Compile Data Set for Download or QSAR
Report error Found 84 Enz. Inhib. hit(s) with all data for entry = 9277
TargetSodium channel protein type 9 subunit alpha(Human)
Purdue Pharma

US Patent
LigandChemical structure of BindingDB Monomer ID 454685BDBM454685(N-cyclohexyl-6-(1H-indol-5- yl)picolinamide | US10...)
Affinity DataIC50: 167nMAssay Description:In vitro assays were performed in a recombinant cell line expressing cDNA encoding the alpha subunit (Nav1.7, SCN9a, PN1, NE) of human Nav1.7 (Access...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2021
Entry Details
US Patent

TargetSodium channel protein type 9 subunit alpha(Human)
Purdue Pharma

US Patent
LigandChemical structure of BindingDB Monomer ID 454732BDBM454732(2-(1-(4-(trifluoromethyl)benzyl)-1H- indol-5-yl)th...)
Affinity DataIC50: 173nMAssay Description:In vitro assays were performed in a recombinant cell line expressing cDNA encoding the alpha subunit (Nav1.7, SCN9a, PN1, NE) of human Nav1.7 (Access...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2021
Entry Details
US Patent

TargetSodium channel protein type 9 subunit alpha(Human)
Purdue Pharma

US Patent
LigandChemical structure of BindingDB Monomer ID 454701BDBM454701((S)-1-(6-(1-(4- (trifluoromethyl)benzyl)-1H-indol-...)
Affinity DataIC50: 177nMAssay Description:In vitro assays were performed in a recombinant cell line expressing cDNA encoding the alpha subunit (Nav1.7, SCN9a, PN1, NE) of human Nav1.7 (Access...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2021
Entry Details
US Patent

TargetSodium channel protein type 9 subunit alpha(Human)
Purdue Pharma

US Patent
LigandChemical structure of BindingDB Monomer ID 454691BDBM454691(N-(cyclohexylmethyl)-6-(1H-indol-5- yl)picolinamid...)
Affinity DataIC50: 180nMAssay Description:In vitro assays were performed in a recombinant cell line expressing cDNA encoding the alpha subunit (Nav1.7, SCN9a, PN1, NE) of human Nav1.7 (Access...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2021
Entry Details
US Patent

TargetSodium channel protein type 9 subunit alpha(Human)
Purdue Pharma

US Patent
LigandChemical structure of BindingDB Monomer ID 454672BDBM454672(6-(1-(4-(trifluoromethyl)benzyl)-1H- indol-5-yl)pi...)
Affinity DataIC50: 230nMAssay Description:In vitro assays were performed in a recombinant cell line expressing cDNA encoding the alpha subunit (Nav1.7, SCN9a, PN1, NE) of human Nav1.7 (Access...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2021
Entry Details
US Patent

TargetSodium channel protein type 9 subunit alpha(Human)
Purdue Pharma

US Patent
LigandChemical structure of BindingDB Monomer ID 454660BDBM454660(6-(1H-indol-5-yl)-N-(4- (trifluoromethyl)phenyl)pi...)
Affinity DataIC50: 233nMAssay Description:In vitro assays were performed in a recombinant cell line expressing cDNA encoding the alpha subunit (Nav1.7, SCN9a, PN1, NE) of human Nav1.7 (Access...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2021
Entry Details
US Patent

TargetSodium channel protein type 9 subunit alpha(Human)
Purdue Pharma

US Patent
LigandChemical structure of BindingDB Monomer ID 454674BDBM454674(6-(1-(cyclohexylmethyl)-1H-indol-5- yl)picolinamid...)
Affinity DataIC50: 237nMAssay Description:In vitro assays were performed in a recombinant cell line expressing cDNA encoding the alpha subunit (Nav1.7, SCN9a, PN1, NE) of human Nav1.7 (Access...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2021
Entry Details
US Patent

