Compile Data Set for Download or QSAR
Report error Found 43 Enz. Inhib. hit(s) with all data for entry = 9046
TargetTyrosyl-DNA phosphodiesterase 2(Human)
Regents of The University of Minnesota

US Patent
LigandChemical structure of BindingDB Monomer ID 437709BDBM437709(US10617706, Example 143)
Affinity DataIC50: 3.85nMAssay Description:The enzymatic activity of TDP2 was measured with a SUMO hTDP2cat fluorescence-based biochemical assay. To a black 384-well plate, 10 μL of compo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2020
Entry Details
US Patent

TargetTyrosyl-DNA phosphodiesterase 2(Human)
Regents of The University of Minnesota

US Patent
LigandChemical structure of BindingDB Monomer ID 437686BDBM437686(US10617706, Example 120)
Affinity DataIC50: 5.01nMAssay Description:The enzymatic activity of TDP2 was measured with a SUMO hTDP2cat fluorescence-based biochemical assay. To a black 384-well plate, 10 μL of compo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2020
Entry Details
US Patent

TargetTyrosyl-DNA phosphodiesterase 2(Human)
Regents of The University of Minnesota

US Patent
LigandChemical structure of BindingDB Monomer ID 437707BDBM437707(US10617706, Example 141)
Affinity DataIC50: 6.09nMAssay Description:The enzymatic activity of TDP2 was measured with a SUMO hTDP2cat fluorescence-based biochemical assay. To a black 384-well plate, 10 μL of compo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2020
Entry Details
US Patent

TargetTyrosyl-DNA phosphodiesterase 2(Human)
Regents of The University of Minnesota

US Patent
LigandChemical structure of BindingDB Monomer ID 437708BDBM437708(US10617706, Example 142)
Affinity DataIC50: 6.49nMAssay Description:The enzymatic activity of TDP2 was measured with a SUMO hTDP2cat fluorescence-based biochemical assay. To a black 384-well plate, 10 μL of compo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2020
Entry Details
US Patent

TargetTyrosyl-DNA phosphodiesterase 2(Human)
Regents of The University of Minnesota

US Patent
LigandChemical structure of BindingDB Monomer ID 437703BDBM437703(US10617706, Example 137)
Affinity DataIC50: 7.25nMAssay Description:The enzymatic activity of TDP2 was measured with a SUMO hTDP2cat fluorescence-based biochemical assay. To a black 384-well plate, 10 μL of compo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2020
Entry Details
US Patent

TargetTyrosyl-DNA phosphodiesterase 2(Human)
Regents of The University of Minnesota

US Patent
LigandChemical structure of BindingDB Monomer ID 437685BDBM437685(US10617706, Example 119)
Affinity DataIC50: 8.28nMAssay Description:The enzymatic activity of TDP2 was measured with a SUMO hTDP2cat fluorescence-based biochemical assay. To a black 384-well plate, 10 μL of compo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2020
Entry Details
US Patent

TargetTyrosyl-DNA phosphodiesterase 2(Human)
Regents of The University of Minnesota

US Patent
LigandChemical structure of BindingDB Monomer ID 437705BDBM437705(US10617706, Example 139)
Affinity DataIC50: 13.6nMAssay Description:The enzymatic activity of TDP2 was measured with a SUMO hTDP2cat fluorescence-based biochemical assay. To a black 384-well plate, 10 μL of compo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2020
Entry Details
US Patent

TargetTyrosyl-DNA phosphodiesterase 2(Human)
Regents of The University of Minnesota

US Patent
LigandChemical structure of BindingDB Monomer ID 437704BDBM437704(US10617706, Example 138)
Affinity DataIC50: 19.8nMAssay Description:The enzymatic activity of TDP2 was measured with a SUMO hTDP2cat fluorescence-based biochemical assay. To a black 384-well plate, 10 μL of compo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2020
Entry Details
US Patent

TargetTyrosyl-DNA phosphodiesterase 2(Human)
Regents of The University of Minnesota

