Compile Data Set for Download or QSAR
Report error Found 45 Enz. Inhib. hit(s) with all data for entry = 9452
TargetMetabotropic glutamate receptor 2(Human)
Shanghai Institute of Material Medica, Chinese Academy of Sciences

US Patent
LigandChemical structure of BindingDB Monomer ID 466960BDBM466960(7-(Benzo[d][1,3]dioxol-5-yl)-8-chloro- 3-((2,2-dif...)
Affinity DataEC50:  62.3nMAssay Description:Experimental materials: HEK/mGluR2 cell line (human GluR2 transfected HEK cell line), DMEM (FBS) medium, positive control LY487379 (purchased from si...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/1/2021
Entry Details
US Patent

TargetMetabotropic glutamate receptor 2(Human)
Shanghai Institute of Material Medica, Chinese Academy of Sciences

US Patent
LigandChemical structure of BindingDB Monomer ID 466957BDBM466957(Methyl 4-(8-Chloro-3- ((2,2-difluorocyclopropyl) m...)
Affinity DataEC50:  87.9nMAssay Description:Experimental materials: HEK/mGluR2 cell line (human GluR2 transfected HEK cell line), DMEM (FBS) medium, positive control LY487379 (purchased from si...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/1/2021
Entry Details
US Patent

TargetMetabotropic glutamate receptor 2(Human)
Shanghai Institute of Material Medica, Chinese Academy of Sciences

US Patent
LigandChemical structure of BindingDB Monomer ID 466952BDBM466952(7-(Benzo[d][1,3]dioxol-5-yl)- 3-((2,2-difluorocycl...)
Affinity DataEC50:  108nMAssay Description:Experimental materials: HEK/mGluR2 cell line (human GluR2 transfected HEK cell line), DMEM (FBS) medium, positive control LY487379 (purchased from si...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/1/2021
Entry Details
US Patent

TargetMetabotropic glutamate receptor 2(Human)
Shanghai Institute of Material Medica, Chinese Academy of Sciences

US Patent
LigandChemical structure of BindingDB Monomer ID 466956BDBM466956(8-chloro-3-((2,2-difluorocyclopropyl) methyl)-7-(3...)
Affinity DataEC50:  118nMAssay Description:Experimental materials: HEK/mGluR2 cell line (human GluR2 transfected HEK cell line), DMEM (FBS) medium, positive control LY487379 (purchased from si...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/1/2021
Entry Details
US Patent

TargetMetabotropic glutamate receptor 2(Human)
Shanghai Institute of Material Medica, Chinese Academy of Sciences

US Patent
LigandChemical structure of BindingDB Monomer ID 466953BDBM466953(8-chloro-3-((2,2-difluorocyclopropyl) methyl)-7-(m...)
Affinity DataEC50:  130nMAssay Description:Experimental materials: HEK/mGluR2 cell line (human GluR2 transfected HEK cell line), DMEM (FBS) medium, positive control LY487379 (purchased from si...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/1/2021
Entry Details
US Patent

TargetPotassium voltage-gated channel subfamily H member 2(Human)
Shanghai Institute of Material Medica, Chinese Academy of Sciences

US Patent
LigandChemical structure of BindingDB Monomer ID 50005836BDBM50005836(4-amino-5-chloro-N-(1-(3-(4-fluorophenoxy)propyl)-...)
Affinity DataIC50: 130nMAssay Description:Experimental method: hERG patch clamp detection methodExperimental procedure: Compound preparation: the stock solution of a compound was diluted with...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/1/2021
Entry Details
US Patent

TargetMetabotropic glutamate receptor 2(Human)
Shanghai Institute of Material Medica, Chinese Academy of Sciences

US Patent
LigandChemical structure of BindingDB Monomer ID 466941BDBM466941(3-((2,2-difluorocyclopropyl)methyl)- 7-(m-tolyl)-[...)
Affinity DataEC50:  143nMAssay Description:Experimental materials: HEK/mGluR2 cell line (human GluR2 transfected HEK cell line), DMEM (FBS) medium, positive control LY487379 (purchased from si...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/1/2021
Entry Details
US Patent

TargetMetabotropic glutamate receptor 2(Human)
Shanghai Institute of Material Medica, Chinese Academy of Sciences