TargetSodium channel protein type 9 subunit alpha(Human)
Purdue Pharma

US Patent
LigandChemical structure of BindingDB Monomer ID 454698BDBM454698((S)-1-(6-(1-(4- (trifluoromethyl)benzyl)-1H- pyrro...)
Affinity DataKi:  286nMAssay Description:The hNav1.7 expressing HEK-293 cells are plated on 35 mm culture dishes pre-coated with poly-D-lysine in standard DMEM culture media (Mediatech, Inc....More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2021
Entry Details
US Patent

TargetSodium channel protein type 9 subunit alpha(Human)
Purdue Pharma

US Patent
LigandChemical structure of BindingDB Monomer ID 454682BDBM454682(6-(1-isobutyl-1H-indol-5- yl)picolinamide | US1073...)
Affinity DataIC50: 308nMAssay Description:In vitro assays were performed in a recombinant cell line expressing cDNA encoding the alpha subunit (Nav1.7, SCN9a, PN1, NE) of human Nav1.7 (Access...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2021
Entry Details
US Patent

TargetSodium channel protein type 9 subunit alpha(Human)
Purdue Pharma

US Patent
LigandChemical structure of BindingDB Monomer ID 454665BDBM454665(6-(1-isobutyl-1H-indol-5-yl)-N-(1,2,4- thiadiazol-...)
Affinity DataKi:  322nMAssay Description:The hNav1.7 expressing HEK-293 cells are plated on 35 mm culture dishes pre-coated with poly-D-lysine in standard DMEM culture media (Mediatech, Inc....More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2021
Entry Details
US Patent

TargetSodium channel protein type 9 subunit alpha(Human)
Purdue Pharma

US Patent
LigandChemical structure of BindingDB Monomer ID 454728BDBM454728((2R,3S)-3-(6-(1-(cyclohexylmethyl)- 1H-indol-5-yl)...)
Affinity DataIC50: 402nMAssay Description:In vitro assays were performed in a recombinant cell line expressing cDNA encoding the alpha subunit (Nav1.7, SCN9a, PN1, NE) of human Nav1.7 (Access...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2021
Entry Details
US Patent

TargetSodium channel protein type 9 subunit alpha(Human)
Purdue Pharma

US Patent
LigandChemical structure of BindingDB Monomer ID 454665BDBM454665(6-(1-isobutyl-1H-indol-5-yl)-N-(1,2,4- thiadiazol-...)
Affinity DataIC50: 514nMAssay Description:In vitro assays were performed in a recombinant cell line expressing cDNA encoding the alpha subunit (Nav1.7, SCN9a, PN1, NE) of human Nav1.7 (Access...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2021
Entry Details
US Patent

TargetSodium channel protein type 9 subunit alpha(Human)
Purdue Pharma

US Patent
LigandChemical structure of BindingDB Monomer ID 454699BDBM454699((S)-1-(6-(1-(4- (trifluoromethyl)benzyl)-1H-indazo...)
Affinity DataKi:  534nMAssay Description:The hNav1.7 expressing HEK-293 cells are plated on 35 mm culture dishes pre-coated with poly-D-lysine in standard DMEM culture media (Mediatech, Inc....More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2021
Entry Details
US Patent

TargetSodium channel protein type 9 subunit alpha(Human)
Purdue Pharma

US Patent
LigandChemical structure of BindingDB Monomer ID 454673BDBM454673(6-(1-((4-(trifluoromethyl)phenyl) sulfonyl)-1H-ind...)
Affinity DataIC50: 658nMAssay Description:In vitro assays were performed in a recombinant cell line expressing cDNA encoding the alpha subunit (Nav1.7, SCN9a, PN1, NE) of human Nav1.7 (Access...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2021
Entry Details
US Patent

