Compile Data Set for Download or QSAR
Report error Found 70 Enz. Inhib. hit(s) with all data for entry = 9200
TargetSRSF protein kinase 1(Human)
Exonate

US Patent
LigandChemical structure of BindingDB Monomer ID 448544BDBM448544(US10696661, Compound 5 | N-(2-(4-(furan-2-ylmethyl...)
Affinity DataIC50: 0.370nMAssay Description:Screening of a series of molecules identified compounds (Compounds 5, 8, 16 to 18 and 43 of Table 3) that had improved potency against SRPK1 against ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2021
Entry Details
US Patent

TargetSRSF protein kinase 1(Human)
Exonate

US Patent
LigandChemical structure of BindingDB Monomer ID 448727BDBM448727(5-(tetrahydro-2H-pyran-4-yl)-N-(2-(4-(thiazol-5- y...)
Affinity DataIC50: 0.5nMAssay Description:Screening of a series of molecules identified compounds (Compounds 5, 8, 16 to 18 and 43 of Table 3) that had improved potency against SRPK1 against ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2021
Entry Details
US Patent

TargetSRSF protein kinase 1(Human)
Exonate

US Patent
LigandChemical structure of BindingDB Monomer ID 448683BDBM448683(N-(2-(4-(thiazol-5-ylmethyl)piperazin-1-yl)-5- (tr...)
Affinity DataIC50: 0.5nMAssay Description:Screening of a series of molecules identified compounds (Compounds 5, 8, 16 to 18 and 43 of Table 3) that had improved potency against SRPK1 against ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2021
Entry Details
US Patent

TargetSRSF protein kinase 1(Human)
Exonate

US Patent
LigandChemical structure of BindingDB Monomer ID 448695BDBM448695(N-(2-(4-(furan-3-ylmethyl)piperazin-1-yl)-5- (trif...)
Affinity DataIC50: 0.700nMAssay Description:Screening of a series of molecules identified compounds (Compounds 5, 8, 16 to 18 and 43 of Table 3) that had improved potency against SRPK1 against ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2021
Entry Details
US Patent

TargetSRSF protein kinase 1(Human)
Exonate

US Patent
LigandChemical structure of BindingDB Monomer ID 448663BDBM448663(N-(2-(4-(oxazol-5-ylmethyl)piperazin-1-yl)-5- (tri...)
Affinity DataIC50: 0.760nMAssay Description:Screening of a series of molecules identified compounds (Compounds 5, 8, 16 to 18 and 43 of Table 3) that had improved potency against SRPK1 against ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2021
Entry Details
US Patent

TargetSRSF protein kinase 1(Human)
Exonate

US Patent
LigandChemical structure of BindingDB Monomer ID 448673BDBM448673(N-(5-chloro-2-(4-(furan-2-ylmethyl)piperazin-1-yl)...)
Affinity DataIC50: 1.20nMAssay Description:Screening of a series of molecules identified compounds (Compounds 5, 8, 16 to 18 and 43 of Table 3) that had improved potency against SRPK1 against ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2021
Entry Details
US Patent

TargetSRSF protein kinase 1(Human)
Exonate

US Patent
LigandChemical structure of BindingDB Monomer ID 448662BDBM448662(N-(2-(4-(oxazol-4-ylmethyl)piperazin-1-yl)-5- (tri...)
Affinity DataIC50: 1.30nMAssay Description:Screening of a series of molecules identified compounds (Compounds 5, 8, 16 to 18 and 43 of Table 3) that had improved potency against SRPK1 against ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2021
Entry Details
US Patent

TargetSRSF protein kinase 1(Human)
Exonate

US Patent
LigandChemical structure of BindingDB Monomer ID 448675BDBM448675(N-(2-(4-(furan-2-ylmethyl)piperazin-1-yl)-5- (trif...)
Affinity DataIC50: 1.40nMAssay Description:Screening of a series of molecules identified compounds (Compounds 5, 8, 16 to 18 and 43 of Table 3) that had improved potency against SRPK1 against ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2021
Entry Details
US Patent