US Patent
LigandChemical structure of BindingDB Monomer ID 466954BDBM466954(8-chloro-3-((2,2-difluorocyclopropyl) methyl)-7-(3...)
Affinity DataEC50:  190nMAssay Description:Experimental materials: HEK/mGluR2 cell line (human GluR2 transfected HEK cell line), DMEM (FBS) medium, positive control LY487379 (purchased from si...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/1/2021
Entry Details
US Patent

TargetMetabotropic glutamate receptor 2(Human)
Shanghai Institute of Material Medica, Chinese Academy of Sciences

US Patent
LigandChemical structure of BindingDB Monomer ID 466959BDBM466959(8-chloro-3-((2,2-difluorocyclopropyl) methyl)-7-(2...)
Affinity DataEC50:  215nMAssay Description:Experimental materials: HEK/mGluR2 cell line (human GluR2 transfected HEK cell line), DMEM (FBS) medium, positive control LY487379 (purchased from si...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/1/2021
Entry Details
US Patent

TargetMetabotropic glutamate receptor 2(Human)
Shanghai Institute of Material Medica, Chinese Academy of Sciences

US Patent
LigandChemical structure of BindingDB Monomer ID 466944BDBM466944(2-(4-(3-((2,2-difluorocyclopropyl) methyl)-[1,2,4]...)
Affinity DataEC50:  226nMAssay Description:Experimental materials: HEK/mGluR2 cell line (human GluR2 transfected HEK cell line), DMEM (FBS) medium, positive control LY487379 (purchased from si...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/1/2021
Entry Details
US Patent

TargetMetabotropic glutamate receptor 2(Human)
Shanghai Institute of Material Medica, Chinese Academy of Sciences

US Patent
LigandChemical structure of BindingDB Monomer ID 50130608BDBM50130608(2,2,2-Trifluoro-ethanesulfonic acid [4-(2-methoxy-...)
Affinity DataEC50:  230nMAssay Description:Experimental materials: HEK/mGluR2 cell line (human GluR2 transfected HEK cell line), DMEM (FBS) medium, positive control LY487379 (purchased from si...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/1/2021
Entry Details
US Patent

TargetMetabotropic glutamate receptor 2(Human)
Shanghai Institute of Material Medica, Chinese Academy of Sciences

US Patent
LigandChemical structure of BindingDB Monomer ID 466958BDBM466958(Methyl 3-Chloro-4-(8-chloro- 3-((2,2-difluorocyclo...)
Affinity DataEC50:  230nMAssay Description:Experimental materials: HEK/mGluR2 cell line (human GluR2 transfected HEK cell line), DMEM (FBS) medium, positive control LY487379 (purchased from si...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/1/2021
Entry Details
US Patent

TargetMetabotropic glutamate receptor 2(Human)
Shanghai Institute of Material Medica, Chinese Academy of Sciences

US Patent
LigandChemical structure of BindingDB Monomer ID 466949BDBM466949(3-((2,2-difluorocyclopropyl)methyl)- 7-(2,3-benzod...)
Affinity DataEC50:  368nMAssay Description:Experimental materials: HEK/mGluR2 cell line (human GluR2 transfected HEK cell line), DMEM (FBS) medium, positive control LY487379 (purchased from si...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/1/2021
Entry Details
US Patent

TargetMetabotropic glutamate receptor 2(Human)
Shanghai Institute of Material Medica, Chinese Academy of Sciences

US Patent
LigandChemical structure of BindingDB Monomer ID 466943BDBM466943(3-((2,2-difluorocyclopropyl)methyl)- 7-(4-fluoroph...)
Affinity DataEC50:  381nMAssay Description:Experimental materials: HEK/mGluR2 cell line (human GluR2 transfected HEK cell line), DMEM (FBS) medium, positive control LY487379 (purchased from si...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/1/2021
Entry Details
US Patent

TargetMetabotropic glutamate receptor 2(Human)
Shanghai Institute of Material Medica, Chinese Academy of Sciences