TargetSodium channel protein type 9 subunit alpha(Human)
Purdue Pharma

US Patent
LigandChemical structure of BindingDB Monomer ID 454726BDBM454726(US10730866, Compound 150 | (2R,3S)-2,3-dihydroxy-3...)
Affinity DataKi:  678nMAssay Description:The hNav1.7 expressing HEK-293 cells are plated on 35 mm culture dishes pre-coated with poly-D-lysine in standard DMEM culture media (Mediatech, Inc....More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2021
Entry Details
US Patent

TargetSodium channel protein type 9 subunit alpha(Human)
Purdue Pharma

US Patent
LigandChemical structure of BindingDB Monomer ID 454697BDBM454697(6-(1-(4-(trifluoromethyl)benzyl)-1H- indazol-5-yl)...)
Affinity DataKi:  700nMAssay Description:The hNav1.7 expressing HEK-293 cells are plated on 35 mm culture dishes pre-coated with poly-D-lysine in standard DMEM culture media (Mediatech, Inc....More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2021
Entry Details
US Patent

TargetSodium channel protein type 9 subunit alpha(Human)
Purdue Pharma

US Patent
LigandChemical structure of BindingDB Monomer ID 454703BDBM454703((S)-1-(6-(1-(piperidin-1-ylsulfonyl)- 1H-indol-5-y...)
Affinity DataIC50: 716nMAssay Description:In vitro assays were performed in a recombinant cell line expressing cDNA encoding the alpha subunit (Nav1.7, SCN9a, PN1, NE) of human Nav1.7 (Access...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2021
Entry Details
US Patent

TargetSodium channel protein type 9 subunit alpha(Human)
Purdue Pharma

US Patent
LigandChemical structure of BindingDB Monomer ID 454727BDBM454727((2R,3S)-2,3-dihydroxy-3-(6-(1-(4- (trifluoromethyl...)
Affinity DataIC50: 773nMAssay Description:In vitro assays were performed in a recombinant cell line expressing cDNA encoding the alpha subunit (Nav1.7, SCN9a, PN1, NE) of human Nav1.7 (Access...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2021
Entry Details
US Patent

TargetSodium channel protein type 9 subunit alpha(Human)
Purdue Pharma

US Patent
LigandChemical structure of BindingDB Monomer ID 454690BDBM454690(6-(benzofuran-5-yl)-N-(4- (trifluoromethyl)phenyl)...)
Affinity DataIC50: 782nMAssay Description:In vitro assays were performed in a recombinant cell line expressing cDNA encoding the alpha subunit (Nav1.7, SCN9a, PN1, NE) of human Nav1.7 (Access...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2021
Entry Details
US Patent

TargetSodium channel protein type 9 subunit alpha(Human)
Purdue Pharma

US Patent
LigandChemical structure of BindingDB Monomer ID 454676BDBM454676(6-(1-(4-fluorobenzyl)-1H-indol-5- yl)picolinamide ...)
Affinity DataIC50: 801nMAssay Description:In vitro assays were performed in a recombinant cell line expressing cDNA encoding the alpha subunit (Nav1.7, SCN9a, PN1, NE) of human Nav1.7 (Access...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2021
Entry Details
US Patent

TargetSodium channel protein type 9 subunit alpha(Human)
Purdue Pharma

US Patent
LigandChemical structure of BindingDB Monomer ID 454697BDBM454697(6-(1-(4-(trifluoromethyl)benzyl)-1H- indazol-5-yl)...)
Affinity DataIC50: 897nMAssay Description:In vitro assays were performed in a recombinant cell line expressing cDNA encoding the alpha subunit (Nav1.7, SCN9a, PN1, NE) of human Nav1.7 (Access...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2021
Entry Details
US Patent

TargetSodium channel protein type 9 subunit alpha(Human)
Purdue Pharma

US Patent
LigandChemical structure of BindingDB Monomer ID 454675BDBM454675(6-(1-(cyclohexylsulfonyl)-1H-indol-5- yl)picolinam...)
Affinity DataIC50: 927nMAssay Description:In vitro assays were performed in a recombinant cell line expressing cDNA encoding the alpha subunit (Nav1.7, SCN9a, PN1, NE) of human Nav1.7 (Access...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2021
Entry Details
US Patent