TargetSRSF protein kinase 1(Human)
Exonate

US Patent
LigandChemical structure of BindingDB Monomer ID 448664BDBM448664(5-(tetrahydro-2H-pyran-4-yl)-N-(2-(4-(thiazol-4- y...)
Affinity DataIC50: 1.70nMAssay Description:Screening of a series of molecules identified compounds (Compounds 5, 8, 16 to 18 and 43 of Table 3) that had improved potency against SRPK1 against ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2021
Entry Details
US Patent

TargetSRSF protein kinase 1(Human)
Exonate

US Patent
LigandChemical structure of BindingDB Monomer ID 448726BDBM448726(N-(2-(4-(isoxazol-5-ylmethyl)piperazin-1-yl)-5-(tr...)
Affinity DataIC50: 1.80nMAssay Description:Screening of a series of molecules identified compounds (Compounds 5, 8, 16 to 18 and 43 of Table 3) that had improved potency against SRPK1 against ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2021
Entry Details
US Patent

TargetSRSF protein kinase 1(Human)
Exonate

US Patent
LigandChemical structure of BindingDB Monomer ID 448697BDBM448697(N-(2-(4-(furan-3-ylmethyl)piperazin-1-yl)-5- (trif...)
Affinity DataIC50: 1.80nMAssay Description:Screening of a series of molecules identified compounds (Compounds 5, 8, 16 to 18 and 43 of Table 3) that had improved potency against SRPK1 against ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2021
Entry Details
US Patent

TargetSRSF protein kinase 1(Human)
Exonate

US Patent
LigandChemical structure of BindingDB Monomer ID 448715BDBM448715(N-(2-(4-(isoxazol-5-ylmethyl)piperazin-1-yl)-5-(tr...)
Affinity DataIC50: 2.80nMAssay Description:Screening of a series of molecules identified compounds (Compounds 5, 8, 16 to 18 and 43 of Table 3) that had improved potency against SRPK1 against ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2021
Entry Details
US Patent

TargetSRSF protein kinase 1(Human)
Exonate

US Patent
LigandChemical structure of BindingDB Monomer ID 448647BDBM448647(N-(2-(4-((1H-pyrazol-3-yl)methyl)piperazin-1-yl)-5...)
Affinity DataIC50: 3.5nMAssay Description:Screening of a series of molecules identified compounds (Compounds 5, 8, 16 to 18 and 43 of Table 3) that had improved potency against SRPK1 against ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2021
Entry Details
US Patent

TargetSRSF protein kinase 1(Human)
Exonate

US Patent
LigandChemical structure of BindingDB Monomer ID 448696BDBM448696(N-(2-(4-((5-methylfuran-2-yl)methyl)piperazin-1-yl...)
Affinity DataIC50: 3.70nMAssay Description:Screening of a series of molecules identified compounds (Compounds 5, 8, 16 to 18 and 43 of Table 3) that had improved potency against SRPK1 against ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2021
Entry Details
US Patent

TargetSRSF protein kinase 1(Human)
Exonate

US Patent
LigandChemical structure of BindingDB Monomer ID 448661BDBM448661(N-(2-(4-(oxazol-2-ylmethyl)piperazin-1-yl)-5- (tri...)
Affinity DataIC50: 4.60nMAssay Description:Screening of a series of molecules identified compounds (Compounds 5, 8, 16 to 18 and 43 of Table 3) that had improved potency against SRPK1 against ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2021
Entry Details
US Patent

TargetSRSF protein kinase 1(Human)
Exonate

US Patent
LigandChemical structure of BindingDB Monomer ID 448729BDBM448729(N-(2-(4-(furan-3-ylmethyl)piperazin-1-yl)-5- (trif...)
Affinity DataIC50: 5.30nMAssay Description:Screening of a series of molecules identified compounds (Compounds 5, 8, 16 to 18 and 43 of Table 3) that had improved potency against SRPK1 against ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2021
Entry Details
US Patent

