Compile Data Set for Download or QSAR
Report error Found 455 Enz. Inhib. hit(s) with all data for entry = 9247
LigandChemical structure of BindingDB Monomer ID 452916BDBM452916(7-amino-5-methyl-3- [[3-[(1S,5S,6R)-3- phenyl-6-bi...)
Affinity DataIC50: 1.5nMAssay Description:The IC50 (effective concentration) of compounds on the human TRPA1 channel was determined using a FLIPR Tetra instrument. CHO cells expressing TRPA1 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/14/2021
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 452792BDBM452792(1-((3-((1S,5S,6R)-3- (3-fluorophenyl) bicyclo[3.1....)
Affinity DataIC50: 1.70nMAssay Description:The IC50 (effective concentration) of compounds on the human TRPA1 channel was determined using a FLIPR Tetra instrument. CHO cells expressing TRPA1 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/14/2021
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 452903BDBM452903(7-methyl-1-((3- ((1S,5S,6R)-3- phenylbicyclo[3.1.0...)
Affinity DataIC50: 1.70nMAssay Description:The IC50 (effective concentration) of compounds on the human TRPA1 channel was determined using a FLIPR Tetra instrument. CHO cells expressing TRPA1 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/14/2021
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 452862BDBM452862(1-((3-((1S,5S,6R)-3- (3-chlorophenyl) bicyclo[3.1....)
Affinity DataIC50: 1.80nMAssay Description:The IC50 (effective concentration) of compounds on the human TRPA1 channel was determined using a FLIPR Tetra instrument. CHO cells expressing TRPA1 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/14/2021
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 452929BDBM452929(US10711004, Example 251 | 7-methyl-1-[[3- [(1S,5S,...)
Affinity DataIC50: 2nMAssay Description:The IC50 (effective concentration) of compounds on the human TRPA1 channel was determined using a FLIPR Tetra instrument. CHO cells expressing TRPA1 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/14/2021
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 452929BDBM452929(US10711004, Example 251 | 7-methyl-1-[[3- [(1S,5S,...)
Affinity DataIC50: 2nMAssay Description:The IC50 (effective concentration) of compounds on the human TRPA1 channel was determined using a FLIPR Tetra instrument. CHO cells expressing TRPA1 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/14/2021
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 452932BDBM452932(US10711004, Example 254 | US10711004, Example 282 ...)
Affinity DataIC50: 2.10nMAssay Description:The IC50 (effective concentration) of compounds on the human TRPA1 channel was determined using a FLIPR Tetra instrument. CHO cells expressing TRPA1 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/14/2021
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 452915BDBM452915(1-((3-((1R,5S,6r)-3- (benzo[d]isothiazol- 5-yl)-3-...)
Affinity DataIC50: 2.10nMAssay Description:The IC50 (effective concentration) of compounds on the human TRPA1 channel was determined using a FLIPR Tetra instrument. CHO cells expressing TRPA1 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/14/2021
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 452793BDBM452793(1-((3-((1R,5R,6S)-3- (3-fluorophenyl) bicyclo[3.1....)
Affinity DataIC50: 2.30nMAssay Description:The IC50 (effective concentration) of compounds on the human TRPA1 channel was determined using a FLIPR Tetra instrument. CHO cells expressing TRPA1 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/14/2021
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 452948BDBM452948(7-methyl-1-[[3- [(1S,5S,6R)-3-(3,5- difluorophenyl...)
Affinity DataIC50: 2.40nMAssay Description:The IC50 (effective concentration) of compounds on the human TRPA1 channel was determined using a FLIPR Tetra instrument. CHO cells expressing TRPA1 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/14/2021
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 452778BDBM452778(1-((3-((1R,5S,6r)-3- (2,3-difluorophenyl)- 3-azabi...)
Affinity DataIC50: 2.5nMAssay Description:The IC50 (effective concentration) of compounds on the human TRPA1 channel was determined using a FLIPR Tetra instrument. CHO cells expressing TRPA1 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/14/2021
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 452892BDBM452892(6-((3-((1R,5S,6r)-3- (3-chlorophenyl)-3- azabicycl...)
Affinity DataIC50: 2.88nMAssay Description:The IC50 (effective concentration) of compounds on the human TRPA1 channel was determined using a FLIPR Tetra instrument. CHO cells expressing TRPA1 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/14/2021
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 452803BDBM452803(1-((3-((1S,5S,6R)-3- (4-fluorophenyl) bicyclo[3.1....)