TargetSodium channel protein type 9 subunit alpha(Human)
Purdue Pharma

US Patent
LigandChemical structure of BindingDB Monomer ID 454711BDBM454711((S)-6-(1,2-dihydroxyethyl)-4-(1-(4- (trifluorometh...)
Affinity DataKi:  1.03E+3nMAssay Description:The hNav1.7 expressing HEK-293 cells are plated on 35 mm culture dishes pre-coated with poly-D-lysine in standard DMEM culture media (Mediatech, Inc....More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2021
Entry Details
US Patent

TargetSodium channel protein type 9 subunit alpha(Human)
Purdue Pharma

US Patent
LigandChemical structure of BindingDB Monomer ID 454699BDBM454699((S)-1-(6-(1-(4- (trifluoromethyl)benzyl)-1H-indazo...)
Affinity DataIC50: 1.09E+3nMAssay Description:In vitro assays were performed in a recombinant cell line expressing cDNA encoding the alpha subunit (Nav1.7, SCN9a, PN1, NE) of human Nav1.7 (Access...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2021
Entry Details
US Patent

TargetSodium channel protein type 9 subunit alpha(Human)
Purdue Pharma

US Patent
LigandChemical structure of BindingDB Monomer ID 454678BDBM454678(6-(1-(2-cyclohexylethyl)-1H-indol-5- yl)picolinami...)
Affinity DataIC50: 1.12E+3nMAssay Description:In vitro assays were performed in a recombinant cell line expressing cDNA encoding the alpha subunit (Nav1.7, SCN9a, PN1, NE) of human Nav1.7 (Access...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2021
Entry Details
US Patent

TargetSodium channel protein type 9 subunit alpha(Human)
Purdue Pharma

US Patent
LigandChemical structure of BindingDB Monomer ID 454693BDBM454693(N-cyclopentyl-6-(1H-indol-5- yl)picolinamide | US1...)
Affinity DataIC50: 1.21E+3nMAssay Description:In vitro assays were performed in a recombinant cell line expressing cDNA encoding the alpha subunit (Nav1.7, SCN9a, PN1, NE) of human Nav1.7 (Access...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2021
Entry Details
US Patent

TargetSodium channel protein type 9 subunit alpha(Human)
Purdue Pharma

US Patent
LigandChemical structure of BindingDB Monomer ID 454687BDBM454687((S)-2-(1H-indol-5-yl)-6-((2- oxopyrrolidin-3-yl)am...)
Affinity DataKi:  1.28E+3nMAssay Description:The hNav1.7 expressing HEK-293 cells are plated on 35 mm culture dishes pre-coated with poly-D-lysine in standard DMEM culture media (Mediatech, Inc....More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2021
Entry Details
US Patent

TargetSodium channel protein type 9 subunit alpha(Human)
Purdue Pharma

US Patent
LigandChemical structure of BindingDB Monomer ID 454698BDBM454698((S)-1-(6-(1-(4- (trifluoromethyl)benzyl)-1H- pyrro...)
Affinity DataIC50: 1.33E+3nMAssay Description:In vitro assays were performed in a recombinant cell line expressing cDNA encoding the alpha subunit (Nav1.7, SCN9a, PN1, NE) of human Nav1.7 (Access...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2021
Entry Details
US Patent

TargetSodium channel protein type 9 subunit alpha(Human)
Purdue Pharma

US Patent
LigandChemical structure of BindingDB Monomer ID 454726BDBM454726(US10730866, Compound 150 | (2R,3S)-2,3-dihydroxy-3...)
Affinity DataIC50: 1.38E+3nMAssay Description:In vitro assays were performed in a recombinant cell line expressing cDNA encoding the alpha subunit (Nav1.7, SCN9a, PN1, NE) of human Nav1.7 (Access...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2021
Entry Details
US Patent

