounds, human recombinant Btk (1 nM, Invitrogen Corporation), fluoresceinated peptide (1.5 μM), A...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details
US Patent

TargetTyrosine-protein kinase BTK(Human)
Bristol-Myers Squibb

US Patent
LigandChemical structure of BindingDB Monomer ID 230099BDBM230099(US9334290, 24 | US9334290, 23 | US10106559, Exampl...)
Affinity DataIC50: 0.440nMAssay Description:To V-bottom 384-well plates were added test compounds, human recombinant Btk (1 nM, Invitrogen Corporation), fluoresceinated peptide (1.5 μM), A...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details
US Patent

TargetTyrosine-protein kinase BTK(Human)
Bristol-Myers Squibb

US Patent
LigandChemical structure of BindingDB Monomer ID 230094BDBM230094(US9334290, 18 | US9334290, 17 | US10106559, Exampl...)
Affinity DataIC50: 0.450nMAssay Description:To V-bottom 384-well plates were added test compounds, human recombinant Btk (1 nM, Invitrogen Corporation), fluoresceinated peptide (1.5 μM), A...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details
US Patent

TargetTyrosine-protein kinase BTK(Human)
Bristol-Myers Squibb

US Patent
LigandChemical structure of BindingDB Monomer ID 230132BDBM230132(US9334290, 63 | US10106559, Example 63 | US9850258...)
Affinity DataIC50: 0.450nMAssay Description:To V-bottom 384-well plates were added test compounds, human recombinant Btk (1 nM, Invitrogen Corporation), fluoresceinated peptide (1.5 μM), A...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details
US Patent

TargetTyrosine-protein kinase BTK(Human)
Bristol-Myers Squibb

US Patent
LigandChemical structure of BindingDB Monomer ID 230115BDBM230115(US9334290, 45 | US9334290, 44 | US10106559, Exampl...)
Affinity DataIC50: 0.450nMAssay Description:To V-bottom 384-well plates were added test compounds, human recombinant Btk (1 nM, Invitrogen Corporation), fluoresceinated peptide (1.5 μM), A...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details
US Patent

TargetTyrosine-protein kinase BTK(Human)
Bristol-Myers Squibb

US Patent
LigandChemical structure of BindingDB Monomer ID 230112BDBM230112(US9334290, 40 | US10106559, Example 41 | US9850258...)
Affinity DataIC50: 0.460nMAssay Description:To V-bottom 384-well plates were added test compounds, human recombinant Btk (1 nM, Invitrogen Corporation), fluoresceinated peptide (1.5 μM), A...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details
US Patent

TargetTyrosine-protein kinase BTK(Human)
Bristol-Myers Squibb

US Patent
LigandChemical structure of BindingDB Monomer ID 230133BDBM230133(US9334290, 65 | US9334290, 64 | US10106559, Exampl...)
Affinity DataIC50: 0.460nMAssay Description:To V-bottom 384-well plates were added test compounds, human recombinant Btk (1 nM, Invitrogen Corporation), fluoresceinated peptide (1.5 μM), A...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details
US Patent

TargetTyrosine-protein kinase BTK(Human)
Bristol-Myers Squibb

US Patent
LigandChemical structure of BindingDB Monomer ID 230097BDBM230097(US9334290, 20 | US10106559, Example 22 | US9850258...)
Affinity DataIC50: 0.460nMAssay Description:To V-bottom 384-well plates were added test compounds, human recombinant Btk (1 nM, Invitrogen Corporation), fluoresceinated peptide (1.5 μM), A...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details
US Patent

TargetTyrosine-protein kinase BTK(Human)
Bristol-Myers Squibb

US Patent
LigandChemical structure of BindingDB Monomer ID 230113BDBM230113(US9334290, 43 | US9334290, 42 | US10106559, Exampl...)
Affinity DataIC50: 0.470nMAssay Description:To V-bottom 384-well plates were added test compounds, human recombinant Btk (1 nM, Invitrogen Corporation), fluoresceinated peptide (1.5 μM), A...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details
US Patent