US Patent
LigandChemical structure of BindingDB Monomer ID 437694BDBM437694(US10617706, Example 128)
Affinity DataIC50: 32.8nMAssay Description:The enzymatic activity of TDP2 was measured with a SUMO hTDP2cat fluorescence-based biochemical assay. To a black 384-well plate, 10 μL of compo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2020
Entry Details
US Patent

TargetTyrosyl-DNA phosphodiesterase 2(Human)
Regents of The University of Minnesota

US Patent
LigandChemical structure of BindingDB Monomer ID 437692BDBM437692(US10617706, Example 126)
Affinity DataIC50: 33.1nMAssay Description:The enzymatic activity of TDP2 was measured with a SUMO hTDP2cat fluorescence-based biochemical assay. To a black 384-well plate, 10 μL of compo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2020
Entry Details
US Patent

TargetTyrosyl-DNA phosphodiesterase 2(Human)
Regents of The University of Minnesota

US Patent
LigandChemical structure of BindingDB Monomer ID 437697BDBM437697(US10617706, Example 131)
Affinity DataIC50: 35nMAssay Description:The enzymatic activity of TDP2 was measured with a SUMO hTDP2cat fluorescence-based biochemical assay. To a black 384-well plate, 10 μL of compo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2020
Entry Details
US Patent

TargetTyrosyl-DNA phosphodiesterase 2(Human)
Regents of The University of Minnesota

US Patent
LigandChemical structure of BindingDB Monomer ID 437696BDBM437696(US10617706, Example 130)
Affinity DataIC50: 38nMAssay Description:The enzymatic activity of TDP2 was measured with a SUMO hTDP2cat fluorescence-based biochemical assay. To a black 384-well plate, 10 μL of compo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2020
Entry Details
US Patent

TargetTyrosyl-DNA phosphodiesterase 2(Human)
Regents of The University of Minnesota

US Patent
LigandChemical structure of BindingDB Monomer ID 437689BDBM437689(US10617706, Example 123)
Affinity DataIC50: 39nMAssay Description:The enzymatic activity of TDP2 was measured with a SUMO hTDP2cat fluorescence-based biochemical assay. To a black 384-well plate, 10 μL of compo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2020
Entry Details
US Patent

TargetTyrosyl-DNA phosphodiesterase 2(Human)
Regents of The University of Minnesota

US Patent
LigandChemical structure of BindingDB Monomer ID 437687BDBM437687(US10617706, Example 121)
Affinity DataIC50: 47nMAssay Description:The enzymatic activity of TDP2 was measured with a SUMO hTDP2cat fluorescence-based biochemical assay. To a black 384-well plate, 10 μL of compo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2020
Entry Details
US Patent

TargetTyrosyl-DNA phosphodiesterase 2(Human)
Regents of The University of Minnesota

US Patent
LigandChemical structure of BindingDB Monomer ID 437699BDBM437699(US10617706, Example 133)
Affinity DataIC50: 59nMAssay Description:The enzymatic activity of TDP2 was measured with a SUMO hTDP2cat fluorescence-based biochemical assay. To a black 384-well plate, 10 μL of compo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2020
Entry Details
US Patent

TargetTyrosyl-DNA phosphodiesterase 2(Human)
Regents of The University of Minnesota

US Patent
LigandChemical structure of BindingDB Monomer ID 437695BDBM437695(US10617706, Example 129)
Affinity DataIC50: 64.7nMAssay Description:The enzymatic activity of TDP2 was measured with a SUMO hTDP2cat fluorescence-based biochemical assay. To a black 384-well plate, 10 μL of compo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2020
Entry Details
US Patent

TargetTyrosyl-DNA phosphodiesterase 2(Human)
Regents of The University of Minnesota

US Patent
LigandChemical structure of BindingDB Monomer ID 437693BDBM437693(US10617706, Example 127)
Affinity DataIC50: 70.4nMAssay Description:The enzymatic activity of TDP2 was measured with a SUMO hTDP2cat fluorescence-based biochemical assay. To a black 384-well plate, 10 μL of compo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2020
Entry Details
US Patent

