Compile Data Set for Download or QSAR
Report error Found 867 Enz. Inhib. hit(s) with all data for entry = 9283
TargetTyrosine-protein kinase JAK2(Human)
Array Biopharma

US Patent
LigandChemical structure of BindingDB Monomer ID 325372BDBM325372(N-methyl-4-(4-(4-(1- (pentan-3-yl)-1H-pyrazol- 4-y...)
Affinity DataIC50: 10nMAssay Description:Compounds of Formula I were screened for their ability to inhibit JAK2 using the general enzyme inhibition assay method, in which the assay mixture c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2021
Entry Details
US Patent

TargetTyrosine-protein kinase JAK2(Human)
Array Biopharma

US Patent
LigandChemical structure of BindingDB Monomer ID 325501BDBM325501(US10189845, Example 164B | US10189845, Example 163...)
Affinity DataIC50: 10nMAssay Description:Compounds of Formula I were screened for their ability to inhibit JAK2 using the general enzyme inhibition assay method, in which the assay mixture c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2021
Entry Details
US Patent

TargetTyrosine-protein kinase JAK2(Human)
Array Biopharma

US Patent
LigandChemical structure of BindingDB Monomer ID 325371BDBM325371(2-methoxy-1-(4-(4-(4-(1- (pentan-3-yl)-1H-pyrazol-...)
Affinity DataIC50: 10nMAssay Description:Compounds of Formula I were screened for their ability to inhibit JAK2 using the general enzyme inhibition assay method, in which the assay mixture c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2021
Entry Details
US Patent

TargetNon-receptor tyrosine-protein kinase TYK2(Human)
Array Biopharma

US Patent
LigandChemical structure of BindingDB Monomer ID 325371BDBM325371(2-methoxy-1-(4-(4-(4-(1- (pentan-3-yl)-1H-pyrazol-...)
Affinity DataIC50: 10nMAssay Description:Compounds of Formula I were screened for their ability to inhibit Tyk2 using the general enzyme inhibition assay method, in which the assay mixture c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2021
Entry Details
US Patent

TargetTyrosine-protein kinase JAK2(Human)
Array Biopharma

US Patent
LigandChemical structure of BindingDB Monomer ID 325370BDBM325370(6-(1-(1- (methylsulfonyl)piperidin- 4-yl)-1H-pyraz...)
Affinity DataIC50: 10nMAssay Description:Compounds of Formula I were screened for their ability to inhibit JAK2 using the general enzyme inhibition assay method, in which the assay mixture c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2021
Entry Details
US Patent

TargetNon-receptor tyrosine-protein kinase TYK2(Human)
Array Biopharma

US Patent
LigandChemical structure of BindingDB Monomer ID 325500BDBM325500((1s,3s)-1-methyl-3-(4-(4-(1-(pentan-3-yl)-1H-pyraz...)
Affinity DataIC50: 10nMAssay Description:Compounds of Formula I were screened for their ability to inhibit Tyk2 using the general enzyme inhibition assay method, in which the assay mixture c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2021
Entry Details
US Patent

TargetNon-receptor tyrosine-protein kinase TYK2(Human)
Array Biopharma

US Patent
LigandChemical structure of BindingDB Monomer ID 325370BDBM325370(6-(1-(1- (methylsulfonyl)piperidin- 4-yl)-1H-pyraz...)
Affinity DataIC50: 10nMAssay Description:Compounds of Formula I were screened for their ability to inhibit Tyk2 using the general enzyme inhibition assay method, in which the assay mixture c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2021
Entry Details
US Patent

TargetTyrosine-protein kinase JAK2(Human)
Array Biopharma

US Patent
LigandChemical structure of BindingDB Monomer ID 325369BDBM325369(1-(4-(4-(4-(1-(pentan-3-yl)-1H-pyrazol-4-yl)pyrazo...)
Affinity DataIC50: 10nMAssay Description:Compounds of Formula I were screened for their ability to inhibit JAK2 using the general enzyme inhibition assay method, in which the assay mixture c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2021
Entry Details
US Patent

