Compile Data Set for Download or QSAR
Report error Found 38 Enz. Inhib. hit(s) with all data for entry = 8895
TargetTryptophan 2,3-dioxygenase(Human)
Pfizer

US Patent
LigandChemical structure of BindingDB Monomer ID 426672BDBM426672(US10544095, Example 120)
Affinity DataIC50: 120nMAssay Description:To measure the TDO2 activity, the procedure described in Dolusic et al. J. Med. Chem.; 2011, 54, 5320-533 was adapted: the reaction mixture contained...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/1/2020
Entry Details
US Patent

TargetTryptophan 2,3-dioxygenase(Human)
Pfizer

US Patent
LigandChemical structure of BindingDB Monomer ID 426656BDBM426656(US10544095, Example 79)
Affinity DataIC50: 120nMAssay Description:To measure the TDO2 activity, the procedure described in Dolusic et al. J. Med. Chem.; 2011, 54, 5320-533 was adapted: the reaction mixture contained...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/1/2020
Entry Details
US Patent

TargetTryptophan 2,3-dioxygenase(Human)
Pfizer

US Patent
LigandChemical structure of BindingDB Monomer ID 426655BDBM426655(US10544095, Example 77)
Affinity DataIC50: 170nMAssay Description:To measure the TDO2 activity, the procedure described in Dolusic et al. J. Med. Chem.; 2011, 54, 5320-533 was adapted: the reaction mixture contained...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/1/2020
Entry Details
US Patent

TargetTryptophan 2,3-dioxygenase(Human)
Pfizer

US Patent
LigandChemical structure of BindingDB Monomer ID 426649BDBM426649(US10544095, Example 35)
Affinity DataIC50: 420nMAssay Description:To measure the TDO2 activity, the procedure described in Dolusic et al. J. Med. Chem.; 2011, 54, 5320-533 was adapted: the reaction mixture contained...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/1/2020
Entry Details
US Patent

TargetTryptophan 2,3-dioxygenase(Human)
Pfizer

US Patent
LigandChemical structure of BindingDB Monomer ID 426654BDBM426654(US10544095, Example 76)
Affinity DataIC50: 470nMAssay Description:To measure the TDO2 activity, the procedure described in Dolusic et al. J. Med. Chem.; 2011, 54, 5320-533 was adapted: the reaction mixture contained...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/1/2020
Entry Details
US Patent

TargetTryptophan 2,3-dioxygenase(Human)
Pfizer

US Patent
LigandChemical structure of BindingDB Monomer ID 426648BDBM426648(US10544095, Example 34)
Affinity DataIC50: 520nMAssay Description:To measure the TDO2 activity, the procedure described in Dolusic et al. J. Med. Chem.; 2011, 54, 5320-533 was adapted: the reaction mixture contained...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/1/2020
Entry Details
US Patent

TargetTryptophan 2,3-dioxygenase(Human)
Pfizer

US Patent
LigandChemical structure of BindingDB Monomer ID 426653BDBM426653(US10544095, Example 58)
Affinity DataIC50: 530nMAssay Description:To measure the TDO2 activity, the procedure described in Dolusic et al. J. Med. Chem.; 2011, 54, 5320-533 was adapted: the reaction mixture contained...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/1/2020
Entry Details
US Patent

TargetTryptophan 2,3-dioxygenase(Human)
Pfizer

US Patent
LigandChemical structure of BindingDB Monomer ID 426663BDBM426663(US10544095, Example 93)
Affinity DataIC50: 550nMAssay Description:To measure the TDO2 activity, the procedure described in Dolusic et al. J. Med. Chem.; 2011, 54, 5320-533 was adapted: the reaction mixture contained...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/1/2020
Entry Details
US Patent

TargetTryptophan 2,3-dioxygenase(Human)
Pfizer

US Patent
LigandChemical structure of BindingDB Monomer ID 426647BDBM426647(US10544095, Example 32)
Affinity DataIC50: 730nMAssay Description:To measure the TDO2 activity, the procedure described in Dolusic et al. J. Med. Chem.; 2011, 54, 5320-533 was adapted: the reaction mixture contained...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/1/2020
Entry Details
US Patent