TargetSodium channel protein type 9 subunit alpha(Human)
Purdue Pharma

US Patent
LigandChemical structure of BindingDB Monomer ID 454711BDBM454711((S)-6-(1,2-dihydroxyethyl)-4-(1-(4- (trifluorometh...)
Affinity DataIC50: 1.52E+3nMAssay Description:In vitro assays were performed in a recombinant cell line expressing cDNA encoding the alpha subunit (Nav1.7, SCN9a, PN1, NE) of human Nav1.7 (Access...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2021
Entry Details
US Patent

TargetSodium channel protein type 9 subunit alpha(Human)
Purdue Pharma

US Patent
LigandChemical structure of BindingDB Monomer ID 454667BDBM454667((S)-6-((2-oxopyrrolidin-3-yl)amino)- 2-(1-(4-(trif...)
Affinity DataKi:  1.54E+3nMAssay Description:The hNav1.7 expressing HEK-293 cells are plated on 35 mm culture dishes pre-coated with poly-D-lysine in standard DMEM culture media (Mediatech, Inc....More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2021
Entry Details
US Patent

TargetSodium channel protein type 9 subunit alpha(Human)
Purdue Pharma

US Patent
LigandChemical structure of BindingDB Monomer ID 454667BDBM454667((S)-6-((2-oxopyrrolidin-3-yl)amino)- 2-(1-(4-(trif...)
Affinity DataIC50: 1.72E+3nMAssay Description:In vitro assays were performed in a recombinant cell line expressing cDNA encoding the alpha subunit (Nav1.7, SCN9a, PN1, NE) of human Nav1.7 (Access...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2021
Entry Details
US Patent

TargetSodium channel protein type 9 subunit alpha(Human)
Purdue Pharma

US Patent
LigandChemical structure of BindingDB Monomer ID 454710BDBM454710((R)-6-(1,2-dihydroxyethyl)-4-(1-(4- (trifluorometh...)
Affinity DataIC50: 1.74E+3nMAssay Description:In vitro assays were performed in a recombinant cell line expressing cDNA encoding the alpha subunit (Nav1.7, SCN9a, PN1, NE) of human Nav1.7 (Access...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2021
Entry Details
US Patent

TargetSodium channel protein type 9 subunit alpha(Human)
Purdue Pharma

US Patent
LigandChemical structure of BindingDB Monomer ID 454687BDBM454687((S)-2-(1H-indol-5-yl)-6-((2- oxopyrrolidin-3-yl)am...)
Affinity DataIC50: 1.83E+3nMAssay Description:In vitro assays were performed in a recombinant cell line expressing cDNA encoding the alpha subunit (Nav1.7, SCN9a, PN1, NE) of human Nav1.7 (Access...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2021
Entry Details
US Patent

TargetSodium channel protein type 9 subunit alpha(Human)
Purdue Pharma

US Patent
LigandChemical structure of BindingDB Monomer ID 454708BDBM454708((R)-4-(1,2-dihydroxyethyl)-6-(1-(4- (trifluorometh...)
Affinity DataIC50: 1.91E+3nMAssay Description:In vitro assays were performed in a recombinant cell line expressing cDNA encoding the alpha subunit (Nav1.7, SCN9a, PN1, NE) of human Nav1.7 (Access...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2021
Entry Details
US Patent

TargetSodium channel protein type 9 subunit alpha(Human)
Purdue Pharma

US Patent
LigandChemical structure of BindingDB Monomer ID 454666BDBM454666((S)-2-(2-(2,4-dimethoxyphenyl)-1-(4- fluorophenyl)...)
Affinity DataIC50: 2.03E+3nMAssay Description:In vitro assays were performed in a recombinant cell line expressing cDNA encoding the alpha subunit (Nav1.7, SCN9a, PN1, NE) of human Nav1.7 (Access...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2021
Entry Details
US Patent

