Compile Data Set for Download or QSAR
Report error Found 582 Enz. Inhib. hit(s) with all data for entry = 9337
Target5-hydroxytryptamine receptor 1A(Human)
Sumitomo Dainippon Pharma

US Patent
LigandChemical structure of BindingDB Monomer ID 458528BDBM458528(US10745401, Example 107 | 2-{2-[4-(1,2-Benzoisothi...)
Affinity DataKi:  0.0300nMAssay Description:Binding affinity of the present compound for human 5-HT1A receptor, human 5-HT2A receptor, and human D2 receptor was measured by the following proced...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2021
Entry Details
US Patent

Target5-hydroxytryptamine receptor 1A(Human)
Sumitomo Dainippon Pharma

US Patent
LigandChemical structure of BindingDB Monomer ID 458528BDBM458528(US10745401, Example 107 | 2-{2-[4-(1,2-Benzoisothi...)
Affinity DataKi:  0.0800nMAssay Description:Binding affinity of the present compound for human 5-HT1A receptor, human 5-HT2A receptor, and human D2 receptor was measured by the following proced...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2021
Entry Details
US Patent

Target5-hydroxytryptamine receptor 1A(Human)
Sumitomo Dainippon Pharma

US Patent
LigandChemical structure of BindingDB Monomer ID 458557BDBM458557(US10745401, Example 31 | US11466007, Example 31 | ...)
Affinity DataKi:  0.0800nMAssay Description:Binding affinity of the present compound for human 5-HT1A receptor, human 5-HT2A receptor, and human D2 receptor was measured by the following proced...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2021
Entry Details
US Patent

Target5-hydroxytryptamine receptor 1A(Human)
Sumitomo Dainippon Pharma

US Patent
LigandChemical structure of BindingDB Monomer ID 458588BDBM458588(US10745401, Example 62 | US11466007, Example 62 | ...)
Affinity DataKi:  0.100nMAssay Description:Binding affinity of the present compound for human 5-HT1A receptor, human 5-HT2A receptor, and human D2 receptor was measured by the following proced...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2021
Entry Details
US Patent

Target5-hydroxytryptamine receptor 2A(Human)
Sumitomo Dainippon Pharma

US Patent
LigandChemical structure of BindingDB Monomer ID 458582BDBM458582(US10745401, Example 56 | US11466007, Example 56 | ...)
Affinity DataKi:  0.110nMAssay Description:Binding affinity of the present compound for human 5-HT1A receptor, human 5-HT2A receptor, and human D2 receptor was measured by the following proced...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2021
Entry Details
US Patent

Target5-hydroxytryptamine receptor 1A(Human)
Sumitomo Dainippon Pharma

US Patent
LigandChemical structure of BindingDB Monomer ID 458613BDBM458613(US10745401, Example 87 | US11466007, Example 87 | ...)
Affinity DataKi:  0.120nMAssay Description:Binding affinity of the present compound for human 5-HT1A receptor, human 5-HT2A receptor, and human D2 receptor was measured by the following proced...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2021
Entry Details
US Patent

Target5-hydroxytryptamine receptor 1A(Human)
Sumitomo Dainippon Pharma

US Patent
LigandChemical structure of BindingDB Monomer ID 458694BDBM458694(US10745401, Example 167 | US11466007, Example 167 ...)
Affinity DataKi:  0.140nMAssay Description:Binding affinity of the present compound for human 5-HT1A receptor, human 5-HT2A receptor, and human D2 receptor was measured by the following proced...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2021
Entry Details
US Patent

Target5-hydroxytryptamine receptor 2A(Human)
Sumitomo Dainippon Pharma

US Patent
LigandChemical structure of BindingDB Monomer ID 458591BDBM458591(US10745401, Example 65 | US11466007, Example 65 | ...)
Affinity DataKi:  0.150nMAssay Description:Binding affinity of the present compound for human 5-HT1A receptor, human 5-HT2A receptor, and human D2 receptor was measured by the following proced...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2021
Entry Details
US Patent