Affinity DataIC50: 3nMAssay Description:The IC50 (effective concentration) of compounds on the human TRPA1 channel was determined using a FLIPR Tetra instrument. CHO cells expressing TRPA1 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/14/2021
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 452932BDBM452932(US10711004, Example 254 | US10711004, Example 282 ...)
Affinity DataIC50: 3.10nMAssay Description:The IC50 (effective concentration) of compounds on the human TRPA1 channel was determined using a FLIPR Tetra instrument. CHO cells expressing TRPA1 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/14/2021
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 452956BDBM452956(7-methyl-1-[[3- [(1S,5S,6R)-3-(1,3- benzothiazol-6...)
Affinity DataIC50: 3.10nMAssay Description:The IC50 (effective concentration) of compounds on the human TRPA1 channel was determined using a FLIPR Tetra instrument. CHO cells expressing TRPA1 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/14/2021
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 452770BDBM452770(1-((3-((1R,5S,6r)-3- (3,5-difluorophenyl)- 3-azabi...)
Affinity DataIC50: 3.10nMAssay Description:The IC50 (effective concentration) of compounds on the human TRPA1 channel was determined using a FLIPR Tetra instrument. CHO cells expressing TRPA1 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/14/2021
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 452786BDBM452786(1-methyl-6-((3- ((1S,5S,6R)-3- phenylbicyclo[3.1.0...)
Affinity DataIC50: 3.10nMAssay Description:The IC50 (effective concentration) of compounds on the human TRPA1 channel was determined using a FLIPR Tetra instrument. CHO cells expressing TRPA1 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/14/2021
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 452773BDBM452773(5-methyl-3-((3- ((1R,5S,6r)-3- phenyl-3- azabicycl...)
Affinity DataIC50: 3.5nMAssay Description:The IC50 (effective concentration) of compounds on the human TRPA1 channel was determined using a FLIPR Tetra instrument. CHO cells expressing TRPA1 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/14/2021
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 452817BDBM452817(6-((3-((1R,5S,6r)-3- (3-chlorophenyl)-3- azabicycl...)
Affinity DataIC50: 3.60nMAssay Description:The IC50 (effective concentration) of compounds on the human TRPA1 channel was determined using a FLIPR Tetra instrument. CHO cells expressing TRPA1 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/14/2021
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 452933BDBM452933(8-amino-7-methyl-1- [[3-[(1S,5S,6R)-3- phenyl-6-bi...)
Affinity DataIC50: 3.80nMAssay Description:The IC50 (effective concentration) of compounds on the human TRPA1 channel was determined using a FLIPR Tetra instrument. CHO cells expressing TRPA1 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/14/2021
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 452783BDBM452783(1-((3-((1R,5S,6r)-3- (3,4-difluorophenyl)- 3-azabi...)
Affinity DataIC50: 3.90nMAssay Description:The IC50 (effective concentration) of compounds on the human TRPA1 channel was determined using a FLIPR Tetra instrument. CHO cells expressing TRPA1 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/14/2021
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 452771BDBM452771(1-((3-((1S,5S,6R)-3- (3,4-difluorophenyl) bicyclo[...)
Affinity DataIC50: 3.90nMAssay Description:The IC50 (effective concentration) of compounds on the human TRPA1 channel was determined using a FLIPR Tetra instrument. CHO cells expressing TRPA1 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/14/2021
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 452851BDBM452851(3-((3-((1R,5S,6r)-3- (3-chlorophenyl)-3- azabicycl...)
Affinity DataIC50: 3.97nMAssay Description:The IC50 (effective concentration) of compounds on the human TRPA1 channel was determined using a FLIPR Tetra instrument. CHO cells expressing TRPA1 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/14/2021
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 452787BDBM452787(1-methyl-6-((3- ((1R,5R,6S)-3- phenylbicyclo[3.1.0...)
Affinity DataIC50: 4.10nMAssay Description:The IC50 (effective concentration) of compounds on the human TRPA1 channel was determined using a FLIPR Tetra instrument. CHO cells expressing TRPA1 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/14/2021
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 452939BDBM452939(7-amino-3-[[3- [(1R,5S)-3-(3- fluorophenyl)-3- aza...)
Affinity DataIC50: 4.30nMAssay Description:The IC50 (effective concentration) of compounds on the human TRPA1 channel was determined using a FLIPR Tetra instrument. CHO cells expressing TRPA1 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/14/2021
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 452914BDBM452914(1-((3-((1R,5S,6r)-3- (3-chloro-2-fluoro- phenyl)-3...)