TargetSodium channel protein type 9 subunit alpha(Human)
Purdue Pharma

US Patent
LigandChemical structure of BindingDB Monomer ID 454708BDBM454708((R)-4-(1,2-dihydroxyethyl)-6-(1-(4- (trifluorometh...)
Affinity DataKi:  2.03E+3nMAssay Description:The hNav1.7 expressing HEK-293 cells are plated on 35 mm culture dishes pre-coated with poly-D-lysine in standard DMEM culture media (Mediatech, Inc....More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2021
Entry Details
US Patent

TargetSodium channel protein type 9 subunit alpha(Human)
Purdue Pharma

US Patent
LigandChemical structure of BindingDB Monomer ID 454709BDBM454709((S)-4-(1,2-dihydroxyethyl)-6-(1-(4- (trifluorometh...)
Affinity DataIC50: 2.37E+3nMAssay Description:In vitro assays were performed in a recombinant cell line expressing cDNA encoding the alpha subunit (Nav1.7, SCN9a, PN1, NE) of human Nav1.7 (Access...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2021
Entry Details
US Patent

TargetSodium channel protein type 9 subunit alpha(Human)
Purdue Pharma

US Patent
LigandChemical structure of BindingDB Monomer ID 454724BDBM454724((S)-6-(3-(((2-oxopyrrolidin-3- yl)amino)methyl)-1-...)
Affinity DataIC50: 2.54E+3nMAssay Description:In vitro assays were performed in a recombinant cell line expressing cDNA encoding the alpha subunit (Nav1.7, SCN9a, PN1, NE) of human Nav1.7 (Access...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2021
Entry Details
US Patent

TargetSodium channel protein type 9 subunit alpha(Human)
Purdue Pharma

US Patent
LigandChemical structure of BindingDB Monomer ID 454726BDBM454726(US10730866, Compound 150 | (2R,3S)-2,3-dihydroxy-3...)
Affinity DataIC50: 2.62E+3nMAssay Description:In vitro assays were performed in a recombinant cell line expressing cDNA encoding the alpha subunit (Nav1.7, SCN9a, PN1, NE) of human Nav1.7 (Access...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2021
Entry Details
US Patent

TargetSodium channel protein type 9 subunit alpha(Human)
Purdue Pharma

US Patent
LigandChemical structure of BindingDB Monomer ID 454686BDBM454686(6-(1H-indazol-5-yl)-N-(4- (trifluoromethyl)phenyl)...)
Affinity DataIC50: 2.70E+3nMAssay Description:In vitro assays were performed in a recombinant cell line expressing cDNA encoding the alpha subunit (Nav1.7, SCN9a, PN1, NE) of human Nav1.7 (Access...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2021
Entry Details
US Patent

TargetSodium channel protein type 9 subunit alpha(Human)
Purdue Pharma

US Patent
LigandChemical structure of BindingDB Monomer ID 454684BDBM454684(6-(1-methyl-1H-indol-5-yl)-N-(4- (trifluoromethyl)...)
Affinity DataIC50: 3.03E+3nMAssay Description:In vitro assays were performed in a recombinant cell line expressing cDNA encoding the alpha subunit (Nav1.7, SCN9a, PN1, NE) of human Nav1.7 (Access...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2021
Entry Details
US Patent

TargetSodium channel protein type 9 subunit alpha(Human)
Purdue Pharma

US Patent
LigandChemical structure of BindingDB Monomer ID 454702BDBM454702((S)-1-(6-(1-(4- (trifluoromethyl)benzyl)-1H- benzo...)
Affinity DataIC50: 3.44E+3nMAssay Description:In vitro assays were performed in a recombinant cell line expressing cDNA encoding the alpha subunit (Nav1.7, SCN9a, PN1, NE) of human Nav1.7 (Access...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2021
Entry Details
US Patent