TargetTryptophan 2,3-dioxygenase(Human)
Pfizer

US Patent
LigandChemical structure of BindingDB Monomer ID 426646BDBM426646(US10544095, Example 26)
Affinity DataIC50: 730nMAssay Description:To measure the TDO2 activity, the procedure described in Dolusic et al. J. Med. Chem.; 2011, 54, 5320-533 was adapted: the reaction mixture contained...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/1/2020
Entry Details
US Patent

TargetTryptophan 2,3-dioxygenase(Human)
Pfizer

US Patent
LigandChemical structure of BindingDB Monomer ID 426645BDBM426645(US10544095, Example 21)
Affinity DataIC50: 740nMAssay Description:To measure the TDO2 activity, the procedure described in Dolusic et al. J. Med. Chem.; 2011, 54, 5320-533 was adapted: the reaction mixture contained...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/1/2020
Entry Details
US Patent

TargetTryptophan 2,3-dioxygenase(Human)
Pfizer

US Patent
LigandChemical structure of BindingDB Monomer ID 426650BDBM426650(US10544095, Example 36)
Affinity DataIC50: 770nMAssay Description:To measure the TDO2 activity, the procedure described in Dolusic et al. J. Med. Chem.; 2011, 54, 5320-533 was adapted: the reaction mixture contained...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/1/2020
Entry Details
US Patent

TargetTryptophan 2,3-dioxygenase(Human)
Pfizer

US Patent
LigandChemical structure of BindingDB Monomer ID 426668BDBM426668(US10544095, Example 97)
Affinity DataIC50: 820nMAssay Description:To measure the TDO2 activity, the procedure described in Dolusic et al. J. Med. Chem.; 2011, 54, 5320-533 was adapted: the reaction mixture contained...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/1/2020
Entry Details
US Patent

TargetTryptophan 2,3-dioxygenase(Human)
Pfizer

US Patent
LigandChemical structure of BindingDB Monomer ID 426664BDBM426664(US10544095, Example 94)
Affinity DataIC50: 840nMAssay Description:To measure the TDO2 activity, the procedure described in Dolusic et al. J. Med. Chem.; 2011, 54, 5320-533 was adapted: the reaction mixture contained...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/1/2020
Entry Details
US Patent

TargetTryptophan 2,3-dioxygenase(Human)
Pfizer

US Patent
LigandChemical structure of BindingDB Monomer ID 426671BDBM426671(US10544095, Example 101)
Affinity DataIC50: 840nMAssay Description:To measure the TDO2 activity, the procedure described in Dolusic et al. J. Med. Chem.; 2011, 54, 5320-533 was adapted: the reaction mixture contained...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/1/2020
Entry Details
US Patent

TargetTryptophan 2,3-dioxygenase(Human)
Pfizer

US Patent
LigandChemical structure of BindingDB Monomer ID 426641BDBM426641(US10544095, Example 8)
Affinity DataIC50: 890nMAssay Description:To measure the TDO2 activity, the procedure described in Dolusic et al. J. Med. Chem.; 2011, 54, 5320-533 was adapted: the reaction mixture contained...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/1/2020
Entry Details
US Patent

TargetTryptophan 2,3-dioxygenase(Human)
Pfizer

US Patent
LigandChemical structure of BindingDB Monomer ID 426657BDBM426657(US10544095, Example 80)
Affinity DataIC50: 900nMAssay Description:To measure the TDO2 activity, the procedure described in Dolusic et al. J. Med. Chem.; 2011, 54, 5320-533 was adapted: the reaction mixture contained...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/1/2020
Entry Details
US Patent

TargetTryptophan 2,3-dioxygenase(Human)
Pfizer

US Patent
LigandChemical structure of BindingDB Monomer ID 426669BDBM426669(US10544095, Example 98)
Affinity DataIC50: 910nMAssay Description:To measure the TDO2 activity, the procedure described in Dolusic et al. J. Med. Chem.; 2011, 54, 5320-533 was adapted: the reaction mixture contained...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/1/2020
Entry Details
US Patent

TargetTryptophan 2,3-dioxygenase(Human)
Pfizer

US Patent
LigandChemical structure of BindingDB Monomer ID 426651BDBM426651(US10544095, Example 40)
Affinity DataIC50: 930nMAssay Description:To measure the TDO2 activity, the procedure described in Dolusic et al. J. Med. Chem.; 2011, 54, 5320-533 was adapted: the reaction mixture contained...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/1/2020
Entry Details
US Patent

