Compile Data Set for Download or QSAR
Report error Found 40 Enz. Inhib. hit(s) with all data for entry = 8935
TargetFibroblast growth factor receptor 1(Human)
Principia Biopharma

US Patent
LigandChemical structure of BindingDB Monomer ID 430237BDBM430237(2-(3-(2-(6-(2,6-dichloro-3,5-dimethoxyphenyl)-2-(m...)
Affinity DataIC50: 0.600nMAssay Description:A Caliper-based kinase assay (Caliper Life Sciences, Hopkinton, Mass.) was used to measure inhibition of FGFR family (FGFR1, FGFR2, FGFR3, FGFR4) kin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/9/2020
Entry Details
US Patent

TargetFibroblast growth factor receptor 1(Human)
Principia Biopharma

US Patent
LigandChemical structure of BindingDB Monomer ID 430235BDBM430235(2-(4-(3-(6-(2,6-dichloro-3,5-dimethoxyphenyl)-2-(m...)
Affinity DataIC50: 0.700nMAssay Description:A Caliper-based kinase assay (Caliper Life Sciences, Hopkinton, Mass.) was used to measure inhibition of FGFR family (FGFR1, FGFR2, FGFR3, FGFR4) kin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/9/2020
Entry Details
US Patent

TargetFibroblast growth factor receptor 1(Human)
Principia Biopharma

US Patent
LigandChemical structure of BindingDB Monomer ID 430242BDBM430242(4-amino-N-(6-(2-(6-(2-chloro-3,5-dimethoxyphenyl)-...)
Affinity DataIC50: 0.700nMAssay Description:A Caliper-based kinase assay (Caliper Life Sciences, Hopkinton, Mass.) was used to measure inhibition of FGFR family (FGFR1, FGFR2, FGFR3, FGFR4) kin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/9/2020
Entry Details
US Patent

TargetFibroblast growth factor receptor 1(Human)
Principia Biopharma

US Patent
LigandChemical structure of BindingDB Monomer ID 430248BDBM430248(4-amino-N-(5-(2-(6-(2-chloro-3,5-dimethoxyphenyl)-...)
Affinity DataIC50: 1.40nMAssay Description:A Caliper-based kinase assay (Caliper Life Sciences, Hopkinton, Mass.) was used to measure inhibition of FGFR family (FGFR1, FGFR2, FGFR3, FGFR4) kin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/9/2020
Entry Details
US Patent

TargetFibroblast growth factor receptor 1(Human)
Principia Biopharma

US Patent
LigandChemical structure of BindingDB Monomer ID 430230BDBM430230(2-(3-(2-(6-(2,6-dichloro-3,5-dimethoxyphenyl)-2-(m...)
Affinity DataIC50: 1.5nMAssay Description:A Caliper-based kinase assay (Caliper Life Sciences, Hopkinton, Mass.) was used to measure inhibition of FGFR family (FGFR1, FGFR2, FGFR3, FGFR4) kin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/9/2020
Entry Details
US Patent

TargetFibroblast growth factor receptor 1(Human)
Principia Biopharma

US Patent
LigandChemical structure of BindingDB Monomer ID 430244BDBM430244(2-cyano-N-(4-(2-(6-(2,6-dichloro-3,5-dimethoxyphen...)
Affinity DataIC50: 1.5nMAssay Description:A Caliper-based kinase assay (Caliper Life Sciences, Hopkinton, Mass.) was used to measure inhibition of FGFR family (FGFR1, FGFR2, FGFR3, FGFR4) kin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/9/2020
Entry Details
US Patent

TargetFibroblast growth factor receptor 1(Human)
Principia Biopharma

US Patent
LigandChemical structure of BindingDB Monomer ID 430247BDBM430247(2-cyano-N-(3-((6-(2,6-dichloro-3,5-dimethoxyphenyl...)
Affinity DataIC50: 1.90nMAssay Description:A Caliper-based kinase assay (Caliper Life Sciences, Hopkinton, Mass.) was used to measure inhibition of FGFR family (FGFR1, FGFR2, FGFR3, FGFR4) kin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/9/2020
Entry Details
US Patent

TargetFibroblast growth factor receptor 1(Human)
Principia Biopharma

US Patent
LigandChemical structure of BindingDB Monomer ID 430262BDBM430262(N-(4-(2-(6-(2-chloro-3,5-dimethoxyphenyl)-2-(methy...)
Affinity DataIC50: 1.90nMAssay Description:A Caliper-based kinase assay (Caliper Life Sciences, Hopkinton, Mass.) was used to measure inhibition of FGFR family (FGFR1, FGFR2, FGFR3, FGFR4) kin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/9/2020
Entry Details
US Patent