Target5-hydroxytryptamine receptor 1A(Human)
Sumitomo Dainippon Pharma

US Patent
LigandChemical structure of BindingDB Monomer ID 458540BDBM458540(US10745401, Example 14 | US11466007, Example 20)
Affinity DataKi:  0.150nMAssay Description:Binding affinity of the present compound for human 5-HT1A receptor, human 5-HT2A receptor, and human D2 receptor was measured by the following proced...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2021
Entry Details
US Patent

Target5-hydroxytryptamine receptor 1A(Human)
Sumitomo Dainippon Pharma

US Patent
LigandChemical structure of BindingDB Monomer ID 458634BDBM458634(2-{2-[4-(1,2-Benzoisothiazol-3-yl)piperazin-1-yl]e...)
Affinity DataKi:  0.160nMAssay Description:Binding affinity of the present compound for human 5-HT1A receptor, human 5-HT2A receptor, and human D2 receptor was measured by the following proced...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2021
Entry Details
US Patent

Target5-hydroxytryptamine receptor 1A(Human)
Sumitomo Dainippon Pharma

US Patent
LigandChemical structure of BindingDB Monomer ID 458693BDBM458693(US10745401, Example 166 | US11466007, Example 166 ...)
Affinity DataKi:  0.170nMAssay Description:Binding affinity of the present compound for human 5-HT1A receptor, human 5-HT2A receptor, and human D2 receptor was measured by the following proced...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2021
Entry Details
US Patent

Target5-hydroxytryptamine receptor 2A(Human)
Sumitomo Dainippon Pharma

US Patent
LigandChemical structure of BindingDB Monomer ID 458695BDBM458695(US10745401, Example 168 | US11466007, Example 168 ...)
Affinity DataKi:  0.180nMAssay Description:Binding affinity of the present compound for human 5-HT1A receptor, human 5-HT2A receptor, and human D2 receptor was measured by the following proced...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2021
Entry Details
US Patent

Target5-hydroxytryptamine receptor 1A(Human)
Sumitomo Dainippon Pharma

US Patent
LigandChemical structure of BindingDB Monomer ID 458605BDBM458605(US10745401, Example 79 | US11466007, Example 79 | ...)
Affinity DataKi:  0.190nMAssay Description:Binding affinity of the present compound for human 5-HT1A receptor, human 5-HT2A receptor, and human D2 receptor was measured by the following proced...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2021
Entry Details
US Patent

Target5-hydroxytryptamine receptor 1A(Human)
Sumitomo Dainippon Pharma

US Patent
LigandChemical structure of BindingDB Monomer ID 458551BDBM458551(US10745401, Example 25 | US11466007, Example 25 | ...)
Affinity DataKi:  0.190nMAssay Description:Binding affinity of the present compound for human 5-HT1A receptor, human 5-HT2A receptor, and human D2 receptor was measured by the following proced...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2021
Entry Details
US Patent

Target5-hydroxytryptamine receptor 1A(Human)
Sumitomo Dainippon Pharma

US Patent
LigandChemical structure of BindingDB Monomer ID 458570BDBM458570(US10745401, Example 44 | US11466007, Example 44 | ...)
Affinity DataKi:  0.220nMAssay Description:Binding affinity of the present compound for human 5-HT1A receptor, human 5-HT2A receptor, and human D2 receptor was measured by the following proced...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2021
Entry Details
US Patent

Target5-hydroxytryptamine receptor 2A(Human)
Sumitomo Dainippon Pharma

US Patent
LigandChemical structure of BindingDB Monomer ID 458555BDBM458555(US10745401, Example 29 | US11466007, Example 29 | ...)
Affinity DataKi:  0.230nMAssay Description:Binding affinity of the present compound for human 5-HT1A receptor, human 5-HT2A receptor, and human D2 receptor was measured by the following proced...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2021
Entry Details
US Patent

Target5-hydroxytryptamine receptor 2A(Human)
Sumitomo Dainippon Pharma

US Patent
LigandChemical structure of BindingDB Monomer ID 458587BDBM458587(US10745401, Example 61 | US11466007, Example 61 | ...)
Affinity DataKi:  0.230nMAssay Description:Binding affinity of the present compound for human 5-HT1A receptor, human 5-HT2A receptor, and human D2 receptor was measured by the following proced...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2021
Entry Details
US Patent