TargetTyrosine-protein kinase JAK2(Human)
Array Biopharma

US Patent
LigandChemical structure of BindingDB Monomer ID 325386BDBM325386(4-(1-(3-ethyl-1-((trifluoromethyl)sulfonyl)azetidi...)
Affinity DataIC50: 10nMAssay Description:Compounds of Formula I were screened for their ability to inhibit JAK2 using the general enzyme inhibition assay method, in which the assay mixture c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2021
Entry Details
US Patent

TargetNon-receptor tyrosine-protein kinase TYK2(Human)
Array Biopharma

US Patent
LigandChemical structure of BindingDB Monomer ID 325515BDBM325515((1- hydroxycyclopropyl)(3- (4-(4-(1-(pentan-3-yl)-...)
Affinity DataIC50: 10nMAssay Description:Compounds of Formula I were screened for their ability to inhibit Tyk2 using the general enzyme inhibition assay method, in which the assay mixture c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2021
Entry Details
US Patent

TargetNon-receptor tyrosine-protein kinase TYK2(Human)
Array Biopharma

US Patent
LigandChemical structure of BindingDB Monomer ID 325386BDBM325386(4-(1-(3-ethyl-1-((trifluoromethyl)sulfonyl)azetidi...)
Affinity DataIC50: 10nMAssay Description:Compounds of Formula I were screened for their ability to inhibit Tyk2 using the general enzyme inhibition assay method, in which the assay mixture c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2021
Entry Details
US Patent

TargetNon-receptor tyrosine-protein kinase TYK2(Human)
Array Biopharma

US Patent
LigandChemical structure of BindingDB Monomer ID 325514BDBM325514(2-hydroxy-2-methyl-1-(3- (4-(4-(1-(pentan-3-yl)- 1...)
Affinity DataIC50: 10nMAssay Description:Compounds of Formula I were screened for their ability to inhibit Tyk2 using the general enzyme inhibition assay method, in which the assay mixture c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2021
Entry Details
US Patent

TargetTyrosine-protein kinase JAK2(Human)
Array Biopharma

US Patent
LigandChemical structure of BindingDB Monomer ID 325545BDBM325545(US10189845, Example 207A | US10730880, Example 207...)
Affinity DataIC50: 10nMAssay Description:Compounds of Formula I were screened for their ability to inhibit JAK2 using the general enzyme inhibition assay method, in which the assay mixture c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2021
Entry Details
US Patent

TargetTyrosine-protein kinase JAK2(Human)
Array Biopharma

US Patent
LigandChemical structure of BindingDB Monomer ID 325351BDBM325351(3-(4-(4-(1-(pentan-3-yl)-1H- pyrazol-4-yl)pyrazolo...)
Affinity DataIC50: 10nMAssay Description:Compounds of Formula I were screened for their ability to inhibit JAK2 using the general enzyme inhibition assay method, in which the assay mixture c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2021
Entry Details
US Patent

TargetTyrosine-protein kinase JAK2(Human)
Array Biopharma

US Patent
LigandChemical structure of BindingDB Monomer ID 455371BDBM455371(US10730880, Example 37 | 6-(1-(1-(methylsulfonyl)a...)
Affinity DataIC50: 10nMAssay Description:Compounds of Formula I were screened for their ability to inhibit JAK2 using the general enzyme inhibition assay method, in which the assay mixture c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2021
Entry Details
US Patent

TargetNon-receptor tyrosine-protein kinase TYK2(Human)
Array Biopharma

US Patent
LigandChemical structure of BindingDB Monomer ID 325457BDBM325457(cis-3-(4-(4-(1-(pentan-3- yl)-1H-pyrazol-4- yl)pyr...)
Affinity DataIC50: 10nMAssay Description:Compounds of Formula I were screened for their ability to inhibit Tyk2 using the general enzyme inhibition assay method, in which the assay mixture c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2021
Entry Details
US Patent

TargetNon-receptor tyrosine-protein kinase TYK2(Human)
Array Biopharma

US Patent
LigandChemical structure of BindingDB Monomer ID 325424BDBM325424((S)-3-(4-(4-(1-((S)- pentan-2-yl)-1H-pyrazol- 4-yl...)
Affinity DataIC50: 10nMAssay Description:Compounds of Formula I were screened for their ability to inhibit Tyk2 using the general enzyme inhibition assay method, in which the assay mixture c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2021
Entry Details
US Patent