TargetTyrosyl-DNA phosphodiesterase 2(Human)
Regents of The University of Minnesota

US Patent
LigandChemical structure of BindingDB Monomer ID 437702BDBM437702(US10617706, Example 136)
Affinity DataIC50: 119nMAssay Description:The enzymatic activity of TDP2 was measured with a SUMO hTDP2cat fluorescence-based biochemical assay. To a black 384-well plate, 10 μL of compo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2020
Entry Details
US Patent

TargetTyrosyl-DNA phosphodiesterase 2(Human)
Regents of The University of Minnesota

US Patent
LigandChemical structure of BindingDB Monomer ID 437698BDBM437698(US10617706, Example 132)
Affinity DataIC50: 119nMAssay Description:The enzymatic activity of TDP2 was measured with a SUMO hTDP2cat fluorescence-based biochemical assay. To a black 384-well plate, 10 μL of compo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2020
Entry Details
US Patent

TargetTyrosyl-DNA phosphodiesterase 2(Human)
Regents of The University of Minnesota

US Patent
LigandChemical structure of BindingDB Monomer ID 437683BDBM437683(US10617706, Example 117)
Affinity DataIC50: 131nMAssay Description:The enzymatic activity of TDP2 was measured with a SUMO hTDP2cat fluorescence-based biochemical assay. To a black 384-well plate, 10 μL of compo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2020
Entry Details
US Patent

TargetTyrosyl-DNA phosphodiesterase 2(Human)
Regents of The University of Minnesota

US Patent
LigandChemical structure of BindingDB Monomer ID 437682BDBM437682(US10617706, Example 116)
Affinity DataIC50: 153nMAssay Description:The enzymatic activity of TDP2 was measured with a SUMO hTDP2cat fluorescence-based biochemical assay. To a black 384-well plate, 10 μL of compo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2020
Entry Details
US Patent

TargetTyrosyl-DNA phosphodiesterase 2(Human)
Regents of The University of Minnesota

US Patent
LigandChemical structure of BindingDB Monomer ID 437701BDBM437701(US10617706, Example 135)
Affinity DataIC50: 185nMAssay Description:The enzymatic activity of TDP2 was measured with a SUMO hTDP2cat fluorescence-based biochemical assay. To a black 384-well plate, 10 μL of compo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2020
Entry Details
US Patent

TargetTyrosyl-DNA phosphodiesterase 2(Human)
Regents of The University of Minnesota

US Patent
LigandChemical structure of BindingDB Monomer ID 437675BDBM437675(US10617706, Example 110 | US10617706, Example 109)
Affinity DataIC50: 186nMAssay Description:The enzymatic activity of TDP2 was measured with a SUMO hTDP2cat fluorescence-based biochemical assay. To a black 384-well plate, 10 μL of compo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2020
Entry Details
US Patent

TargetTyrosyl-DNA phosphodiesterase 2(Human)
Regents of The University of Minnesota

US Patent
LigandChemical structure of BindingDB Monomer ID 437677BDBM437677(US10617706, Example 111)
Affinity DataIC50: 196nMAssay Description:The enzymatic activity of TDP2 was measured with a SUMO hTDP2cat fluorescence-based biochemical assay. To a black 384-well plate, 10 μL of compo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2020
Entry Details
US Patent

TargetTyrosyl-DNA phosphodiesterase 2(Human)
Regents of The University of Minnesota

US Patent
LigandChemical structure of BindingDB Monomer ID 437690BDBM437690(US10617706, Example 124)
Affinity DataIC50: 239nMAssay Description:The enzymatic activity of TDP2 was measured with a SUMO hTDP2cat fluorescence-based biochemical assay. To a black 384-well plate, 10 μL of compo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2020
Entry Details
US Patent

TargetTyrosyl-DNA phosphodiesterase 2(Human)
Regents of The University of Minnesota

US Patent
LigandChemical structure of BindingDB Monomer ID 437706BDBM437706(US10617706, Example 140)
Affinity DataIC50: 274nMAssay Description:The enzymatic activity of TDP2 was measured with a SUMO hTDP2cat fluorescence-based biochemical assay. To a black 384-well plate, 10 μL of compo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2020
Entry Details
US Patent