TargetFibroblast growth factor receptor 1(Human)
Principia Biopharma

US Patent
LigandChemical structure of BindingDB Monomer ID 430245BDBM430245(4-amino-N-(4-(2-(6-(2-chloro-3,5-dimethoxyphenyl)-...)
Affinity DataIC50: 2nMAssay Description:A Caliper-based kinase assay (Caliper Life Sciences, Hopkinton, Mass.) was used to measure inhibition of FGFR family (FGFR1, FGFR2, FGFR3, FGFR4) kin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/9/2020
Entry Details
US Patent

TargetFibroblast growth factor receptor 1(Human)
Principia Biopharma

US Patent
LigandChemical structure of BindingDB Monomer ID 430240BDBM430240(N-(4-(2-(6-(2-chloro-3,5-dimethoxyphenyl)-2-(methy...)
Affinity DataIC50: 2.90nMAssay Description:A Caliper-based kinase assay (Caliper Life Sciences, Hopkinton, Mass.) was used to measure inhibition of FGFR family (FGFR1, FGFR2, FGFR3, FGFR4) kin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/9/2020
Entry Details
US Patent

TargetFibroblast growth factor receptor 1(Human)
Principia Biopharma

US Patent
LigandChemical structure of BindingDB Monomer ID 430257BDBM430257(N-(4-(2-(6-(2-chloro-3,5-dimethoxyphenyl)-2-(methy...)
Affinity DataIC50: 3.60nMAssay Description:A Caliper-based kinase assay (Caliper Life Sciences, Hopkinton, Mass.) was used to measure inhibition of FGFR family (FGFR1, FGFR2, FGFR3, FGFR4) kin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/9/2020
Entry Details
US Patent

TargetFibroblast growth factor receptor 1(Human)
Principia Biopharma

US Patent
LigandChemical structure of BindingDB Monomer ID 430265BDBM430265(N-(4-(2-(6-(2-chloro-3,5-dimethoxyphenyl)-2-(methy...)
Affinity DataIC50: 3.80nMAssay Description:A Caliper-based kinase assay (Caliper Life Sciences, Hopkinton, Mass.) was used to measure inhibition of FGFR family (FGFR1, FGFR2, FGFR3, FGFR4) kin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/9/2020
Entry Details
US Patent

TargetFibroblast growth factor receptor 1(Human)
Principia Biopharma

US Patent
LigandChemical structure of BindingDB Monomer ID 430251BDBM430251(4-amino-N-(3-(2-(6-(2-chloro-3,5-dimethoxyphenyl)-...)
Affinity DataIC50: 4.5nMAssay Description:A Caliper-based kinase assay (Caliper Life Sciences, Hopkinton, Mass.) was used to measure inhibition of FGFR family (FGFR1, FGFR2, FGFR3, FGFR4) kin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/9/2020
Entry Details
US Patent

TargetFibroblast growth factor receptor 1(Human)
Principia Biopharma

US Patent
LigandChemical structure of BindingDB Monomer ID 430255BDBM430255(N-(3-(2-(6-(2-chloro-3,5-dimethoxyphenyl)-2-(methy...)
Affinity DataIC50: 4.60nMAssay Description:A Caliper-based kinase assay (Caliper Life Sciences, Hopkinton, Mass.) was used to measure inhibition of FGFR family (FGFR1, FGFR2, FGFR3, FGFR4) kin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/9/2020
Entry Details
US Patent

TargetFibroblast growth factor receptor 1(Human)
Principia Biopharma

US Patent
LigandChemical structure of BindingDB Monomer ID 430233BDBM430233(2-(3-(2-(6-(2,6-dichloro-3,5-dimethoxyphenyl)-2-(m...)
Affinity DataIC50: 4.80nMAssay Description:A Caliper-based kinase assay (Caliper Life Sciences, Hopkinton, Mass.) was used to measure inhibition of FGFR family (FGFR1, FGFR2, FGFR3, FGFR4) kin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/9/2020
Entry Details
US Patent

TargetFibroblast growth factor receptor 1(Human)
Principia Biopharma

US Patent
LigandChemical structure of BindingDB Monomer ID 430254BDBM430254(N-(4-(2-(6-(2-chloro-3,5-dimethoxyphenyl)-2-(methy...)
Affinity DataIC50: 4.90nMAssay Description:A Caliper-based kinase assay (Caliper Life Sciences, Hopkinton, Mass.) was used to measure inhibition of FGFR family (FGFR1, FGFR2, FGFR3, FGFR4) kin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/9/2020
Entry Details
US Patent