TargetSRSF protein kinase 1(Human)
Exonate

US Patent
LigandChemical structure of BindingDB Monomer ID 448717BDBM448717(N-(2-(4-(isoxazol-5-ylmethyl)piperazin-1-yl)-5-(tr...)
Affinity DataIC50: 5.5nMAssay Description:Screening of a series of molecules identified compounds (Compounds 5, 8, 16 to 18 and 43 of Table 3) that had improved potency against SRPK1 against ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2021
Entry Details
US Patent

TargetSRSF protein kinase 1(Human)
Exonate

US Patent
LigandChemical structure of BindingDB Monomer ID 448682BDBM448682(N-(2-(4-(thiazol-4-ylmethyl)piperazin-1-yl)-5- (tr...)
Affinity DataIC50: 6.70nMAssay Description:Screening of a series of molecules identified compounds (Compounds 5, 8, 16 to 18 and 43 of Table 3) that had improved potency against SRPK1 against ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2021
Entry Details
US Patent

TargetSRSF protein kinase 1(Human)
Exonate

US Patent
LigandChemical structure of BindingDB Monomer ID 448674BDBM448674(N-(5-chloro-2-(4-(oxazol-4-ylmethyl)piperazin-1-yl...)
Affinity DataIC50: 8.20nMAssay Description:Screening of a series of molecules identified compounds (Compounds 5, 8, 16 to 18 and 43 of Table 3) that had improved potency against SRPK1 against ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2021
Entry Details
US Patent

TargetSRSF protein kinase 1(Human)
Exonate

US Patent
LigandChemical structure of BindingDB Monomer ID 448723BDBM448723(N-(2-(4-(isoxazol-4-ylmethyl)piperazin-1-yl)-5-(tr...)
Affinity DataIC50: 8.80nMAssay Description:Screening of a series of molecules identified compounds (Compounds 5, 8, 16 to 18 and 43 of Table 3) that had improved potency against SRPK1 against ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2021
Entry Details
US Patent

TargetSRSF protein kinase 1(Human)
Exonate

US Patent
LigandChemical structure of BindingDB Monomer ID 448718BDBM448718(US10696661, Compound 65)
Affinity DataIC50: 9.70nMAssay Description:Screening of a series of molecules identified compounds (Compounds 5, 8, 16 to 18 and 43 of Table 3) that had improved potency against SRPK1 against ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2021
Entry Details
US Patent

TargetSRSF protein kinase 1(Human)
Exonate

US Patent
LigandChemical structure of BindingDB Monomer ID 448698BDBM448698(5-methyl-N-(2-(4-((5-methylfuran-2-yl)methyl)piper...)
Affinity DataIC50: 10.7nMAssay Description:Screening of a series of molecules identified compounds (Compounds 5, 8, 16 to 18 and 43 of Table 3) that had improved potency against SRPK1 against ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2021
Entry Details
US Patent

TargetSRSF protein kinase 1(Human)
Exonate

US Patent
LigandChemical structure of BindingDB Monomer ID 448670BDBM448670(N-(2-(4-((1H-pyrazol-3-yl)methyl)piperazin-1-yl)-5...)
Affinity DataIC50: 10.9nMAssay Description:Screening of a series of molecules identified compounds (Compounds 5, 8, 16 to 18 and 43 of Table 3) that had improved potency against SRPK1 against ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2021
Entry Details
US Patent

TargetSRSF protein kinase 1(Human)
Exonate

US Patent
LigandChemical structure of BindingDB Monomer ID 448672BDBM448672(N-(2-(4-((1-methyl-1H-pyrazol-3-yl)methyl)piperazi...)
Affinity DataIC50: 11.3nMAssay Description:Screening of a series of molecules identified compounds (Compounds 5, 8, 16 to 18 and 43 of Table 3) that had improved potency against SRPK1 against ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2021
Entry Details
US Patent

TargetSRSF protein kinase 1(Human)
Exonate

US Patent
LigandChemical structure of BindingDB Monomer ID 448684BDBM448684(N-(2-(4-((1H-pyrazol-3-yl)methyl)piperazin-1-yl)-5...)
Affinity DataIC50: 12.7nMAssay Description:Screening of a series of molecules identified compounds (Compounds 5, 8, 16 to 18 and 43 of Table 3) that had improved potency against SRPK1 against ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2021
Entry Details
US Patent