TargetTyrosyl-DNA phosphodiesterase 2(Human)
Regents of The University of Minnesota

US Patent
LigandChemical structure of BindingDB Monomer ID 437700BDBM437700(US10617706, Example 134)
Affinity DataIC50: 277nMAssay Description:The enzymatic activity of TDP2 was measured with a SUMO hTDP2cat fluorescence-based biochemical assay. To a black 384-well plate, 10 μL of compo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2020
Entry Details
US Patent

TargetTyrosyl-DNA phosphodiesterase 2(Human)
Regents of The University of Minnesota

US Patent
LigandChemical structure of BindingDB Monomer ID 437672BDBM437672(US10617706, Example 106)
Affinity DataIC50: 301nMAssay Description:The enzymatic activity of TDP2 was measured with a SUMO hTDP2cat fluorescence-based biochemical assay. To a black 384-well plate, 10 μL of compo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2020
Entry Details
US Patent

TargetTyrosyl-DNA phosphodiesterase 2(Human)
Regents of The University of Minnesota

US Patent
LigandChemical structure of BindingDB Monomer ID 437691BDBM437691(US10617706, Example 125)
Affinity DataIC50: 317nMAssay Description:The enzymatic activity of TDP2 was measured with a SUMO hTDP2cat fluorescence-based biochemical assay. To a black 384-well plate, 10 μL of compo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2020
Entry Details
US Patent

TargetTyrosyl-DNA phosphodiesterase 2(Human)
Regents of The University of Minnesota

US Patent
LigandChemical structure of BindingDB Monomer ID 437688BDBM437688(US10617706, Example 122)
Affinity DataIC50: 359nMAssay Description:The enzymatic activity of TDP2 was measured with a SUMO hTDP2cat fluorescence-based biochemical assay. To a black 384-well plate, 10 μL of compo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2020
Entry Details
US Patent

TargetTyrosyl-DNA phosphodiesterase 2(Human)
Regents of The University of Minnesota

US Patent
LigandChemical structure of BindingDB Monomer ID 437678BDBM437678(US10617706, Example 112)
Affinity DataIC50: 383nMAssay Description:The enzymatic activity of TDP2 was measured with a SUMO hTDP2cat fluorescence-based biochemical assay. To a black 384-well plate, 10 μL of compo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2020
Entry Details
US Patent

TargetTyrosyl-DNA phosphodiesterase 2(Human)
Regents of The University of Minnesota

US Patent
LigandChemical structure of BindingDB Monomer ID 437684BDBM437684(US10617706, Example 118)
Affinity DataIC50: 795nMAssay Description:The enzymatic activity of TDP2 was measured with a SUMO hTDP2cat fluorescence-based biochemical assay. To a black 384-well plate, 10 μL of compo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2020
Entry Details
US Patent

TargetTyrosyl-DNA phosphodiesterase 2(Human)
Regents of The University of Minnesota

US Patent
LigandChemical structure of BindingDB Monomer ID 437668BDBM437668(US10617706, Example 102)
Affinity DataIC50: 880nMAssay Description:The enzymatic activity of TDP2 was measured with a SUMO hTDP2cat fluorescence-based biochemical assay. To a black 384-well plate, 10 μL of compo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2020
Entry Details
US Patent

TargetTyrosyl-DNA phosphodiesterase 2(Human)
Regents of The University of Minnesota

US Patent
LigandChemical structure of BindingDB Monomer ID 437675BDBM437675(US10617706, Example 110 | US10617706, Example 109)
Affinity DataIC50: 934nMAssay Description:The enzymatic activity of TDP2 was measured with a SUMO hTDP2cat fluorescence-based biochemical assay. To a black 384-well plate, 10 μL of compo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2020
Entry Details
US Patent

TargetTyrosyl-DNA phosphodiesterase 2(Human)
Regents of The University of Minnesota