TargetFibroblast growth factor receptor 1(Human)
Principia Biopharma

US Patent
LigandChemical structure of BindingDB Monomer ID 430246BDBM430246(N-(3-(2-(6-(2-chloro-3,5-dimethoxyphenyl)-2-(methy...)
Affinity DataIC50: 4.90nMAssay Description:A Caliper-based kinase assay (Caliper Life Sciences, Hopkinton, Mass.) was used to measure inhibition of FGFR family (FGFR1, FGFR2, FGFR3, FGFR4) kin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/9/2020
Entry Details
US Patent

TargetFibroblast growth factor receptor 1(Human)
Principia Biopharma

US Patent
LigandChemical structure of BindingDB Monomer ID 430229BDBM430229(2-(4-(3-(6-(2-chloro-3,5-dimethoxyphenyl)-2-(methy...)
Affinity DataIC50: 5nMAssay Description:A Caliper-based kinase assay (Caliper Life Sciences, Hopkinton, Mass.) was used to measure inhibition of FGFR family (FGFR1, FGFR2, FGFR3, FGFR4) kin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/9/2020
Entry Details
US Patent

TargetFibroblast growth factor receptor 1(Human)
Principia Biopharma

US Patent
LigandChemical structure of BindingDB Monomer ID 430250BDBM430250(2-cyano-N-(3-(2-(6-(2,6-dichloro-3,5-dimethoxyphen...)
Affinity DataIC50: 6.10nMAssay Description:A Caliper-based kinase assay (Caliper Life Sciences, Hopkinton, Mass.) was used to measure inhibition of FGFR family (FGFR1, FGFR2, FGFR3, FGFR4) kin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/9/2020
Entry Details
US Patent

TargetFibroblast growth factor receptor 1(Human)
Principia Biopharma

US Patent
LigandChemical structure of BindingDB Monomer ID 430249BDBM430249(N-(3-(2-(2-amino-6-(2-chloro-3,5-dimethoxyphenyl)-...)
Affinity DataIC50: 7.10nMAssay Description:A Caliper-based kinase assay (Caliper Life Sciences, Hopkinton, Mass.) was used to measure inhibition of FGFR family (FGFR1, FGFR2, FGFR3, FGFR4) kin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/9/2020
Entry Details
US Patent

TargetFibroblast growth factor receptor 1(Human)
Principia Biopharma

US Patent
LigandChemical structure of BindingDB Monomer ID 430234BDBM430234(2-(4-(2-(6-(2,6-dichloro-3,5-dimethoxyphenyl)-2-(m...)
Affinity DataIC50: 7.60nMAssay Description:A Caliper-based kinase assay (Caliper Life Sciences, Hopkinton, Mass.) was used to measure inhibition of FGFR family (FGFR1, FGFR2, FGFR3, FGFR4) kin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/9/2020
Entry Details
US Patent

TargetFibroblast growth factor receptor 1(Human)
Principia Biopharma

US Patent
LigandChemical structure of BindingDB Monomer ID 430267BDBM430267(N-(4-(2-(6-(2-chloro-3,5-dimethoxyphenyl)-2-((2-mo...)
Affinity DataIC50: 8.20nMAssay Description:A Caliper-based kinase assay (Caliper Life Sciences, Hopkinton, Mass.) was used to measure inhibition of FGFR family (FGFR1, FGFR2, FGFR3, FGFR4) kin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/9/2020
Entry Details
US Patent

TargetFibroblast growth factor receptor 1(Human)
Principia Biopharma

US Patent
LigandChemical structure of BindingDB Monomer ID 430256BDBM430256(4-amino-2-cyano-N-(3-(2-(6-(3,5-dimethoxyphenyl)-2...)
Affinity DataIC50: 8.60nMAssay Description:A Caliper-based kinase assay (Caliper Life Sciences, Hopkinton, Mass.) was used to measure inhibition of FGFR family (FGFR1, FGFR2, FGFR3, FGFR4) kin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/9/2020
Entry Details
US Patent

TargetFibroblast growth factor receptor 1(Human)
Principia Biopharma

US Patent
LigandChemical structure of BindingDB Monomer ID 430261BDBM430261(N-(5-(2-(6-(2-chloro-3,5-dimethoxyphenyl)-2-(methy...)
Affinity DataIC50: 9.30nMAssay Description:A Caliper-based kinase assay (Caliper Life Sciences, Hopkinton, Mass.) was used to measure inhibition of FGFR family (FGFR1, FGFR2, FGFR3, FGFR4) kin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/9/2020
Entry Details
US Patent