Affinity DataIC50: 4.40nMAssay Description:The IC50 (effective concentration) of compounds on the human TRPA1 channel was determined using a FLIPR Tetra instrument. CHO cells expressing TRPA1 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/14/2021
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 452945BDBM452945(7-methyl-1-[[3- [(1R,5R,6S)-3-(1,3- benzoxazol-5-y...)
Affinity DataIC50: 4.40nMAssay Description:The IC50 (effective concentration) of compounds on the human TRPA1 channel was determined using a FLIPR Tetra instrument. CHO cells expressing TRPA1 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/14/2021
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 452947BDBM452947(7-methyl-1-[[3- [(1S,5S,6R)-3-(2,4- difluorophenyl...)
Affinity DataIC50: 4.60nMAssay Description:The IC50 (effective concentration) of compounds on the human TRPA1 channel was determined using a FLIPR Tetra instrument. CHO cells expressing TRPA1 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/14/2021
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 452760BDBM452760(US10711004, Example 82 | US10711004, Example 83 | ...)
Affinity DataIC50: 4.70nMAssay Description:The IC50 (effective concentration) of compounds on the human TRPA1 channel was determined using a FLIPR Tetra instrument. CHO cells expressing TRPA1 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/14/2021
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 452696BDBM452696(US10711004, Example 16 | 7-methyl-1-[[3- [(1R,5S,6...)
Affinity DataIC50: 4.80nMAssay Description:The IC50 (effective concentration) of compounds on the human TRPA1 channel was determined using a FLIPR Tetra instrument. CHO cells expressing TRPA1 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/14/2021
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 452772BDBM452772(1-((3-((1R,5R,6S)-3- (3,4-difluorophenyl) bicyclo[...)
Affinity DataIC50: 4.90nMAssay Description:The IC50 (effective concentration) of compounds on the human TRPA1 channel was determined using a FLIPR Tetra instrument. CHO cells expressing TRPA1 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/14/2021
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 452891BDBM452891(6-((3-((1R,5S,6r)-3- phenyl-3-azabicyclo [3.1.0]he...)
Affinity DataIC50: 5.10nMAssay Description:The IC50 (effective concentration) of compounds on the human TRPA1 channel was determined using a FLIPR Tetra instrument. CHO cells expressing TRPA1 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/14/2021
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 452774BDBM452774(6-((3-((1R,5S,6r)-3- (3-fluorophenyl)-3- azabicycl...)
Affinity DataIC50: 5.10nMAssay Description:The IC50 (effective concentration) of compounds on the human TRPA1 channel was determined using a FLIPR Tetra instrument. CHO cells expressing TRPA1 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/14/2021
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 452819BDBM452819(1-((3-((1S,5S,6R)-3- (4-chlorophenyl) bicyclo[3.1....)
Affinity DataIC50: 5.10nMAssay Description:The IC50 (effective concentration) of compounds on the human TRPA1 channel was determined using a FLIPR Tetra instrument. CHO cells expressing TRPA1 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/14/2021
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 452696BDBM452696(US10711004, Example 16 | 7-methyl-1-[[3- [(1R,5S,6...)
Affinity DataIC50: 5.20nMAssay Description:The IC50 (effective concentration) of compounds on the human TRPA1 channel was determined using a FLIPR Tetra instrument. CHO cells expressing TRPA1 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/14/2021
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 452917BDBM452917(7-amino-3-[[3- [(1S,5S,6R)-3-phenyl- 6-bicyclo[3.1...)
Affinity DataIC50: 5.30nMAssay Description:The IC50 (effective concentration) of compounds on the human TRPA1 channel was determined using a FLIPR Tetra instrument. CHO cells expressing TRPA1 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/14/2021
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 452961BDBM452961(2-fluoro-4-[(1R,5R,6S)- 6-[5-[(7-methyl-6-oxo- pur...)
Affinity DataIC50: 5.30nMAssay Description:The IC50 (effective concentration) of compounds on the human TRPA1 channel was determined using a FLIPR Tetra instrument. CHO cells expressing TRPA1 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/14/2021
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 452816BDBM452816(3-((3-((1R,5S,6r)-3- (4-chloropyridin-2-yl)- 3-aza...)