TargetTryptophan 2,3-dioxygenase(Human)
Pfizer

US Patent
LigandChemical structure of BindingDB Monomer ID 426660BDBM426660(US10544095, Example 87)
Affinity DataIC50: 930nMAssay Description:To measure the TDO2 activity, the procedure described in Dolusic et al. J. Med. Chem.; 2011, 54, 5320-533 was adapted: the reaction mixture contained...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/1/2020
Entry Details
US Patent

TargetTryptophan 2,3-dioxygenase(Human)
Pfizer

US Patent
LigandChemical structure of BindingDB Monomer ID 426661BDBM426661(US10544095, Example 88)
Affinity DataIC50: 940nMAssay Description:To measure the TDO2 activity, the procedure described in Dolusic et al. J. Med. Chem.; 2011, 54, 5320-533 was adapted: the reaction mixture contained...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/1/2020
Entry Details
US Patent

TargetTryptophan 2,3-dioxygenase(Human)
Pfizer

US Patent
LigandChemical structure of BindingDB Monomer ID 426652BDBM426652(US10544095, Example 50)
Affinity DataIC50: 960nMAssay Description:To measure the TDO2 activity, the procedure described in Dolusic et al. J. Med. Chem.; 2011, 54, 5320-533 was adapted: the reaction mixture contained...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/1/2020
Entry Details
US Patent

TargetTryptophan 2,3-dioxygenase(Human)
Pfizer

US Patent
LigandChemical structure of BindingDB Monomer ID 426667BDBM426667(US10544095, Example 96)
Affinity DataIC50: 1.00E+3nMAssay Description:To measure the TDO2 activity, the procedure described in Dolusic et al. J. Med. Chem.; 2011, 54, 5320-533 was adapted: the reaction mixture contained...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/1/2020
Entry Details
US Patent

TargetTryptophan 2,3-dioxygenase(Human)
Pfizer

US Patent
LigandChemical structure of BindingDB Monomer ID 426639BDBM426639(US10544095, Example 6)
Affinity DataIC50: 1.00E+3nMAssay Description:To measure the TDO2 activity, the procedure described in Dolusic et al. J. Med. Chem.; 2011, 54, 5320-533 was adapted: the reaction mixture contained...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/1/2020
Entry Details
US Patent

TargetTryptophan 2,3-dioxygenase(Human)
Pfizer

US Patent
LigandChemical structure of BindingDB Monomer ID 426633BDBM426633(US10544095, Example 2)
Affinity DataIC50: 1.10E+3nMAssay Description:To measure the TDO2 activity, the procedure described in Dolusic et al. J. Med. Chem.; 2011, 54, 5320-533 was adapted: the reaction mixture contained...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/1/2020
Entry Details
US Patent

TargetTryptophan 2,3-dioxygenase(Human)
Pfizer

US Patent
LigandChemical structure of BindingDB Monomer ID 426670BDBM426670(US10544095, Example 99)
Affinity DataIC50: 1.10E+3nMAssay Description:To measure the TDO2 activity, the procedure described in Dolusic et al. J. Med. Chem.; 2011, 54, 5320-533 was adapted: the reaction mixture contained...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/1/2020
Entry Details
US Patent

TargetTryptophan 2,3-dioxygenase(Human)
Pfizer

US Patent
LigandChemical structure of BindingDB Monomer ID 426644BDBM426644(US10544095, Example 18)
Affinity DataIC50: 1.10E+3nMAssay Description:To measure the TDO2 activity, the procedure described in Dolusic et al. J. Med. Chem.; 2011, 54, 5320-533 was adapted: the reaction mixture contained...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/1/2020
Entry Details
US Patent

TargetTryptophan 2,3-dioxygenase(Human)
Pfizer

US Patent
LigandChemical structure of BindingDB Monomer ID 426665BDBM426665(US10544095, Example 95)
Affinity DataIC50: 1.30E+3nMAssay Description:To measure the TDO2 activity, the procedure described in Dolusic et al. J. Med. Chem.; 2011, 54, 5320-533 was adapted: the reaction mixture contained...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/1/2020
Entry Details
US Patent

TargetTryptophan 2,3-dioxygenase(Human)
Pfizer

US Patent
LigandChemical structure of BindingDB Monomer ID 426659BDBM426659(US10544095, Example 86)
Affinity DataIC50: 1.30E+3nMAssay Description:To measure the TDO2 activity, the procedure described in Dolusic et al. J. Med. Chem.; 2011, 54, 5320-533 was adapted: the reaction mixture contained...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/1/2020
Entry Details
US Patent