TargetTyrosine-protein kinase JAK2(Human)
Array Biopharma

US Patent
LigandChemical structure of BindingDB Monomer ID 325456BDBM325456(trans-4-(4-(4-(1-(pentan-3-yl)-1H-pyrazol-4-yl)pyr...)
Affinity DataIC50: 10nMAssay Description:Compounds of Formula I were screened for their ability to inhibit JAK2 using the general enzyme inhibition assay method, in which the assay mixture c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2021
Entry Details
US Patent

TargetTyrosine-protein kinase JAK2(Human)
Array Biopharma

US Patent
LigandChemical structure of BindingDB Monomer ID 325374BDBM325374(2-amino-1-(4-(4-(4-(1-(pentan-3-yl)-1H-pyrazol-4-y...)
Affinity DataIC50: 10nMAssay Description:Compounds of Formula I were screened for their ability to inhibit JAK2 using the general enzyme inhibition assay method, in which the assay mixture c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2021
Entry Details
US Patent

TargetTyrosine-protein kinase JAK2(Human)
Array Biopharma

US Patent
LigandChemical structure of BindingDB Monomer ID 325423BDBM325423((R)-2-(4-(4-(1-(sec- butyl)-1H-pyrazol-4- yl)pyraz...)
Affinity DataIC50: 10nMAssay Description:Compounds of Formula I were screened for their ability to inhibit JAK2 using the general enzyme inhibition assay method, in which the assay mixture c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2021
Entry Details
US Patent

TargetNon-receptor tyrosine-protein kinase TYK2(Human)
Array Biopharma

US Patent
LigandChemical structure of BindingDB Monomer ID 325374BDBM325374(2-amino-1-(4-(4-(4-(1-(pentan-3-yl)-1H-pyrazol-4-y...)
Affinity DataIC50: 10nMAssay Description:Compounds of Formula I were screened for their ability to inhibit Tyk2 using the general enzyme inhibition assay method, in which the assay mixture c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2021
Entry Details
US Patent

TargetTyrosine-protein kinase JAK2(Human)
Array Biopharma

US Patent
LigandChemical structure of BindingDB Monomer ID 325470BDBM325470(US10189845, Example 133B | US10189845, Example 132...)
Affinity DataIC50: 10nMAssay Description:Compounds of Formula I were screened for their ability to inhibit JAK2 using the general enzyme inhibition assay method, in which the assay mixture c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2021
Entry Details
US Patent

TargetTyrosine-protein kinase JAK2(Human)
Array Biopharma

US Patent
LigandChemical structure of BindingDB Monomer ID 325348BDBM325348(N,N-dimethyl-2-(4-(4-(1- (pentan-3-yl)-1H-pyrazol-...)
Affinity DataIC50: 55nMAssay Description:Compounds of Formula I were screened for their ability to inhibit JAK2 using the general enzyme inhibition assay method, in which the assay mixture c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2021
Entry Details
US Patent

TargetNon-receptor tyrosine-protein kinase TYK2(Human)
Array Biopharma

US Patent
LigandChemical structure of BindingDB Monomer ID 325478BDBM325478((R)-1-(2-(4-(4-(1-(pentan-3- yl)-1H-pyrazol-4- yl)...)
Affinity DataIC50: 55nMAssay Description:Compounds of Formula I were screened for their ability to inhibit Tyk2 using the general enzyme inhibition assay method, in which the assay mixture c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2021
Entry Details
US Patent

TargetNon-receptor tyrosine-protein kinase TYK2(Human)
Array Biopharma

US Patent
LigandChemical structure of BindingDB Monomer ID 325348BDBM325348(N,N-dimethyl-2-(4-(4-(1- (pentan-3-yl)-1H-pyrazol-...)
Affinity DataIC50: 55nMAssay Description:Compounds of Formula I were screened for their ability to inhibit Tyk2 using the general enzyme inhibition assay method, in which the assay mixture c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2021
Entry Details
US Patent