Affinity DataIC50: 5.5nMAssay Description:The IC50 (effective concentration) of compounds on the human TRPA1 channel was determined using a FLIPR Tetra instrument. CHO cells expressing TRPA1 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/14/2021
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 452926BDBM452926(1-[[3-[trans-3- [difluoro-(3- fluorophenyl)methyl]...)
Affinity DataIC50: 5.5nMAssay Description:The IC50 (effective concentration) of compounds on the human TRPA1 channel was determined using a FLIPR Tetra instrument. CHO cells expressing TRPA1 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/14/2021
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 452957BDBM452957(6-[[3-[(1R,5S)-3- (1,3-benzothiazol-6- yl)-3-azabi...)
Affinity DataIC50: 5.60nMAssay Description:The IC50 (effective concentration) of compounds on the human TRPA1 channel was determined using a FLIPR Tetra instrument. CHO cells expressing TRPA1 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/14/2021
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 452786BDBM452786(1-methyl-6-((3- ((1S,5S,6R)-3- phenylbicyclo[3.1.0...)
Affinity DataIC50: 6.12nMAssay Description:The IC50 (effective concentration) of compounds on the human TRPA1 channel was determined using a FLIPR Tetra instrument. CHO cells expressing TRPA1 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/14/2021
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 452891BDBM452891(6-((3-((1R,5S,6r)-3- phenyl-3-azabicyclo [3.1.0]he...)
Affinity DataIC50: 6.17nMAssay Description:The IC50 (effective concentration) of compounds on the human TRPA1 channel was determined using a FLIPR Tetra instrument. CHO cells expressing TRPA1 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/14/2021
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 452920BDBM452920(US10711004, Example 242 | 7-methyl-1-[[3- [(1R,5R,...)
Affinity DataIC50: 6.30nMAssay Description:The IC50 (effective concentration) of compounds on the human TRPA1 channel was determined using a FLIPR Tetra instrument. CHO cells expressing TRPA1 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/14/2021
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 452920BDBM452920(US10711004, Example 242 | 7-methyl-1-[[3- [(1R,5R,...)
Affinity DataIC50: 6.30nMAssay Description:The IC50 (effective concentration) of compounds on the human TRPA1 channel was determined using a FLIPR Tetra instrument. CHO cells expressing TRPA1 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/14/2021
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 452777BDBM452777(1-((3-((1R,5S,6r)-3- (2,5-difluorophenyl)- 3-azabi...)
Affinity DataIC50: 6.30nMAssay Description:The IC50 (effective concentration) of compounds on the human TRPA1 channel was determined using a FLIPR Tetra instrument. CHO cells expressing TRPA1 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/14/2021
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 452792BDBM452792(1-((3-((1S,5S,6R)-3- (3-fluorophenyl) bicyclo[3.1....)
Affinity DataIC50: 6.40nMAssay Description:The IC50 (effective concentration) of compounds on the human TRPA1 channel was determined using a FLIPR Tetra instrument. CHO cells expressing TRPA1 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/14/2021
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 452941BDBM452941(8-chloro-7-methyl-1- [[3-[(1R,5R,6S)-3- phenyl-6-b...)
Affinity DataIC50: 6.5nMAssay Description:The IC50 (effective concentration) of compounds on the human TRPA1 channel was determined using a FLIPR Tetra instrument. CHO cells expressing TRPA1 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/14/2021
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 452953BDBM452953(2-[[3-[(1R,5R,6S)-3- phenyl-6-bicyclo [3.1.0]hex-2...)
Affinity DataIC50: 6.5nMAssay Description:The IC50 (effective concentration) of compounds on the human TRPA1 channel was determined using a FLIPR Tetra instrument. CHO cells expressing TRPA1 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/14/2021
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 452934BDBM452934(4-[(1S,5S,6R)-6-[5- [(7-methyl-6-oxo- purin-1-yl)m...)
Affinity DataIC50: 6.60nMAssay Description:The IC50 (effective concentration) of compounds on the human TRPA1 channel was determined using a FLIPR Tetra instrument. CHO cells expressing TRPA1 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/14/2021
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 452900BDBM452900(1-((3-((1R,5S,6r)-3- (3-chloro-2,6-difluoro- pheny...)
Affinity DataIC50: 6.70nMAssay Description:The IC50 (effective concentration) of compounds on the human TRPA1 channel was determined using a FLIPR Tetra instrument. CHO cells expressing TRPA1 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/14/2021
Entry Details
US Patent

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