TargetSodium channel protein type 9 subunit alpha(Human)
Purdue Pharma

US Patent
LigandChemical structure of BindingDB Monomer ID 454671BDBM454671((S)-1-(2-(1-(4- (trifluoromethyl)phenyl)-1H- benzo...)
Affinity DataIC50: 3.51E+3nMAssay Description:In vitro assays were performed in a recombinant cell line expressing cDNA encoding the alpha subunit (Nav1.7, SCN9a, PN1, NE) of human Nav1.7 (Access...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2021
Entry Details
US Patent

TargetSodium channel protein type 9 subunit alpha(Human)
Purdue Pharma

US Patent
LigandChemical structure of BindingDB Monomer ID 454718BDBM454718(6-amino-2-(benzofuran-5-yl)-N-(4- (trifluoromethyl...)
Affinity DataIC50: 3.66E+3nMAssay Description:In vitro assays were performed in a recombinant cell line expressing cDNA encoding the alpha subunit (Nav1.7, SCN9a, PN1, NE) of human Nav1.7 (Access...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2021
Entry Details
US Patent

TargetSodium channel protein type 9 subunit alpha(Human)
Purdue Pharma

US Patent
LigandChemical structure of BindingDB Monomer ID 454704BDBM454704((S)-6-((1-amino-1-oxopropan-2- yl)amino)-2-(1-(4- ...)
Affinity DataIC50: 4.12E+3nMAssay Description:In vitro assays were performed in a recombinant cell line expressing cDNA encoding the alpha subunit (Nav1.7, SCN9a, PN1, NE) of human Nav1.7 (Access...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2021
Entry Details
US Patent

TargetSodium channel protein type 9 subunit alpha(Human)
Purdue Pharma

US Patent
LigandChemical structure of BindingDB Monomer ID 454669BDBM454669((S)-6-((1-amino-1-oxopropan-2- yl)amino)-2-(1-isob...)
Affinity DataIC50: 4.19E+3nMAssay Description:In vitro assays were performed in a recombinant cell line expressing cDNA encoding the alpha subunit (Nav1.7, SCN9a, PN1, NE) of human Nav1.7 (Access...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2021
Entry Details
US Patent

TargetSodium channel protein type 9 subunit alpha(Human)
Purdue Pharma

US Patent
LigandChemical structure of BindingDB Monomer ID 454705BDBM454705((S)-6-((1-amino-1-oxopropan-2- yl)amino)-2-(1-(cyc...)
Affinity DataIC50: 4.43E+3nMAssay Description:In vitro assays were performed in a recombinant cell line expressing cDNA encoding the alpha subunit (Nav1.7, SCN9a, PN1, NE) of human Nav1.7 (Access...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2021
Entry Details
US Patent

TargetSodium channel protein type 9 subunit alpha(Human)
Purdue Pharma

US Patent
LigandChemical structure of BindingDB Monomer ID 454700BDBM454700((S)-1-(6-(2-(4- (trifluoromethyl)benzyl)-2H-indazo...)
Affinity DataIC50: 4.68E+3nMAssay Description:In vitro assays were performed in a recombinant cell line expressing cDNA encoding the alpha subunit (Nav1.7, SCN9a, PN1, NE) of human Nav1.7 (Access...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2021
Entry Details
US Patent

TargetSodium channel protein type 9 subunit alpha(Human)
Purdue Pharma

US Patent
LigandChemical structure of BindingDB Monomer ID 454696BDBM454696((S)-6-(1H-indol-5-yl)-4-((2- oxopyrrolidin-3-yl)am...)
Affinity DataIC50: 4.89E+3nMAssay Description:In vitro assays were performed in a recombinant cell line expressing cDNA encoding the alpha subunit (Nav1.7, SCN9a, PN1, NE) of human Nav1.7 (Access...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2021
Entry Details
US Patent

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