TargetTyrosine-protein kinase BTK(Human)
Bristol-Myers Squibb

US Patent
LigandChemical structure of BindingDB Monomer ID 230094BDBM230094(US9334290, 18 | US9334290, 17 | US10106559, Exampl...)
Affinity DataIC50: 0.480nMAssay Description:To V-bottom 384-well plates were added test compounds, human recombinant Btk (1 nM, Invitrogen Corporation), fluoresceinated peptide (1.5 μM), A...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details
US Patent

TargetTyrosine-protein kinase BTK(Human)
Bristol-Myers Squibb

US Patent
LigandChemical structure of BindingDB Monomer ID 230097BDBM230097(US9334290, 20 | US10106559, Example 22 | US9850258...)
Affinity DataIC50: 0.480nMAssay Description:To V-bottom 384-well plates were added test compounds, human recombinant Btk (1 nM, Invitrogen Corporation), fluoresceinated peptide (1.5 μM), A...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details
US Patent

TargetTyrosine-protein kinase BTK(Human)
Bristol-Myers Squibb

US Patent
LigandChemical structure of BindingDB Monomer ID 230136BDBM230136(US9334290, 67 | US10106559, Example 67 | US9850258...)
Affinity DataIC50: 0.490nMAssay Description:To V-bottom 384-well plates were added test compounds, human recombinant Btk (1 nM, Invitrogen Corporation), fluoresceinated peptide (1.5 μM), A...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details
US Patent

TargetTyrosine-protein kinase BTK(Human)
Bristol-Myers Squibb

US Patent
LigandChemical structure of BindingDB Monomer ID 230141BDBM230141(US9334290, 72 | US10106559, Example 72 | US9850258...)
Affinity DataIC50: 0.490nMAssay Description:To V-bottom 384-well plates were added test compounds, human recombinant Btk (1 nM, Invitrogen Corporation), fluoresceinated peptide (1.5 μM), A...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details
US Patent

TargetTyrosine-protein kinase BTK(Human)
Bristol-Myers Squibb

US Patent
LigandChemical structure of BindingDB Monomer ID 230104BDBM230104(US9334290, 28 | US10106559, Example 62 | US9850258...)
Affinity DataIC50: 0.540nMAssay Description:To V-bottom 384-well plates were added test compounds, human recombinant Btk (1 nM, Invitrogen Corporation), fluoresceinated peptide (1.5 μM), A...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details
US Patent

TargetTyrosine-protein kinase BTK(Human)
Bristol-Myers Squibb

US Patent
LigandChemical structure of BindingDB Monomer ID 230107BDBM230107(US9334290, 32 | US10106559, Example 33 | US9850258...)
Affinity DataIC50: 0.550nMAssay Description:To V-bottom 384-well plates were added test compounds, human recombinant Btk (1 nM, Invitrogen Corporation), fluoresceinated peptide (1.5 μM), A...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details
US Patent

TargetTyrosine-protein kinase BTK(Human)
Bristol-Myers Squibb

US Patent
LigandChemical structure of BindingDB Monomer ID 230137BDBM230137(US9334290, 69 | US9334290, 68 | US10106559, Exampl...)
Affinity DataIC50: 0.560nMAssay Description:To V-bottom 384-well plates were added test compounds, human recombinant Btk (1 nM, Invitrogen Corporation), fluoresceinated peptide (1.5 μM), A...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details
US Patent

TargetTyrosine-protein kinase BTK(Human)
Bristol-Myers Squibb

US Patent
LigandChemical structure of BindingDB Monomer ID 230094BDBM230094(US9334290, 18 | US9334290, 17 | US10106559, Exampl...)
Affinity DataIC50: 0.590nMAssay Description:To V-bottom 384-well plates were added test compounds, human recombinant Btk (1 nM, Invitrogen Corporation), fluoresceinated peptide (1.5 μM), A...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details
US Patent

TargetTyrosine-protein kinase BTK(Human)
Bristol-Myers Squibb

US Patent
LigandChemical structure of BindingDB Monomer ID 230139BDBM230139(US9334290, 70 | US10106559, Example 70 | US9850258...)
Affinity DataIC50: 0.590nMAssay Description:To V-bottom 384-well plates were added test compounds, human recombinant Btk (1 nM, Invitrogen Corporation), fluoresceinated peptide (1.5 μM), A...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details
US Patent