US Patent
LigandChemical structure of BindingDB Monomer ID 466948BDBM466948(Methyl 4-(3-((2,2-difluorocyclopropyl) methyl)-[1,...)
Affinity DataEC50:  541nMAssay Description:Experimental materials: HEK/mGluR2 cell line (human GluR2 transfected HEK cell line), DMEM (FBS) medium, positive control LY487379 (purchased from si...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/1/2021
Entry Details
US Patent

TargetMetabotropic glutamate receptor 2(Human)
Shanghai Institute of Material Medica, Chinese Academy of Sciences

US Patent
LigandChemical structure of BindingDB Monomer ID 466951BDBM466951(8-(3-((2,2-difluorocyclopropyl) methyl)-[1,2,4]tri...)
Affinity DataEC50:  612nMAssay Description:Experimental materials: HEK/mGluR2 cell line (human GluR2 transfected HEK cell line), DMEM (FBS) medium, positive control LY487379 (purchased from si...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/1/2021
Entry Details
US Patent

TargetMetabotropic glutamate receptor 2(Human)
Shanghai Institute of Material Medica, Chinese Academy of Sciences

US Patent
LigandChemical structure of BindingDB Monomer ID 466942BDBM466942(3-((2,2-Difluorocyclopropyl)methyl)- 7-(3-fluoroph...)
Affinity DataEC50:  704nMAssay Description:Experimental materials: HEK/mGluR2 cell line (human GluR2 transfected HEK cell line), DMEM (FBS) medium, positive control LY487379 (purchased from si...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/1/2021
Entry Details
US Patent

TargetMetabotropic glutamate receptor 2(Human)
Shanghai Institute of Material Medica, Chinese Academy of Sciences

US Patent
LigandChemical structure of BindingDB Monomer ID 466946BDBM466946(3-((2,2-difluorocyclopropyl)methyl)- 7-(4-fluoro-2...)
Affinity DataEC50:  781nMAssay Description:Experimental materials: HEK/mGluR2 cell line (human GluR2 transfected HEK cell line), DMEM (FBS) medium, positive control LY487379 (purchased from si...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/1/2021
Entry Details
US Patent

TargetMetabotropic glutamate receptor 2(Human)
Shanghai Institute of Material Medica, Chinese Academy of Sciences

US Patent
LigandChemical structure of BindingDB Monomer ID 466950BDBM466950(3-((2,2-difluorocyclopropyl)methyl)- 7-(2,3-benzod...)
Affinity DataEC50:  825nMAssay Description:Experimental materials: HEK/mGluR2 cell line (human GluR2 transfected HEK cell line), DMEM (FBS) medium, positive control LY487379 (purchased from si...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/1/2021
Entry Details
US Patent

TargetMetabotropic glutamate receptor 2(Human)
Shanghai Institute of Material Medica, Chinese Academy of Sciences

US Patent
LigandChemical structure of BindingDB Monomer ID 466945BDBM466945(3-((2,2-difluorocyclopropyl)methyl)- 7-(3-fluoro-4...)
Affinity DataEC50:  849nMAssay Description:Experimental materials: HEK/mGluR2 cell line (human GluR2 transfected HEK cell line), DMEM (FBS) medium, positive control LY487379 (purchased from si...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/1/2021
Entry Details
US Patent

TargetMetabotropic glutamate receptor 2(Human)
Shanghai Institute of Material Medica, Chinese Academy of Sciences

US Patent
LigandChemical structure of BindingDB Monomer ID 466955BDBM466955(8-chloro-3-((2,2-difluorocyclopropyl) methyl)-7-(4...)
Affinity DataEC50:  856nMAssay Description:Experimental materials: HEK/mGluR2 cell line (human GluR2 transfected HEK cell line), DMEM (FBS) medium, positive control LY487379 (purchased from si...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/1/2021
Entry Details
US Patent

TargetMetabotropic glutamate receptor 2(Human)
Shanghai Institute of Material Medica, Chinese Academy of Sciences

US Patent
LigandChemical structure of BindingDB Monomer ID 466947BDBM466947(3-((2,2-difluorocyclopropyl)methyl)- 7-(4-fluoro-3...)
Affinity DataEC50:  868nMAssay Description:Experimental materials: HEK/mGluR2 cell line (human GluR2 transfected HEK cell line), DMEM (FBS) medium, positive control LY487379 (purchased from si...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/1/2021
Entry Details
US Patent

