Compile Data Set for Download or QSAR
Report error Found 19 Enz. Inhib. hit(s) with all data for entry = 11386
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Human)
Columbia University

US Patent
LigandChemical structure of BindingDB Monomer ID 50241831BDBM50241831(CHEMBL4062273 | US10899756, Compound U | US1062611...)
Affinity DataIC50: 0.0440nMAssay Description:Materials and Methods: PDE5 inhibition was assayed at BPS Bioscience (San Diego, Calif.) using BPS PDE assay kits (BPS Catalog number 60300, enzyme l...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/8/2023
Entry Details
US Patent

TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Human)
Columbia University

US Patent
LigandChemical structure of BindingDB Monomer ID 50241831BDBM50241831(CHEMBL4062273 | US10899756, Compound U | US1062611...)
Affinity DataIC50: 0.0560nMAssay Description:Materials and Methods: PDE5 inhibition was assayed at BPS Bioscience (San Diego, Calif.) using BPS PDE assay kits (BPS Catalog number 60300, enzyme l...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/8/2023
Entry Details
US Patent

TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Human)
Columbia University

US Patent
LigandChemical structure of BindingDB Monomer ID 480487BDBM480487(US10899756, Compound D | US10626113, Compound D)
Affinity DataIC50: 0.0700nMAssay Description:Materials and Methods: PDE5 inhibition was assayed at BPS Bioscience (San Diego, Calif.) using BPS PDE assay kits (BPS Catalog number 60300, enzyme l...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/8/2023
Entry Details
US Patent

TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Human)
Columbia University

US Patent
LigandChemical structure of BindingDB Monomer ID 50241832BDBM50241832(CHEMBL4083986 | US10899756, Compound C | US1062611...)
Affinity DataIC50: 0.200nMAssay Description:Materials and Methods: PDE5 inhibition was assayed at BPS Bioscience (San Diego, Calif.) using BPS PDE assay kits (BPS Catalog number 60300, enzyme l...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/8/2023
Entry Details
US Patent

TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Human)
Columbia University

US Patent
LigandChemical structure of BindingDB Monomer ID 50242157BDBM50242157(CHEMBL4070894 | US10899756, Compound B | US1062611...)
Affinity DataIC50: 1nMAssay Description:Materials and Methods: PDE5 inhibition was assayed at BPS Bioscience (San Diego, Calif.) using BPS PDE assay kits (BPS Catalog number 60300, enzyme l...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/8/2023
Entry Details
US Patent

TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Human)
Columbia University

US Patent
LigandChemical structure of BindingDB Monomer ID 50241834BDBM50241834(CHEMBL4065036 | US10899756, Compound R | US1062611...)
Affinity DataIC50: 1.5nMAssay Description:Materials and Methods: PDE5 inhibition was assayed at BPS Bioscience (San Diego, Calif.) using BPS PDE assay kits (BPS Catalog number 60300, enzyme l...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/8/2023
Entry Details
US Patent

TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Human)
Columbia University

US Patent
LigandChemical structure of BindingDB Monomer ID 50241837BDBM50241837(CHEMBL4102913 | US10899756, Compound G | US1062611...)
Affinity DataIC50: 1.55nMAssay Description:Materials and Methods: PDE5 inhibition was assayed at BPS Bioscience (San Diego, Calif.) using BPS PDE assay kits (BPS Catalog number 60300, enzyme l...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/8/2023
Entry Details
US Patent

TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Human)
Columbia University

US Patent
LigandChemical structure of BindingDB Monomer ID 480489BDBM480489(US10899756, Compound F | US10626113, Compound F)
Affinity DataIC50: 5.40nMAssay Description:Materials and Methods: PDE5 inhibition was assayed at BPS Bioscience (San Diego, Calif.) using BPS PDE assay kits (BPS Catalog number 60300, enzyme l...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/8/2023
Entry Details
US Patent

TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Human)
Columbia University

US Patent
LigandChemical structure of BindingDB Monomer ID 480504BDBM480504(US10899756, Compound W | US10626113, Compound O)
Affinity DataIC50: 10.6nMAssay Description:Materials and Methods: PDE5 inhibition was assayed at BPS Bioscience (San Diego, Calif.) using BPS PDE assay kits (BPS Catalog number 60300, enzyme l...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/8/2023
Entry Details
US Patent

TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Human)
Columbia University

US Patent
LigandChemical structure of BindingDB Monomer ID 50242154BDBM50242154(CHEMBL4099788 | US10899756, Compound A | US1062611...)
Affinity DataIC50: 21.6nMAssay Description:Materials and Methods: PDE5 inhibition was assayed at BPS Bioscience (San Diego, Calif.) using BPS PDE assay kits (BPS Catalog number 60300, enzyme l...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/8/2023
Entry Details
US Patent

TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Human)
Columbia University

US Patent
LigandChemical structure of BindingDB Monomer ID 480503BDBM480503(US10899756, Compound V | US10626113, Compound N)
Affinity DataIC50: 26.9nMAssay Description:Materials and Methods: PDE5 inhibition was assayed at BPS Bioscience (San Diego, Calif.) using BPS PDE assay kits (BPS Catalog number 60300, enzyme l...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/8/2023
Entry Details
US Patent

TargetRod cGMP-specific 3',5'-cyclic phosphodiesterase subunit alpha(Human)
Columbia University

US Patent
LigandChemical structure of BindingDB Monomer ID 480487BDBM480487(US10899756, Compound D | US10626113, Compound D)
Affinity DataIC50: 30nMAssay Description:Materials and Methods: PDE5 inhibition was assayed at BPS Bioscience (San Diego, Calif.) using BPS PDE assay kits (BPS Catalog number 60300, enzyme l...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/8/2023
Entry Details
US Patent

TargetRod cGMP-specific 3',5'-cyclic phosphodiesterase subunit alpha(Human)
Columbia University

US Patent
LigandChemical structure of BindingDB Monomer ID 50241831BDBM50241831(CHEMBL4062273 | US10899756, Compound U | US1062611...)
Affinity DataIC50: 30.1nMAssay Description:Materials and Methods: PDE5 inhibition was assayed at BPS Bioscience (San Diego, Calif.) using BPS PDE assay kits (BPS Catalog number 60300, enzyme l...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/8/2023
Entry Details
US Patent

TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Human)
Columbia University

US Patent
LigandChemical structure of BindingDB Monomer ID 480488BDBM480488(US10899756, Compound E | US10626113, Compound E)
Affinity DataIC50: 43.8nMAssay Description:Materials and Methods: PDE5 inhibition was assayed at BPS Bioscience (San Diego, Calif.) using BPS PDE assay kits (BPS Catalog number 60300, enzyme l...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/8/2023
Entry Details
US Patent

TargetRod cGMP-specific 3',5'-cyclic phosphodiesterase subunit alpha(Human)
Columbia University

US Patent
LigandChemical structure of BindingDB Monomer ID 50241837BDBM50241837(CHEMBL4102913 | US10899756, Compound G | US1062611...)
Affinity DataIC50: 100nMAssay Description:Materials and Methods: PDE5 inhibition was assayed at BPS Bioscience (San Diego, Calif.) using BPS PDE assay kits (BPS Catalog number 60300, enzyme l...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/8/2023
Entry Details
US Patent

TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Human)
Columbia University

US Patent
LigandChemical structure of BindingDB Monomer ID 50241833BDBM50241833(CHEMBL4073617 | US10899756, Compound Q | US1062611...)
Affinity DataIC50: 337nMAssay Description:Materials and Methods: PDE5 inhibition was assayed at BPS Bioscience (San Diego, Calif.) using BPS PDE assay kits (BPS Catalog number 60300, enzyme l...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/8/2023
Entry Details
US Patent

TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Human)
Columbia University

US Patent
LigandChemical structure of BindingDB Monomer ID 480501BDBM480501(US10899756, Compound T | US10626113, Compound L)
Affinity DataIC50: 425nMAssay Description:Materials and Methods: PDE5 inhibition was assayed at BPS Bioscience (San Diego, Calif.) using BPS PDE assay kits (BPS Catalog number 60300, enzyme l...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/8/2023
Entry Details
US Patent

TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Human)
Columbia University

US Patent
LigandChemical structure of BindingDB Monomer ID 480500BDBM480500(US10899756, Compound S | US10626113, Compound K)
Affinity DataIC50: 593nMAssay Description:Materials and Methods: PDE5 inhibition was assayed at BPS Bioscience (San Diego, Calif.) using BPS PDE assay kits (BPS Catalog number 60300, enzyme l...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/8/2023
Entry Details
US Patent

TargetRod cGMP-specific 3',5'-cyclic phosphodiesterase subunit alpha(Human)
Columbia University

US Patent
LigandChemical structure of BindingDB Monomer ID 480488BDBM480488(US10899756, Compound E | US10626113, Compound E)
Affinity DataIC50: 6.62E+3nMAssay Description:Materials and Methods: PDE5 inhibition was assayed at BPS Bioscience (San Diego, Calif.) using BPS PDE assay kits (BPS Catalog number 60300, enzyme l...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/8/2023
Entry Details
US Patent