TargetTyrosine-protein kinase BTK(Human)
Bristol-Myers Squibb

US Patent
LigandChemical structure of BindingDB Monomer ID 230126BDBM230126(US9334290, 56 | US9334290, 55 | US10106559, Exampl...)
Affinity DataIC50: 0.620nMAssay Description:To V-bottom 384-well plates were added test compounds, human recombinant Btk (1 nM, Invitrogen Corporation), fluoresceinated peptide (1.5 μM), A...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details
US Patent

TargetTyrosine-protein kinase BTK(Human)
Bristol-Myers Squibb

US Patent
LigandChemical structure of BindingDB Monomer ID 230087BDBM230087(US9334290, 9 | US10106559, Example 9 | US9850258, ...)
Affinity DataIC50: 0.620nMAssay Description:To V-bottom 384-well plates were added test compounds, human recombinant Btk (1 nM, Invitrogen Corporation), fluoresceinated peptide (1.5 μM), A...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details
US Patent

TargetTyrosine-protein kinase BTK(Human)
Bristol-Myers Squibb

US Patent
LigandChemical structure of BindingDB Monomer ID 230094BDBM230094(US9334290, 18 | US9334290, 17 | US10106559, Exampl...)
Affinity DataIC50: 0.650nMAssay Description:To V-bottom 384-well plates were added test compounds, human recombinant Btk (1 nM, Invitrogen Corporation), fluoresceinated peptide (1.5 μM), A...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details
US Patent

TargetTyrosine-protein kinase BTK(Human)
Bristol-Myers Squibb

US Patent
LigandChemical structure of BindingDB Monomer ID 230086BDBM230086(US9334290, 8 | US10106559, Example 8 | US9850258, ...)
Affinity DataIC50: 0.650nMAssay Description:To V-bottom 384-well plates were added test compounds, human recombinant Btk (1 nM, Invitrogen Corporation), fluoresceinated peptide (1.5 μM), A...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details
US Patent

TargetTyrosine-protein kinase BTK(Human)
Bristol-Myers Squibb

US Patent
LigandChemical structure of BindingDB Monomer ID 230105BDBM230105(US9334290, 29 | US10106559, Example 29 | US9850258...)
Affinity DataIC50: 0.660nMAssay Description:To V-bottom 384-well plates were added test compounds, human recombinant Btk (1 nM, Invitrogen Corporation), fluoresceinated peptide (1.5 μM), A...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details
US Patent

TargetTyrosine-protein kinase BTK(Human)
Bristol-Myers Squibb

US Patent
LigandChemical structure of BindingDB Monomer ID 230120BDBM230120(US9334290, 50 | US9334290, 73 | US9334290, 49 | US...)
Affinity DataIC50: 0.770nMAssay Description:To V-bottom 384-well plates were added test compounds, human recombinant Btk (1 nM, Invitrogen Corporation), fluoresceinated peptide (1.5 μM), A...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details
US Patent

TargetTyrosine-protein kinase BTK(Human)
Bristol-Myers Squibb

US Patent
LigandChemical structure of BindingDB Monomer ID 230094BDBM230094(US9334290, 18 | US9334290, 17 | US10106559, Exampl...)
Affinity DataIC50: 0.790nMAssay Description:To V-bottom 384-well plates were added test compounds, human recombinant Btk (1 nM, Invitrogen Corporation), fluoresceinated peptide (1.5 μM), A...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details
US Patent

TargetTyrosine-protein kinase BTK(Human)
Bristol-Myers Squibb

US Patent
LigandChemical structure of BindingDB Monomer ID 230085BDBM230085(US9334290, 7 | US10106559, Example 7 | US9850258, ...)
Affinity DataIC50: 0.810nMAssay Description:To V-bottom 384-well plates were added test compounds, human recombinant Btk (1 nM, Invitrogen Corporation), fluoresceinated peptide (1.5 μM), A...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details
US Patent

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