TargetMetabotropic glutamate receptor 2(Human)
Shanghai Institute of Material Medica, Chinese Academy of Sciences

US Patent
LigandChemical structure of BindingDB Monomer ID 466963BDBM466963(US10800776, Example D50)
Affinity DataEC50:  890nMAssay Description:Experimental materials: HEK/mGluR2 cell line (human GluR2 transfected HEK cell line), DMEM (FBS) medium, positive control LY487379 (purchased from si...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/1/2021
Entry Details
US Patent

TargetMetabotropic glutamate receptor 2(Human)
Shanghai Institute of Material Medica, Chinese Academy of Sciences

US Patent
LigandChemical structure of BindingDB Monomer ID 466962BDBM466962(US10800776, Example D45)
Affinity DataEC50:  910nMAssay Description:Experimental materials: HEK/mGluR2 cell line (human GluR2 transfected HEK cell line), DMEM (FBS) medium, positive control LY487379 (purchased from si...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/1/2021
Entry Details
US Patent

TargetMetabotropic glutamate receptor 2(Human)
Shanghai Institute of Material Medica, Chinese Academy of Sciences

US Patent
LigandChemical structure of BindingDB Monomer ID 466961BDBM466961(US10800776, Example D35)
Affinity DataEC50:  970nMAssay Description:Experimental materials: HEK/mGluR2 cell line (human GluR2 transfected HEK cell line), DMEM (FBS) medium, positive control LY487379 (purchased from si...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/1/2021
Entry Details
US Patent

TargetPotassium voltage-gated channel subfamily H member 2(Human)
Shanghai Institute of Material Medica, Chinese Academy of Sciences

US Patent
LigandChemical structure of BindingDB Monomer ID 466960BDBM466960(7-(Benzo[d][1,3]dioxol-5-yl)-8-chloro- 3-((2,2-dif...)
Affinity DataIC50: 4.67E+3nMAssay Description:Experimental method: hERG patch clamp detection methodExperimental procedure: Compound preparation: the stock solution of a compound was diluted with...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/1/2021
Entry Details
US Patent

TargetPotassium voltage-gated channel subfamily H member 2(Human)
Shanghai Institute of Material Medica, Chinese Academy of Sciences

US Patent
LigandChemical structure of BindingDB Monomer ID 466959BDBM466959(8-chloro-3-((2,2-difluorocyclopropyl) methyl)-7-(2...)
Affinity DataIC50: 4.88E+3nMAssay Description:Experimental method: hERG patch clamp detection methodExperimental procedure: Compound preparation: the stock solution of a compound was diluted with...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/1/2021
Entry Details
US Patent

TargetPotassium voltage-gated channel subfamily H member 2(Human)
Shanghai Institute of Material Medica, Chinese Academy of Sciences

US Patent
LigandChemical structure of BindingDB Monomer ID 466958BDBM466958(Methyl 3-Chloro-4-(8-chloro- 3-((2,2-difluorocyclo...)
Affinity DataIC50: 1.08E+4nMAssay Description:Experimental method: hERG patch clamp detection methodExperimental procedure: Compound preparation: the stock solution of a compound was diluted with...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/1/2021
Entry Details
US Patent

TargetPotassium voltage-gated channel subfamily H member 2(Human)
Shanghai Institute of Material Medica, Chinese Academy of Sciences

US Patent
LigandChemical structure of BindingDB Monomer ID 466955BDBM466955(8-chloro-3-((2,2-difluorocyclopropyl) methyl)-7-(4...)
Affinity DataIC50: 1.12E+4nMAssay Description:Experimental method: hERG patch clamp detection methodExperimental procedure: Compound preparation: the stock solution of a compound was diluted with...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/1/2021
Entry Details
US Patent

TargetPotassium voltage-gated channel subfamily H member 2(Human)
Shanghai Institute of Material Medica, Chinese Academy of Sciences

US Patent
LigandChemical structure of BindingDB Monomer ID 466957BDBM466957(Methyl 4-(8-Chloro-3- ((2,2-difluorocyclopropyl) m...)
Affinity DataIC50: 1.34E+4nMAssay Description:Experimental method: hERG patch clamp detection methodExperimental procedure: Compound preparation: the stock solution of a compound was diluted with...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/1/2021
Entry Details
US Patent