Target5-hydroxytryptamine receptor 1A(Human)
Sumitomo Dainippon Pharma

US Patent
LigandChemical structure of BindingDB Monomer ID 458577BDBM458577(US10745401, Example 51 | US11466007, Example 51 | ...)
Affinity DataKi:  0.230nMAssay Description:Binding affinity of the present compound for human 5-HT1A receptor, human 5-HT2A receptor, and human D2 receptor was measured by the following proced...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2021
Entry Details
US Patent

Target5-hydroxytryptamine receptor 1A(Human)
Sumitomo Dainippon Pharma

US Patent
LigandChemical structure of BindingDB Monomer ID 458603BDBM458603(US10745401, Example 77 | US11466007, Example 77 | ...)
Affinity DataKi:  0.240nMAssay Description:Binding affinity of the present compound for human 5-HT1A receptor, human 5-HT2A receptor, and human D2 receptor was measured by the following proced...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2021
Entry Details
US Patent

Target5-hydroxytryptamine receptor 1A(Human)
Sumitomo Dainippon Pharma

US Patent
LigandChemical structure of BindingDB Monomer ID 458628BDBM458628(7-{2-[4-(1,2-Benzoisothiazol-3-yl)piperazin-1-yl]e...)
Affinity DataKi:  0.25nMAssay Description:Binding affinity of the present compound for human 5-HT1A receptor, human 5-HT2A receptor, and human D2 receptor was measured by the following proced...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2021
Entry Details
US Patent

Target5-hydroxytryptamine receptor 2A(Human)
Sumitomo Dainippon Pharma

US Patent
LigandChemical structure of BindingDB Monomer ID 458530BDBM458530(US10745401, Example 125 | US10745401, Example 4 | ...)
Affinity DataKi:  0.270nMAssay Description:Binding affinity of the present compound for human 5-HT1A receptor, human 5-HT2A receptor, and human D2 receptor was measured by the following proced...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2021
Entry Details
US Patent

Target5-hydroxytryptamine receptor 2A(Human)
Sumitomo Dainippon Pharma

US Patent
LigandChemical structure of BindingDB Monomer ID 458570BDBM458570(US10745401, Example 44 | US11466007, Example 44 | ...)
Affinity DataKi:  0.330nMAssay Description:Binding affinity of the present compound for human 5-HT1A receptor, human 5-HT2A receptor, and human D2 receptor was measured by the following proced...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2021
Entry Details
US Patent

Target5-hydroxytryptamine receptor 2A(Human)
Sumitomo Dainippon Pharma

US Patent
LigandChemical structure of BindingDB Monomer ID 458718BDBM458718(5-{2-[4-(1,2-Benzoisoxazol-3-yl)piperidin-1-yl]eth...)
Affinity DataKi:  0.340nMAssay Description:Binding affinity of the present compound for human 5-HT1A receptor, human 5-HT2A receptor, and human D2 receptor was measured by the following proced...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2021
Entry Details
US Patent

Target5-hydroxytryptamine receptor 2A(Human)
Sumitomo Dainippon Pharma

US Patent
LigandChemical structure of BindingDB Monomer ID 458563BDBM458563(5-{2-[4-(1,2-Benzoisoxazol-3-yl)piperidin-1-yl]eth...)
Affinity DataKi:  0.370nMAssay Description:Binding affinity of the present compound for human 5-HT1A receptor, human 5-HT2A receptor, and human D2 receptor was measured by the following proced...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2021
Entry Details
US Patent

Target5-hydroxytryptamine receptor 2A(Human)
Sumitomo Dainippon Pharma

US Patent
LigandChemical structure of BindingDB Monomer ID 458600BDBM458600(US10745401, Example 74 | US11466007, Example 74 | ...)
Affinity DataKi:  0.380nMAssay Description:Binding affinity of the present compound for human 5-HT1A receptor, human 5-HT2A receptor, and human D2 receptor was measured by the following proced...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2021
Entry Details
US Patent