TargetTryptophan 2,3-dioxygenase(Human)
Pfizer

US Patent
LigandChemical structure of BindingDB Monomer ID 426632BDBM426632(US10544095, Example 1)
Affinity DataIC50: 1.50E+3nMAssay Description:To measure the TDO2 activity, the procedure described in Dolusic et al. J. Med. Chem.; 2011, 54, 5320-533 was adapted: the reaction mixture contained...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/1/2020
Entry Details
US Patent

TargetTryptophan 2,3-dioxygenase(Human)
Pfizer

US Patent
LigandChemical structure of BindingDB Monomer ID 426642BDBM426642(US10544095, Example 9)
Affinity DataIC50: 1.80E+3nMAssay Description:To measure the TDO2 activity, the procedure described in Dolusic et al. J. Med. Chem.; 2011, 54, 5320-533 was adapted: the reaction mixture contained...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/1/2020
Entry Details
US Patent

TargetTryptophan 2,3-dioxygenase(Human)
Pfizer

US Patent
LigandChemical structure of BindingDB Monomer ID 426658BDBM426658(US10544095, Example 84)
Affinity DataIC50: 1.90E+3nMAssay Description:To measure the TDO2 activity, the procedure described in Dolusic et al. J. Med. Chem.; 2011, 54, 5320-533 was adapted: the reaction mixture contained...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/1/2020
Entry Details
US Patent

TargetTryptophan 2,3-dioxygenase(Human)
Pfizer

US Patent
LigandChemical structure of BindingDB Monomer ID 426662BDBM426662(US10544095, Example 90)
Affinity DataIC50: 2.00E+3nMAssay Description:To measure the TDO2 activity, the procedure described in Dolusic et al. J. Med. Chem.; 2011, 54, 5320-533 was adapted: the reaction mixture contained...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/1/2020
Entry Details
US Patent

TargetTryptophan 2,3-dioxygenase(Human)
Pfizer

US Patent
LigandChemical structure of BindingDB Monomer ID 426637BDBM426637(US10544095, Example 4)
Affinity DataIC50: 2.10E+3nMAssay Description:To measure the TDO2 activity, the procedure described in Dolusic et al. J. Med. Chem.; 2011, 54, 5320-533 was adapted: the reaction mixture contained...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/1/2020
Entry Details
US Patent

TargetTryptophan 2,3-dioxygenase(Human)
Pfizer

US Patent
LigandChemical structure of BindingDB Monomer ID 426636BDBM426636(US10544095, Example 3)
Affinity DataIC50: 2.10E+3nMAssay Description:To measure the TDO2 activity, the procedure described in Dolusic et al. J. Med. Chem.; 2011, 54, 5320-533 was adapted: the reaction mixture contained...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/1/2020
Entry Details
US Patent

TargetTryptophan 2,3-dioxygenase(Human)
Pfizer

US Patent
LigandChemical structure of BindingDB Monomer ID 426643BDBM426643(US10544095, Example 10)
Affinity DataIC50: 2.40E+3nMAssay Description:To measure the TDO2 activity, the procedure described in Dolusic et al. J. Med. Chem.; 2011, 54, 5320-533 was adapted: the reaction mixture contained...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/1/2020
Entry Details
US Patent

TargetTryptophan 2,3-dioxygenase(Human)
Pfizer

US Patent
LigandChemical structure of BindingDB Monomer ID 426640BDBM426640(US10544095, Example 7)
Affinity DataIC50: 4.40E+3nMAssay Description:To measure the TDO2 activity, the procedure described in Dolusic et al. J. Med. Chem.; 2011, 54, 5320-533 was adapted: the reaction mixture contained...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/1/2020
Entry Details
US Patent

TargetTryptophan 2,3-dioxygenase(Human)
Pfizer

US Patent
LigandChemical structure of BindingDB Monomer ID 426638BDBM426638(US10544095, Example 5)
Affinity DataIC50: 4.70E+3nMAssay Description:To measure the TDO2 activity, the procedure described in Dolusic et al. J. Med. Chem.; 2011, 54, 5320-533 was adapted: the reaction mixture contained...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/1/2020
Entry Details
US Patent