TargetSRSF protein kinase 1(Human)
Exonate

US Patent
LigandChemical structure of BindingDB Monomer ID 448667BDBM448667(5-(pyridin-4-yl)-N-(2-(4-(thiazol-4-ylmethyl)piper...)
Affinity DataIC50: 13.7nMAssay Description:Screening of a series of molecules identified compounds (Compounds 5, 8, 16 to 18 and 43 of Table 3) that had improved potency against SRPK1 against ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2021
Entry Details
US Patent

TargetSRSF protein kinase 1(Human)
Exonate

US Patent
LigandChemical structure of BindingDB Monomer ID 448681BDBM448681(N-(2-(4-(thiazol-2-ylmethyl)piperazin-1-yl)-5- (tr...)
Affinity DataIC50: 14.1nMAssay Description:Screening of a series of molecules identified compounds (Compounds 5, 8, 16 to 18 and 43 of Table 3) that had improved potency against SRPK1 against ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2021
Entry Details
US Patent

TargetSRSF protein kinase 1(Human)
Exonate

US Patent
LigandChemical structure of BindingDB Monomer ID 448548BDBM448548(5-methyl-N-(2-(4-((furan-2-yl)methyl)piperazin-1-y...)
Affinity DataIC50: 17.6nMAssay Description:Screening of a series of molecules identified compounds (Compounds 5, 8, 16 to 18 and 43 of Table 3) that had improved potency against SRPK1 against ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2021
Entry Details
US Patent

TargetSRSF protein kinase 1(Human)
Exonate

US Patent
LigandChemical structure of BindingDB Monomer ID 448704BDBM448704(N-(2-(4-(oxazol-4-ylmethyl)piperazin-1-yl)-5-(trif...)
Affinity DataIC50: 21nMAssay Description:Screening of a series of molecules identified compounds (Compounds 5, 8, 16 to 18 and 43 of Table 3) that had improved potency against SRPK1 against ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2021
Entry Details
US Patent

TargetSRSF protein kinase 1(Human)
Exonate

US Patent
LigandChemical structure of BindingDB Monomer ID 448657BDBM448657(N-(2-(4-((5-methylfuran-2-yl)methyl)piperazin-1-yl...)
Affinity DataIC50: 21.4nMAssay Description:Screening of a series of molecules identified compounds (Compounds 5, 8, 16 to 18 and 43 of Table 3) that had improved potency against SRPK1 against ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2021
Entry Details
US Patent

TargetSRSF protein kinase 1(Human)
Exonate

US Patent
LigandChemical structure of BindingDB Monomer ID 448687BDBM448687(N-(2-(4-(oxazol-4-ylmethyl)piperazin-1-yl)-5- (tri...)
Affinity DataIC50: 21.6nMAssay Description:Screening of a series of molecules identified compounds (Compounds 5, 8, 16 to 18 and 43 of Table 3) that had improved potency against SRPK1 against ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2021
Entry Details
US Patent

TargetSRSF protein kinase 1(Human)
Exonate

US Patent
LigandChemical structure of BindingDB Monomer ID 448699BDBM448699(N-(2-(4-(furan-3-ylmethyl)piperazin-1-yl)-5- (trif...)
Affinity DataIC50: 21.9nMAssay Description:Screening of a series of molecules identified compounds (Compounds 5, 8, 16 to 18 and 43 of Table 3) that had improved potency against SRPK1 against ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2021
Entry Details
US Patent

TargetSRSF protein kinase 1(Human)
Exonate

US Patent
LigandChemical structure of BindingDB Monomer ID 448685BDBM448685(N-(2-(4-((1-methyl-1H-pyrazol-3-yl)methyl)piperazi...)
Affinity DataIC50: 27nMAssay Description:Screening of a series of molecules identified compounds (Compounds 5, 8, 16 to 18 and 43 of Table 3) that had improved potency against SRPK1 against ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2021
Entry Details
US Patent

