Compile Data Set for Download or QSAR
Report error Found 4 Enz. Inhib. hit(s) with all data for entry = 9045
TargetTyrosine-protein kinase JAK2(Human)
Centaurus Biopharma

US Patent
LigandPNGBDBM433323(US10561657, Ruxolitinib | US10617692, Ruxolitinib ...)
Affinity DataIC50: 10nMAssay Description:A testing platform for kinase activity of JAK2 was established based on Homogeneous Time-Resolved Fluorescence (HTRF) assay, and the activities of th...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2020
Entry Details
US Patent

TargetTyrosine-protein kinase JAK2(Human)
Centaurus Biopharma

US Patent
LigandPNGBDBM437666(US10617692, Compound III)
Affinity DataIC50: 10nMAssay Description:A testing platform for kinase activity of JAK2 was established based on Homogeneous Time-Resolved Fluorescence (HTRF) assay, and the activities of th...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2020
Entry Details
US Patent

TargetTyrosine-protein kinase JAK2(Human)
Centaurus Biopharma

US Patent
LigandPNGBDBM437665(US10617692, Compound II)
Affinity DataIC50: 10nMAssay Description:A testing platform for kinase activity of JAK2 was established based on Homogeneous Time-Resolved Fluorescence (HTRF) assay, and the activities of th...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2020
Entry Details
US Patent

TargetTyrosine-protein kinase JAK2(Human)
Centaurus Biopharma

US Patent
LigandPNGBDBM437667(US10617692, Compound IV)
Affinity DataIC50: 30nMAssay Description:A testing platform for kinase activity of JAK2 was established based on Homogeneous Time-Resolved Fluorescence (HTRF) assay, and the activities of th...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2020
Entry Details
US Patent