TargetTyrosine-protein kinase JAK2(Human)
Array Biopharma

US Patent
LigandChemical structure of BindingDB Monomer ID 325347BDBM325347(N-methyl-N-(2-(4-(4-(1- (pentan-3-yl)-1H-pyrazol-4...)
Affinity DataIC50: 55nMAssay Description:Compounds of Formula I were screened for their ability to inhibit JAK2 using the general enzyme inhibition assay method, in which the assay mixture c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2021
Entry Details
US Patent

TargetNon-receptor tyrosine-protein kinase TYK2(Human)
Array Biopharma

US Patent
LigandChemical structure of BindingDB Monomer ID 325477BDBM325477(1-(2-(4-(4-(1-(pentan-3-yl)- 1H-pyrazol-4- yl)pyra...)
Affinity DataIC50: 55nMAssay Description:Compounds of Formula I were screened for their ability to inhibit Tyk2 using the general enzyme inhibition assay method, in which the assay mixture c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2021
Entry Details
US Patent

TargetNon-receptor tyrosine-protein kinase TYK2(Human)
Array Biopharma

US Patent
LigandChemical structure of BindingDB Monomer ID 325347BDBM325347(N-methyl-N-(2-(4-(4-(1- (pentan-3-yl)-1H-pyrazol-4...)
Affinity DataIC50: 55nMAssay Description:Compounds of Formula I were screened for their ability to inhibit Tyk2 using the general enzyme inhibition assay method, in which the assay mixture c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2021
Entry Details
US Patent

TargetTyrosine-protein kinase JAK2(Human)
Array Biopharma

US Patent
LigandChemical structure of BindingDB Monomer ID 325476BDBM325476(6-(1-(2-(3-fluoroazetidin-1- yl)ethyl)-1H-pyrazol-...)
Affinity DataIC50: 55nMAssay Description:Compounds of Formula I were screened for their ability to inhibit JAK2 using the general enzyme inhibition assay method, in which the assay mixture c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2021
Entry Details
US Patent

TargetTyrosine-protein kinase JAK2(Human)
Array Biopharma

US Patent
LigandChemical structure of BindingDB Monomer ID 325346BDBM325346(5-((4-(4-(1-(pentan-3-yl)- 1H-pyrazol-4- yl)pyrazo...)
Affinity DataIC50: 55nMAssay Description:Compounds of Formula I were screened for their ability to inhibit JAK2 using the general enzyme inhibition assay method, in which the assay mixture c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2021
Entry Details
US Patent

TargetNon-receptor tyrosine-protein kinase TYK2(Human)
Array Biopharma

US Patent
LigandChemical structure of BindingDB Monomer ID 325476BDBM325476(6-(1-(2-(3-fluoroazetidin-1- yl)ethyl)-1H-pyrazol-...)
Affinity DataIC50: 55nMAssay Description:Compounds of Formula I were screened for their ability to inhibit Tyk2 using the general enzyme inhibition assay method, in which the assay mixture c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2021
Entry Details
US Patent

TargetNon-receptor tyrosine-protein kinase TYK2(Human)
Array Biopharma

US Patent
LigandChemical structure of BindingDB Monomer ID 325346BDBM325346(5-((4-(4-(1-(pentan-3-yl)- 1H-pyrazol-4- yl)pyrazo...)
Affinity DataIC50: 55nMAssay Description:Compounds of Formula I were screened for their ability to inhibit Tyk2 using the general enzyme inhibition assay method, in which the assay mixture c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2021
Entry Details
US Patent

TargetTyrosine-protein kinase JAK1(Human)
Array Biopharma

US Patent
LigandChemical structure of BindingDB Monomer ID 325346BDBM325346(5-((4-(4-(1-(pentan-3-yl)- 1H-pyrazol-4- yl)pyrazo...)
Affinity DataIC50: 55nMAssay Description:Compounds of Formula I were screened for their ability to inhibit JAK1 using the general enzyme inhibition assay method, in which the assay mixture c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2021
Entry Details
US Patent