Target5-hydroxytryptamine receptor 1A(Human)
Sumitomo Dainippon Pharma

US Patent
LigandChemical structure of BindingDB Monomer ID 458679BDBM458679(US10745401, Example 152 | US11466007, Example 152 ...)
Affinity DataKi:  0.380nMAssay Description:Binding affinity of the present compound for human 5-HT1A receptor, human 5-HT2A receptor, and human D2 receptor was measured by the following proced...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2021
Entry Details
US Patent

Target5-hydroxytryptamine receptor 2A(Human)
Sumitomo Dainippon Pharma

US Patent
LigandChemical structure of BindingDB Monomer ID 458528BDBM458528(US10745401, Example 107 | 2-{2-[4-(1,2-Benzoisothi...)
Affinity DataKi:  0.400nMAssay Description:Binding affinity of the present compound for human 5-HT1A receptor, human 5-HT2A receptor, and human D2 receptor was measured by the following proced...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2021
Entry Details
US Patent

Target5-hydroxytryptamine receptor 2A(Human)
Sumitomo Dainippon Pharma

US Patent
LigandChemical structure of BindingDB Monomer ID 458719BDBM458719(5-{2-[4-(1,2-Benzoisoxazol-3-yl)piperidin-1-yl]eth...)
Affinity DataKi:  0.410nMAssay Description:Binding affinity of the present compound for human 5-HT1A receptor, human 5-HT2A receptor, and human D2 receptor was measured by the following proced...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2021
Entry Details
US Patent

Target5-hydroxytryptamine receptor 1A(Human)
Sumitomo Dainippon Pharma

US Patent
LigandChemical structure of BindingDB Monomer ID 458630BDBM458630(US10745401, Example 104 | US11466007, Example 104 ...)
Affinity DataKi:  0.410nMAssay Description:Binding affinity of the present compound for human 5-HT1A receptor, human 5-HT2A receptor, and human D2 receptor was measured by the following proced...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2021
Entry Details
US Patent

Target5-hydroxytryptamine receptor 2A(Human)
Sumitomo Dainippon Pharma

US Patent
LigandChemical structure of BindingDB Monomer ID 458585BDBM458585(US10745401, Example 59 | US11466007, Example 59 | ...)
Affinity DataKi:  0.450nMAssay Description:Binding affinity of the present compound for human 5-HT1A receptor, human 5-HT2A receptor, and human D2 receptor was measured by the following proced...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2021
Entry Details
US Patent

Target5-hydroxytryptamine receptor 1A(Human)
Sumitomo Dainippon Pharma

US Patent
LigandChemical structure of BindingDB Monomer ID 458562BDBM458562(5-{2-[4-(1,2-Benzoisothiazol-3-yl)piperazin-1-yl]e...)
Affinity DataKi:  0.450nMAssay Description:Binding affinity of the present compound for human 5-HT1A receptor, human 5-HT2A receptor, and human D2 receptor was measured by the following proced...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2021
Entry Details
US Patent

Target5-hydroxytryptamine receptor 2A(Human)
Sumitomo Dainippon Pharma

US Patent
LigandChemical structure of BindingDB Monomer ID 458652BDBM458652(US10745401, Example 126 | US11466007, Example 126 ...)
Affinity DataKi:  0.450nMAssay Description:Binding affinity of the present compound for human 5-HT1A receptor, human 5-HT2A receptor, and human D2 receptor was measured by the following proced...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2021
Entry Details
US Patent

Target5-hydroxytryptamine receptor 2A(Human)
Sumitomo Dainippon Pharma

US Patent
LigandChemical structure of BindingDB Monomer ID 458632BDBM458632(5-{2-[4-(1,2-Benzoisothiazol-3-yl)piperazin-1-yl]e...)
Affinity DataKi:  0.460nMAssay Description:Binding affinity of the present compound for human 5-HT1A receptor, human 5-HT2A receptor, and human D2 receptor was measured by the following proced...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2021
Entry Details
US Patent