TargetPotassium voltage-gated channel subfamily H member 2(Human)
Shanghai Institute of Material Medica, Chinese Academy of Sciences

US Patent
LigandChemical structure of BindingDB Monomer ID 466954BDBM466954(8-chloro-3-((2,2-difluorocyclopropyl) methyl)-7-(3...)
Affinity DataIC50: 1.50E+4nMAssay Description:Experimental method: hERG patch clamp detection methodExperimental procedure: Compound preparation: the stock solution of a compound was diluted with...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/1/2021
Entry Details
US Patent

TargetPotassium voltage-gated channel subfamily H member 2(Human)
Shanghai Institute of Material Medica, Chinese Academy of Sciences

US Patent
LigandChemical structure of BindingDB Monomer ID 466956BDBM466956(8-chloro-3-((2,2-difluorocyclopropyl) methyl)-7-(3...)
Affinity DataIC50: 1.61E+4nMAssay Description:Experimental method: hERG patch clamp detection methodExperimental procedure: Compound preparation: the stock solution of a compound was diluted with...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/1/2021
Entry Details
US Patent

TargetPotassium voltage-gated channel subfamily H member 2(Human)
Shanghai Institute of Material Medica, Chinese Academy of Sciences

US Patent
LigandChemical structure of BindingDB Monomer ID 466948BDBM466948(Methyl 4-(3-((2,2-difluorocyclopropyl) methyl)-[1,...)
Affinity DataIC50: 1.73E+4nMAssay Description:Experimental method: hERG patch clamp detection methodExperimental procedure: Compound preparation: the stock solution of a compound was diluted with...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/1/2021
Entry Details
US Patent

TargetPotassium voltage-gated channel subfamily H member 2(Human)
Shanghai Institute of Material Medica, Chinese Academy of Sciences

US Patent
LigandChemical structure of BindingDB Monomer ID 466944BDBM466944(2-(4-(3-((2,2-difluorocyclopropyl) methyl)-[1,2,4]...)
Affinity DataIC50: 3.19E+4nMAssay Description:Experimental method: hERG patch clamp detection methodExperimental procedure: Compound preparation: the stock solution of a compound was diluted with...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/1/2021
Entry Details
US Patent

TargetPotassium voltage-gated channel subfamily H member 2(Human)
Shanghai Institute of Material Medica, Chinese Academy of Sciences

US Patent
LigandChemical structure of BindingDB Monomer ID 466943BDBM466943(3-((2,2-difluorocyclopropyl)methyl)- 7-(4-fluoroph...)
Affinity DataIC50: 3.19E+4nMAssay Description:Experimental method: hERG patch clamp detection methodExperimental procedure: Compound preparation: the stock solution of a compound was diluted with...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/1/2021
Entry Details
US Patent

TargetPotassium voltage-gated channel subfamily H member 2(Human)
Shanghai Institute of Material Medica, Chinese Academy of Sciences

US Patent
LigandChemical structure of BindingDB Monomer ID 466946BDBM466946(3-((2,2-difluorocyclopropyl)methyl)- 7-(4-fluoro-2...)
Affinity DataIC50: 4.00E+4nMAssay Description:Experimental method: hERG patch clamp detection methodExperimental procedure: Compound preparation: the stock solution of a compound was diluted with...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/1/2021
Entry Details
US Patent

TargetPotassium voltage-gated channel subfamily H member 2(Human)
Shanghai Institute of Material Medica, Chinese Academy of Sciences

US Patent
LigandChemical structure of BindingDB Monomer ID 466947BDBM466947(3-((2,2-difluorocyclopropyl)methyl)- 7-(4-fluoro-3...)
Affinity DataIC50: 4.00E+4nMAssay Description:Experimental method: hERG patch clamp detection methodExperimental procedure: Compound preparation: the stock solution of a compound was diluted with...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/1/2021
Entry Details
US Patent

TargetPotassium voltage-gated channel subfamily H member 2(Human)
Shanghai Institute of Material Medica, Chinese Academy of Sciences