TargetTyrosine-protein kinase JAK2(Human)
Array Biopharma

US Patent
LigandChemical structure of BindingDB Monomer ID 325475BDBM325475((S)-6-(1-(2-(3- methoxypyrrolidin-1- yl)ethyl)-1H-...)
Affinity DataIC50: 55nMAssay Description:Compounds of Formula I were screened for their ability to inhibit JAK2 using the general enzyme inhibition assay method, in which the assay mixture c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2021
Entry Details
US Patent

TargetTyrosine-protein kinase JAK2(Human)
Array Biopharma

US Patent
LigandChemical structure of BindingDB Monomer ID 325345BDBM325345(6-(1-(3- (methylsulfonyl)propyl)-1H- pyrazol-4-yl)...)
Affinity DataIC50: 55nMAssay Description:Compounds of Formula I were screened for their ability to inhibit JAK2 using the general enzyme inhibition assay method, in which the assay mixture c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2021
Entry Details
US Patent

TargetNon-receptor tyrosine-protein kinase TYK2(Human)
Array Biopharma

US Patent
LigandChemical structure of BindingDB Monomer ID 325475BDBM325475((S)-6-(1-(2-(3- methoxypyrrolidin-1- yl)ethyl)-1H-...)
Affinity DataIC50: 55nMAssay Description:Compounds of Formula I were screened for their ability to inhibit Tyk2 using the general enzyme inhibition assay method, in which the assay mixture c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2021
Entry Details
US Patent

TargetNon-receptor tyrosine-protein kinase TYK2(Human)
Array Biopharma

US Patent
LigandChemical structure of BindingDB Monomer ID 325345BDBM325345(6-(1-(3- (methylsulfonyl)propyl)-1H- pyrazol-4-yl)...)
Affinity DataIC50: 55nMAssay Description:Compounds of Formula I were screened for their ability to inhibit Tyk2 using the general enzyme inhibition assay method, in which the assay mixture c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2021
Entry Details
US Patent

TargetTyrosine-protein kinase JAK2(Human)
Array Biopharma

US Patent
LigandChemical structure of BindingDB Monomer ID 325474BDBM325474((R)-6-(1-(2-(3- methoxypyrrolidin-1- yl)ethyl)-1H-...)
Affinity DataIC50: 55nMAssay Description:Compounds of Formula I were screened for their ability to inhibit JAK2 using the general enzyme inhibition assay method, in which the assay mixture c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2021
Entry Details
US Patent

TargetTyrosine-protein kinase JAK2(Human)
Array Biopharma

US Patent
LigandChemical structure of BindingDB Monomer ID 325352BDBM325352((R)-2-methyl-3-(4-(4-(1- (pentan-3-yl)-1H-pyrazol-...)
Affinity DataIC50: 55nMAssay Description:Compounds of Formula I were screened for their ability to inhibit JAK2 using the general enzyme inhibition assay method, in which the assay mixture c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2021
Entry Details
US Patent

TargetNon-receptor tyrosine-protein kinase TYK2(Human)
Array Biopharma

US Patent
LigandChemical structure of BindingDB Monomer ID 325482BDBM325482(4-(2-(4-(4-(1-(pentan-3-yl)- 1H-pyrazol-4- yl)pyra...)
Affinity DataIC50: 55nMAssay Description:Compounds of Formula I were screened for their ability to inhibit Tyk2 using the general enzyme inhibition assay method, in which the assay mixture c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2021
Entry Details
US Patent

TargetNon-receptor tyrosine-protein kinase TYK2(Human)
Array Biopharma

US Patent
LigandChemical structure of BindingDB Monomer ID 325352BDBM325352((R)-2-methyl-3-(4-(4-(1- (pentan-3-yl)-1H-pyrazol-...)
Affinity DataIC50: 55nMAssay Description:Compounds of Formula I were screened for their ability to inhibit Tyk2 using the general enzyme inhibition assay method, in which the assay mixture c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2021
Entry Details
US Patent

TargetTyrosine-protein kinase JAK1(Human)
Array Biopharma

US Patent
LigandChemical structure of BindingDB Monomer ID 325352BDBM325352((R)-2-methyl-3-(4-(4-(1- (pentan-3-yl)-1H-pyrazol-...)
Affinity DataIC50: 55nMAssay Description:Compounds of Formula I were screened for their ability to inhibit JAK1 using the general enzyme inhibition assay method, in which the assay mixture c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2021
Entry Details
US Patent