Target5-hydroxytryptamine receptor 1A(Human)
Sumitomo Dainippon Pharma

US Patent
LigandChemical structure of BindingDB Monomer ID 458604BDBM458604(US10745401, Example 78 | US11466007, Example 78)
Affinity DataKi:  0.460nMAssay Description:Binding affinity of the present compound for human 5-HT1A receptor, human 5-HT2A receptor, and human D2 receptor was measured by the following proced...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2021
Entry Details
US Patent

Target5-hydroxytryptamine receptor 2A(Human)
Sumitomo Dainippon Pharma

US Patent
LigandChemical structure of BindingDB Monomer ID 458528BDBM458528(US10745401, Example 107 | 2-{2-[4-(1,2-Benzoisothi...)
Affinity DataKi:  0.460nMAssay Description:Binding affinity of the present compound for human 5-HT1A receptor, human 5-HT2A receptor, and human D2 receptor was measured by the following proced...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2021
Entry Details
US Patent

Target5-hydroxytryptamine receptor 1A(Human)
Sumitomo Dainippon Pharma

US Patent
LigandChemical structure of BindingDB Monomer ID 458629BDBM458629(5-{2-[4-(1,2-Benzoisoxazol-3-yl)piperidin-1-yl]eth...)
Affinity DataKi:  0.470nMAssay Description:Binding affinity of the present compound for human 5-HT1A receptor, human 5-HT2A receptor, and human D2 receptor was measured by the following proced...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2021
Entry Details
US Patent

Target5-hydroxytryptamine receptor 2A(Human)
Sumitomo Dainippon Pharma

US Patent
LigandChemical structure of BindingDB Monomer ID 458557BDBM458557(US10745401, Example 31 | US11466007, Example 31 | ...)
Affinity DataKi:  0.470nMAssay Description:Binding affinity of the present compound for human 5-HT1A receptor, human 5-HT2A receptor, and human D2 receptor was measured by the following proced...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2021
Entry Details
US Patent

Target5-hydroxytryptamine receptor 2A(Human)
Sumitomo Dainippon Pharma

US Patent
LigandChemical structure of BindingDB Monomer ID 458645BDBM458645(US10745401, Example 119 | US11466007, Example 119 ...)
Affinity DataKi:  0.480nMAssay Description:Binding affinity of the present compound for human 5-HT1A receptor, human 5-HT2A receptor, and human D2 receptor was measured by the following proced...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2021
Entry Details
US Patent

Target5-hydroxytryptamine receptor 2A(Human)
Sumitomo Dainippon Pharma

US Patent
LigandChemical structure of BindingDB Monomer ID 458536BDBM458536(US10745401, Example 10 | US11466007, Example 10 | ...)
Affinity DataKi:  0.490nMAssay Description:Binding affinity of the present compound for human 5-HT1A receptor, human 5-HT2A receptor, and human D2 receptor was measured by the following proced...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2021
Entry Details
US Patent

Target5-hydroxytryptamine receptor 1A(Human)
Sumitomo Dainippon Pharma

US Patent
LigandChemical structure of BindingDB Monomer ID 458541BDBM458541(US10745401, Example 15 | US11466007, Example 15 | ...)
Affinity DataKi:  0.510nMAssay Description:Binding affinity of the present compound for human 5-HT1A receptor, human 5-HT2A receptor, and human D2 receptor was measured by the following proced...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2021
Entry Details
US Patent

Target5-hydroxytryptamine receptor 2A(Human)
Sumitomo Dainippon Pharma

US Patent
LigandChemical structure of BindingDB Monomer ID 458604BDBM458604(US10745401, Example 78 | US11466007, Example 78)
Affinity DataKi:  0.520nMAssay Description:Binding affinity of the present compound for human 5-HT1A receptor, human 5-HT2A receptor, and human D2 receptor was measured by the following proced...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2021
Entry Details
US Patent

Target5-hydroxytryptamine receptor 2A(Human)
Sumitomo Dainippon Pharma

US Patent
LigandChemical structure of BindingDB Monomer ID 458599BDBM458599(US10745401, Example 73 | US11466007, Example 73 | ...)
Affinity DataKi:  0.540nMAssay Description:Binding affinity of the present compound for human 5-HT1A receptor, human 5-HT2A receptor, and human D2 receptor was measured by the following proced...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2021
Entry Details
US Patent