TargetSRSF protein kinase 1(Human)
Exonate

US Patent
LigandChemical structure of BindingDB Monomer ID 448680BDBM448680(N-(5-chloro-2-(4-(furan-2-ylmethyl)piperazin-1- yl...)
Affinity DataIC50: 27.3nMAssay Description:Screening of a series of molecules identified compounds (Compounds 5, 8, 16 to 18 and 43 of Table 3) that had improved potency against SRPK1 against ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2021
Entry Details
US Patent

TargetSRSF protein kinase 1(Human)
Exonate

US Patent
LigandChemical structure of BindingDB Monomer ID 448668BDBM448668(5-(pyridin-4-yl)-N-(2-(5-(thiazol-2-ylmethyl)piper...)
Affinity DataIC50: 27.5nMAssay Description:Screening of a series of molecules identified compounds (Compounds 5, 8, 16 to 18 and 43 of Table 3) that had improved potency against SRPK1 against ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2021
Entry Details
US Patent

TargetSRSF protein kinase 1(Human)
Exonate

US Patent
LigandChemical structure of BindingDB Monomer ID 448693BDBM448693(US10696661, Compound 73 | N-(2-(4-(1H-imidazol-4-y...)
Affinity DataIC50: 28.7nMAssay Description:Screening of a series of molecules identified compounds (Compounds 5, 8, 16 to 18 and 43 of Table 3) that had improved potency against SRPK1 against ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2021
Entry Details
US Patent

TargetSRSF protein kinase 1(Human)
Exonate

US Patent
LigandChemical structure of BindingDB Monomer ID 448693BDBM448693(US10696661, Compound 73 | N-(2-(4-(1H-imidazol-4-y...)
Affinity DataIC50: 28.7nMAssay Description:Screening of a series of molecules identified compounds (Compounds 5, 8, 16 to 18 and 43 of Table 3) that had improved potency against SRPK1 against ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2021
Entry Details
US Patent

TargetSRSF protein kinase 1(Human)
Exonate

US Patent
LigandChemical structure of BindingDB Monomer ID 448690BDBM448690(N-(2-(4-((1H-indol-3-yl)methyl)piperazin-1-yl)-5- ...)
Affinity DataIC50: 31.3nMAssay Description:Screening of a series of molecules identified compounds (Compounds 5, 8, 16 to 18 and 43 of Table 3) that had improved potency against SRPK1 against ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2021
Entry Details
US Patent

TargetSRSF protein kinase 1(Human)
Exonate

US Patent
LigandChemical structure of BindingDB Monomer ID 448700BDBM448700(N-(2-(4-((5-methylfuran-2-yl)methyl)piperazin-1-yl...)
Affinity DataIC50: 32.6nMAssay Description:Screening of a series of molecules identified compounds (Compounds 5, 8, 16 to 18 and 43 of Table 3) that had improved potency against SRPK1 against ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2021
Entry Details
US Patent

TargetSRSF protein kinase 1(Human)
Exonate

US Patent
LigandChemical structure of BindingDB Monomer ID 448722BDBM448722(N-(2-(4-(isoxazol-4-ylmethyl)piperazin-1-yl)-5-(tr...)
Affinity DataIC50: 33.5nMAssay Description:Screening of a series of molecules identified compounds (Compounds 5, 8, 16 to 18 and 43 of Table 3) that had improved potency against SRPK1 against ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2021
Entry Details
US Patent

TargetSRSF protein kinase 1(Human)
Exonate

US Patent
LigandChemical structure of BindingDB Monomer ID 448725BDBM448725(N-(2-(4-(isoxazol-4-ylmethyl)piperazin-1-yl)-5- (t...)
Affinity DataIC50: 35.3nMAssay Description:Screening of a series of molecules identified compounds (Compounds 5, 8, 16 to 18 and 43 of Table 3) that had improved potency against SRPK1 against ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2021
Entry Details
US Patent