TargetTyrosine-protein kinase JAK2(Human)
Array Biopharma

US Patent
LigandChemical structure of BindingDB Monomer ID 325481BDBM325481((R)-1-methyl-3-((2-(4-(4-(1- (pentan-3-yl)-1H-pyra...)
Affinity DataIC50: 55nMAssay Description:Compounds of Formula I were screened for their ability to inhibit JAK2 using the general enzyme inhibition assay method, in which the assay mixture c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2021
Entry Details
US Patent

TargetNon-receptor tyrosine-protein kinase TYK2(Human)
Array Biopharma

US Patent
LigandChemical structure of BindingDB Monomer ID 325351BDBM325351(3-(4-(4-(1-(pentan-3-yl)-1H- pyrazol-4-yl)pyrazolo...)
Affinity DataIC50: 55nMAssay Description:Compounds of Formula I were screened for their ability to inhibit Tyk2 using the general enzyme inhibition assay method, in which the assay mixture c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2021
Entry Details
US Patent

TargetTyrosine-protein kinase JAK2(Human)
Array Biopharma

US Patent
LigandChemical structure of BindingDB Monomer ID 325480BDBM325480((S)-1-methyl-3-((2-(4-(4-(1- (pentan-3-yl)-1H-pyra...)
Affinity DataIC50: 55nMAssay Description:Compounds of Formula I were screened for their ability to inhibit JAK2 using the general enzyme inhibition assay method, in which the assay mixture c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2021
Entry Details
US Patent

TargetNon-receptor tyrosine-protein kinase TYK2(Human)
Array Biopharma

US Patent
LigandChemical structure of BindingDB Monomer ID 325480BDBM325480((S)-1-methyl-3-((2-(4-(4-(1- (pentan-3-yl)-1H-pyra...)
Affinity DataIC50: 55nMAssay Description:Compounds of Formula I were screened for their ability to inhibit Tyk2 using the general enzyme inhibition assay method, in which the assay mixture c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2021
Entry Details
US Patent

TargetTyrosine-protein kinase JAK2(Human)
Array Biopharma

US Patent
LigandChemical structure of BindingDB Monomer ID 325479BDBM325479((S)-1-(2-(4-(4-(1-(pentan-3- yl)-1H-pyrazol-4- yl)...)
Affinity DataIC50: 55nMAssay Description:Compounds of Formula I were screened for their ability to inhibit JAK2 using the general enzyme inhibition assay method, in which the assay mixture c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2021
Entry Details
US Patent

TargetTyrosine-protein kinase JAK2(Human)
Array Biopharma

US Patent
LigandChemical structure of BindingDB Monomer ID 325349BDBM325349(4-((4-(4-(1-(pentan-3-yl)- 1H-pyrazol-4- yl)pyrazo...)
Affinity DataIC50: 55nMAssay Description:Compounds of Formula I were screened for their ability to inhibit JAK2 using the general enzyme inhibition assay method, in which the assay mixture c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2021
Entry Details
US Patent

TargetNon-receptor tyrosine-protein kinase TYK2(Human)
Array Biopharma

US Patent
LigandChemical structure of BindingDB Monomer ID 325479BDBM325479((S)-1-(2-(4-(4-(1-(pentan-3- yl)-1H-pyrazol-4- yl)...)
Affinity DataIC50: 55nMAssay Description:Compounds of Formula I were screened for their ability to inhibit Tyk2 using the general enzyme inhibition assay method, in which the assay mixture c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2021
Entry Details
US Patent

TargetNon-receptor tyrosine-protein kinase TYK2(Human)
Array Biopharma

US Patent
LigandChemical structure of BindingDB Monomer ID 325349BDBM325349(4-((4-(4-(1-(pentan-3-yl)- 1H-pyrazol-4- yl)pyrazo...)
Affinity DataIC50: 55nMAssay Description:Compounds of Formula I were screened for their ability to inhibit Tyk2 using the general enzyme inhibition assay method, in which the assay mixture c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2021
Entry Details
US Patent

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