TargetFibroblast growth factor receptor 1(Human)
Principia Biopharma

US Patent
LigandChemical structure of BindingDB Monomer ID 430243BDBM430243(N-(3-(2-(6-(2-chloro-3,5-dimethoxyphenyl)-2-(methy...)
Affinity DataIC50: 10nMAssay Description:A Caliper-based kinase assay (Caliper Life Sciences, Hopkinton, Mass.) was used to measure inhibition of FGFR family (FGFR1, FGFR2, FGFR3, FGFR4) kin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/9/2020
Entry Details
US Patent

TargetFibroblast growth factor receptor 1(Human)
Principia Biopharma

US Patent
LigandChemical structure of BindingDB Monomer ID 430239BDBM430239(N-(6-(2-(6-(2-chloro-3,5-dimethoxyphenyl)-2-(methy...)
Affinity DataIC50: 13.8nMAssay Description:A Caliper-based kinase assay (Caliper Life Sciences, Hopkinton, Mass.) was used to measure inhibition of FGFR family (FGFR1, FGFR2, FGFR3, FGFR4) kin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/9/2020
Entry Details
US Patent

TargetFibroblast growth factor receptor 1(Human)
Principia Biopharma

US Patent
LigandChemical structure of BindingDB Monomer ID 430266BDBM430266(N-(4-(2-(6-(2-chloro-3,5-dimethoxyphenyl)-2-((2-mo...)
Affinity DataIC50: 14.6nMAssay Description:A Caliper-based kinase assay (Caliper Life Sciences, Hopkinton, Mass.) was used to measure inhibition of FGFR family (FGFR1, FGFR2, FGFR3, FGFR4) kin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/9/2020
Entry Details
US Patent

TargetFibroblast growth factor receptor 1(Human)
Principia Biopharma

US Patent
LigandChemical structure of BindingDB Monomer ID 430252BDBM430252(N-(3-(2-(6-(2-chloro-3,5-dimethoxyphenyl)-2-((2-hy...)
Affinity DataIC50: 20.7nMAssay Description:A Caliper-based kinase assay (Caliper Life Sciences, Hopkinton, Mass.) was used to measure inhibition of FGFR family (FGFR1, FGFR2, FGFR3, FGFR4) kin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/9/2020
Entry Details
US Patent

TargetFibroblast growth factor receptor 1(Human)
Principia Biopharma

US Patent
LigandChemical structure of BindingDB Monomer ID 430231BDBM430231(2-(4-(2-(6-(2-chloro-3,5-dimethoxyphenyl)-2-(methy...)
Affinity DataIC50: 22.6nMAssay Description:A Caliper-based kinase assay (Caliper Life Sciences, Hopkinton, Mass.) was used to measure inhibition of FGFR family (FGFR1, FGFR2, FGFR3, FGFR4) kin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/9/2020
Entry Details
US Patent

TargetFibroblast growth factor receptor 1(Human)
Principia Biopharma

US Patent
LigandChemical structure of BindingDB Monomer ID 430236BDBM430236(N-(1-(2-(6-(2-chloro-3,5-dimethoxyphenyl)-2-(methy...)
Affinity DataIC50: 34.2nMAssay Description:A Caliper-based kinase assay (Caliper Life Sciences, Hopkinton, Mass.) was used to measure inhibition of FGFR family (FGFR1, FGFR2, FGFR3, FGFR4) kin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/9/2020
Entry Details
US Patent

TargetFibroblast growth factor receptor 1(Human)
Principia Biopharma

US Patent
LigandChemical structure of BindingDB Monomer ID 430232BDBM430232(2-((3aR,6aS)-5-(2-(6-(2-chloro-3,5-dimethoxyphenyl...)
Affinity DataIC50: 46.5nMAssay Description:A Caliper-based kinase assay (Caliper Life Sciences, Hopkinton, Mass.) was used to measure inhibition of FGFR family (FGFR1, FGFR2, FGFR3, FGFR4) kin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/9/2020
Entry Details
US Patent

TargetFibroblast growth factor receptor 1(Human)
Principia Biopharma

US Patent
LigandChemical structure of BindingDB Monomer ID 430264BDBM430264(N-(tert-butyl)-3-(4-(3-(6-(2-chloro-3,5-dimethoxyp...)
Affinity DataIC50: 47nMAssay Description:A Caliper-based kinase assay (Caliper Life Sciences, Hopkinton, Mass.) was used to measure inhibition of FGFR family (FGFR1, FGFR2, FGFR3, FGFR4) kin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/9/2020
Entry Details
US Patent