TargetSRSF protein kinase 1(Human)
Exonate

US Patent
LigandChemical structure of BindingDB Monomer ID 448621BDBM448621(N-(2-(4-(thiazol-5-ylmethyl)piperazin-1-yl)-5- (tr...)
Affinity DataIC50: 39.5nMAssay Description:Screening of a series of molecules identified compounds (Compounds 5, 8, 16 to 18 and 43 of Table 3) that had improved potency against SRPK1 against ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2021
Entry Details
US Patent

TargetSRSF protein kinase 1(Human)
Exonate

US Patent
LigandChemical structure of BindingDB Monomer ID 448691BDBM448691(US10696661, Compound 39)
Affinity DataIC50: 60.7nMAssay Description:Screening of a series of molecules identified compounds (Compounds 5, 8, 16 to 18 and 43 of Table 3) that had improved potency against SRPK1 against ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2021
Entry Details
US Patent

TargetSRSF protein kinase 1(Human)
Exonate

US Patent
LigandChemical structure of BindingDB Monomer ID 448574BDBM448574(N-(2-(4-((1H-pyrazol-3-yl)methyl)piperazin-1-yl)-5...)
Affinity DataIC50: 62.4nMAssay Description:Screening of a series of molecules identified compounds (Compounds 5, 8, 16 to 18 and 43 of Table 3) that had improved potency against SRPK1 against ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2021
Entry Details
US Patent

TargetSRSF protein kinase 1(Human)
Exonate

US Patent
LigandChemical structure of BindingDB Monomer ID 448733BDBM448733(N-(2-(4-((1H-indol-3-yl)methyl)piperazin-1-yl)-5- ...)
Affinity DataIC50: 74.9nMAssay Description:Screening of a series of molecules identified compounds (Compounds 5, 8, 16 to 18 and 43 of Table 3) that had improved potency against SRPK1 against ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2021
Entry Details
US Patent

TargetSRSF protein kinase 1(Human)
Exonate

US Patent
LigandChemical structure of BindingDB Monomer ID 448714BDBM448714(N-(2-(4-((1H-pyrazol-4-yl)methyl)piperazin-1-yl)-5...)
Affinity DataIC50: 75.9nMAssay Description:Screening of a series of molecules identified compounds (Compounds 5, 8, 16 to 18 and 43 of Table 3) that had improved potency against SRPK1 against ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2021
Entry Details
US Patent

TargetSRSF protein kinase 1(Human)
Exonate

US Patent
LigandChemical structure of BindingDB Monomer ID 448592BDBM448592(N-(2-(4-(thiazol-4-ylmethyl)piperazin-1-yl)-5- (tr...)
Affinity DataIC50: 79.8nMAssay Description:Screening of a series of molecules identified compounds (Compounds 5, 8, 16 to 18 and 43 of Table 3) that had improved potency against SRPK1 against ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2021
Entry Details
US Patent

TargetSRSF protein kinase 1(Human)
Exonate

US Patent
LigandChemical structure of BindingDB Monomer ID 448706BDBM448706(N-(2-(4-(oxazol-4-ylmethyl)piperazin-1-yl)-5-(trif...)
Affinity DataIC50: 83.1nMAssay Description:Screening of a series of molecules identified compounds (Compounds 5, 8, 16 to 18 and 43 of Table 3) that had improved potency against SRPK1 against ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2021
Entry Details
US Patent

TargetSRSF protein kinase 1(Human)
Exonate

US Patent
LigandChemical structure of BindingDB Monomer ID 448545BDBM448545(N-(2-(4-((5-methyl-1,3,4-oxadiazol-2-yl)methyl)pip...)
Affinity DataIC50: 88.3nMAssay Description:Screening of a series of molecules identified compounds (Compounds 5, 8, 16 to 18 and 43 of Table 3) that had improved potency against SRPK1 against ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2021
Entry Details
US Patent

TargetSRSF protein kinase 1(Human)
Exonate

US Patent
LigandChemical structure of BindingDB Monomer ID 448665BDBM448665(US10696661, Compound 20)
Affinity DataIC50: 104nMAssay Description:Screening of a series of molecules identified compounds (Compounds 5, 8, 16 to 18 and 43 of Table 3) that had improved potency against SRPK1 against ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2021
Entry Details
US Patent

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