US Patent
LigandChemical structure of BindingDB Monomer ID 437669BDBM437669(US10617706, Example 103)
Affinity DataIC50: 964nMAssay Description:The enzymatic activity of TDP2 was measured with a SUMO hTDP2cat fluorescence-based biochemical assay. To a black 384-well plate, 10 μL of compo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2020
Entry Details
US Patent

TargetTyrosyl-DNA phosphodiesterase 2(Human)
Regents of The University of Minnesota

US Patent
LigandChemical structure of BindingDB Monomer ID 437681BDBM437681(US10617706, Example 115)
Affinity DataIC50: 993nMAssay Description:The enzymatic activity of TDP2 was measured with a SUMO hTDP2cat fluorescence-based biochemical assay. To a black 384-well plate, 10 μL of compo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2020
Entry Details
US Patent

TargetTyrosyl-DNA phosphodiesterase 2(Human)
Regents of The University of Minnesota

US Patent
LigandChemical structure of BindingDB Monomer ID 437664BDBM437664(US10617706, Example 101)
Affinity DataIC50: 1.03E+3nMAssay Description:The enzymatic activity of TDP2 was measured with a SUMO hTDP2cat fluorescence-based biochemical assay. To a black 384-well plate, 10 μL of compo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2020
Entry Details
US Patent

TargetTyrosyl-DNA phosphodiesterase 2(Human)
Regents of The University of Minnesota

US Patent
LigandChemical structure of BindingDB Monomer ID 437671BDBM437671(US10617706, Example 105)
Affinity DataIC50: 1.13E+3nMAssay Description:The enzymatic activity of TDP2 was measured with a SUMO hTDP2cat fluorescence-based biochemical assay. To a black 384-well plate, 10 μL of compo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2020
Entry Details
US Patent

TargetTyrosyl-DNA phosphodiesterase 2(Human)
Regents of The University of Minnesota

US Patent
LigandChemical structure of BindingDB Monomer ID 437680BDBM437680(US10617706, Example 114)
Affinity DataIC50: 1.31E+3nMAssay Description:The enzymatic activity of TDP2 was measured with a SUMO hTDP2cat fluorescence-based biochemical assay. To a black 384-well plate, 10 μL of compo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2020
Entry Details
US Patent

TargetTyrosyl-DNA phosphodiesterase 2(Human)
Regents of The University of Minnesota

US Patent
LigandChemical structure of BindingDB Monomer ID 437670BDBM437670(US10617706, Example 104)
Affinity DataIC50: 1.53E+3nMAssay Description:The enzymatic activity of TDP2 was measured with a SUMO hTDP2cat fluorescence-based biochemical assay. To a black 384-well plate, 10 μL of compo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2020
Entry Details
US Patent

TargetTyrosyl-DNA phosphodiesterase 2(Human)
Regents of The University of Minnesota

US Patent
LigandChemical structure of BindingDB Monomer ID 437679BDBM437679(US10617706, Example 113)
Affinity DataIC50: 1.60E+3nMAssay Description:The enzymatic activity of TDP2 was measured with a SUMO hTDP2cat fluorescence-based biochemical assay. To a black 384-well plate, 10 μL of compo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2020
Entry Details
US Patent

TargetTyrosyl-DNA phosphodiesterase 2(Human)
Regents of The University of Minnesota

US Patent
LigandChemical structure of BindingDB Monomer ID 437673BDBM437673(US10617706, Example 107)
Affinity DataIC50: 3.80E+3nMAssay Description:The enzymatic activity of TDP2 was measured with a SUMO hTDP2cat fluorescence-based biochemical assay. To a black 384-well plate, 10 μL of compo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2020
Entry Details
US Patent

TargetTyrosyl-DNA phosphodiesterase 2(Human)
Regents of The University of Minnesota

US Patent
LigandChemical structure of BindingDB Monomer ID 437674BDBM437674(US10617706, Example 108)
Affinity DataIC50: 1.00E+4nMAssay Description:The enzymatic activity of TDP2 was measured with a SUMO hTDP2cat fluorescence-based biochemical assay. To a black 384-well plate, 10 μL of compo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2020
Entry Details
US Patent