US Patent
LigandChemical structure of BindingDB Monomer ID 466945BDBM466945(3-((2,2-difluorocyclopropyl)methyl)- 7-(3-fluoro-4...)
Affinity DataIC50: 4.00E+4nMAssay Description:Experimental method: hERG patch clamp detection methodExperimental procedure: Compound preparation: the stock solution of a compound was diluted with...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/1/2021
Entry Details
US Patent

TargetPotassium voltage-gated channel subfamily H member 2(Human)
Shanghai Institute of Material Medica, Chinese Academy of Sciences

US Patent
LigandChemical structure of BindingDB Monomer ID 466942BDBM466942(3-((2,2-Difluorocyclopropyl)methyl)- 7-(3-fluoroph...)
Affinity DataIC50: 4.00E+4nMAssay Description:Experimental method: hERG patch clamp detection methodExperimental procedure: Compound preparation: the stock solution of a compound was diluted with...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/1/2021
Entry Details
US Patent

TargetPotassium voltage-gated channel subfamily H member 2(Human)
Shanghai Institute of Material Medica, Chinese Academy of Sciences

US Patent
LigandChemical structure of BindingDB Monomer ID 466941BDBM466941(3-((2,2-difluorocyclopropyl)methyl)- 7-(m-tolyl)-[...)
Affinity DataIC50: 4.00E+4nMAssay Description:Experimental method: hERG patch clamp detection methodExperimental procedure: Compound preparation: the stock solution of a compound was diluted with...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/1/2021
Entry Details
US Patent

TargetPotassium voltage-gated channel subfamily H member 2(Human)
Shanghai Institute of Material Medica, Chinese Academy of Sciences

US Patent
LigandChemical structure of BindingDB Monomer ID 466952BDBM466952(7-(Benzo[d][1,3]dioxol-5-yl)- 3-((2,2-difluorocycl...)
Affinity DataIC50: 4.00E+4nMAssay Description:Experimental method: hERG patch clamp detection methodExperimental procedure: Compound preparation: the stock solution of a compound was diluted with...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/1/2021
Entry Details
US Patent

TargetPotassium voltage-gated channel subfamily H member 2(Human)
Shanghai Institute of Material Medica, Chinese Academy of Sciences

US Patent
LigandChemical structure of BindingDB Monomer ID 466953BDBM466953(8-chloro-3-((2,2-difluorocyclopropyl) methyl)-7-(m...)
Affinity DataIC50: 4.00E+4nMAssay Description:Experimental method: hERG patch clamp detection methodExperimental procedure: Compound preparation: the stock solution of a compound was diluted with...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/1/2021
Entry Details
US Patent

TargetPotassium voltage-gated channel subfamily H member 2(Human)
Shanghai Institute of Material Medica, Chinese Academy of Sciences

US Patent
LigandChemical structure of BindingDB Monomer ID 466950BDBM466950(3-((2,2-difluorocyclopropyl)methyl)- 7-(2,3-benzod...)
Affinity DataIC50: 4.00E+4nMAssay Description:Experimental method: hERG patch clamp detection methodExperimental procedure: Compound preparation: the stock solution of a compound was diluted with...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/1/2021
Entry Details
US Patent

TargetPotassium voltage-gated channel subfamily H member 2(Human)
Shanghai Institute of Material Medica, Chinese Academy of Sciences

US Patent
LigandChemical structure of BindingDB Monomer ID 466951BDBM466951(8-(3-((2,2-difluorocyclopropyl) methyl)-[1,2,4]tri...)
Affinity DataIC50: 4.00E+4nMAssay Description:Experimental method: hERG patch clamp detection methodExperimental procedure: Compound preparation: the stock solution of a compound was diluted with...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/1/2021
Entry Details
US Patent

TargetPotassium voltage-gated channel subfamily H member 2(Human)
Shanghai Institute of Material Medica, Chinese Academy of Sciences

US Patent
LigandChemical structure of BindingDB Monomer ID 466949BDBM466949(3-((2,2-difluorocyclopropyl)methyl)- 7-(2,3-benzod...)
Affinity DataIC50: 4.00E+4nMAssay Description:Experimental method: hERG patch clamp detection methodExperimental procedure: Compound preparation: the stock solution of a compound was diluted with...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/1/2021
Entry Details
US Patent