Target5-hydroxytryptamine receptor 1A(Human)
Sumitomo Dainippon Pharma

US Patent
LigandChemical structure of BindingDB Monomer ID 458617BDBM458617(US10745401, Example 91 | US11466007, Example 91 | ...)
Affinity DataKi:  0.570nMAssay Description:Binding affinity of the present compound for human 5-HT1A receptor, human 5-HT2A receptor, and human D2 receptor was measured by the following proced...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2021
Entry Details
US Patent

Target5-hydroxytryptamine receptor 2A(Human)
Sumitomo Dainippon Pharma

US Patent
LigandChemical structure of BindingDB Monomer ID 458716BDBM458716(5-{2-[4-(1,2-Benzoisoxazol-3-yl)piperidin-1-yl]eth...)
Affinity DataKi:  0.590nMAssay Description:Binding affinity of the present compound for human 5-HT1A receptor, human 5-HT2A receptor, and human D2 receptor was measured by the following proced...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2021
Entry Details
US Patent

Target5-hydroxytryptamine receptor 2A(Human)
Sumitomo Dainippon Pharma

US Patent
LigandChemical structure of BindingDB Monomer ID 458696BDBM458696(US10745401, Example 169 | US11466007, Example 169 ...)
Affinity DataKi:  0.600nMAssay Description:Binding affinity of the present compound for human 5-HT1A receptor, human 5-HT2A receptor, and human D2 receptor was measured by the following proced...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2021
Entry Details
US Patent

Target5-hydroxytryptamine receptor 1A(Human)
Sumitomo Dainippon Pharma

US Patent
LigandChemical structure of BindingDB Monomer ID 458608BDBM458608(US10745401, Example 82 | US11466007, Example 82)
Affinity DataKi:  0.610nMAssay Description:Binding affinity of the present compound for human 5-HT1A receptor, human 5-HT2A receptor, and human D2 receptor was measured by the following proced...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2021
Entry Details
US Patent

Target5-hydroxytryptamine receptor 2A(Human)
Sumitomo Dainippon Pharma

US Patent
LigandChemical structure of BindingDB Monomer ID 458562BDBM458562(5-{2-[4-(1,2-Benzoisothiazol-3-yl)piperazin-1-yl]e...)
Affinity DataKi:  0.620nMAssay Description:Binding affinity of the present compound for human 5-HT1A receptor, human 5-HT2A receptor, and human D2 receptor was measured by the following proced...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2021
Entry Details
US Patent

Target5-hydroxytryptamine receptor 1A(Human)
Sumitomo Dainippon Pharma

US Patent
LigandChemical structure of BindingDB Monomer ID 458555BDBM458555(US10745401, Example 29 | US11466007, Example 29 | ...)
Affinity DataKi:  0.680nMAssay Description:Binding affinity of the present compound for human 5-HT1A receptor, human 5-HT2A receptor, and human D2 receptor was measured by the following proced...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2021
Entry Details
US Patent

Target5-hydroxytryptamine receptor 2A(Human)
Sumitomo Dainippon Pharma

US Patent
LigandChemical structure of BindingDB Monomer ID 458589BDBM458589(US10745401, Example 63 | US11466007, Example 63 | ...)
Affinity DataKi:  0.690nMAssay Description:Binding affinity of the present compound for human 5-HT1A receptor, human 5-HT2A receptor, and human D2 receptor was measured by the following proced...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2021
Entry Details
US Patent

Target5-hydroxytryptamine receptor 2A(Human)
Sumitomo Dainippon Pharma

US Patent
LigandChemical structure of BindingDB Monomer ID 458630BDBM458630(US10745401, Example 104 | US11466007, Example 104 ...)
Affinity DataKi:  0.690nMAssay Description:Binding affinity of the present compound for human 5-HT1A receptor, human 5-HT2A receptor, and human D2 receptor was measured by the following proced...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2021
Entry Details
US Patent

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