TargetFibroblast growth factor receptor 1(Human)
Principia Biopharma

US Patent
LigandChemical structure of BindingDB Monomer ID 430253BDBM430253(2-cyano-N-(3-(2-(6-(3,5-dimethoxyphenyl)-2-(methyl...)
Affinity DataIC50: 122nMAssay Description:A Caliper-based kinase assay (Caliper Life Sciences, Hopkinton, Mass.) was used to measure inhibition of FGFR family (FGFR1, FGFR2, FGFR3, FGFR4) kin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/9/2020
Entry Details
US Patent

TargetFibroblast growth factor receptor 1(Human)
Principia Biopharma

US Patent
LigandChemical structure of BindingDB Monomer ID 430241BDBM430241(N-(3-(2-(6-(2-chlorophenyl)-2-((4-(diethylamino)bu...)
Affinity DataIC50: 126nMAssay Description:A Caliper-based kinase assay (Caliper Life Sciences, Hopkinton, Mass.) was used to measure inhibition of FGFR family (FGFR1, FGFR2, FGFR3, FGFR4) kin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/9/2020
Entry Details
US Patent

TargetFibroblast growth factor receptor 1(Human)
Principia Biopharma

US Patent
LigandChemical structure of BindingDB Monomer ID 430260BDBM430260(2-cyano-N-(3-(2-(6-(2-fluoro-3-methoxyphenyl)-2-(m...)
Affinity DataIC50: 146nMAssay Description:A Caliper-based kinase assay (Caliper Life Sciences, Hopkinton, Mass.) was used to measure inhibition of FGFR family (FGFR1, FGFR2, FGFR3, FGFR4) kin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/9/2020
Entry Details
US Patent

TargetFibroblast growth factor receptor 1(Human)
Principia Biopharma

US Patent
LigandChemical structure of BindingDB Monomer ID 430263BDBM430263(N-(4-(2-(6-(2-chloro-3,5-dimethoxyphenyl)-2-(methy...)
Affinity DataIC50: 258nMAssay Description:A Caliper-based kinase assay (Caliper Life Sciences, Hopkinton, Mass.) was used to measure inhibition of FGFR family (FGFR1, FGFR2, FGFR3, FGFR4) kin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/9/2020
Entry Details
US Patent

TargetFibroblast growth factor receptor 1(Human)
Principia Biopharma

US Patent
LigandChemical structure of BindingDB Monomer ID 430228BDBM430228(US10538517, Compound Table 2.2 | 2-(3-(2-(6-(2-chl...)
Affinity DataIC50: 331nMAssay Description:A Caliper-based kinase assay (Caliper Life Sciences, Hopkinton, Mass.) was used to measure inhibition of FGFR family (FGFR1, FGFR2, FGFR3, FGFR4) kin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/9/2020
Entry Details
US Patent

TargetFibroblast growth factor receptor 1(Human)
Principia Biopharma

US Patent
LigandChemical structure of BindingDB Monomer ID 430228BDBM430228(US10538517, Compound Table 2.2 | 2-(3-(2-(6-(2-chl...)
Affinity DataIC50: 331nMAssay Description:A Caliper-based kinase assay (Caliper Life Sciences, Hopkinton, Mass.) was used to measure inhibition of FGFR family (FGFR1, FGFR2, FGFR3, FGFR4) kin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/9/2020
Entry Details
US Patent

TargetFibroblast growth factor receptor 1(Human)
Principia Biopharma

US Patent
LigandChemical structure of BindingDB Monomer ID 430258BDBM430258(2-cyano-N-(3-(2-(6-(2,4-dichlorophenyl)-2-(methyla...)
Affinity DataIC50: 1.29E+3nMAssay Description:A Caliper-based kinase assay (Caliper Life Sciences, Hopkinton, Mass.) was used to measure inhibition of FGFR family (FGFR1, FGFR2, FGFR3, FGFR4) kin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/9/2020
Entry Details
US Patent

TargetFibroblast growth factor receptor 1(Human)
Principia Biopharma

US Patent
LigandChemical structure of BindingDB Monomer ID 430259BDBM430259(2-cyano-N-(3-(2-(6-(2,5-dimethylphenyl)-2-(methyla...)
Affinity DataIC50: 5.00E+3nMAssay Description:A Caliper-based kinase assay (Caliper Life Sciences, Hopkinton, Mass.) was used to measure inhibition of FGFR family (FGFR1, FGFR2, FGFR3, FGFR4) kin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/9/2020
Entry Details
US Patent